Gene AqueK219 (A.queenslandica)
AqueK219
Species: A.queenslandica
Alias: AqueK219
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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AqueK219.AA | Protein | None | 1765 | None | Fasta, JSON |
AqueK219.kin_dom | Protein Kinase Domain | None | 260 | None | Fasta, JSON |
Protein domains of AqueK219.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK219.AA | WNK | 157-192 | 69 | 3.3e-24 | 75.0 | In-house | 1-36 (261) | Show / Hide |
Range on Protein: 157-192 Range on HMM: 1-36/261 Sequence Identity: 69% (25 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLDSQ |...|.|||||||||.||||||.|.|||||| |.. MKFDEEVGRGSFKTVYRGLDTETWVEVAWCELQDQK |
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Kinase | AqueK219.AA | Dicty4 | 157-174 | 61 | 0.000175 | 11.06 | In-house | 1-18 (277) | Show / Hide |
Range on Protein: 157-174 Range on HMM: 1-18/277 Sequence Identity: 61% (11 aa) VKYEQEIGRGSFKTVYKG . ||.||.||| .|||| INIEQRIGKGSFGEVYKG |
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Kinase | AqueK219.AA | STE11 | 157-184 | 39 | 0.000192 | 12.31 | In-house | 1-28 (303) | Show / Hide |
Range on Protein: 157-184 Range on HMM: 1-28/303 Sequence Identity: 39% (11 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVA . . ||.|.| ||||.... ||. .| WQKGEIIGKGAFGTVYKCMNVDTGELMA |
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Kinase | AqueK219.AA | STE | 157-184 | 25 | 0.000271 | 11.21 | In-house | 1-43 (359) | Show / Hide |
Range on Protein: 157-184 Range on HMM: 1-43/359 Sequence Identity: 25% (11 aa) VKYEQEIGRGSFKTVYKGLDTE---------------TGVAVA . ..||.|.| ||||... . ||. .| WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMA |
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Kinase | AqueK219.AA | CAMK | 162-183 | 25 | 0.000308 | 8.77 | In-house | 1-36 (425) | Show / Hide |
Range on Protein: 162-183 Range on HMM: 1-36/425 Sequence Identity: 25% (9 aa) EIGRGSFKTVYKGLDTETG--------------VAV ..||||| .|... ...|. ||. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAI |
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Kinase | AqueK219.AA | ULK | 157-184 | 34 | 0.004093 | 6.82 | In-house | 1-32 (329) | Show / Hide |
Range on Protein: 157-184 Range on HMM: 1-32/329 Sequence Identity: 34% (11 aa) VKYEQEIGRGSFKTVYKGLDTET----GVAVA ...| ||| .|||| . .| ...|| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVA |
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Kinase | AqueK219.AA | Pkinase | 157-183 | 44 | 0.008508 | 10.97 | Pfam | 1-29 (293) | Show / Hide |
Range on Protein: 157-183 Range on HMM: 1-29/293 Sequence Identity: 44% (13 aa) VKYEQEIGRGSFKTVYKGLDTETG--VAV . .. ||.||| .|||. . || ||| YHIGRKIGSGSFGCVYKCHHKGTGKIVAV |
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Kinase | AqueK219.AA | Ciliate-E2 | 157-180 | 33 | 0.017026 | 4.36 | In-house | 1-24 (365) | Show / Hide |
Range on Protein: 157-180 Range on HMM: 1-24/365 Sequence Identity: 33% (8 aa) VKYEQEIGRGSFKTVYKGLDTETG | . ||.|.| .|||. . ... YKFIKKIGQGNFGSVYKCKVWKVQ |
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Kinase | AqueK219.AA | TKL | 163-174 | 66 | 0.169641 | 1.17 | In-house | 1-12 (364) | Show / Hide |
Range on Protein: 163-174 Range on HMM: 1-12/364 Sequence Identity: 66% (8 aa) IGRGSFKTVYKG ||.|.| .|||| IGSGGFGEVYKG |
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Kinase | AqueK219.AA | NRBP | 161-188 | 39 | 0.240909 | 0.11 | In-house | 1-27 (261) | Show / Hide |
Range on Protein: 161-188 Range on HMM: 1-27/261 Sequence Identity: 39% (11 aa) QEIGRGSFKTVYKGLDTETGVAVAWCEL | | ...| .|||.|| | | |. QRDVPG-IDCAYLAMDTEEGVEVVWNEV |
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Kinase | AqueK219.AA | Pkinase_Tyr | 157-174 | 38 | 0.335541 | 4.69 | Pfam | 1-18 (270) | Show / Hide |
Range on Protein: 157-174 Range on HMM: 1-18/270 Sequence Identity: 38% (7 aa) VKYEQEIGRGSFKTVYKG .. ...|.|.| .|||| ITFGKKLGEGAFGEVYKG |
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Kinase | AqueK219.AA | WNK | 219-478 | 66 | 3.8e-184 | 599.83 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-261/261 Sequence Identity: 66% (174 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFKEEVAILKTLNHPYILRLFDSWEFVRQSDKKRVLVLITELMTSGTLKSYMRRFKS |...|.|||||||||.||||||.|.|||||| . | .| |. |||||. .|| | || |.|..|.||.| || ||.||||||||||.|..||| MKFDEEVGRGSFKTVYRGLDTETWVEVAWCELQDQKLSKNERQRFKEEAEMLKKLQHPNIVRFYDYWESV-LCGKK-CIVLVTELMTSGTLKTYLKRFKK IKPRVIRSWGRQILRGLSFLHTRTP-PIIHRDLKCDNVFINGTTGLVKIGDLGLA-TLK-RSDVKTVIGTPEFMAPEMYDEVYDESVDVYAFGMCLLEMC .||.| ||| ||||.||.|||||.| |||||||||||.||.|||| ||||||||| ||| .| | ||||||||||||| | |||||||||||||.||| MKPKVLRSWCRQILKGLHFLHTRQPHPIIHRDLKCDNIFITGTTGSVKIGDLGLAVTLKNSSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMA TLEYPYQECSNPAQIYKKVTSGVMPNSLNKVNDPMLKEIIVACTKLSKSARYTVEMLLNHEFF |.||||.||.|.||||.|||.|. |||..|...| .|||| |.. .|. |.... ||||.|| TSEYPYSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF |
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Kinase | AqueK219.AA | S_TKc | 219-478 | 25 | 1.1e-62 | 215.53 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-231/231 Sequence Identity: 25% (70 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFKEEVAILKTLNHPYILRLFDSWEFVRQSDKKRVLVLITELMTS--GTLKSYMRRF . ..||.|.| .|||. ...|| || .. ... |..||| .||.| .|.|... | ...|.. |.|..|... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR KS------IKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLATLKRSDVKTVIGTPEFMAPEMYDEVYDE-SVDVYAFGM .. . . ..|.. .||...| ..| . ||||||| .|.... .||.| |||.. .|..|||..||||. |. ..|....| GRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGC CLLEMCTLEYPYQECSNPAQIYKKVTSGVMPNSLNKVNDPMLKEIIVACTKLSKSARYTVEMLLN-------HEFF .| ||.. . |.. ......||. .| .|..| | . . |.|. .|. |..| ILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | AqueK219.AA | Pkinase | 219-478 | 26 | 4.4e-54 | 190.8 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-293/293 Sequence Identity: 26% (80 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFKE--EVAILKTLNHPYILRLFDSWEFVRQSDKKRVLVLITELMTSG----TLKSY . .. ||.||| .|||. . || || .. .. ..... . |..|.| ||||.|.||.|..| |. . ...|.. | |..| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY MR--RFKSI--KPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGL---VKIGDLGLA----TLKRSDVKTVIGTPEFMAPEM--YDEVYD .. | ... ....... .|||||| ..| . ||||||| .|..|. . . |||.| ||| . . | .|. |||..|||| .. |. ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG ESVDVYAFGMCLLEMCTLEYPYQEC-----SNPAQIYKKVTSGVMPNSLNKVND-------------------PMLKEIIVACTKLSKSARYTVEMLLNH .||....| | ||.. . |.... .. |..... .. . . . .. . .|..| | .. . |.| | .|.| PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH EFF ..| PWF |
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Kinase | AqueK219.AA | STE | 219-478 | 20 | 5.3e-50 | 172.44 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-359/359 Sequence Identity: 20% (77 aa) VKYEQEIGRGSFKTVYKGLDTE---------------TGVAVAWCELLEHKFNK---------------EEQSRFKEEVAILKTLN--HPYILRLFDSWE . ..||.|.| ||||... . ||. .| .. . |. ||. ....|. |.| .| ||.| . ... . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF FVRQSDKKRV-LVLITELMTSGTLKSYMR-RFKSIKP-------------RVIRSWGRQILRG-LSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLG .| . | .. |.| |.| . .. ... || .|. ||||.| |..|| |||||.|..|... ||. | | KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDFG LATLKRSDVK-------------------TVIGTPEFMAPEMYDE-------VYDESVDVYAFGMCLLEMCTLEYPYQECSNPAQIYKKVTS-------- ... ... |..||| .||||. . ||...|.. .| ...||.| ..|. . ... .. . .. VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE ------GVMPNSLNKVND------------------PMLKEIIVACTKLSKSARYTVEMLLN--HEFF | | ... . | .|. | | . . | |.. ||. |.|. QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | AqueK219.AA | CAMK | 224-478 | 16 | 4e-45 | 142.91 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 224-478 Range on HMM: 1-425/425 Sequence Identity: 16% (72 aa) EIGRGSFKTVYKGLDTETG--------------VAVAW-------------------CELLEHKF-----NKEEQSRFKEEVAILKT-------LNHPYI ..||||| .|... ...|. ||. . . | . . . ... |..|.|. |.|| | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LRLFDSWE----------------FVRQSDKKRVLVL-ITELMTSG----TLKSYMRRFKS---------------IKPRVIRSWGRQILRGLSFLHTRT ..|.. .| . .||. ..|. |.|... | | .| .. .. .. | | . |||. .. ..| . IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN PPIIHRDLKCDNVFINGTT----------------GLVKIGDLGLATLKRS--------------------------DVKTVIGTPEFMA-PEMYD---- |.|||||..|. .. . .|| | |.|. ... ||. ||||.|| ||. --IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH -----------EVYDESVDVYAFGMCLLEMCTLEYPYQECS------------NPAQIYKKVTSGVMPNSLNKVNDPM---------------------- . |....|. . | | | . ..|... . |. ....|...| .. .. CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE LKEIIVACTKLSKSARYTVEMLLNHEFF | | . . . |.|.| |||... CKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | AqueK219.AA | Ciliate-E2 | 219-478 | 19 | 5.8e-43 | 145.31 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-365/365 Sequence Identity: 19% (75 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHK-------------------FNKEEQSRFKEEVAILK----------------TLNHPYILRLFD | . ||.|.| .|||. . ... .| .| ..| . .| | |.. .||||.|..... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE SWEFVRQSD-KKRVLVLITELMTSGTLKSYMR------------RFKSIKPRVIRSWGRQILR---------------GLSFLHTRTPPIIHRDLKCDNV ... . .. . |..|. |.|..|.. |... . |. .|||. .| .|| . . |||||.| .|. CFQ-----EKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENI FINGTTGLVKIGDLGLATLKRSD----------------------------------VKTVIGTPEFMAPEMYD----------EVYDESVDVYAFGMCL .. .|| |.||.. | ..|..|||..||||.. . ||...|....|..| LF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL LEMCTLEYPYQECSNPAQIYKK-VTSGVMPN-------------SLNKVNDP-----------MLKEIIVACTKLSKSARYT-VEMLLNHEFF ||.. ..|. |. |. . |. | .|. . ||. . |.| | .|||..| YEMLFGKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP--------EKRITGWEQILNHPWF |
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Kinase | AqueK219.AA | TKL | 225-466 | 19 | 2.3e-40 | 140.42 | In-house | 1-354 (364) | Show / Hide |
Range on Protein: 225-466 Range on HMM: 1-354/364 Sequence Identity: 19% (70 aa) IGRGSFKTVYKG-LDTET-------GVAVAWCELLEHKFNKEEQ-------------------------SRFKEEVAILKTLNHPYILRLFDSWEFVRQS ||.|.| .|||| . .. | || . .| .... ...||. ... |.|| |... . .. IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -------DKKRVLVLITELMTSGTLKSYMRRFKSIKPRVIRSWGRQILRGLSFLHTRT------PPIIHRDLKCDNVFING-------------TTGLVK . . | ...|.. |.| .|. . .. .| ..| ||...||... ||||||||| .|.... .. .| CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK IGDLGLAT-LKRSD---------------------VKTVIGTPEFMAPEMYD-----------------EVYDESVDVYAFGMCLLEMCTLEYPYQECSN |.|.||.. ...| |..||| .||||. . . |.|..|||.||..| |..| . ||.. . ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY P------------AQIYKKVTSGVMPNSLN-----KVNDPM---LKEIIVACTKLSKSAR . .....| .|. . .... .|... | . ..| MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR |
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Kinase | AqueK219.AA | STE11 | 219-478 | 24 | 5.1e-40 | 139.28 | In-house | 1-303 (303) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-303/303 Sequence Identity: 24% (77 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFN-------KEEQS-----RFKEEVAILKTLNHPYILRLFDSWEFVRQSD-KKRVLVLITELMT . . ||.|.| ||||.... ||. .| . ... | || || ..||....|.|||. | | .. . ..| .. . . | . WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYG----CCLHDNQNDHVNIFMEYCP SGTLKSYMR-RFKS--IKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLATLKRSDV-------------KTVIGTPE-- |.|.| | .. ||| .|||.||..|| |||||.| .|.... . ...|..| | |. .. |.. ||| GGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHG--IIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNS ------FMAPEMYD-EV---YDESVDVYAFGMCLLEMCTLEYPYQECSN--PAQIYKKVTS-GVMPNSLNKVND-----PMLKEIIVACTKLSKSARYTV .||||... | |. ..|. ..| . .||.| |. .... |...| ... . .|. .. . ..... | . .. |.|. MMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTA EMLLNHEFF ||.| |. NQLLQHPFI |
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Kinase | AqueK219.AA | NRBP | 223-479 | 32 | 8.2e-37 | 126.87 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 223-479 Range on HMM: 1-261/261 Sequence Identity: 32% (89 aa) QEIGRGSFKTVYKGLDTETGVAVAWCELL--EHKFNKEEQSRFKEEVAILKTLNHPYILRLFDSWEFVRQSDKKRVLVLITELMTSGTLKSYMRRFK--- | | ...| .|||.|| | | |. | | | . . .. | |.|. | .. | ... | || . ||| | || .| .... | QRDVPG-IDCAYLAMDTEEGVEVVWNEVQFSERKNFKAQEEKIRQVFDNLIQLDHQNIVKFHKYWTDTKEE-KPRV-IFITEYMSSGSMKQFLKKTKKNH -SIKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLATLKRSDVKTV---IGTPEFMAPEMYD--EVYDE--SVDVYAFGM ... . . | ||| ||.||. ||||| | || .|| ||.||| .. ...|.| |.||| |. || | ||.|.||| KNMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIGCVWPDAI-HHHVRTCREEMRNMHFFAPE-YGILEVTDLTTAVDIYSFGM CLLEMCTLEYPYQECSNPAQIYKKVTSGVMPNSLNKVNDPMLKEIIVACTKLSKSARYTVEMLLNHEFFA | ||| || . |.| | || .. . . ..||| ...| | . | . . || |. CALEMAVLEI-QSGCQNGESEY--VTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF |
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Kinase | AqueK219.AA | Ciliate-E2-Unclassified | 220-478 | 20 | 2e-34 | 116.79 | In-house | 2-352 (352) | Show / Hide |
Range on Protein: 220-478 Range on HMM: 2-352/352 Sequence Identity: 20% (72 aa) KYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFK-------EEVA----------------ILKTLNHPYILRLFDSWEFVRQSDKKRV | . ||.|.| .||| . ... . | .. .. .| | ..| .|. ||. ..||.|...| .. |.... KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMF----YCFQDKQN-- LVLITELMTSGTLKSYMRRFKS-----------------IKPRVIR-----SWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTG--LVKIGDLGLA . ...|.. |.|. |.. .|. . . .. . .||| ||..|| |||||.|..|.... . .|| |.|.. IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGIS TLKRSD------------------VKTVIGTPEFM----APEMYDE-VYDES----VDVYAFGMCLLEMCTLEYPYQ-ECSNP---------------AQ .. .|..|||..| |||.... ||.| .|....|..| ||.. .||.. .... . KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL IYKKVTSGVMPNSLNK-----VNDPMLKEIIV----ACTKLSKSARYTVEMLLNHEFF . .. . .. .. .| |..| . | . |.| | .||| .| YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | AqueK219.AA | ULK | 219-478 | 22 | 6.3e-33 | 112.32 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-329/329 Sequence Identity: 22% (75 aa) VKYEQEIGRGSFKTVYKGLDTET----GVAVAWCELLEHKFNKEEQSR--------FKEEVAILKTLN--------HPYILRLFDSWEFVRQSDKKRVLV ...| ||| .|||| . .| ...|| .. |.|.... . .| |. |.|.|. ||.| .|.| . .... . YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYD----WFETSNHNNIY LITELMTSGTLKSYMR----------RFKSIKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTT-----------GLVKIGDLGLATLKRS .|.|. |.|..|. . | . ... .||| |. .|| . |||||.| .|. |. . | .||.| |.| . IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH--NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN D------VKTVI------GTPEFMAPEMYDEV-----YDES-VDVYAFGMCLLEMCTLEYPYQECSNPAQI----YKKVTSG------VMPNSLN----- | .| ||| .|||. . |... .|.. .|. . || . ..|.... . |. .| . . . . |. DNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG --KVNDPMLKEIIVACTKLSKSARYTVEMLLNHEFF .. | .|..| . . . | . | |.||..| NDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | AqueK219.AA | Dicty4 | 301-431 | 34 | 4.2e-27 | 87.56 | In-house | 81-228 (277) | Show / Hide |
Range on Protein: 301-431 Range on HMM: 81-228/277 Sequence Identity: 34% (52 aa) TELMTSGTLKSYMRR-----FKSIKPR--VIRS---WGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLAT-----LKRSD-VKTVIG ||.| .|.| | . .|||. |.. .. . ||. ||...| ||||||| .| . ||..|.||.. .| .|..| TEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNW-RVKVCDFGLSQYMKKHEDHKDNQMTACG TPEFMAPE-MYDEVYDESVDVYAFGMCLLEMCTLEYPYQ-ECSNPAQIY || |||| | . |.|..||| ||. | |. | . ||| . ... |.. TPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFV |
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Kinase | AqueK219.AA | TyrKc | 219-478 | 24 | 2.5e-17 | 57.58 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 219-478 Range on HMM: 1-280/280 Sequence Identity: 24% (74 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFKEEVAILKTL--NHPYILRLFDSWEFVRQSDKK----RVLVLITELMTSGTLKSY .. ....|.| | .|||| . . || | |.. . | .| |.. | .|| |.||. ..|. . | ...|.| | ||.| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYG---VCTQQGRNFMYIEPLMIVMEYMPHGDLKDY MRRFKS-IKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLATLKRSD--------VKTV---IGTPE-----FMAPEMY- |. . .... |. || .| ..|| . ..||||| . |. .. |||.| ||. .| .... |. |||| LRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN DEVYDESVDVYAFGMCLLEMCTLEYPYQEC-----SNPAQIYKKVTSG-VMPNSLN-------KVNDPMLKEIIVACTKLSKSARYTVEMLLNHEFF . .. . ||..|| |. |..|. . . ........| .| || | | | . |. | . . | | . . ||.| YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | AqueK219.AA | Pkinase_Tyr | 299-437 | 25 | 3.5e-15 | 52.05 | Pfam | 84-232 (270) | Show / Hide |
Range on Protein: 299-437 Range on HMM: 84-232/270 Sequence Identity: 25% (39 aa) LITELMTSGTLKSYMRR----FKSIKPRVIRSWGRQILRGLSFLHTRTPPIIHRDLKCDNVFINGTTGLVKIGDLGLATLK-------RSDVKTVIGTPE ...|.| | |..| |. ..... . .. .|| .|...|. . .||||| . |. .. . |||.| ||| . |. .. IVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGK-LPIK FMAPE--MYDEVYDESVDVYAFGMCLLEMCTLE-YP-YQECSNPAQIYKKV-TSG |||| .| . . . ||..|| .. |..|. | |... ....|... .| WMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDG |
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Kinase | AqueK219.AA | Dicty4 | 219-279 | 36 | 2.4e-07 | 20.72 | In-house | 1-61 (277) | Show / Hide |
Range on Protein: 219-279 Range on HMM: 1-61/277 Sequence Identity: 36% (22 aa) VKYEQEIGRGSFKTVYKGLDTETGVAVAWCELLEHKFNKEEQSRFKEEVAILKTLNHPYIL . ||.||.||| .|||| . ||| .. .| .. . |. ||.|.. . || |. INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNIC |
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Kinase | AqueK219.AA | Pkinase_Tyr | 219-281 | 31 | 2e-06 | 22.18 | Pfam | 1-69 (270) | Show / Hide |
Range on Protein: 219-281 Range on HMM: 1-69/270 Sequence Identity: 31% (22 aa) VKYEQEIGRGSFKTVYKGLDT----ETGVAVAWCELLEHKFNKEE--QSRFKEEVAILKTL-NHPYILRL .. ...|.|.| .|||| . .|.. || | .. .|. . | .|..|.|.| .|| |.|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL |
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FRWNK_Wnk1 | AqueK219.AA | FRWNK_Wnk1 | 495-567 | 27 | 8.2e-11 | 36.51 | In-house | 19-92 (92) | Show / Hide |
Range on Protein: 495-567 Range on HMM: 19-92/92 Sequence Identity: 27% (20 aa) DSVMVRLVVPRTSK-ENKKNEQESIEFAYNLQTDIPEDIVNDMVKSGILREEDKKNAIRSVRELTDPLTDPAKQ ... .|.. . | | ..| ||| ..|..|.||... .||.||.. |.| | .|.|. .. SAIKLWLWMEDPKKLKGKYKDNEAIEFSFDLEKDVPEEVAQEMVESGFFCEADYKIVAKSIRDRVALIKWKRER |
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OSR1_C | AqueK219.AA | OSR1_C | 497-533 | 26 | 0.001054 | 17.19 | Pfam | 1-38 (38) | Show / Hide |
Range on Protein: 497-533 Range on HMM: 1-38/38 Sequence Identity: 26% (10 aa) VMVRLVVPRTSK-ENKKNEQESIEFAYNLQTDIPEDIV . .| . . | ..| | | |.|......| ||... INLWLRMRDPKKRKGKHKENEAIQFEFDIEKDTPEEVA |
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FRWNK_Wnk2.hmm | AqueK219.AA | FRWNK_Wnk2.hmm | 520-565 | 23 | 0.008186 | 6.93 | In-house | 18-63 (63) | Show / Hide |
Range on Protein: 520-565 Range on HMM: 18-63/63 Sequence Identity: 23% (11 aa) FAYNLQTDIPEDIVNDMVKSGILREEDKKNAIRSVRELTDPLTDPA | . | | ||.| . ||.. . |.... |. .|. . . FKFDLDGDNPEEIAQYMVENDFILESEREKFIEQMRDIIQKAEEMM |
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FRWNK_Wnk2.hmm | AqueK219.AA | FRWNK_Wnk2.hmm | 929-991 | 28 | 6.8e-14 | 44.22 | In-house | 1-63 (63) | Show / Hide |
Range on Protein: 929-991 Range on HMM: 1-63/63 Sequence Identity: 28% (18 aa) DNVISCSLQTSAGQVINFKFSLDYDKPNEIFNNLVKTGHLSQLEGTDFISQFQKVVDTVRSKS |... | |.| ... ||| || |.|.|| . .|. . . | || | ..... . .. DRMVECQLETHNHKMVTFKFDLDGDNPEEIAQYMVENDFILESEREKFIEQMRDIIQKAEEMM |
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OSR1_C | AqueK219.AA | OSR1_C | 944-959 | 37 | 12.495883 | 2.43 | Pfam | 23-38 (38) | Show / Hide |
Range on Protein: 944-959 Range on HMM: 23-38/38 Sequence Identity: 37% (6 aa) INFKFSLDYDKPNEIF | |.| . |.| |. IQFEFDIEKDTPEEVA |