Gene AqueK266 (A.queenslandica)

AqueK266

Species: A.queenslandica
Alias: AqueK266
External Links:
Annotation:

Classification

Group: TK
Family: EGFR

Sequence

Name Sequence Type Origin Length Description Download
AqueK266.AA Protein None 842 None Fasta, JSON
AqueK266.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of AqueK266.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Recep_L_domain AqueK266.AA Recep_L_domain 48-165 27 3e-17 59.69 Pfam 1-121 (121) Show / Hide 
Range on Protein: 48-165
Range on HMM: 1-121/121
Sequence Identity: 27% (36 aa)

GCRYIEDNIVIRTGSGLVDISQPLVEANFSFLYYVIEISGYLELNNI-PSIERLSLPRLRLIRGRNLRSG-RYSLLVS--GR--IETLYMPRLTEISR--
.|. |. |..|   ..  .      | ..||.  . ||.|||....  .      .|.|| ||||.|  . .|.| .       .. |.|. |..|.|  
NCTVIYGNLEITWRDEHNE-----LEEDLSFFPNIREITGYLLIYRTYNLKNLSFFPNLRIIRGRQLFHDDNYALYIYDNPNMGLQELWMWNLKNITRKN

GDVLLGSSSLNS--YLCNTRS-INWTDIA
|.|     . |    ||.|.. |.| .| 
GGVYI---HNNPHPKLCYTHTEIMWWMIY
Furin-like AqueK266.AA Furin-like 187-335 27 1.1e-24 81.5 Pfam 3-182 (182) Show / Hide 
Range on Protein: 187-335
Range on HMM: 3-182/182
Sequence Identity: 27% (49 aa)

DCN------ALGCSSGF-----------CWCNDTDCCQT---LSFNCNCNNSRCFRDGQNIHCCHPECVAGCSGYD-NSQCFACKNVLNVGACQERCPNQ
.|       . .|..             ||  . . |||     ....|...||.    . .|||..| .||.| . .. |.||... . |.| ..||  
ECPDVCPGTCEPCHPCCKTTINGHYGYRCWGPNPQHCQTLTKKVCPEQCKHRRCTG-PKPGECCHEQCLGGCTGPNNDTDCVACRHFYHNGTCVDQCPPM

FIINPFTRTFIPNPEFKLEA-QPLCV--SSCP--------DMLFQVDTQCVKNCPSNYMPVANNGTMRCVLCNDTCPKKCT
.| || |   .|||. . .     ||  ..||          .   ...|.  |||.|. . .|.|| |. |. .||| |.
MIYNPTTFQMEPNPDGTYQFEGWRCVTFKECPKLSHNPDCNYYVIHNGECMRECPSGYTENEENNTMMCEPCEGPCPKVCY
FU AqueK266.AA FU 226-268 33 5.3e-09 37.15 SMART 1-48 (48) Show / Hide 
Range on Protein: 226-268
Range on HMM: 1-48/48
Sequence Identity: 33% (16 aa)

NIHC--CHPECVAGCSGYDNSQCFACKNVLNV---GACQERCPNQFII
. .|  |||||  ||.| .. || .|.. .     |.| . || ..  
DGVCKPCHPECATGCWGPGPDQCTSCPHGYYLHHNGTCVSQCPPGYYP
Recep_L_domain AqueK266.AA Recep_L_domain 349-469 22 2e-10 36.76 Pfam 1-121 (121) Show / Hide 
Range on Protein: 349-469
Range on HMM: 1-121/121
Sequence Identity: 22% (30 aa)

GCTVITTDLRILSVPVNVNLSI-LNDLKDIREIRGSLDISGF-NKETFPYLSNLKTVGNDSSQVLSQSCNGSSDSIQFSIIIA-NTD--LVSIDLSSLEA
.||||  .|.|...  . .|.  |. .. ||||.|.| | .  |   .  ..||...  .. .             .....|  | .  | .... .|. 
NCTVIYGNLEITWRDEHNELEEDLSFFPNIREITGYLLIYRTYNLKNLSFFPNLRIIRGRQLFHD----------DNYALYIYDNPNMGLQELWMWNLKN

VIN--GGIQLENNP--SLCYLGN-LSYYLAN
...  ||.  .|||   |||.   .  .. .
ITRKNGGVYIHNNPHPKLCYTHTEIMWWMIY
FU AqueK266.AA FU 484-537 26 4e-06 27.75 SMART 1-48 (48) Show / Hide 
Range on Protein: 484-537
Range on HMM: 1-48/48
Sequence Identity: 26% (15 aa)

IDECVEMNMTCHSQCSSASGWCWGPNDTQCVTCTNFSFN---GQCVPDCHNFDAHGI
 ..|    . ||..|..    ||||...||..| .. .    |.||..|   . .  
DGVC----KPCHPECAT---GCWGPGPDQCTSCPHGYYLHHNGTCVSQCP--PGYYP
Furin-like AqueK266.AA Furin-like 494-529 54 0.0013 12.46 Pfam 65-98 (182) Show / Hide 
Range on Protein: 494-529
Range on HMM: 65-98/182
Sequence Identity: 54% (20 aa)

CHSQCSSASGWCWGPN-DTQCVTCTNFSFNGQCVPDC
||.||  . | | ||| || || | .|..||.||. |
CHEQC--LGG-CTGPNNDTDCVACRHFYHNGTCVDQC
FU AqueK266.AA FU 581-639 31 0.001047 19.56 SMART 1-48 (48) Show / Hide 
Range on Protein: 581-639
Range on HMM: 1-48/48
Sequence Identity: 31% (19 aa)

SGECLPCFNGCTLGNGCAGPGKTFNDSNGCSAC--DTILLNLNGEQIKCQRNVTCPSGYYR
.|.| ||  .|    || |||      . |..|     |...     .|    .||.|||.
DGVCKPCHPECAT--GCWGPG-----PDQCTSCPHGYYLHHN----GTCVS--QCPPGYYP
Kinase AqueK266.AA TK 653-670 44 1.2e-05 14.11 In-house 469-486 (486) Show / Hide 
Range on Protein: 653-670
Range on HMM: 469-486/486
Sequence Identity: 44% (8 aa)

WELEPERRPSFEDLVYQF
|...||.||.|..|. |.
WHYDPEDRPTFSQLHEQL
Kinase AqueK266.AA RTKB 646-670 36 1.3e-05 14.86 In-house 240-264 (264) Show / Hide 
Range on Protein: 646-670
Range on HMM: 240-264/264
Sequence Identity: 36% (9 aa)

RGIFLTGWELEPERRPSFEDLVYQF
..|    | .|.. ||.|. ||  |
DHIMQMCWQMEAQHRPDFDELVDAF
Kinase AqueK266.AA Src 648-670 43 2.9e-05 13.77 In-house 233-255 (255) Show / Hide 
Range on Protein: 648-670
Range on HMM: 233-255/255
Sequence Identity: 43% (10 aa)

IFLTGWELEPERRPSFEDLVYQF
|.|  |. .||.|| || |   .
IMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK266.AA UTK 653-670 55 3e-05 13.91 In-house 279-296 (296) Show / Hide 
Range on Protein: 653-670
Range on HMM: 279-296/296
Sequence Identity: 55% (10 aa)

WELEPERRPSFEDLVYQF
|. .|..||.||||| |.
WHYDPQERPDFEDLVQQM
Kinase AqueK266.AA RTKC 653-670 33 3.5e-05 12.92 In-house 244-261 (261) Show / Hide 
Range on Protein: 653-670
Range on HMM: 244-261/261
Sequence Identity: 33% (6 aa)

WELEPERRPSFEDLVYQF
| . |. ||.|...| ..
WMHTPHDRPTFSEVVHWL
Kinase AqueK266.AA SFK-Abl 648-670 43 5.5e-05 11.94 In-house 229-251 (251) Show / Hide 
Range on Protein: 648-670
Range on HMM: 229-251/251
Sequence Identity: 43% (10 aa)

IFLTGWELEPERRPSFEDLVYQF
| .  |...|. |||| ||  | 
IMTQCWDVNPDERPSFHDLQHQL
Kinase AqueK266.AA MLK 653-670 33 6e-05 12.05 In-house 263-280 (280) Show / Hide 
Range on Protein: 653-670
Range on HMM: 263-280/280
Sequence Identity: 33% (6 aa)

WELEPERRPSFEDLVYQF
|...| .||.|. .. |.
WNQDPHKRPKFSEILQQL
Kinase AqueK266.AA Csk 653-670 38 6.9e-05 12.66 In-house 234-251 (251) Show / Hide 
Range on Protein: 653-670
Range on HMM: 234-251/251
Sequence Identity: 38% (7 aa)

WELEPERRPSFEDLVYQF
|.|.| .||.|. .. | 
WHLNPAKRPTFRQVREQL
Kinase AqueK266.AA TKL-Sp1 656-670 66 0.000162 9.57 In-house 249-263 (263) Show / Hide 
Range on Protein: 656-670
Range on HMM: 249-263/263
Sequence Identity: 66% (10 aa)

EPERRPSFEDLVYQF
.||.||| |||  ||
KPEKRPSAEDLLDQF
Kinase AqueK266.AA PDGFR 653-670 38 0.000184 9.83 In-house 341-358 (358) Show / Hide 
Range on Protein: 653-670
Range on HMM: 341-358/358
Sequence Identity: 38% (7 aa)

WELEPERRPSFEDLVYQF
|...||.||.|. |.   
WDFDPEKRPTFQQLCQFL