Gene AqueK229 (A.queenslandica)

AqueK229

Species: A.queenslandica
Alias: AqueK229
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
AqueK229.AA Protein None 613 None Fasta, JSON
AqueK229.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of AqueK229.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK229.AA FRAY 32-308 64 1.9e-194 609.75 In-house 1-277 (277) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-277/277
Sequence Identity: 64% (180 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYK-SSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGGSLLDIIKHVMTKGN--K
|||..|||.||||||. |. .||.|..|||||.||  .  ||.|| |||  |. |.||||. |.|||||. ||||||.. ..||.|||.|. | .|.  |
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

GGVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRN-PRYTFVGTPCWMAPEVMDQSVGYDSKADIWS
.||.|| || |||  ||.||.||| |||||||.|||||||||||..|.|||||| ||    ||   |.  | ||||||||||||||.|  ||| ||||||
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLAT--GGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWS

FGITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
|||||.|.|||.|||.|.|||||||||| |.||.|.|  .    |  | |.. |.||.|||||||||||| | ||||   |
FGITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLET--DEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase AqueK229.AA STE20 32-308 44 8.4e-138 464.1 In-house 1-288 (288) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-288/288
Sequence Identity: 44% (134 aa)

YELKDVIGSGATAVVQVAVYVPRNEK----VAIKRIDLEQYK---SSMEELQKEINLMSNCNHPNVINYYTSFVVR----HELWLVMKLMSGGSLLDIIK
||| ..||.|.. .| .|  .| .|.    ||||...||. .    ..|..||||. |..|.|||...||.|...     .|||.|| ...||||.||.|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

HVMTKG--NKGG-VLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRN-PRYTFVGTPCWMAPEVMDQ-
|.|..|  .| | ...|. | .|.. |||||.| | |..||||.||.|||..||| |.||||||. .|  .  . . .. .| ||||||.||||||. . 
HCMKCGKNHK-GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHG-R-DTMQFKRNTFVGTPYWMAPEVIQCM

---SVGYDSKADIWSFGITALEMATGTAPYAKFPPMKVLMLTL--ENPPPTLD-TCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
     |||.|.||||.||||.|||.|  ||....||.......   ||||||  . .        ...|. |. .|.|||||||.|||.|..||| | .
EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-K-------PHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK229.AA STE 32-308 31 3.5e-116 392.27 In-house 1-359 (359) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-359/359
Sequence Identity: 31% (118 aa)

YELKDVIGSGATAVVQVAVYV------PRNEK---------VAIKRIDLEQYK----------------SSMEELQKEINLMSNCN--HPNVINYYTSFV
.|. ..||.||. .|  |...      . .|.         .|||...||. .                . |....|||..|..||  |||...|| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

V-------RHELWLVMKLMSGGSLLDIIKHVMTKGNKG-------GVLDEPVITTILYHVLQG-LEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSN
.       ..|||..| .|.|||| |||||.. .|.         ....|..| .|.. .|.| |.| | .. ||||.|..|||.     | |.||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

WLYGEAGGGKKRN------------PRYTFVGTPCWMAPEVMDQ-----SVGYDSKADIWSFGITALEMATGTAPYAKFPPMKVLMLTLEN---------
 |  .  ..   .             |.|||||| ||||||..|     . ||| |.||||.|.|..|||||  |.....||....... |         
QLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

------PPPTLDTC-------------CELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLK--NPLF
      |||.| .                .    | ...|. |.  ..|||||||.|||.|..|||   | .
LCIVNGPPPPLPDHLSQNEMISYGGSGT-T----YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK229.AA YSK 32-308 42 7.6e-101 304.38 In-house 1-257 (257) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-257/257
Sequence Identity: 42% (120 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGGSLLDIIKH--VMTKGNKG
.   ..|| |   .|  .. .  .. |||| ||||.     | .|.||.  | |  |.. .|| |.     || .|    |||.|| .|   |       
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYV-------

GVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVMDQS-VGYDSKADIWSF
| .||. |..||  .|.||.| | .  |||| || |.|. |.| | |.||||.  .       .|||   |||||| ||||||  |  ..||.|||||| 
GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQ---IKRN---TFVGTPYWMAPEVICQEVSYYDFKADIWSL

GITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRK-NYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
||||.|||.|  ||..  ||.|. |   |.||.|            . .|||.|   || || |||..|||| ||||    
GITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKL-----------EGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK229.AA S_TKc 32-308 30 1.3e-83 285.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-231/231
Sequence Identity: 30% (88 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSG--GSLLDIIKHVMTKGNKG
||. ..||.|| ..|  .. .  ...||||.|.        | ...||..... .|||....| .|.  ..|..|| ...|  |.|.|.||.  ..|.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR-

GVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVMDQSVGYDS-KADIWSF
 ...| ..  ..| ....||| | .| ||||||  |||. |   . ..|||..  |             .||.||| .|||||.    ||.  |.|.||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLK-------NPLF
|..  ||..|  |.    ..... . .                      |. .  ...|||||||.|||.| |.|.        | |
GCILYEMLCGYPPFP--QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK229.AA PAKA 32-308 38 1.3e-82 280.75 In-house 1-260 (260) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-260/260
Sequence Identity: 38% (107 aa)

YELKDVIGSGATAVVQVAVYVPRNEK--VAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGGSLLDIIKHVM-TKGNK
|.  . || ||.  | ||  .  |..  ||||......  ...| .  || .| .|.|.|..||. |..| .|||.||  |.||.| |.|...  .. | 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN-

GGVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVMDQSVGYDSKADIWSF
  ..||  |  ..  .|||||. | ...||||.|  |||.| || | ..|||    |       ...  | | |||| ||||||  .   || | |||| 
--YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLT------QEQQKRNTMVGTPYWMAPEVIRRK-QYDEKVDIWSL

GITALEMATGTAPYAKFPPMKVLMLTLEN-PPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
|| |.||. |  || ..|| . . |   |  |. .|          . . |. |.. ..|||..|. .|.||.|||. | .
GIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKD----------PDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK229.AA MST 32-308 39 3.2e-79 251.43 In-house 1-254 (254) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-254/254
Sequence Identity: 39% (110 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFV--VRHELWLVMKLMSGGSLLDIIKHVMTKGNKG
... . .| |.  .|  |..   .. |||| .  .   . ..|. |||. |..|. ...  || |.      ..|.||    .||..||.|         
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQR-----

GVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYG-EAGGGKKRNPRYTFVGTPCWMAPEVMDQSVGYDSKADIWSF
 .| |  | .||| .||||.| | |  ||||.||||||. ..|.  |||||||  |    |    |||   |..|||.||||||  | ..||.|||||| 
-TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMA----KRN---TVIGTPYWMAPEVI-QEIKYDCKADIWSL

GITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
||||.||| |  ||. . || .. .   .||||.    .         .|  |   | |||||.|..|..|..||. | .
GITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQ---------WSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK229.AA Pkinase 32-308 29 9.4e-68 236.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQK---EINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGG----SLLDIIKHVMT
|... .||||. ..|  .. .  ...||.|.|...  ||....      || .| ..||||.. .| .|  . ....|| .. ||    .| |.|.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

KGNKGGVL--DEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAV----QLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVMDQSVG
   ..|..  .| ..  ..| .|.|||| | .| ||||||  |||| ..| .     ..|||..  ..       .    .||.||| .|||||   . .
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQY

YDSKADIWSFGITALEMATGTAPYAKF------PPMKVLMLTLE--NPPPTLDTCCELNGEDYRK--------NYSKAFQKMVEKCLQKDPSKRPSATEL
|..|.|.||.|..  ||..|  |.          .|... ....  .. .   .|.. . .  |         | |..... ...||.|||.|||.|...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LKNPLF
|. | |
LQHPWF
Kinase AqueK229.AA KHS 32-308 37 7.7e-64 213.57 In-house 1-258 (258) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-258/258
Sequence Identity: 37% (104 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGGSLLDIIKHVMTKGNKGGV
|||   .|||    |  |  .  .| .|.| | .|     .. .|.|| .| .| |||.. |. |.. |  ||..|    |||| || .  .|     | 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEP-GDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYH--VT-----GP

LDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEV--MDQSVGYDSKADIWSFG
| |  |. .   .||||.|.|..|..|||.|  |||. ..| |.|||||||  .      .   . |  |.||| ||||||  ...  ||.   |||. |
LSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQI------TATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVG

ITALEMATGTAPYAKFPPMKVLMLTLENP--PPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
|||.|.|    |     ||..|.|       ||.|           .. .|..| . |  .| |.| |||.|. ||. |..
ITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKD---------KHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase AqueK229.AA MSN 32-308 37 4e-61 200.48 In-house 1-265 (265) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-265/265
Sequence Identity: 37% (108 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSN-CNHPNVINYYTSFV------VRHELWLVMKLMSGGSLLDIIKHVMT
.|| .|.| |.   |   ..|   . .||| .|...     ||...|||..    .| |.. ||  |.       .| ||.|| . . ||. |..|  ||
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVK--MT

KGNKGGVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVM----DQSVGYD
||.    | |  |  |   .|.|| . |..  ||||.|  |.|. ..  |.| |||||  |    |   .||   ||.||| ||||||.    .    ||
KGQ---SLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVG---RRN---TFIGTPYWMAPEVIACDENPDATYD

SKADIWSFGITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
...|.|| ||||.||| |  |  .. ||. |.| . ||||.|            | .|| |.. .|||| |. ..||.. ..|| |  
YRSDLWSVGITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLKS----------KKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase AqueK229.AA SLK 32-308 34 6.3e-61 204.23 In-house 1-259 (259) Show / Hide 
Range on Protein: 32-308
Range on HMM: 1-259/259
Sequence Identity: 34% (98 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNCNHPNVINYYTSFVVRHELWLVMKLMSGGSLLDIIKHVMTKGNKGGV
.|.   .| ||   |. |.   ..   | | |.... .  .|.   ||...|.|.|||... | .. . ..||...    || .  |.  .        .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEH------P

LDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVM----DQSVGYDSKADIWS
| |. |  . .|....|.. | |  |||||||||||.  || |.|||||||      |   .... | ||.||| ||||||.     .   || ||||||
LTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVS------AKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWS

FGITALEMATGTAPYAKFPPMKVLMLTLENPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
.||| .||| .  |.    ||.||.      |||| .  .         .|| |. ...|||.||| .|... .|.. . .
LGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSH---------WSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase AqueK229.AA PAKL 59-308 36 2.9e-60 206.54 In-house 28-256 (256) Show / Hide 
Range on Protein: 59-308
Range on HMM: 28-256/256
Sequence Identity: 36% (93 aa)

AIKRIDLEQYKS-SMEELQKEINLMSNCNHPNVINYYTSFVVR-HELWLVMKLMSGGSLLDIIKHVMTKGNKGGVLDEPVITTILYHVLQGLEYFHTNGQ
||| | .    |   ....|||..  .|. ||.. |. |      ..|  |   | ||  |... .      .  |.|  |  ||  .| || | |  . 
AIKVIEIKE--SNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESC------CKTLNEKQISVILQQTLKGLHYLHSKNI

IHRDLKAGNILIGEDGAVQLADFGVSNWLYGEAGGGKKRNPRYTFVGTPCWMAPEVMDQSVGYDSKADIWSFGITALEMATGTAPYAKFPPMKVLMLTLE
|||| || |||. ||. | .||||||  | .| .| ..       .||| |||||.. .   |..|.|||| |||| ||| |  |    |||. ..    
IHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQ-----MIGTPYWMAPEIINKQ-NYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPN

NPPPTLDTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPSATELLKNPLF
 ||||.            | .|. |   . .|..||| ||.|. .||  |  
WPPPTFSNP---------KHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase AqueK229.AA Pkinase_Tyr 32-251 25 1.3e-29 100.92 Pfam 1-225 (270) Show / Hide 
Range on Protein: 32-251
Range on HMM: 1-225/270
Sequence Identity: 25% (60 aa)

YELKDVIGSGATAVVQVAVYV----PRNEKVAIKRIDLEQYKSS---MEELQKEINLMSNC-NHPNVINYYTSFV-VRHE--LWLVMKLMSGGSLLDIIK
 ..  ..|.||  .|  ...       . .||.| .  |.. ..   .|.. .|...|..  .|||....|   .  .    ...|| .| .|.|||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

HVMTKGNKGGVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWL----YG-EAGGGKKRNPRYTFVGTPCWMAPEVMDQ
      . .. |. . .  . . . .|.|| . .. ||||| | |.|..|.. |  .||| .  .    |   ..|| |   .        |||||..  
KHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK--------WMAPECINY

SVGYDSKADIWSFGITALEMAT-GTAP-YAKFPPMKVL
.. . .| |.||||..  |. | |  | |.  ..  |.
GK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVY
Kinase AqueK229.AA TyrKc 32-317 23 1.3e-24 88.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 32-317
Range on HMM: 1-280/280
Sequence Identity: 23% (74 aa)

YELKDVIGSGATAVVQVAVYVPRNEKVAIKRIDLEQYKSSMEELQKEINLMSNC--NHPNVINYYTSFVVR-------HELWLVMKLMSGGSLLDII-KH
 .|....|.||  .|  ...    ..||.| .  .     .|.. .|...|..   .|||... |   .         . |..|| .|..|.|.| . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

VMTKGNKGGVLDEPVITTILYHVLQGLEYFHTNGQIHRDLKAGNILIGEDGAVQLADFGVSNWLYGE-AGGGKKRNPRYTFV----GTP--C---WMAPE
  .       |  .    . . . .| || | .. ||||| | |.|.||.. |  .||| |  .| . . |    .  |  .    |.       |||||
RPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---ESKDYYRKKEHKGGKTMLPIRWMAPE

VMDQSVGYDSKADIWSFGITALEMAT-GTAPYAK-----FPPMKVLMLTLEN---PPPTL----DTCCELNGEDYRKNYSKAFQKMVEKCLQKDPSKRPS
... .. . .| |.||||..  |. | |  ||        ..  |. .  .    |.|                .    ...  .. ..| . ||..||.
CINYGK-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------F-VCCPDEMYQIMKQCWHEDPEDRPT

ATELLKNPLFKKAKGKEFI
 .|.           .|..
FSEI-----------HECF
Kinase AqueK229.AA Pkinase_Tyr 287-303 35 5.411224 0.6 Pfam 251-267 (270) Show / Hide 
Range on Protein: 287-303
Range on HMM: 251-267/270
Sequence Identity: 35% (6 aa)

KCLQKDPSKRPSATELL
.| ..||..||. .|..
QCWHYDPEDRPTFSEIH
FRWNK_Fray AqueK229.AA FRWNK_Fray 517-609 44 7.3e-31 104.31 In-house 1-97 (97) Show / Hide 
Range on Protein: 517-609
Range on HMM: 1-97/97
Sequence Identity: 44% (43 aa)

KKVLKIALRKRTEQNQLKDIKFDYIIGTDTADAIAKDLLAAGLLEGRELVVVAANISKLIENP--SQKVTFQVGNV--PQEQLDDKKLIGYAQLYVV
.. .   || | ..  |.||.|..  | |||. ||. | .|||  || ||.||||  |||.||     ||||   .  |.|. |.|.|||.||. ..
QPPINLVLRMRNQKKELNDIRFEFTPGKDTAEGIAQELVSAGLVDGRDLVIVAANLQKLIDNPQTMKSVTFQLNSGCQPNEVPDEKALIGFAQISIH