Gene AqueK233 (A.queenslandica)

AqueK233

Species: A.queenslandica
Alias: AqueK233
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
AqueK233.AA Protein None 498 None Fasta, JSON
AqueK233.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of AqueK233.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK233.AA MST 24-275 68 1.3e-210 675.74 In-house 1-254 (254) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-254/254
Sequence Identity: 68% (175 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDADLQDIIKEISIMQQCDSQYVVKYYGSYF--KNTDLWIVMEYCGAGSVSDIMRIIERPLNEKEIS
||..||.|.|.|| ||||.||..|...|||.|||. |||.|||||||||||.|.|.||||||||  ||...||||||||.|||.|||.|. |.||| .|.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

VIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEVGYDCLADIWSMGITAIEMAEGRPPYAEV
.| . .|.||.|||. .|||||||||||||| .|..|||||||.|||||||||||||||||.|||||||||..||| ||||| ||||||||||.|||...
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDI

HPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
|||||.||||.|||||.|  . .| ||.||...||.|.||.|..|. |||| |.
HPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK233.AA STE20 24-275 53 7.89999999999e-168 563.84 In-house 1-288 (288) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-288/288
Sequence Identity: 53% (154 aa)

FDLLEKIGEGAYGAVYKALHKESGQL----LAIKQVPVDAD------LQDIIKEISIMQQCDSQYVVKYYGSYFKN----TDLWIVMEYCGAGSVSDIMR
..||||||.|.||.|||| ||..|..     |||..... .      ..||.||||||.||.....|||||||.|.    ..|||||||||.||..|||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---IIER-----PLNEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTD----TMA-KRNTVIGTPFWMAPEVIQE----
   ....     |.||..|..| . .|.||.||| ...|||||||.||||. || .|||||||..|||.    ||. ||||..|||.||||||||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-VGYDCLADIWSMGITAIEMAEGRPPYAEVHPMRAIFMIP--TKPPPTLKQ--ADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
  |||. .|||| ||||||||||.|||...|||||.||||  ..||||||.   ...| || ||...||.| ||.||.|. ||.| |.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK233.AA YSK 24-275 52 8e-145 439.18 In-house 1-257 (257) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-257/257
Sequence Identity: 52% (135 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDA---DLQDIIKEISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRI-IERPLNEKE
|  .|.|| | .| |||.  .  ..  ||| .  .    .  || .|| .  ||||.|. |||||| | | |||.||||| ||..| |.     .. || 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

ISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE--VGYDCLADIWSMGITAIEMAEGRPP
|..|    ||||.|||  ||||||||| |.||. .|  ||.|||||||.|||. |||| .|||.|||||||..  ..||  |||||.||||.||| | ||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
|...||||. | || ..||.| .  ..|  | .|.  ||.| ||.||||  || |.|.
YCDYHPMRVMFLIPKNNPPKL-EGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK233.AA STE 24-275 38 7.69999999999e-139 467.55 In-house 1-359 (359) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-359/359
Sequence Identity: 38% (139 aa)

FDLLEKIGEGAYGAVYKALHK------ESGQL---------LAIKQVPVDAD-------------------LQDIIKEISIMQQCD--SQYVVKYYGSYF
....||||.||.| ||||...      ..|..          ||||.... .                   .|.|.|||.||..|.  ....|||||.||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KN-------TDLWIVMEYCGAGSVSDIMR---IIERPLN----------EKEISVIVQYALKG-LEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAG
|.       ..|||.|||...||..||..   .. .|||          |..|..|..  ||| |.||| ...||||||..||||     .||.||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTDTMA----------------KRNTVIGTPFWMAPEVIQE------VGYDCLADIWSMGITAIEMAEGRPPYAEVHPMRAIFMIPTK-----------
||||.||                ||||..||| ||||||||        |||. .|||| |.|.||||.|.||... |||||.||||..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTLKQA-----------------DNFSNEFSDFISRCLVKSPEERPSATSLLQ--HRFV
    |||.|..                  ...| || |||..||.| |..||.|. ||.  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK233.AA PAKL 24-275 50 5.8e-131 441.39 In-house 1-256 (256) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-256/256
Sequence Identity: 50% (129 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPV-DA-DLQDIIKEISIMQQCDSQYVVKYYGSYFKN-TDLWIVMEYCGAGSVSDIMRIIERPLNEKEI
| . || |.|.||.||||.||...  ||||  ..  . . .|| |||.|   | ....| |.||     . .|| |.|| .||. |.| ...  ||||.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

SVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMA-KRNTVIGTPFWMAPEVIQEVGYDCLADIWSMGITAIEMAEGRPPYA
|||.| .|||| ||| |  ||||||| ||||| |.  |.|||||  || |.     |  ||||.|||||.|    |.  .|||| ||||||||.|.||  
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

EVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
.. ||||  ||| .||||..    .| .| ||. .|.|| ||.|.|.  || | | 
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase AqueK233.AA PAKA 24-275 43 7.1e-105 354.72 In-house 1-260 (260) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-260/260
Sequence Identity: 43% (113 aa)

FDLLEKIGEGAYGAVYKALHKESGQL--LAIKQVPVDADLQD--IIKEISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRIIER----PL
.. .||||.|| |.||.|  .. .|    ||||  .... .   || ||..| .|  . .|.|. ||  . .||.|||| ..|.  |.    ..    ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

NEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEVGYDCLADIWSMGITAIEMAEGR
.|. |. ...  |.|||..| |  ||||||  ||||. ||  |..||| . |||.   ||||. ||| |||||||.   ||   ||||.|| ||||.|| 
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPYAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
||| .  | ||.. | |.  | .|..|..| || || ..|| . ...|.||..||.| | 
PPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK233.AA KHS 24-275 47 4.8e-103 347.47 In-house 1-258 (258) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-258/258
Sequence Identity: 47% (124 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDA--DLQDIIKEISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRIIERPLNEKEIS
..|| ..| | || |||| ...|..| |.| . ...  |.. | .|| .|..|    .| |.|||...  |||.|||||.||. || ..   ||.|  |.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTG-PLSELQIA

VIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI---QEVGYDCLADIWSMGITAIEMAEGRPPY
 . . .|.||.||| . |.|||||  ||||. .|. |||||||..|.| |.|||   ||||.||||||    .. ||. | |||..||||||.||  || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

AEVHPMRAIFMIPTKP---PPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
 ..|||||.|.. ||    ||.||. . .|. | .|.  .|.|.|  ||.|. |||| ||
FDLHPMRALFLM-TKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase AqueK233.AA S_TKc 24-275 34 2.7e-97 330.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDADLQDIIKEISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGA--GSVSDIMRIIERP-----LN
...|.|||.||.| |||. ||..|.. |||...     ..|..||.|... .  ..||.|...   ..|..|||||.   |.. |...   |.     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

EKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEVGYDC-LADIWSMGITAIEMAEGR
| ..  ...  ...|||.| .. ||||.|  ||||.   | |..|||.| ||       .|..|||..|||||.   ||..  .|.|| |.. .||. |.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPYAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQ-------HRFV
||.     | ..| .              | |. |||..||.| ||.||.|  .||       | ..
PPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK233.AA Ste20-DD1 24-275 46 6.1e-96 325.04 In-house 1-268 (268) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-268/268
Sequence Identity: 46% (125 aa)

FDLLEKIGEGAYGAVYKA-------LHKESGQLLAIKQVPVDA----DLQDIIKEISIMQQC-DSQYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRII
|  .| || | .| |                .. |.| | ..|    .     ||| |.    |  |.||| | | |   | ||||||  ||. ||| . 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

ERPLNEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE----VGYDCLADIWSMGIT
   | | .|  |.    ||| ||| .| .||||||||.|.|  | .|||||||   .  .  | ||||| |.||.||.|       |||  |||||.|||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIEMAEGRPPYAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
||||||  ||  .| | | || || ..|||||   | | || |||. || . |. ||||  || | |.
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase AqueK233.AA SLK 24-275 43 1.3e-95 323.06 In-house 1-259 (259) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-259/259
Sequence Identity: 43% (113 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPV--DADLQDIIKEISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRIIERPLNEKEIS
....  .|.||.| |||| ||| ... | | . .  . .|.| . || |. .|.  ..|| |..|. . .||...|.|. | |  ||  .|.|| |. | 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

VIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----QEVGYDCLADIWSMGITAIEMAEGRP
.. .. . .|..|| .. ||||.||||||. .||. .||||||. ... || || | ||||.||||||.     ..  ||. |||||.||| ||||.. |
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PYAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
|. |. ||| .. |    ||||.|   .|.||.||. .|||| |. |...  |.||..|
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase AqueK233.AA NinaC 24-275 45 4.6e-94 318.82 In-house 1-267 (267) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-267/267
Sequence Identity: 45% (121 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDADLQDII-KEISIMQQ-CDSQYVVKYYGSYFKNT-----DLWIVMEYCGAGSVSDIMRII---ER
.   | || | || |.|.. |..||. |.|    . |..  |  |  |... ||   ||..|| |.|        ||.|||||  ||| |. . .   .|
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

PLNEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----QEVGYDCLADIWSMGITA
 ..|. |. |.  |. ||  ||  . ||||.|  ||||  .|  || ||||  ||. |  .||| .|||.|||||||      .  ||  .|.||.||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IEMAEGRPPYAEVHPMRAIFMIPTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRFV
||.. | || |. |||||.| ||  ||||| . .| ..|| ||||.|| |  | ||. . .|.|.|.
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase AqueK233.AA Pkinase 24-275 30 1.6e-76 265.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-275
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDADLQDIIK------EISIMQQCDSQYVVKYYGSYFKNTDLWIVMEYCGAG----SVSDIMR-IIE
. ...|||.|..| |||. || .|.. |.|..... .  .  .      ||.||. ... ..|..|...  ......|||||. |    . .|...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPL--NEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHA----KLADFGVAGQL-TDTMAKRNTVIGTPFWMAPEVIQ-EVGYDCLADIWSM
...   |.|.  ..   |.||||.| .. ||||.|  |||.. .||     |..|||.| |. .      .|. |||..||||||.   .|.  .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITAIEMAEGRPPYAEV----HPMRAIFMIPTKPPPTLKQADNFS---------------------NEFSDFISRCLVKSPEERPSATSLLQHRFV
|.. .||. ||||. .     . .. ..||  . .| |.     .                      |. |||..|| | |..||.|. .||| ..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK233.AA Pkinase_Tyr 24-274 27 1.4e-33 114.34 Pfam 1-270 (270) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-270/270
Sequence Identity: 27% (75 aa)

FDLLEKIGEGAYGAVYKALHK----ESGQLLAIKQV--PVDAD---LQDIIKEISIMQQC-DSQYVVKYYGSYF-KNTD--LWIVMEYCGAGSVSDIMRI
  ...|.||||.| |||.  |    . ..  |.| .    . .   ..| ..|..|| |  . . .|..||    .     ..|||||.  |.  |  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

I---ERPLNEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQL--TDTM-AKRNTVIGTPFWMAPEVIQEVGYDCLADIWSM
    ..||. |..  . .   ||.|||. |. ||||. | |.|.. ....| .||| |  .  .|.   ||       .|||||.|..  .    |.|| 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GITAIEMAE-GRPP-YAEVHPMRAIFMI-PTKPPPTLKQADNFSNEFSDFISRCLVKSPEERPSATSLLQHRF
|..  |.   |. | |... . . . .|        ... .| . |  | . .|  . ||.||. . . ....
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI-HEQL
Kinase AqueK233.AA TyrKc 24-274 26 6.9e-27 96.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

FDLLEKIGEGAYGAVYKALHKESGQLLAIKQVPVDADLQDIIKEISIMQQC--DSQYVVKYYGSYFKN-------TDLWIVMEYCGAGSVSDIMRIIERP
  |..|.||||.| |||.  |   .  |.| .  || ..|...|..|| .   . . .|. ||   .          |.|||||.  |.  |  |  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LNEKEISVIVQYALKGLEYLHFKRKIHRDIKAGNILLNLDGHAKLADFGVAGQLTDT----MAKRNTVI----GTP-----FWMAPEVIQEVGYDCLADI
|. |.   .   . .| |||| |. ||||. | |.|.. ....| .||| .  ..|      .|   .     |.       |||||.|..  .    |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSMGITAIEMAE-GRPPYAE-----VHPMRAIFMIPTKPPPTLKQADN--------FSNEFSDFISRCLVKSPEERPSATSLLQHRF
|| |..  |.   | .|| .     . . ..|  . .     ..| .|         . |  . ...|    ||.||. . .  ..|
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Mst1_SARAH AqueK233.AA Mst1_SARAH 409-457 44 1.9e-19 65.37 Pfam 1-49 (49) Show / Hide 
Range on Protein: 409-457
Range on HMM: 1-49/49
Sequence Identity: 44% (22 aa)

FKDYLKGLNDDELEEHMTLLDKRMDEELEALRKRYHQKRQPILQAIDAK
. . || .. .||.. .  ||. | .|.| ||.||..|||||| |..||
DFEFLKSWSYEELQQRLASLDPMMEQEIEELRQRYQAKRQPILDAMEAK