Gene AqueK224 (A.queenslandica)

AqueK224

Species: A.queenslandica
Alias: AqueK224
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: ASK

Sequence

Name Sequence Type Origin Length Description Download
AqueK224.AA Protein None 1012 None Fasta, JSON
AqueK224.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of AqueK224.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ASK_nterm_v5 AqueK224.AA ASK_nterm_v5 49-102 47 1.6e-21 77.79 In-house 1-55 (55) Show / Hide 
Range on Protein: 49-102
Range on HMM: 1-55/55
Sequence Identity: 47% (26 aa)

AFEKLDFGETDALDKFYSSNVAVADVTDRACQAKLFYHLGLRESFEMKQN-IVTY
 |..||||||| .| || . |...|... . |. |||||| |.|| |. | |...
EFMRLDFGETDMFDEFYNADVVIVDMSIDHQQPNLFYHLGVRHSFKMRNNIILYC
TPR_ASK_1 AqueK224.AA TPR_ASK_1 215-245 34 5e-12 39.05 In-house 1-38 (38) Show / Hide 
Range on Protein: 215-245
Range on HMM: 1-38/38
Sequence Identity: 34% (13 aa)

ADILLSLLLSYRDIQAYENMVLLAE------KLPSH-E
.||......|||||| |. |. | |      ..| . .
GDIVHNFMHSYRDIQDYDSMIELVEDLKEGEHIPNCCK
TPR_ASK_2 AqueK224.AA TPR_ASK_2 288-330 65 2.8e-30 95.76 In-house 1-46 (46) Show / Hide 
Range on Protein: 288-330
Range on HMM: 1-46/46
Sequence Identity: 65% (30 aa)

PDTLCLCGRIYKDKFVESGHTD---TGSRDKAILWYRKGFDIQPNE
|| .|.|||||||.|.||. ||   ..|||.|| ||||||.||||.
PDMWCMCGRIYKDMFLESQYTDEAARESRDQAIHWYRKGFEIQPNH
TPR_ASK_3 AqueK224.AA TPR_ASK_3 376-409 70 3.7e-18 66.67 In-house 1-34 (34) Show / Hide 
Range on Protein: 376-409
Range on HMM: 1-34/34
Sequence Identity: 70% (24 aa)

YWTVATFFEISVLAEDYQKASHAAECMFKLRPPY
|| ||||||||.||.||.|.  |.|||||| || 
YWDVATFFEISILACDYHKCMQACECMFKLKPPN
Kinase AqueK224.AA STE 608-848 27 7.1e-93 314.86 In-house 1-359 (359) Show / Hide 
Range on Protein: 608-848
Range on HMM: 1-359/359
Sequence Identity: 27% (99 aa)

HEP-VVLGKGSFGIVYSAIDL------VTKKK---------MAIKEIPERTEG-----------------QFQSLEEEIQLHRHLQ--HENIVQYFGAYS
 |   ..|||.|| || |..        |...         ||||... ...                  ..|....||.......  |.|||.|.|.| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DGG-------IFRIFMEQVPGGSLSHLLKFTWGPLIND-----------EGTIRHYTRQILKG-LGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFGTF
..|          |.|| ..||||. ..| ..|.. ..           |  |....|||||| | |||...|.|||||..|.|.      .|..|||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

Q--------------------------------FMAPEVIASGQRG----YGPPADVWSLGCTVIEMVTGKPPFFELGPP---EAAVFKVGTF-------
                                 .||||||  ...|    |.  .|.||||||.|||.|||||.... |.    .. |. . .       
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KEHPEIPD-------------------VLSKELKSFLLSCFEPEPSKRAIVSELLQ--NSFI
   ...| .||                    .|.|.| |.  |.. .|.||. .|.||.   .||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK224.AA ASK 612-752 63 1.6e-77 257.36 In-house 1-141 (254) Show / Hide 
Range on Protein: 612-752
Range on HMM: 1-141/254
Sequence Identity: 63% (90 aa)

VLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQFQSLEEEIQLHRHLQHENIVQYFGAYSDGGIFRIFMEQVPGGSLSHLLKFTWGPLINDEGTIRHYT
|||||..|||| . |. |....|||||||| . . | | |||.||..|.|.||||| |. |..| |.|||||||||||| ||.  |||. ..| |...||
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYT

RQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFGT
.|||.|| |||...|||||||||||||| ||| .|||||||
KQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGT
S_TKc AqueK224.AA S_TKc 607-848 30 4.9e-76 259.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 607-848
Range on HMM: 1-231/231
Sequence Identity: 30% (80 aa)

LHEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQFQSLEEEIQLHRHLQHENIVQYFGAYSDGGIFRIFMEQVPG--GSLSHLLKFTWGPLIN--
 .   ..|||.|| || ...  |....|||.|.       .... |||.... .|.|||...... | . . ..|| ..|  |.| ...|   ..  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

-DEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG----------TFQFMAPEVIASGQRGYGP-PADVWSLGCTVIEMVTGKPP
 .| ..|.|..||...| |.|...|.|||.| .|.|..    .|||.|||          |  .|||||.     |||. ..|.||.||...||..|.||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQLTTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPP

FFELGPPEAAVFKVGTFKEHPEIPDVLSKELKSFLLSCFEPEPSKRAIVSELLQ-------NSFI
|      ....||.             |.|.|.|.  |.. .|.||  . |.||         ..
FP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK224.AA STE11 607-751 41 6.1e-67 228.7 In-house 1-162 (303) Show / Hide 
Range on Protein: 607-751
Range on HMM: 1-162/303
Sequence Identity: 41% (67 aa)

LHEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEG--------QFQS------LEEEIQLHRHLQHENIVQYFGAYS---DGGIFRIFMEQVPGGSL
 ..  ..|||.|| ||..... | . ||.|.|... .         . ||      ..|||.|..||.|.|||.|.|.     . . . ||||..|||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

SHLLKFTWGPLINDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG
|..|.  |||.. || .||.||.|||.|| ||| ..|.||||||.|.|.. ... .|..|||
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFG
Kinase AqueK224.AA STE20 612-848 32 6.3e-58 198.75 In-house 6-288 (288) Show / Hide 
Range on Protein: 612-848
Range on HMM: 6-288/288
Sequence Identity: 32% (93 aa)

VLGKGSFGIVYSAIDLVTKKK----MAIKEIPERTE----GQFQSLEEEIQLHRHLQHENIVQYFGAYSDG----G-IFRIFMEQVPGGSLSHLLK--FT
..|.||.| || |..  |...     ||| .. ...     ...... ||.  . ..|.|||.|.|.|  .      .. | ||   ||||. ..|  ..
KIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELW-IVMEYCGGGSLTDIMKHCMK

WG------PLINDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG-----------TFQ-----------FMAPEVIASGQ---
.|      |.  .|  |   .|..|.|| |||...|.|||||.||.|... .|..|..|||           |.|           .||||||.  .   
CGKNHKGHPM--NEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTE-DGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPD

RGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAAVFKVGTFKEHP---EI--PDVLSKELKSFLLSCFEPEPSKRAIVSELLQNSFI
 ||.  .|.|||| | |||..|.||.|.. .|  | |.. . .. |   .   |.  |.|.. |. .| . .|.||. .|.||. .||
KGYDYKCDIWSLGITAIEMAEGEPPYFDM-HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK224.AA ASK 754-848 66 8.8e-54 177.17 In-house 160-254 (254) Show / Hide 
Range on Protein: 754-848
Range on HMM: 160-254/254
Sequence Identity: 66% (63 aa)

QFMAPEVIASGQRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAAVFKVGTFKEHPEIPDVLSKELKSFLLSCFEPEPSKRAIVSELLQNSFI
|.||||||  ||||||.|||.||.|||..|| ||||||.||| |.||.|||| .|.|||||. ||.| | |.|.||||.| |||  ..|||. |.
QYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase AqueK224.AA Ciliate-E2 612-848 20 6.2e-50 169.59 In-house 6-365 (365) Show / Hide 
Range on Protein: 612-848
Range on HMM: 6-365/365
Sequence Identity: 20% (76 aa)

VLGKGSFGIVYSAIDLVTKK--------------------KMAIKEIPERTEGQFQSLEEEIQLHR----------------HLQHENIVQYFGAYS--D
..|.|.||.|| . .  ..|                    |. |...    . | .... ||.. |                .|.| ||.... ..   |
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

GGIFRIFMEQVPGGSLSHLLKFTW---GPLIN-----DEGTIRHYTRQILK---------------GLGYLHNQK-IVHRDIKGDNVLVNMYSGQIKISD
   . . || . ||.| ...|  .   .  |.     .|  |.....|||.               .| |||... |.||||| .|.|.      |||.|
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIID

FG------------------------------------------------TFQFMAPEVIAS-------GQRGYGPPADVWSLGCTVIEMVTGKPPFFEL
||                                                |  .||||.. .       .| ||.  .|.||||..  ||..|||||   
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

GPPEAAVFKVGTFKEHPE--------------IPDVLSKELKSFLLS----CFEPEPSKRAI-VSELLQNSFI
        | . ..  ..              ... .|.| | ..      ... .|.||    ...|.. ..
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK224.AA STE11 752-848 45 1.7e-48 167.46 In-house 190-303 (303) Show / Hide 
Range on Protein: 752-848
Range on HMM: 190-303/303
Sequence Identity: 45% (52 aa)

TFQ--------FMAPEVIASGQRG-YGPPADVWSLGCTVIEMVTGKPPFFELGP-PEAAVFKVGTF-KEHPEIPDVLS------KELKSFLLSCFEPEPS
|..        .||||||  ..|. || .||.||||||||||.|||||. ...  . || ||.|.. | ||.||. .|       |.. ||. |||..|.
TPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPK

KRAIVSELLQNSFI
||. ...||| .||
KRPTANQLLQHPFI
Kinase AqueK224.AA STE11-Unclassified 612-752 40 4.9e-46 159.27 In-house 6-153 (308) Show / Hide 
Range on Protein: 612-752
Range on HMM: 6-153/308
Sequence Identity: 40% (61 aa)

VLGKGSFGIVYSAIDLVTKKKMAIKEIPE--------RTEGQ-FQSLEEEIQLHRHLQHENIVQYFGAY--SDGGIFRIFMEQVPGGSLSHLLKFTWGPL
..|||||| ||..... | . ||.|.| .          .   .||...|... ..| |.||||| |.    ....  ||||..||||.. .|.   |..
FIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLN-KYGCF

INDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFGT
  || .|..||.|||.|| ||| ..|.||||||.|.|.    | .|..|||.
--DEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDF-DGICKLTDFGC
Kinase AqueK224.AA Pkinase 607-751 34 5.2e-40 142.55 Pfam 1-157 (293) Show / Hide 
Range on Protein: 607-751
Range on HMM: 1-157/293
Sequence Identity: 34% (54 aa)

LHEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQ--FQSLEE--EIQLHRHLQHENIVQYFGAYSDGGIFRIFMEQVPGG----SLSHLLK-FTW
.|   ..|.|||| || ...  | |. |.|.|. |.|     |..    |||....|.|.|||...... |..   . || ..||    .|.....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPLINDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQI----KISDFG
|... .| ....| .|||.|| |.|...|.|||.| .|.|..   |.|    ||.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFG
Kinase AqueK224.AA MEKK2 608-751 45 4.6e-38 132.77 In-house 2-148 (262) Show / Hide 
Range on Protein: 608-751
Range on HMM: 2-148/262
Sequence Identity: 45% (69 aa)

HEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIP-----ERTEGQFQSLEEEIQLHRHLQHENIVQYFGAYSDGG--IFRIFMEQVPGGSLSHLLKFTWGPL
.   .||.| || ||   |  | . .|.| ..       |    |.|| |||| . |||| ||||.|   | .  .  |||| .||||.   ||  .|.|
RRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKA-YGAL

INDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG
   |   | |||||| |. |||.. |||||||| |.| .  || .|..|||
T--ETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDS-SGNVKLGDFG
Kinase AqueK224.AA CAMK 612-750 19 1.7e-35 111.33 In-house 1-240 (425) Show / Hide 
Range on Protein: 612-750
Range on HMM: 1-240/425
Sequence Identity: 19% (48 aa)

VLGKGSFGIVYSAIDLVTK------------KKMAIKEIPER----------------------------TEGQFQSLEEEIQLHRHLQ-------HENI
.||.||||.|. .|.  |.            .| ||| |. .                            ..   .... ||.....||       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYFGAYSDGGI-------------------FRIFM---EQVPGG----S-LSHLLKFTW-------GPLINDEGTI-----RHYTRQILKGLGYLHNQK
.. . .| |.                     . ..|   | ..||      .... . .        . .. ..| .     |.| |||. .. |.|...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKGDNVLVNMYS----------------GQIKISDF
|||||.| .|.|..  .                ..|||.||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase AqueK224.AA STE11-Unclassified 756-848 42 2.5e-35 122.66 In-house 202-308 (308) Show / Hide 
Range on Protein: 756-848
Range on HMM: 202-308/308
Sequence Identity: 42% (45 aa)

MAPEVIA-SGQRGYGPPADVWSLGCTVIEMVTGKPPFFELGP--PEAAVFKVGTFKEHPEIPDVLS-----------KELKSFLLSCFEPEPSKRAIVSE
||||||  | | |..  .|.|||||||||| |||.|.  . .  ...|..|..  .. |.||  ||            |.| ||  ||.  |.||. ...
MAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQ

LLQNSFI
||| .||
LLQHPFI
Kinase AqueK224.AA MEKK15 608-751 42 2.4e-33 117.1 In-house 2-146 (264) Show / Hide 
Range on Protein: 608-751
Range on HMM: 2-146/264
Sequence Identity: 42% (63 aa)

HEPVVLGKGSFGIVY----SAIDLVTKKKMAIKEIP-ERTEGQFQSLEEEIQLHRHLQHENIVQYFGAYSDGGIFRIFMEQVPGGSLSHLLKFTWGPLIN
    .|||| .| ||    .   |.  |.... ||  |... |.. | ||..| . |.| ||| | |   .  .  |||. |||||.| ..   .|||  
KKGNILGKGAYGTVYCGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIIN-RFGPL--

DEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG
||    .||.|||.|  |||.  .||||||| ||.. |  | ||. |||
DEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVML-MPTGIIKLIDFG
Kinase AqueK224.AA Pkinase 752-848 28 2.3e-22 80.19 Pfam 174-293 (293) Show / Hide 
Range on Protein: 752-848
Range on HMM: 174-293/293
Sequence Identity: 28% (34 aa)

TFQFMAPEVIASGQRGYGPPADVWSLGCTVIEMVTGKPPFFEL-----GPPEAAVFKVGTFKEHPEIPDVLS-------------------KELKSFLLS
|  .||||||  |...|||..|.||.||...||..|.||| .        . . .....  . | ..|   |                   .|.|.|. .
TPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CFEPEPSKRAIVSELLQNSFI
|... |.||    ..||  ..
CLCKDPKKRPTAEQILQHPWF
Kinase AqueK224.AA MEKK15 755-848 38 2.6e-22 77.67 In-house 173-264 (264) Show / Hide 
Range on Protein: 755-848
Range on HMM: 173-264/264
Sequence Identity: 38% (37 aa)

FMAPEVIASGQRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAAVFKVGTF-KEHPEIPDVLSKELKSFLLSCFEPEPSKRAIVSELLQNSFI
.||||||     |||  .|.||.|||| || |.|||. .. .. ||.| .|.     |..|.  | . . |   |   .   |.  |.||. .||
WMAPEVIM--ETGYGRKSDIWSIGCTVFEMATRKPPWADM-DRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase AqueK224.AA MEKK2 755-848 44 7.4e-22 76.02 In-house 172-262 (262) Show / Hide 
Range on Protein: 755-848
Range on HMM: 172-262/262
Sequence Identity: 44% (42 aa)

FMAPEVIASGQRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAAVFKVGTFKEHPEIPDVLSKELKSFLLSCFEPEPSKRAIVSELLQNSFI
.|.|||| .|  |||  |||||.||||.||.| |||. |     ||.||. | .  |..|. .|.. . ||  ||      |    |||.  |.
WMSPEVI-NGE-GYGRKADVWSIGCTVVEMLTEKPPWAEYE-AMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase AqueK224.AA Pkinase_Tyr 607-751 27 2e-21 73.21 Pfam 1-156 (270) Show / Hide 
Range on Protein: 607-751
Range on HMM: 1-156/270
Sequence Identity: 27% (44 aa)

LHEPVVLGKGSFGIVYSAIDL----VTKKKMAIKEIPERTEGQ---FQSLEEEIQLHRHL-QHENIVQYFGAYS-DGGI--FRIFMEQVPGGSLSHLLKF
..   .||.|.|| || ..       || . |.| ..| .  .    ... .|... ..| .|.|||.. |. . .|.     | || .|.|.| . |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T--WGPLINDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG
   ... .. .  . .. .|| ||. ||......|||.   |.||.  ....||.|||
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFG
Kinase AqueK224.AA CAMK 751-848 20 1.6e-19 58.88 In-house 281-425 (425) Show / Hide 
Range on Protein: 751-848
Range on HMM: 281-425/425
Sequence Identity: 20% (30 aa)

GTFQFMA-PEVIAS-G-----------QRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAA--------------VFKVGTFK-EHPEIPD-------
||  .|| |||. . |           ...|||..|.||.|.    |..|.||| .    |                  . | .  ..|....       
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGP

------------VLSKELKSFLLSCFEPEPSKRAIVSELLQNSFI
             .|.| |... .. ...|.||. ... |.  ..
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK224.AA STE-Unique 756-848 27 7.6e-19 63.11 In-house 515-616 (616) Show / Hide 
Range on Protein: 756-848
Range on HMM: 515-616/616
Sequence Identity: 27% (28 aa)

MAPEVIASG---QRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEA-AVFKVGTFKEHP-----EIPDVLSKELKSFLLSCFEPEPSKRAIVSELLQNS
|.||||        .|.  .|.|||||....| .| ||. .... .| .       .. |     .||. ...|.  |. .|.|..|..|. ...||.  
MCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHF

FI
. 
WL
Kinase AqueK224.AA STE-Unique 679-752 36 1.7e-18 61.86 In-house 371-456 (616) Show / Hide 
Range on Protein: 679-752
Range on HMM: 371-456/616
Sequence Identity: 36% (32 aa)

IFMEQVPGGSLSHLLKFTWGP-------LINDEGTIRHYTRQILKGLGYLHNQK--IVHRDIKGDNVLVNMYS----GQIKISDFGT
||||  ..|.|. ..| . .|       |.  |  .  ||.|||.||.||| |.  |.|||.| .|.. .         .||.|||.
IFMEYCEHGTLQQIIKRCGCPGNPNNLQLFP-ETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGH
Kinase AqueK224.AA TyrKc 607-847 23 7.7e-16 33.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 607-847
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

LHEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQFQSLEEEIQLHRHL--QHENIVQYFGAYSDG-------GIFRIFMEQVPGGSLSHLLKFTW
..   .|| | ||.|| ..      . |.| . | .    . . .|... ..|  .|.|||. .|. ...       .   | || .|.|.| . |. . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

GPLINDEGTIRHYTRQILKGLGYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG----------------TFQF--------------MAPEVIASGQRG
.       .  ..  || .|  ||| ....|||.   |.||.    ..||||||                .                 ||||.|   . |
PK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYG

-YGPPADVWSLGCTVIEMVT-GKPPFFE-----LGPPEA-AVFKVGTFKEHPEI--PDV----LSKELKSFLLSCFEPEPSKRAIVSELLQNSF
 . .  |||| | .  |. | |..|  .     . . |. .  | |   . |.   | .     ..|. .  ..| . .|..|   ||.    |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase AqueK224.AA STE-Unique 608-675 29 1.2e-13 44.28 In-house 1-74 (616) Show / Hide 
Range on Protein: 608-675
Range on HMM: 1-74/616
Sequence Identity: 29% (22 aa)

HEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQF------QSLEEEIQLHRHLQHENIVQYFGAYSDGG
 . . .|.|||| |. ... .... .||| |....   |      . . .||...  | |.||| | |.. .||
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG
Kinase AqueK224.AA Pkinase_Tyr 756-842 24 3e-06 21.69 Pfam 181-270 (270) Show / Hide 
Range on Protein: 756-842
Range on HMM: 181-270/270
Sequence Identity: 24% (23 aa)

MAPEVIASGQRGYGPPADVWSLGCTVIEMVT-GKPP-FFELGPPEAAVFKVGTFKEHPEIPDVLSKELKSFLLSCFEPEPSKR----AIVSEL
||||.|. |   .    |||| | .  |..| |. | . .. ..|  . ...   .  ..|.  ..|. . ...| ...|..|    .|...|
MAPECINYGK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL