AqueK285

Species: A.queenslandica
Alias: AqueK285
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK285.AA Protein None 90 None Fasta, JSON
AqueK285.kin_dom Protein Kinase Domain None 89 None Fasta, JSON

Protein domain

Protein domains of AqueK285.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK285.AA Pkinase_Tyr 2-90 39 3.7e-42 143.4 Pfam 152-242 (270) Show / Hide
Range on Protein: 2-90
Range on HMM: 152-242/270
Sequence Identity: 39% (36 aa)

ISDFGMSRDLTEDEDYY-MAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKP-FDTLKNNETVKTV-ASGRRLSPSPGCP
|.|||..||. ...|||  ...|| .|.||.|||.|.  |....|||||.| .|.|| ..|..| .  ..|.| .. .  .|.|. . ..||
ICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCP

Kinase AqueK285.AA TK 2-90 23 1.6e-34 112.59 In-house 292-444 (486) Show / Hide
Range on Protein: 2-90
Range on HMM: 292-444/486
Sequence Identity: 23% (36 aa)

ISDFGMS--------RDLTEDEDYYMAGE-----------------------GGLIPVKWTAPESIKQHK---------YSSASDVWSYGCVMYEIWSLG
|.|||.|        ||. .|.||| ...                       || .|..|.|||... ..         ....|||||.|..|.||...|
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYG

RKPFDTLKNN----------ETVKTVASG--------------RRLSPSPGCP
..|.    .|          | .. . .|               |. . |.||
QEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCP

Kinase AqueK285.AA Syk 2-90 48 2.2e-32 108.8 In-house 147-235 (257) Show / Hide
Range on Protein: 2-90
Range on HMM: 147-235/257
Sequence Identity: 48% (43 aa)

ISDFGMSRDLTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASGRRLSPSPGCP
|||||||. |  |..|| |  .|  |||| |||.|   | |..|||||.|  | |  |.| ||    |. | .| . .| |..  .|||
ISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTMWEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCP

Kinase AqueK285.AA UTK 2-90 35 1.8e-31 104.89 In-house 166-268 (296) Show / Hide
Range on Protein: 2-90
Range on HMM: 166-268/296
Sequence Identity: 35% (37 aa)

ISDFG---MSRDLT-------EDED-YYMAGEGGLIPVKWTAPESIKQH-KYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASG--RRLSPSP
|.|||   |||..        ..|. |||| . . .|..|.|||.. .| .....|||||.| |..|||. ||.|.  . | .... |  |  .|. . .
IADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPW

GCP
.||
DCP

Kinase AqueK285.AA SFK-Src 2-90 43 2.3e-31 89.77 In-house 137-227 (259) Show / Hide
Range on Protein: 2-90
Range on HMM: 137-227/259
Sequence Identity: 43% (40 aa)

ISDFGMSRDLTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVAS--GRRLSPSPGCP
. |||||| | .|.  | | ||   |.||||||  .  ..|  |||||.|  |.||  .||.|.. . | | .. |    | |.   |.||
VGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCP

Kinase AqueK285.AA Trk 1-90 41 3.7e-31 102.8 In-house 157-247 (275) Show / Hide
Range on Protein: 1-90
Range on HMM: 157-247/275
Sequence Identity: 41% (38 aa)

QISDFGMSRDLTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASGRR-LSPSPGCP
.|.|||||||. .  |||  |  .  |. |  ||||  .|..  |||||.| || |. . |. |.. | |.| .  .  ||  |    .||
KIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCP

Kinase AqueK285.AA Eph 2-90 47 7.9e-30 97.28 In-house 146-236 (264) Show / Hide
Range on Protein: 2-90
Range on HMM: 146-236/264
Sequence Identity: 47% (44 aa)

ISDFGMSRDLTED---EDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASGRRLSPSPGCP
.||||.|| | .|   |. |    || ||..||||| |   |..||||||||| || |. | | .|.  . | . .| .  | || | ..||
VSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCP

Kinase AqueK285.AA CTKA 2-90 38 2.3e-27 88.91 In-house 172-262 (290) Show / Hide
Range on Protein: 2-90
Range on HMM: 172-262/290
Sequence Identity: 38% (35 aa)

ISDFGMSRDLTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASG--RRLSPSPGCP
|.||| .| |     ||.    ...|| | ||| ..  |.|.|||||..| ...|| | | ||.  .   | .. ..|.  ||| . . ||
IADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCP

Kinase AqueK285.AA Fer 2-90 31 2.5e-27 90.19 In-house 155-253 (283) Show / Hide
Range on Protein: 2-90
Range on HMM: 155-253/283
Sequence Identity: 31% (31 aa)

ISDFGMSRD-LTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDT----LKNNET----VKT-VASGRRLSPSPGCP
||||||||.  .. .||.|. .   .|..|.|||...   ||...||||.|....|| . | .|. .    .|....    .|  . .|... . ...|
ISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMP

Kinase AqueK285.AA Src 2-90 40 3.6e-26 85.86 In-house 138-226 (255) Show / Hide
Range on Protein: 2-90
Range on HMM: 138-226/255
Sequence Identity: 40% (36 aa)

ISDFGMSRDLTE-DEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASGRRLSPSPGCP
. |||  | |.. |.| | | .|  .|.|||||| |  ....  |||||.|  ..|| . || |    .| |... |  | |.   ..||
VADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCP

Kinase AqueK285.AA FAK 4-90 44 9.4e-26 83.13 In-house 167-252 (285) Show / Hide
Range on Protein: 4-90
Range on HMM: 167-252/285
Sequence Identity: 44% (39 aa)

DFGMSRDLTEDEDYYMAGEGGLIPVKWTAPESIKQHKYSSASDVWSYGCVMYEIWSLGRKPFDTLKNNETVKTVASGRRLSPSPGCP
|||.|| . .|..|| |   |  |.|| .||||    . .||||| .|  | || ..| |||  .|||. .  .  | ||   | ||
DFGLSR-WMHDHSYYKASPKGKLPIKWMSPESINFRRFTTASDVWMFGVCMWEILMYGVKPFQWVKNNDVIGRIENGERLPMPPNCP

Kinase AqueK285.AA TyrKc 2-90 14 2e-06 -117.98 SMART 1-280 (280) Show / Hide
Range on Protein: 2-90
Range on HMM: 1-280/280
Sequence Identity: 14% (40 aa)

I---------------------------------------------------------------------------------------------------
|                                                                                                   
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

-----------------------------------------SDFGMSRDLTED------EDYYMAGE--GGL--IPVKWTAPESIKQHKYSSASDVWSYG
                                         ||||.|||...|      .|||.. |  ||   .|..|.|||.|. .|....|||||.|
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

CVMYEIWSLGRKPFDT-----LKNNETVKTVASGRRLSPSPG------------------------------------CP
 .|.|| ..| .|        ..| | .. | .|.|. . |                                     | 
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK285.AA Pkinase 32-56 46 8e-06 21.61 Pfam 179-204 (293) Show / Hide
Range on Protein: 32-56
Range on HMM: 179-204/293
Sequence Identity: 46% (12 aa)

APESIK-QHKYSSASDVWSYGCVMYE
||| |. . .|....|.||.||..||
APEVIRGGQYYGPKVDMWSCGCILYE