Gene AqueK262 (A.queenslandica)

AqueK262

Species: A.queenslandica
Alias: AqueK262
External Links:
Annotation:

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
AqueK262.AA Protein None 845 None Fasta, JSON
AqueK262.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of AqueK262.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IG AqueK262.AA IG 31-139 15 4.1e-05 24.22 SMART 1-58 (58) Show / Hide 
Range on Protein: 31-139
Range on HMM: 1-58/58
Sequence Identity: 15% (18 aa)

MKPVYTFGSNTTSLPIIVSMVCMVNQSIDQVELRWIHDGITYSSTENNSSGRLSILNTTSSNDTSFTTTLTILPAMYTDN---GTYYCQVRDKGNSSSNW
 . |.     | .|.  ||            ...|                                  ||| .. . |    ||||||..        .
PP-VTVKEGETVTLTC-VS------------QIWWY---------------------------------LTI-NVQPEDSQQHGTYYCQAT--------H

TSART--NLHLLVH
 ..    . .| |.
GQYWSIQGTTLTVQ
V-set AqueK262.AA V-set 71-138 23 9e-05 18.29 Pfam 70-128 (128) Show / Hide 
Range on Protein: 71-138
Range on HMM: 70-128/128
Sequence Identity: 23% (16 aa)

TYSSTENNSSGRLSILNTTSSNDTSFTTTLTILPAMYTDNGTYYCQVRDKGNSSSNWTSARTNLHLLV
... ...  .|| .. ...|    . . .|||  .   |.|||||.| .      |  .  .  .| |
GHGYYYPRFKGRVTFSGNPS----KNDFSLTISNLQPSDSGTYYCAVWNC-----NEDYFGHGTRLTV
IG AqueK262.AA IG 145-246 14 2e-06 28.69 SMART 1-58 (58) Show / Hide 
Range on Protein: 145-246
Range on HMM: 1-58/58
Sequence Identity: 14% (15 aa)

PTVNATTSSPAAELSCDMAGYVPPQSSLHWYRNGTRLTNTGRYSIVYRDGWRRAQKESKDGTSSSVLGVLVISSPTVQDS---GQYQCRIEGYCHLTR--
|          ..|.|  .       ...||                                      |.| . ...||   | |.|. . .   .   
PP-VTVKEGETVTLTC-VS-------QIWWY--------------------------------------LTI-NVQPEDSQQHGTYYCQAT-HGQYWSIQ

SVQLTVK
...|||.
GTTLTVQ
IGv AqueK262.AA IGv 155-231 20 0.000253 14.25 SMART 1-76 (76) Show / Hide 
Range on Protein: 155-231
Range on HMM: 1-76/76
Sequence Identity: 20% (19 aa)

AAELSCDMAGYVPPQSSLHWYRN-------GTRLTNTGRYSIVYRDGWRRAQKESKDGTSSSVLG---------VLVISSPTVQDSGQYQCRI
 ..|||   |.      .||||        | .|   |.              ..|.  ..|             |..|. .. |.| | | .
SVTLSCKFSGFTF---YMHWYRQPPDSTPKGKGLEWMGY--------------SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
IGc2 AqueK262.AA IGc2 151-236 19 0.000507 13.44 SMART 1-56 (56) Show / Hide 
Range on Protein: 151-236
Range on HMM: 1-56/56
Sequence Identity: 19% (17 aa)

TSSPAAELSCDMAGYVPPQSSLHWYRNGTRLTNTGRYSIVYRDGWRRAQKESKDGTSSSVLGVLVISSPTVQDSGQYQCRIEGYCH
 .  ...| |. .|.  |.   |||. |..|                              . | |.. |. ||| |.|. ..  .
HEGQSVTLTCPATGNPDPN--IHWYK-GQPLP---------------------------WNWTLTIKNVTPEDSGYYTCYARNPWG
V-set AqueK262.AA V-set 156-245 19 0.353543 5.89 Pfam 24-128 (128) Show / Hide 
Range on Protein: 156-245
Range on HMM: 24-128/128
Sequence Identity: 19% (21 aa)

AELSCDMA-GYVP--PQSSLHWYRNGTRLTNTGRYSIVYRDGWRRA------QKESKDGTSSSVLGV-----LVISSPTVQDSGQYQCRIEG--YCHLTR
..|.|    .| .  . ....|||   .. .. .. | |  .. .       . . |. .. |. .      | ||. .. ||| | | . .  .     
VTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDYFGH

SVQLTV
...|||
GTRLTV
TyrKc AqueK262.AA TyrKc 554-836 36 8.20000000001e-118 398.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-280/280
Sequence Identity: 36% (115 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRL--NHDNVVRLLAVCTV--------GEHFIM
.  ..|||.|.||.| ... .                   | ||.|.|| .|    .|.| .| . |..|  .|.|.|||..|||         . ..| 
ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

MEYMENGDLNQFLQKHTLVPDTVTGLGDWEITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYES-------AYYRV-
||||..|||...|.||              ...  ||.. .||..|| || |....|||||.||||||....|||||||.|| .|.         |||. 
MEYMPHGDLKDYLRKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKK

---QGTLVLPIRWMACETF-YGKFSVKSDTWAFGVTLWEVYTLAMCDPYDE----MSDEEVIQDAIRGPNRKLLPKPEA--------CPREVYDVMLRCW
   .|  .||||||| |.. ||||. ||| |.|||..||..|. .  ....    ||..|||..  .|   . .|.|.         || |.|..|..||
EHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG---YRMPQPPNDYPMSFVCCPDEMYQIMKQCW

VHDPAMRADFGEIYSRL
 .||..|  | ||....
HEDPEDRPTFSEIHECF
Pkinase_Tyr AqueK262.AA Pkinase_Tyr 554-836 40 2e-109 371.23 Pfam 1-270 (270) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-270/270
Sequence Identity: 40% (119 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGL--LEAFDKEVKFMSRL-NHDNVVRLLAVCT-VGEH---FIMMEY
.. ..||| |.||.| ... .              . .. | ||.|.|| .|      .|.| .|.| |. | .|.|.|||..|||  ||.   .| |||
ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

MENGDLNQFLQKHTLVPDTVTGLGDWEITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYESAYY-RVQGTLVLPIRW
|..|||  .|.||          ..  .|.  || . .||..|| || |....|||||.|||||.....|||.|||..| .|.  || |..|   |||.|
MPHGDLLDYLRKHR--------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKW

MACE-TFYGKFSVKSDTWAFGVTLWEVYTLAMCDP-YDEMSDEEVIQDA-IRGPNRKLLPKPEACPREVYDVMLRCWVHDPAMRADFGEIYSRL
|| |  .||||..||| |.|||..||..|. .  | | .||.|||..    .   .  .|.|| || |.||.|..|| .||..|  | ||...|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYED---GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK262.AA TK 554-836 24 1.4e-102 344.74 In-house 1-486 (486) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-486/486
Sequence Identity: 24% (121 aa)

VIEIRKLGNGQFG---QVILARTRHLSLVDM---------KLSETLTDRSQSILVAIKKLKTNAETGLLEAFD-------------KEVKFMSRLN----
.. ..||| ||||   .| ... | ..  ..         .|      . . . ||.| ||  ...   | ||             .|.  |. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNVVRLLAVCTVGE-------------HFIMMEYMENGD----LNQFLQKHT----------------------------------------------
 |.|.|||..||| ||               |.||||..||    | ..|.|.                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------LVPDTVTGLGDWE------------ITPIILLYIGVQISSGMHYLGSR------RFVHRDLATRNCLVGKDFI-----------VKISDFGMS-
      ..|...|    .             .|.  || . .||..|| || |.      .|||||||.||||||.. .           .||.|||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RRLYE------------------------SAYYRVQGTLVLPIRWMACETFY----------GKFSVKSDTWAFGVTLWEVYTLAMCDPYDEM
       |..|.                        ..||| |    ||||||| |..           |||. ||| |.|||..||..|..   .| .|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SD---------EEVIQDAIRG-----------PNRKLLPKPEACP--------------REVYDVMLRCWVHDPAMRADFGEIYSRL
|.         .||..   ||            .|  .|.|. ||               |.||.|..|| .||. | .| .....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK262.AA DDR 554-836 42 5e-100 338.62 In-house 1-306 (306) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-306/306
Sequence Identity: 42% (131 aa)

VIEIRKLGNGQFGQVILARTRHLS-LVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRLN-HDNVVRLLAVCTVGEHFIM-MEYMEN-
 |   |.| |||| | |  .  .  ...         . . .||| |.|.  |   .  .| ||.| ||..  | |.|||..|||. |   | |||||| 
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCD-VHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENL

GDLNQFLQKHTLVPDTVTGL-GDWE------ITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFG--MSRRLYESAYYRVQG---
||||||...| .      .. .| .      |    ..||. || ||| || | .|||||||||||||||.. .|| |||  ||| || . ||||.|   
GDLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTG

--TLVLPIRWMACET-FYGKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIR----GPNRKLLPKPEACPREVY-DVMLRCWVHDPAMRADF
    ..|||||| |    |||. ||| ||||||.||. ...   || ...|| ||  |      ...  .||.| .||.|.| . |.|||  |.  |  |
RQRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSF

GEIYSRL
 ||   |
EEIHKFL
Kinase AqueK262.AA Trk 554-836 38 1e-91 311.0 In-house 1-275 (275) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-275/275
Sequence Identity: 38% (112 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRLNHDNVVRLLAVCTVGEHFIMM-EYMENGDL
.. .. || | ||.|.||   .|.  . |           ..||.| ||  .|    . | .| . .  | | ..|..  ||| .. ..|  |||..|||
IVLKWELGEGAFGKVFLAECYNLCPEQDK-----------MMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDL

NQFLQKHTLVPDTVTGLGD----WEITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYE-SAYYRVQGTLVLPIRWMA
|..|. |  . .  ..  .     . |   .|.|  || ||| |. |  |||||.||||||||.. ||||.||||||..|. . |||| .   |||||| 
NKYLRQHGPDAMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMP

CET-FYGKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRGPNRKL-LPKPEACPREVYDVMLRCWVHDPAMRADFGEIYSRL
 |   | ||.. || | |||..||..|     |.. .|  |||.    |   .. | .|..||.||||.|| ||  .| .|    .|. ..
PESIMYRKFTYESDVWSFGVVMWECFTYGK-QPWYQLSNHEVIECIHQG---RHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase AqueK262.AA UTK 554-836 34 2.2e-77 263.38 In-house 1-296 (296) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-296/296
Sequence Identity: 34% (108 aa)

VIEIRKLGNGQFGQVILARTRH----LSLVDMKLSETLTDRSQSILVAIKKLKTNAETG----LLEAFDKEVKFMSRLN-HDNVVRLLAVCTVGEHFIM-
|.  |.|| |.||.| .|| ..      ..|... .             .. .. ....    ..||   |. .|.... | ||.||..||| .| ... 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ----------HHADAQQEPEPYPDFMEEAR--ELQMMKQFHWHPNVLRLVGVCTQEEPWMIV

MEYMENGDLNQFLQKHTLVPDTVTGLGDWEITPII-LLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKD-------FIVKISDFG---MSRRLY----
.|||||||| ..|..|.  |.     .. ..     .|.  ..|..||.|| |..||||||| |||||...        ..||.|||   ||||..    
TEYMENGDLRSYLRRHRPTPP-----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHF

-----ESAYYRVQGTLVLPIRWMACETFYGK--FSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRGPNRKLLPKPEACPREVYDVMLRCWVH
     || ||. |.   .|||||| | ..    |. ||| |.|||..||..| .   || .||...|..   .| .| ..|.|..||..||..|.|||  
SNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRL-PYPGMSNMQVWHQVCNG-GRYRMPCPWDCPHPVYRLMHRCWHY

DPAMRADFGEIYSRL
||..| || ......
DPQERPDFEDLVQQM
Kinase AqueK262.AA TK-Unique 554-836 32 1.5e-75 257.3 In-house 1-294 (294) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-294/294
Sequence Identity: 32% (100 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRLN-HDNVVRLLAVCT-VG-EHFIMMEYMENG
.   ...| |.||||. .  . ..          ..... . ||.|.|| ||      .| || ..|. |  | |.|..| .||  .  ..|.|||...|
LEVGDVIGEGAFGQVWRGEVWGIW----------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

DLNQFLQKHT-------------LVPDTVTGLGDWE-ITPIILLYIGVQISSGMHYLGS--RRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYESAYYR
.|  .|..                 .....     | |.|  |. ...|| .|| || |  ...|||||..||.|.. |...||.||||.|..|    | 
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS

VQGT-LVLPIRWMACETFY---GKF-SVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRGPNRKLLPKPEAC-PREVYDVMLRCWVHDPAMRAD
 ...   .|||||| | ..   | . . ||| |.|||..||. ||    || .|.... |...||  . . .|.|| | ..|.| .| .|| ..| .| .
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKD-IMECIR--DGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPS

FGEIYSRL
| .| .||
FRQIKHRL
Kinase AqueK262.AA Musk 554-836 38 1e-74 246.25 In-house 1-282 (282) Show / Hide 
Range on Protein: 554-836
Range on HMM: 1-282/282
Sequence Identity: 38% (114 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRLNHDNVVRLLAVCTVGEHF-IMMEYMENGDL
.| .| .| | || |  ||   |          . .  . ..||.| || .|.  . . |. |   | .  | |.|.|| || ||     ..|||  |||
IIYVRDIGEGAFGRVFQARAPGL----------VPYEEE-TMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDL

NQFLQK---HTLVPDTVTGL---------GDWEITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYESAYYRVQGTLV
| ||.    |.    |   .         |  .   . .| .  ||  || ||  ..||||||||||||..    |||.|||.||. |   ||. ..   
NEFLHSCSPHRTCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDH

LPIRWMACET-FYGKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRGPNRKLLPKPEACPREVYDVMLRCWVHDPAMRADFGEIYSRL
 |||||. |  .| .|.. || ||.|| |||..  |   ||  |. ||||   ||  |.  |  || || .|| .| |||   || |  | .|   .
IPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYAL-QPYYGMTHEEVIY-YIRQGNI--LSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK262.AA Ror 592-836 45 1.3e-73 250.86 In-house 28-275 (308) Show / Hide 
Range on Protein: 592-836
Range on HMM: 28-275/308
Sequence Identity: 45% (115 aa)

QSILVAIKKLKTNAETGLLEAFDKEVKFMSRLNHDNVVRLLAVCTVGEHFIMM-EYMENGDLNQFLQKHTLVP--DTVTGLGDWEITPIIL-----LYIG
. ..||||..| .|.  . . | .|.. |..|.| |.| || |||  .   |  ||| .|||  ||  .  .|  |   . .|   . . |     |.| 
HCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMR--SPHSDHGCSSDDDRMVKSSLDHPDFLHIA

VQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYESAYYRVQGTLVLPIRWMACET-FYGKFSVKSDTWAFGVTLWEVYTLAMCDPYDE
.||..|| || |. |||||||.||||||    ||||||| .|  | | |||.|.  ..|||||. |   |||||. || | |||.|||..   |  ||  
IQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSEDSDIWSFGVVLWEIWSYGM-QPYYG

MSDEEVIQDAIRGPNRKLLPKPEACPREVYDVMLRCWVHDPAMRADFGEIYSRL
 |  ||| . ||  || ||| |. ||  .|  |  ||   |. |  | .| |||
YSNQEVI-EMIR--NRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHSRL
Kinase AqueK262.AA Src 593-836 36 2.8e-65 220.74 In-house 23-255 (255) Show / Hide 
Range on Protein: 593-836
Range on HMM: 23-255/255
Sequence Identity: 36% (92 aa)

SILVAIKKLKTNAETGLLEAFDKEVKFMSRLNHDNVVRLLAVCTVGE-HFIMMEYMENGDLNQFLQKHTLVPDTVTGLGDWEITPIILLYIGVQISSGMH
.. ||.| ||        ||| .| . |  | |...|.|.|||. .|  .|  |||..| | ..|.|        .| |  ..   .|.... |...|| 
NTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--------DGEGR-HLHLPQLIDMAAQVAEGMA

YLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYE--SAYYRVQGTLVLPIRWMACETF-YGKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEV
||.|....||||| || |||.. ..|. |||  | | .     |  .    .||.|.| | . ||.|..||| | ||. |.|. |   . ||  |. .||
YLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV-PYPGMTNHEV

IQDAIRGPNRKLLPKPEACPREVYD-VMLRCWVHDPAMRADFGEIYSRL
.|   ||     .|.|. || |.|. .||.||  ||  |  |  ... |
LQQVERGYR---MPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK262.AA InsR 620-838 39 8.2e-63 209.77 In-house 58-278 (278) Show / Hide 
Range on Protein: 620-838
Range on HMM: 58-278/278
Sequence Identity: 39% (90 aa)

MSRLNHDNVVRLLAVCTVGE-HFIMMEYMENGDLNQFLQKHTLVPDTVTGLGDWE-----ITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKD
| . |. .||||| ||. |.   . || |. |||  .|    . |. .   .. .     ...  ..    .| .|| || .. ||||||| |||.| .|
MKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLR--SRRPEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHD

FIVKISDFGMSRRLYESAYYRVQGTLVLPIRWMACETFY-GKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRGPNRKLLPKPEACPREVY
| ||| |||| | .||. |||  |   ||.|||| |    |.|. .|| | ||| |||. ||.   || . | |.| .    | ....| .|| ||  ..
FTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQ-PYQGLSNEQVLKYI--GMDGNVLRPPENCPEYWQ

DVMLRCWVHDPAMRADFGEIYSRLYM
..| .|| . | ||  |..| . |  
ELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK262.AA CTKA 681-836 46 5.8e-49 162.59 In-house 135-290 (290) Show / Hide 
Range on Protein: 681-836
Range on HMM: 135-290/290
Sequence Identity: 46% (73 aa)

YIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLY-ESAYYRVQGTLVLPIRWMACETF-YGKFSVKSDTWAFGVTLWEVYTLAMCD
|   ||  || || .. ||||||| ||||.|.   .||.||| .| |  || || |.   |.|.|||| |.   ||||  || ||||| |||. . .   
YMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEK-

PYDEMSDEEVIQDAIRGPNRKLLPKPEACPREVYDVMLRCWVHDPAMRADFGEIYSRL
|.  ||| || | |. .   . || |  ||  .|  |  ||   |. |  |  .   |
PWRHMSDQEVCQ-AYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK262.AA S_TKc 554-838 20 3.9e-40 140.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 554-838
Range on HMM: 1-231/231
Sequence Identity: 20% (62 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMSRLNHDNVVRLLAVCTVGEHFIMMEYMEN--GD
   .||.| | ||.| ..| ..                   .||||..|        | . .|.. ... .|.|.|.|. |.  .. .. |||...  ||
YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGD

LNQFLQKHTLVPDTVTGLGDWE--ITPIILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIVKISDFGMSRRLYESAYYRVQGTLVLPIRWMACE
| ....|.   .        .   ...    ..  || ... |. |....||||   | |. .   .||.|||..|.|          |..    .|| |
LFDYIKKRGRHG--------LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPE

TFYGKFSV-KSDTWAFGVTLWEVYT-LAMCDPYDEMSDEEVIQDAIRGPNRKLLPKPEACPREVYDVMLRCWVHDPAMRADFGEIYS-------RLYM
 .  ...  |.| |..|..|.| ..     .      ..... . |.             ..|. | . .|.. ||. |    |.           ..
VL--GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK262.AA Pkinase 554-838 20 3.4e-29 104.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 554-838
Range on HMM: 1-293/293
Sequence Identity: 20% (68 aa)

VIEIRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDK---EVKFMSRLNHDNVVRLLAVCTVGEHFIM-MEYMEN
   .||.| | ||.| ... .  .                 .||.|..|   |    .  .    |.. | ||||.|.|||. ... . |  | |||.|.
YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEG

G----DLNQFLQKHTLVPDTVTGLGDWEITPI-----ILLYIGVQISSGMHYLGSRRFVHRDLATRNCLVGKDFIV----KISDFGMSRRLYESAYYRVQ
|    ||  ...              |. ...      .  .  || .|. |. |....||||   |.|. ..  .    ||.||| .. ..    ..  
GLYVMDLFDYIST-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-M

GTLVLPIRWMACET--FYGKFSVKSDTWAFGVTLWEVYT-LAMCDPY----DEMSDEEVIQDAIRGPNRKLLPKPEACP-----------------REVY
 |..  ...|| |   .. . . |.| |..|..|.|...    ..      . ... ..|.   ..|..   |..   .                 .|  
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK

DVMLRCWVHDPAMRADFGEIYSRLYM
|.. .|.  ||. |  . .|    ..
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK262.AA CTKA 557-652 35 2.9e-14 44.18 In-house 4-96 (290) Show / Hide 
Range on Protein: 557-652
Range on HMM: 4-96/290
Sequence Identity: 35% (35 aa)

IRKLGNGQFGQVILARTRHLSLVDMKLSETLTDRSQSILVAIKKLKTNAETGLLEAFDKEVKFMS--RLNHDNVVRLLAVCTVGE-HFIMMEYMENGDL
  |.| |..|||  |  .     | |       | .  .||.| || .|  .  .||. |.   |   . | ||.||| |||  .  .  ||.|  |||
MFKIGEGHYGQVFRAWLMP-DPDDFK-----AQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDL
Kinase AqueK262.AA Src 554-568 60 0.009703 5.08 In-house 1-15 (255) Show / Hide 
Range on Protein: 554-568
Range on HMM: 1-15/255
Sequence Identity: 60% (9 aa)

VIEIRKLGNGQFGQV
.  .||||.|||| |
IKLCRKLGQGQFGEV
Kinase AqueK262.AA InsR 554-568 46 0.014527 4.32 In-house 1-15 (278) Show / Hide 
Range on Protein: 554-568
Range on HMM: 1-15/278
Sequence Identity: 46% (7 aa)

VIEIRKLGNGQFGQV
.. ||..| | || |
IVLIRECGQGSFGMV