Gene AqueK294 (A.queenslandica)

AqueK294

Species: A.queenslandica
Alias: AqueK294
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK294.AA Protein None 131 None Fasta, JSON
AqueK294.kin_dom Protein Kinase Domain None 124 None Fasta, JSON

Protein domain

Protein domains of AqueK294.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK294.AA Pkinase_Tyr 8-129 43 1.2e-66 226.35 Pfam 130-253 (270) Show / Hide 
Range on Protein: 8-129
Range on HMM: 130-253/270
Sequence Identity: 43% (55 aa)

KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQAKK---IPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKP-FENSTNQESIR
|...||||||||.||..  ....||.|||..||.....|| .....   .||||.|||...|.|....|||||.| .|.|| ..| .| ... .|.| ..
KNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYE

LV-DSGYRLPPPPGCPKPMYKLMMQCW
.. ..|||.|.|..||...|.||.|||
YIYEDGYRMPCPENCPDEIYDLMKQCW
Kinase AqueK294.AA Eph 10-129 52 1.8e-61 205.17 In-house 126-247 (264) Show / Hide 
Range on Protein: 10-129
Range on HMM: 126-247/264
Sequence Identity: 52% (65 aa)

FVHRDLAARNILVSDEGTGICKIADFGMSRDLQDES----YYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLV
.||||||||||||. .   .||..|||.|| |.|..     | ..  ||||.||||||. |.|..||||||||| || |. | | .|. . .||. |  .
YVHRDLAARNILVNSN--LVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI

DSGYRLPPPPGCPKPMYKLMMQCW
. |||||||..||.....||..||
EQGYRLPPPMDCPEALHQLMLDCW
Kinase AqueK294.AA TK 8-129 29 1.2e-59 198.3 In-house 253-469 (486) Show / Hide 
Range on Protein: 8-129
Range on HMM: 253-469/486
Sequence Identity: 29% (63 aa)

K------KFVHRDLAARNILVSDEGT---------GICKIADFGMS--------RDL-QDESYYISQ------------------------AKKIPIKWT
|      .||||||||||.||.....          .|||||||.|        ||. .|. || ..                          |.||.|.
KNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWM

APEALH---------YKKYSSASDVWSYGAVMYEIWSLGYKPFEN-STN---------QESIRLVDSG--------------YRLPPPPGCP--------
|||.|          |.|....|||||.| .|.||...| .|.    .|         || .... .|              .|.|.||.||        
APECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH

------KPMYKLMMQCW
      . .| ||.|||
PPHCPPEEYYDLMQQCW
Kinase AqueK294.AA SFK-Src 10-129 50 7.5e-59 172.76 In-house 117-238 (259) Show / Hide 
Range on Protein: 10-129
Range on HMM: 117-238/259
Sequence Identity: 50% (63 aa)

FVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESY-YIS-QAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLVDS
||||||||||.|| |    .||..|||||| | ...  |   .  | |||||||||  . ..|  |||||.|  |.||  .| .|..  ||.| .. || 
FVHRDLAARNVLVGDN--NVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDR

--GYRLPPPPGCPKPMYKLMMQCW
  |||.| ||.||  .||.|..||
PEGYRMPCPPNCPDEYYKIMFDCW
Kinase AqueK294.AA Src 8-129 44 1.8e-55 186.87 In-house 116-238 (255) Show / Hide 
Range on Protein: 8-129
Range on HMM: 116-238/255
Sequence Identity: 44% (56 aa)

KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQ--DESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLV
....||||||||.||...   .||.||||  | ..  |. |  ..  |.|||||||||..| ...  |||||.|  ..|| . |  | .  ||.| .. |
MNYIHRDLAARNVLVGENN--VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQV

DSGYRLPPPPGCPKPMYK-LMMQCW
. |||.| |..||. .|. .|.|||
ERGYRMPCPHNCPDELYEQIMLQCW
Kinase AqueK294.AA UTK 7-130 42 8.4e-55 185.91 In-house 136-280 (296) Show / Hide 
Range on Protein: 7-130
Range on HMM: 136-280/296
Sequence Identity: 42% (62 aa)

GKKFVHRDLAARNILVSDEG-----TGICKIADFG---MSRDLQD--------ES-YYISQ-AKKIPIKWTAPEALHYK-KYSSASDVWSYGAVMYEIWS
...||||||||||.|| . .       .|||||||   |||....        || || .| ....||.|.||||| .  .....|||||.| |..|||.
SCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWT

LGYKPFENSTNQESIRLVDSG--YRLPPPPGCPKPMYKLMMQCWY
 | .|... .|.. .  |  |  ||.|.|..|| |.|.||..||.
WGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWH
Kinase AqueK294.AA SRM 8-129 46 3.4e-52 172.82 In-house 116-235 (253) Show / Hide 
Range on Protein: 8-129
Range on HMM: 116-235/253
Sequence Identity: 46% (57 aa)

KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLVDS
....||||||||.|| |. .  ||..|||. | . |  |  |   .||.|||||||. |  ||  |||||.|  ..|. . |  |..  || | .  .| 
QNYIHRDLAARNVLVGDNNL--CKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPGMTNHETFQQIDR

GYRLPPPPGCPKPMYKLMMQCW
|||.| |  ||   .|||..||
GYRMPCPAECPPEVHKLMLECW
Kinase AqueK294.AA Fer 7-129 37 9.8e-52 174.49 In-house 129-265 (283) Show / Hide 
Range on Protein: 7-129
Range on HMM: 129-265/283
Sequence Identity: 37% (51 aa)

GKKFVHRDLAARNILVSDEGTGI-CKIADFGMSRDLQDESYYIS---QAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFEN------S
.|. .|||.||||.|...... . |||.||||||.. |. |  .    |.|.||.|.|||.. .. ||...||||.| ...|| . |..|...       
SKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKM

TNQ--ESIRL-VDSGYRLPPPPGCPKPMYKLMM-QCW
||.  . ..  ...||..|.|...|......|| |||
TNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCW
Kinase AqueK294.AA Syk 7-129 47 3.7e-48 163.88 In-house 124-246 (257) Show / Hide 
Range on Protein: 7-129
Range on HMM: 124-246/257
Sequence Identity: 47% (59 aa)

GKKFVHRDLAARNILVSDEGTGICKIADFGMSRDL-QDESYYISQAK-KIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRL
.|.||||||||||.|  ..  .  || |||||. |  |..|| ..   | |.|| |||   | | |..|||||.|  | |  |.| ||    ..|| . .
EKHFVHRDLAARNVLLVNR--HYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKF

VDSGYRLPPPPGCPKPMYKLMMQCW
...| |.. |.|||. || || .||
IENGHRMNCPNGCPQEMYQLMNKCW
Kinase AqueK294.AA TK-Unique 6-129 40 1.4e-47 162.18 In-house 148-277 (294) Show / Hide 
Range on Protein: 6-129
Range on HMM: 148-277/294
Sequence Identity: 40% (54 aa)

QG--KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQAK--KIPIKWTAPEALH--YKKY-SSASDVWSYGAVMYEIWSLGYKPFENSTN
..  ||.|||||.|||.|...   ..|||.||||.||....  |... .  .|||.| |||.|   .. | .. |||||.| .|.|| .||  |. .  .
ASQRKKIVHRDLCARNVLLTE--DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPW

QESIRLVDSGYRLPPPPGC-PKPMYKLMMQCW
 . ....  |||.| |..| .. ||.|| .||
KDIMECIRDGYRMPQPEHCCSHEMYNLMKSCW
Kinase AqueK294.AA Tec 8-129 45 1.7e-46 160.45 In-house 116-235 (254) Show / Hide 
Range on Protein: 8-129
Range on HMM: 116-235/254
Sequence Identity: 45% (56 aa)

KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQAKKIPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLVDS
..|.|||||||| ||.|.  .. |..||||.|   |  |  |   | |.|| .|| .|| .||| ||||..|  | |..|.|  |.|| .| | .  |  
HCFIHRDLAARNCLVGDQ--CVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQ

GYRLPPPPGCPKPMYKLMMQCW
|.||  |  |.. .|. | .||
GHRLYRPHLCSMHIYQIMYHCW
TyrKc AqueK294.AA TyrKc 1-131 25 1.1e-15 31.16 SMART 19-265 (280) Show / Hide 
Range on Protein: 1-131
Range on HMM: 19-265/280
Sequence Identity: 25% (63 aa)

EWS------TCQ-----------------G----------------------------------------------------------------------
.|.      ...                 |                                                                      
TWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHS

KKFVHRDLAARNILVSDEGTGICKIADFGMSRDLQDE-------SYYISQ---AKK--IPIKWTAPEALHYKKYSSASDVWSYGAVMYEIWSLGYKPFEN
|...||||||||.||....  ..||.|||.|||. |.       .|| ..    .|  .||.|.|||.. |.|....|||||.| .|.|| ..| .| ..
KNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPG

-----STNQESIRLVDSGYRLPPPPG--------CPKPMYKLMMQCWYV
      .||| |..|..|||.|.||         ||. ||..| |||  
MIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE
Kinase AqueK294.AA Pkinase 8-84 28 3.1e-10 37.28 Pfam 127-204 (293) Show / Hide 
Range on Protein: 8-84
Range on HMM: 127-204/293
Sequence Identity: 28% (24 aa)

KKFVHRDLAARNILVSDEGTGIC----KIADFGMSRDLQDESYYISQAKKIP---IKWTAPEALH-YKKYSSASDVWSYGAVMYE
....||||   |||..   .| .    ||.||| .. ..   |  ..  . .   . . ||| .  ...|....|.||.| ..||
MGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYE
S_TKc AqueK294.AA S_TKc 1-130 14 0.000605 -119.07 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-130
Range on HMM: 19-231/231
Sequence Identity: 14% (35 aa)

EWST----------------------------------------------CQG-----------------------------------------KKFVHR
 .                                                | |                                         ....||
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHR

DLAARNILVSDEGTGICKIADFGMSRDLQDESYYISQAKKIPIKWTAPEALHYKKYSS-ASDVWSYGAVMYEIWSLGYKPFENSTNQESIRLVDSGYRLP
||   |||...      ||.|||..| |                . ||| |   .|.  ..|.|| | ..||  . || ||.  . |. ....       
DLKPENILLDE----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG------

PPPGC----------PK---PMYKLMM-------QCWY
.|...          |.      ...          | 
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF