Gene AqueK213 (A.queenslandica)

AqueK213

Species: A.queenslandica
Alias: AqueK213
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
AqueK213.AA Protein None 828 None Fasta, JSON
AqueK213.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of AqueK213.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK213.AA ULK 45-308 32 1.7e-97 330.2 In-house 1-324 (324) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-324/324
Sequence Identity: 32% (107 aa)

YRPGELIGHGAFA-LVFKGQHRQT---RQAVAIKQILLKNIPGKLST--------ARQDEISILKDLK---HPN--IVQLYHYEEMS--NEIYLIMEFCN
|   . .|.|.|.  |.|| . .|    |.||.|.| .|..  | .           . ||.|.| ||   |||  ||.||.. | |  | ||.|||.||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLAEYLQKMKT---------LSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKT---PAASFQSATIKLADFGFARYLNGADMAATLC
|||| .|..| |.         |||. ... .| | |... .||. ||||||||||.|.. .  ||    .  . . ..|.||||||. ..  .|....|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNNNMEQQMC

----------GSPLYMAPEILLGH----RYDNK-ADLWSTGTILYQCLTGRAPFEASNPHALRRR--------------YARETLVPRIPE---GVSPKL
          |.||||||.|| |.     |... .|.|| |.|.|..|.|. ||... .  .  .                 . . ...|.    .||..
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

ADLLLKLLKKNVQERISHSSLITHPFL
 ||. ..|...  .|||   .. ||..
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase AqueK213.AA ULK 45-308 32 2.6e-94 319.65 In-house 1-329 (329) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-329/329
Sequence Identity: 32% (108 aa)

YRPGELIGHGAFALVFKGQHRQTR----QAVAIKQILLK--NIPGKLST------ARQDEISILKDLK--------HPNIVQLYHYEEMS--NEIYLIME
|   . .|.|.|. |.|| . .|     ..||.|.|...  |.  ....        . || |.| ||        |||||.||.. | |  | ||.|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNGGDLAEYLQKMKT----------LSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKT---PAASFQSATIKLADFGFARYLNGA---
.|||||| .|..| |.          |||. ... .| | |... .||..|||||||||| |.. .  ||    .  . . ..|.||||||. ..     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNME

---DMAAT----LCGSPLYMAPEILLGH----RYDNK-ADLWSTGTILYQCLTGRAPFEASNPHALRRRYARETLVPRIPEG------------------
    |...    |||.||||||.|| |.     |... .|.|| |.|.|..|.|. ||.|. .  .  .. .. .  . | .                  
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

VSPKLADLLLKLLKKNVQERISHSSLITHPFL
.||.. ||. ..|...  .|||   |. ||..
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK213.AA S_TKc 45-308 33 1.6e-93 317.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-231/231
Sequence Identity: 33% (93 aa)

YRPGELIGHGAFALVFKGQHRQTRQAVAIKQILLKNIPGKLSTARQDEISILKDLKHPNIVQLYHYEEMSNEIYLIMEFCNG--GDLAEYLQKMKT----
|. ...||.|||. |.|..|. | . ||||.|             . ||.|||  .|||||.|| . .  ...|..||.|.|  ||| .|..|...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFGFARYLNGADMAATLCGSPLYMAPEILLGHRYDN-KADL
  ..|  .|.... | .||. .|...|||||.||.|.||.              .||..|||.|| |       |.||.| |||||.|    |.  |.| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDW

WSTGTILYQCLTGRAPFEASNPHALRRRYARETLVPRIPEGVSPKLADLLLKLLKKNVQERISHSSLIT-------HPFL
|| | ||| .|.|. ||.  ..... ..              || . |.. |.|.|. ..|..   . .       ||..
WSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK213.AA CAMKL 45-308 32 1.4e-82 263.29 In-house 1-297 (297) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-297/297
Sequence Identity: 32% (100 aa)

YRPGELIGHGAFALVFKGQH-RQTRQAVAIKQIL---LKNIPGKLST------ARQD----EISILKDLK---HPNIVQLYHYE-------EMSNEIYLI
|| |. .|.|.|. |  ..| | |.. |||| |    ..|.| ...        . .    ||.|.| |.   ||||..||.         |. ..|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MEFCNGGD--LAEYLQKM----KTLSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFGFARYLN-G----ADMA
|| | ||.  | .|..|     . ..|.  |.. . |  |.. .|...|.|||||| |.||..  |          .||..||||. .   .     .. 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---------NIKIIDFGFSNMYRPCIFGPGQKL

ATLCGSPLYMAPEILLG-HR-YD-NKADLWSTGTILYQCLTGRAPFEASNPH-------ALRRRYARETLVPRIPEGVSPKLADLLLKLLKKNVQERISH
 | |||| ||||||..| .. ||  |.| || | |||  ..|. ||.. . .        |...  .    |.|.  ||  . ||. |.|..|  .|.. 
KTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI

SSLITHPFL
  .  ||..
HQIMNHPWM
Kinase AqueK213.AA CAMK 50-308 21 5.9e-80 257.17 In-house 1-425 (425) Show / Hide 
Range on Protein: 50-308
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

LIGHGAFALVFKGQHRQTR------------QAVAIKQILLKNIPG------------------------KLSTAR--QDEISILKD-------LKHPNI
 .|.|.|. |....|..|             | |||| |  | ...                        . .. .  . ||.|.|        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYHYEEMSN-------------------EIYLIM---EFCNGG----DLAEYLQKM---------------KTLSEESIRHLIKNISNALQVIHKRRI
..||.. | ..                   ..|..|   |.| ||    || .|...                . ..|.  |.... |  |.. .|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPQNLLLSYPPNKTPAASFQS--------ATIKLADFGFARYLNG------------------------ADMAATLCGSPLYMA-PEILLGHR--
.|||.|| |.||..  . ..  . ..        ..||..|||||.....                         ..  | ||.| ||| ||.|.| .  
VHRDLKPENILLDDNNDDSDP-V-EHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------YDNKADLWSTGTILYQCLTGRAPFEAS-------------NPHALRR-----RYA-RETLVPRIP-------EG---------VSPKL
            |. |.| || | ||| .|.|. ||...             |.. | .     .|   .  .. |.        .         ||.  
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

ADLLLKLLKKNVQERISHSSLITHPFL
 ||. |.|... ..|.. .    ||..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK213.AA Pkinase 45-308 30 8.1e-78 269.63 Pfam 1-293 (293) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

YRPGELIGHGAFALVFKGQHRQTRQAVAIKQILLKNIPGKLSTARQD--EISILKDLKHPNIVQLYHYEEMSNEIYLIMEFCNGG----DLAEYLQ--KM
|. |. || |.|. |.|..|. |.. ||.|.| ....  .   ..    ||.|.| |.|||||.||.. | ...||..||.|.||    ||..|..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTL--SEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFGFAR---YLNGADMAATLCGSPLYMAPEILL-GHRYD
...  ||. ... .. |  .|. .|...|||||.||.|.|..   . ..|      ..|..|||.|.   | |.   . |.||.| |||||... |  |.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA------CVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYG

NKADLWSTGTILYQCLTGRAPFEAS----NPHALRRRYARETLVPRIPE----------------------GVSPKLADLLLKLLKKNVQERISHSSLIT
 |.| || | |||. |.|| ||  .    | |  . ...|    |   .                       .|. . |.. ..|.|. ..|..   .  
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPFL
||..
HPWF
Kinase AqueK213.AA Ciliate-E2 45-308 23 4.7e-76 258.99 In-house 1-365 (365) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-365/365
Sequence Identity: 23% (93 aa)

YRPGELIGHGAFALVFKGQHRQTRQ------------------AVAIKQILLKNIPGKLSTARQDEISILK----------------DLKHPNIVQLY-H
|   ..|| |.|. |.|........                   |.||.. .|..  .   .   ||.|..                 |.||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YEE-MSNEIYLIMEFCNGGDLAEYLQKMKTLS-----------EESIRHLIKNISN---------------ALQVIHKRR-IIHRDIKPQNLLLSYPPNK
..|   | |||.||.|.|||| .|....|. .           |. |....| | .               ||. .|..  ||||||||.|.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

TPAASFQSATIKLADFGFARYLNGA--------------------------------DMAATLCGSPLYMAPEILL---------GHRYDNKADLWSTGT
          ||..|||......                                  .|. |.||.| |||||||          ...|| |.|.|| | 
----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

ILYQCLTGRAPFEASNPHALRRRYARETLVPRI---------------PEGVSPKLADLLLK----LLKKNVQERIS-HSSLITHPFL
|||..|.|. ||       ..     .   |                 .. .|..  ||. |    .|.|. ..||.  . .. ||..
ILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK213.AA MARK 45-308 34 5.4e-71 231.34 In-house 1-262 (262) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-262/262
Sequence Identity: 34% (94 aa)

YRPGELIGHGAFALVFKGQHRQTRQAVAIKQILLKNIPG-KLSTARQDEISILKDLKHPNIVQLYHYEE--MSNE-IYLIMEFCNGGDLAEYLQKM--KT
|. .  ||||..| | ...|. |.. |||| .  ...   .     . ||.|.| |.||||..|.|. |   ..  |||||| . ||.| .|...     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSA--TIKLADFGFARYLNGADMAATLCGSPLYMAPEILLGHRYD-NKADL
|.||  |.. . |  |..  |...|.||||||.|.|.            .     ||..||||..  .   .  | ||.| ||||||.|. .||  |.| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILID-----------ENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDI

WSTGTILYQCLTGRAPFEASN--PHALRRRYARETLVPRIPEGVSPKLADLLLKLLKKNVQERISHSSLITHPFL
|| | .||  ..|. ||....     |...  |.  ...||  ||... .|. .||. |  ||.. . .  ||..
WSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRG--KYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AqueK213.AA STE 45-308 22 2.8e-68 233.14 In-house 1-359 (359) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-359/359
Sequence Identity: 22% (86 aa)

YRPGELIGHGAFALVFKGQHRQ---------------TRQAVAIKQILLKNIP---------------GKLSTARQDEISILKDLK--HPNIVQLYHYEE
..  | ||.|||  |.|. ..                | . .||||. |.|                  .     . ||.|.|...  |||||. | ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

MS-------NEIYLIMEFCNGGDLAEYLQ-KMKTLS-------------EESIRHLIKNISNA-LQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSA
         .|....||...|| | . .. |....              |. |.. .. |  . |. .|. .||||||||.| ||               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

TIKLADFGFARYLNG-----------------ADMAATLCGSPLYMAPEILLGHR------YDNKADLWSTGTILYQCLTGRAPFEASNPHALRRRYARE
 .||.|||..  |.                  . .  |..|.| .||||.... .      || |.| || |  .   .||. |.   .|.    . ...
-VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

--------------TLVPRIPE-------------------GVSPKLADLLLKLLKKNVQERISHSSLIT--HPFL
                 |..|.                    .||.. | . | |.|. ..| . | |.   |||.
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK213.AA Ciliate-E2a 45-256 33 7.1e-68 198.89 In-house 1-220 (275) Show / Hide 
Range on Protein: 45-256
Range on HMM: 1-220/275
Sequence Identity: 33% (76 aa)

YRPGELIGHGAFALVFKGQHRQTRQA-VAIKQILLKNIPGKLSTARQDEISILKDLKHPNIVQLYHYEEMSNEIYLIMEFCNGGDLAEYLQKMKTLSEE-
|.   .|| |.|. |.. ||.|| .  ...| |   .. .| . . ..||.|.. |.|||| .|| . |  | .||.||.|.||.| ..... |.. || 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-SIRHLIKNIS-NALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQS---ATIKLADFGFARYLNGADM--AATLCGSPLYMA------PEILLGHRY
  |.......   .|. .|.| |.|||.||.|.|.          |..|   . ||..|||.|.. .. .     . ||.| |.|      .|.|.. .|
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN-------CSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQY

DNKADLWSTGTILYQCLTGRAPFEASN
| | |.|| | |.|  |.|. ||.. .
DTKCDMWSCGVIFYILLCGKPPFKGKT
Kinase AqueK213.AA Ciliate-E2-Unclassified 45-308 25 3.8e-67 229.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

YRPGELIGHGAFALVFKGQHRQTRQAVAIKQILLKNIPGKLSTAR----------QDEIS-------------ILKDLKHPNIVQLYHYEEMSNEIYLIM
|. .. ||.|.|. |.| ||... |. |.|..  ..|  ...  .            ...             ||....||.|| ......  . ||..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFCNGGDLAEYLQKMKT-----------------LSEESIR-----HLIKNISNALQVIHKR-RIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFG
|.|.|||| .|..|.|.                 ..|. ..     .... | ..|. .|.   ||||||||.|.|..   .           ||..|||
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--------NYYIKIIDFG

FARYLN----------------GADMAATLCGSPLYM----APEILLGHRYDNK----ADLWSTGTILYQCLTGRAPFEASNPHA---------------
......                  .|. | ||.| ||    |||.| |. ||..    .| || | |||..|.|. ||.. |                  
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

-LRRRY-ARETLVPRIPE-----GVSPKLADLLL----KLLKKNVQERISHSSLITHPFL
 |..   .... .|  |.     ..||. .|..     |.||||  .||. . .. ||..
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK213.AA NEK 45-308 32 3.4e-61 209.63 In-house 1-286 (286) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-286/286
Sequence Identity: 32% (98 aa)

YRPGELIGHGAFALVFKGQHRQTRQA-----VAIKQILLKNIPGKLSTARQ-DEISILKDLKHPNIVQLYH--YEEMSNEIYLIMEFCN-GGDLAEY---
|.  . || |.|  |.| ..... .      ...|.| ..|   |   . |  |. ||| |||||||  |   .|| .| .. .||.|. ||||..    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

LQKMK----TLSEESIRHLIKNISNALQVIHKR-----RIIHRDIKPQNLLLS-----YPPNKTPAASFQSATIKLADFGFARYLN-GADMAAT-LCGSP
..| |     ..|| | .    .. ||. .|.|     .|.||||||||. |.     |             ..|. ||| .. || ..||| | . | |
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY------------HNVKIGDFGISKVLNHTTDMAYTTQVGTP

LYMAPEILLGHRYDNKADLWSTGTILYQCLTGRA--PFEAS--NPHALRRRYARETLVPRIPEG--VSPKLADLLLKLLKKNVQERISHSSLITHPFL
 ||.||.. .  |.||.| || | .||.  | .   ||||.  | ..|  .  ..   |.||.    |..| .|. ..|.|. ..| | .... .||.
YYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase AqueK213.AA Pkinase_Tyr 45-237 27 2.3e-25 86.53 Pfam 1-199 (270) Show / Hide 
Range on Protein: 45-237
Range on HMM: 1-199/270
Sequence Identity: 27% (58 aa)

YRPGELIGHGAFALVFKGQHR----QTRQAVAIKQILLKNIPGKL--STARQDEISILKDL-KHPNIVQLYHYEE-MSNE--IYLIMEFCNGGDLAEYLQ
 . |. .|.|||  |.||  .    .|.. ||.| .   .   .   . .   |..|.| | .|||||.||      .    ||..||.. .||| .||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KM----KTLSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFGFARYLNGADMA-ATLCGSPL---YMAPEILLG
|     . |. . . .    |.....  . ...||||.   | |..            . ..| .||| ||..   |    .  |..|    |||| .  
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINY

HRYDNKADLWS
 ..  | | ||
GKFTTKSDVWS
Kinase AqueK213.AA TyrKc 45-308 20 6.7e-17 50.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 45-308
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

YRPGELIGHGAFALVFKGQHRQTRQAVAIKQILLKNIPGKLSTARQDEISILKDL--KHPNIVQLYHYEEMS-------NEIYLIMEFCNGGDLAEYLQK
 . |. .|.|||  |.||. .   . ||.| .           .  .|..|.. |  .|||||.|| .   .         ....||.. .||| .||.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MKT-LSEESIRHLIKNISNALQVIHKRRIIHRDIKPQNLLLSYPPNKTPAASFQSATIKLADFGFARYLNGA-------DMAAT----LCG--SPL-YMA
 .  |. .   .    |..  . .|....||||.   | |.. .            |.| .||| .|..          |.  .     .    |.  ||
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEILLGHRYDNKADLWSTGTILYQCLT-GRAPFEA-----SNPHALRRRYARETLVPRIPEG-------VSPKLADLLLKLLKKNVQERISHSSLITHPF
|| .  ...  | | || |  ..  .| |  | .       ..  ....  .    |. |..        .... .. ..  . .  .| . | .  | .
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

L
.
F
Kinase AqueK213.AA Ciliate-E2a 283-308 34 3.7e-05 11.16 In-house 250-275 (275) Show / Hide 
Range on Protein: 283-308
Range on HMM: 250-275/275
Sequence Identity: 34% (9 aa)

DLLLKLLKKNVQERISHSSLITHPFL
||. |.|.|. ..||.   .  ||. 
DLMKKMLEKDPKKRITAQQALNHPWF