Gene AqueK273 (A.queenslandica)

AqueK273

Species: A.queenslandica
Alias: AqueK273
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK273.AA Protein None 787 None Fasta, JSON
AqueK273.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of AqueK273.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK273.AA Pkinase_Tyr 488-578 42 1.1e-39 134.99 Pfam 1-98 (270) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-98/270
Sequence Identity: 42% (42 aa)

IKVTDYLGSGQFGTVNKGVWT-KPTAGSVSVAIKTLNDNTSEDE--RVKFLQEAAIMGQF-HHPNVVKLHGVVT-IGHP--IMIVLELISGGDLKEYL
|.    ||.|.||.| ||.|. .|  . . ||.|.|........  | .|..||.|| |. ||||.|.|.||.|  | |  |.||.|.  .|||..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL
Kinase AqueK273.AA Eph 488-578 45 2.3e-34 112.73 In-house 1-95 (264) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-95/264
Sequence Identity: 45% (43 aa)

IKVTDYLGSGQFGTVNKGVWTKP-TAGSV---SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
||..  .|.|.|| | .|   .|  .  |    |||||| .  .| .|. || ||.||||| |||...| |||| . |.||| |    | | ..|
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFL
Kinase AqueK273.AA TK 488-578 28 1.1e-32 106.33 In-house 1-150 (486) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-150/486
Sequence Identity: 28% (43 aa)

IKVTDYLGSGQFG---TVNKGVWTK----------------------PTAGSVSVAIKTLN--DNTSEDERVK-----------FLQEAAIMGQFH----
|.. . ||.||||   .| || |                        .. | . ||.|.|   |..|..|.             ||.||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVKLHGVVTIG------------HPIMIVLELISGGD----LKEYL
 |||.|.|.||.| |            .|.|||.|. ..||    |..||
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYL
Kinase AqueK273.AA Fer 488-578 35 9.5e-31 102.02 In-house 1-100 (283) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-100/283
Sequence Identity: 35% (35 aa)

IKVTDYLGSGQFGTVNKG--VWTKPT-AGSV----SVAIKTLNDN-TSEDERVKFLQEAAIMGQ-FHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
.. .. ||.| ||.| ||  . .     ..|     |. |... . ...... .|..|| || . . ||||||..|| .  .|||||.|...||.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL
Kinase AqueK273.AA SFK-Src 488-578 45 7.3e-30 85.21 In-house 1-85 (259) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-85/259
Sequence Identity: 45% (42 aa)

IKVTDYLGSGQFGTVNKGVWTKPTAGSVSVAIKTLND-NTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
|.    ||||||| | ||.| . |.    ||.|||    .|..|   |||||..| .  ||| ..|. | |.| || |. ||.  | |  ||
IRLEKKLGSGQFGDVWKGRWNNTTE----VAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYL
Kinase AqueK273.AA UTK 488-578 36 1.4e-29 98.32 In-house 1-101 (296) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-101/296
Sequence Identity: 36% (37 aa)

IKVTDYLGSGQFGTVNKGVWTKPT--AGSVSVAIKTLN-DNTSEDERV---KFLQEAA---IMGQFH-HPNVVKLHGVVTIGHPIMIVLELISGGDLKEY
..  . ||.|.||.|.|. .|...  .. . ||.|... . ....|.    .|. ||.   .|.||| ||||..| ||.| . |.|||.|. ..|||  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

L
|
L
Kinase AqueK273.AA InsR 488-578 40 8.9e-27 86.88 In-house 1-95 (278) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-95/278
Sequence Identity: 40% (38 aa)

IKVTDYLGSGQFGTVNKG--VWTKPTAGSV--SVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
|     .| | ||.|  |      |  ..    .||||.|.| |  ||. ||.|| .| .| . .||.| ||.. | | ..| |.   |||| ||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYL
Kinase AqueK273.AA Src 488-578 42 5.5e-25 81.78 In-house 1-85 (255) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-85/255
Sequence Identity: 42% (39 aa)

IKVTDYLGSGQFGTVNKGVWTKPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
||  . ||.|||| | .|.|     |.. ||.|||   |   .   ||||| || .. |...|.|. |.. . || || |. | | | .||
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYL
Kinase AqueK273.AA RTKC 488-578 45 8e-25 78.75 In-house 1-92 (261) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-92/261
Sequence Identity: 45% (42 aa)

IKVTDYLGSGQFGTVNKGVWTKPT-AGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
... | || | || | |.    |  .    || | | .  .. .|   | |||.| || |||||.| |||| | || .|||    |.|| ||
LTLLDELGRGAFGIVYKALLEEPGGMPGYLVACKSLHHTAMDNDRQELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYL
Kinase AqueK273.AA ALK 488-578 39 1e-24 82.24 In-house 1-93 (273) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-93/273
Sequence Identity: 39% (37 aa)

IKVTDYLGSGQFGTVNKGVWTK--PTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGGDLKEYL
|.    || | || |  |  .     .    ||.|||    |...   |. ||.|||.| |.|||.. |.     | |||||...|||.| .|
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFL
Kinase AqueK273.AA Ack 488-578 38 3.6e-24 78.42 In-house 1-93 (266) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-93/266
Sequence Identity: 38% (36 aa)

IKVTDYLGSGQFGTVNKGVWTKPTAGSVSVAIKTLNDN--TSEDERVKFLQEAAIMGQFHHPNVVKLHGVVTIGHPI-MIVLELISGGDLKEYL
|..   ||.| || | .|.|| |   ...||.| | .   ..  .   ||.|.||| .  ||..|.|.|||  . |  | | ||  .| | . |
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVV-LDQPMLMMVTELAPCGSLLDCL
Kinase AqueK273.AA Pkinase 488-578 26 2.3e-10 37.74 Pfam 1-95 (293) Show / Hide 
Range on Protein: 488-578
Range on HMM: 1-95/293
Sequence Identity: 26% (26 aa)

IKVTDYLGSGQFGTVNKGVWTKPTAGSVSVAIKTLN-DNTSEDERVKFLQ--EAAIMGQFHHPNVVKLHGVVTIGHPIMIVLELISGG----DLKEYL
...   .||| ||.| |... .    .  ||.|... .........  .   |..||  ..|||.|.|..... .  | .|.|.  ||    ||..|.
YHIGRKIGSGSFGCVYKCHHKG---TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI
Kinase AqueK273.AA TyrKc 488-579 13 1e-05 -130.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 488-579
Range on HMM: 1-280/280
Sequence Identity: 13% (40 aa)

IKVTDYLGSGQFGTVNKGVWTKPTAGSVSVAIKTLNDNTSEDERVKFLQEAAIMGQF--HHPNVVKLHGVVTIG-------HPIMIVLELISGGDLKEYL
|.  . ||.|.||.| ||.|.      . ||.|.|....    |  |..|| || ..  ||||.|.|.||.| .       .|.|||.|. ..||||.||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

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RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

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TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK273.AA TK 732-748 41 0.004211 5.39 In-house 470-486 (486) Show / Hide 
Range on Protein: 732-748
Range on HMM: 470-486/486
Sequence Identity: 41% (7 aa)

NPDTHDRPSFSDISSSL
..|  |||.||.. . |
HYDPEDRPTFSQLHEQL
Kinase AqueK273.AA RTKC 734-748 46 0.013932 4.2 In-house 247-261 (261) Show / Hide 
Range on Protein: 734-748
Range on HMM: 247-261/261
Sequence Identity: 46% (7 aa)

DTHDRPSFSDISSSL
. ||||.||..   |
TPHDRPTFSEVVHWL
Kinase AqueK273.AA Ack 737-748 58 0.023195 3.78 In-house 255-266 (266) Show / Hide 
Range on Protein: 737-748
Range on HMM: 255-266/266
Sequence Identity: 58% (7 aa)

DRPSFSDISSSL
|||.||.|   |
DRPTFSAIRDQL
Kinase AqueK273.AA Eph 734-748 46 0.041461 2.72 In-house 250-264 (264) Show / Hide 
Range on Protein: 734-748
Range on HMM: 250-264/264
Sequence Identity: 46% (7 aa)

DTHDRPSFSDISSSL
| ..|| |..| | |
DRNHRPHFQQIVSIL
Kinase AqueK273.AA UTK 732-748 29 0.118635 1.43 In-house 280-296 (296) Show / Hide 
Range on Protein: 732-748
Range on HMM: 280-296/296
Sequence Identity: 29% (5 aa)

NPDTHDRPSFSDISSSL
..|  .||.| |. . .
HYDPQERPDFEDLVQQM
Kinase AqueK273.AA Pkinase_Tyr 737-748 58 0.232436 5.23 Pfam 259-270 (270) Show / Hide 
Range on Protein: 737-748
Range on HMM: 259-270/270
Sequence Identity: 58% (7 aa)

DRPSFSDISSSL
|||.||.| . |
DRPTFSEIHEQL