Gene AqueK286 (A.queenslandica)

AqueK286

Species: A.queenslandica
Alias: AqueK286
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK286.AA Protein None 718 None Fasta, JSON
AqueK286.kin_dom Protein Kinase Domain None 93 None Fasta, JSON

Protein domain

Protein domains of AqueK286.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK286.AA Pkinase_Tyr 566-656 41 7.5e-37 125.44 Pfam 1-98 (270) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-98/270
Sequence Identity: 41% (41 aa)

IKVTDYLGSGQFGTVNKGIWT-TPTAGSVSVAIKTLNDNTSEDE--RVKFLQEAAIMGQF-HHPNVVKLHGVVT-IGHP--IMIVLKLISGGDLKEYL
|.    ||.|.||.| ||.|.  |  . . ||.|.|........  | .|..||.|| |. ||||.|.|.||.|  | |  |.||. .  .|||..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL
Kinase AqueK286.AA Eph 566-656 44 1.2e-32 106.85 In-house 1-95 (264) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-95/264
Sequence Identity: 44% (42 aa)

IKVTDYLGSGQFGTVNKGIWTTP-TAGSV---SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
||..  .|.|.|| | .|   .|  .  |    |||||| .  .| .|. || ||.||||| |||...| |||| . |.|||      | | ..|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFL
Kinase AqueK286.AA TK 566-656 28 4.5e-31 100.8 In-house 1-150 (486) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-150/486
Sequence Identity: 28% (42 aa)

IKVTDYLGSGQFG---TVNKGIWTT----------------------PTAGSVSVAIKTLN--DNTSEDERVK-----------FLQEAAIMGQFH----
|.. . ||.||||   .| ||.| .                      .. | . ||.|.|   |..|..|.             ||.||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVKLHGVVTIG------------HPIMIVLKLISGGD----LKEYL
 |||.|.|.||.| |            .|.|||. . ..||    |..||
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYL
Kinase AqueK286.AA UTK 566-656 35 5.5e-29 96.31 In-house 1-101 (296) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-101/296
Sequence Identity: 35% (36 aa)

IKVTDYLGSGQFGTVNKGIWTTPT--AGSVSVAIKTLN-DNTSEDERV---KFLQEAA---IMGQFH-HPNVVKLHGVVTIGHPIMIVLKLISGGDLKEY
..  . ||.|.||.|.|. .|...  .. . ||.|... . ....|.    .|. ||.   .|.||| ||||..| ||.| . |.|||. . ..|||  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

L
|
L
Kinase AqueK286.AA Fer 566-660 34 9.4e-28 91.67 In-house 1-104 (283) Show / Hide 
Range on Protein: 566-660
Range on HMM: 1-104/283
Sequence Identity: 34% (36 aa)

IKVTDYLGSGQFGTVNKG------IW-TTPTAGSVSVAIKTLNDN-TSEDERVKFLQEAAIMGQ-FHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
.. .. ||.| ||.| ||      .  .. .  .| |. |... . ...... .|..|| || . . ||||||..|| .  .|||||. ...||.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

NKFK
 | |
KKNK
Kinase AqueK286.AA SFK-Src 566-656 44 4.3e-27 76.84 In-house 1-85 (259) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-85/259
Sequence Identity: 44% (41 aa)

IKVTDYLGSGQFGTVNKGIWTTPTAGSVSVAIKTLND-NTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
|.    ||||||| | || |   |.    ||.|||    .|..|   |||||..| .  ||| ..|. | |.| || |.  |.  | |  ||
IRLEKKLGSGQFGDVWKGRWNNTTE----VAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYL
Kinase AqueK286.AA InsR 566-656 38 5.6e-25 80.75 In-house 1-95 (278) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-95/278
Sequence Identity: 38% (37 aa)

IKVTDYLGSGQFGTVNKG--IWTTPTAGSV--SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
|     .| | ||.|  |      |  ..    .||||.|.| |  ||. ||.|| .| .| . .||.| ||.. | | ..|  .   |||| ||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYL
Kinase AqueK286.AA RTKC 566-658 43 9.6e-24 75.14 In-house 1-94 (261) Show / Hide 
Range on Protein: 566-658
Range on HMM: 1-94/261
Sequence Identity: 43% (41 aa)

IKVTDYLGSGQFGTVNKGIWTTPT-AGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYLNK
... | || | || | |.    |  .    || | | .  .. .|   | |||.| || |||||.| |||| | || .||     |.|| || .
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMN
Kinase AqueK286.AA Src 566-656 41 9.8e-24 77.47 In-house 1-85 (255) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-85/255
Sequence Identity: 41% (38 aa)

IKVTDYLGSGQFGTVNKGIWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
||  . ||.|||| | .|.|     |.. ||.|||   |   .   ||||| || .. |...|.|. |.. . || ||  . | | | .||
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYL
Kinase AqueK286.AA ALK 566-656 38 6.4e-23 75.96 In-house 1-93 (273) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-93/273
Sequence Identity: 38% (36 aa)

IKVTDYLGSGQFGTVNKGIWTT--PTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
|.    || | || |  |  .     .    ||.|||    |...   |. ||.|||.| |.|||.. |.     | |||| ...|||.| .|
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFL
Kinase AqueK286.AA Ror 566-656 36 1e-21 78.44 In-house 1-93 (308) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-93/308
Sequence Identity: 36% (34 aa)

IKVTDYLGSGQFGTVNKGIWTTPT--AGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGGDLKEYL
...   || .||| | ||. . |       .|||||. .. |  ..  | ||. .| ..||||.|.| ||.|   |   .   .. ||| | |
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFL
Kinase AqueK286.AA TyrKc 566-702 16 1.9e-09 -69.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 566-702
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

IKVTDYLGSGQFGTVNKGIWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQF--HHPNVVKLHGVVTIG-------HPIMIVLKLISGGDLKEYL
|.  . ||.|.||.| ||.|.      . ||.|.|....    |  |..|| || ..  ||||.|.|.||.| .       .|.|||. . ..||||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NKFKP---------------------------------------SNP-----------------------DTY------NRP------------------
 | .|                                       .|                        |.|      ..                   
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

----------------------SFSD-----ISSS-----------LSSPDK---------------QLLMINKEDPV-----TVLGGAL
                        ..     .| .           .  |.                  ..  .|||      . .   .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK286.AA Pkinase 566-656 26 7.1e-08 28.92 Pfam 1-95 (293) Show / Hide 
Range on Protein: 566-656
Range on HMM: 1-95/293
Sequence Identity: 26% (26 aa)

IKVTDYLGSGQFGTVNKGIWTTPTAGSVS-VAIKTLN-DNTSEDERVKFLQ--EAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISGG----DLKEYL
...   .||| ||.| |...     |.   ||.|... .........  .   |..||  ..|||.|.|..... .  | .|. .  ||    ||..|.
YHIGRKIGSGSFGCVYKCHH----KGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI
Kinase AqueK286.AA S_TKc 566-715 13 1.2e-05 -94.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 566-715
Range on HMM: 1-231/231
Sequence Identity: 13% (35 aa)

IKVTDYLGSGQFGTVNKGIWTTPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLKLISG--GDLKEYLNKF----
 .. . .|.| ||.| |....        |||| ..         ....| .|. . ||||.|||..|    . . .|. ...|  |||..|. |     
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

---------------------------------KPSN----------------------------------PDT----------------YNRPSFSDIS
                                 ||.|                                   ..                . .| |.   
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---

SSLSSPDKQLLMINKEDPVTVLGGALE-------TSHSLYT-D-----LQYM
     ... . .|  ..    . . |.       |   . . .      ...
----QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK286.AA TK 669-679 45 0.038269 2.12 In-house 476-486 (486) Show / Hide 
Range on Protein: 669-679
Range on HMM: 476-486/486
Sequence Identity: 45% (5 aa)

RPSFSDISSSL
||.||.. . |
RPTFSQLHEQL
Kinase AqueK286.AA Eph 668-679 50 0.190594 0.46 In-house 253-264 (264) Show / Hide 
Range on Protein: 668-679
Range on HMM: 253-264/264
Sequence Identity: 50% (6 aa)

NRPSFSDISSSL
.|| |..| | |
HRPHFQQIVSIL
Kinase AqueK286.AA Pkinase_Tyr 668-679 50 0.899233 3.24 Pfam 259-270 (270) Show / Hide 
Range on Protein: 668-679
Range on HMM: 259-270/270
Sequence Identity: 50% (6 aa)

NRPSFSDISSSL
.||.||.| . |
DRPTFSEIHEQL