Gene AqueK209 (A.queenslandica)

AqueK209

Species: A.queenslandica
Alias: AqueK209
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: Fused

Sequence

Name Sequence Type Origin Length Description Download
AqueK209.AA Protein None 393 None Fasta, JSON
AqueK209.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of AqueK209.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK209.AA Fused 4-254 62 3.1e-172 578.48 In-house 1-251 (251) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-251/251
Sequence Identity: 62% (157 aa)

YHVMELIGEGSFGRVYKGRIKHSKKVVALKFIPKVGRSEIELTNLRREISIMAELSHPNIIELYDCFETPDEVCMVTEFGEGDLFQILEDDTTLPESEIQ
||| |..|.||||.|||.| | . ||||.||||| |||. || |||||. ||... ||.||.. | |||  ||  ||.. |..|.|.||.| ..||  ..
YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAEMELHQYLEYDGKMPEEQVR

VIAVQLVSALFYLHSRRILHRDMKPQNILIGKGRQTKLCDFGFARAMSFQTLVLTSIKGTPLYMCPELVQEKPYDHNSDLWALGCILYELFVGEPPFYTN
 || .|||||.|||| ||||||||||||| .|.   |||||||||.||  |.|||||||||||| |||| |.||||  |.| ||||||||.|| |||..|
RIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLTSIKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCAN

NIVQLVKMITNDDVFFPDTMSNVFNNFLKGLLEKDSSKRLSWPDLLYHPFV
 | .||.||  |||  | |..  . ||| |||.||  .|.|||.||.||||
SIFHLVSMIKHDDVKWPSTITSCCRNFLQGLLTKDPRHRISWPQLLCHPFV
Kinase AqueK209.AA AGC 4-254 22 1.2e-99 257.68 In-house 1-395 (395) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-395/395
Sequence Identity: 22% (91 aa)

YHVMELIGEGSFGRVYKGRIKH------SKKVVALKFIPKVG--------RSEIELTN--------LRREISIMAELS----------HPNIIE-LYDCF
...  .||.||||.||  | |.      ..|. |.| . |            |  .|         ...|  |.....          ||.|.  |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETPDE--VCMVTEF----------GEG-DLFQILE---DDTTLPESEIQVIAVQ-------LVSALFYLHS-RRILHRD-MKPQNILIGKGRQTKLCDFG
...|   ...| |.          | | .||..|    .  ...|.... .| .       .|.|| |||| . | ||| .|| |||. .    ||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FARAMSF--------------------------------------------------QTLVLTSIKG--TPLYMCPELVQEKPYDHNSDLWA--LGCILY
..  .                                                    ..   ... |  || || || .    |..  | |.  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELFVGEPPFYTNNIV----------QLVKMIT------NDDVFFP----------DTMSNVFNNFLKGLLEKDSSKRLS----------WPDLLYHPFV
|. .| |||| .| .          .. . |       |..| ||          . .|.   ...|.||.|| .|||             ..  ||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK209.AA ULK 4-254 29 1.4e-99 337.17 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-329/329
Sequence Identity: 29% (98 aa)

YHVMELIGEGSFGRVYKGRIKHSK-KVVALKFIPKVGRSEIELTN-----------LRREISIMAELS--------HPNIIELYDCFETPDE--VCMVTE
|.. . .|.||||.||||| | .| .|. . .. .. ....   |           |..|| || .|         ||||..|||.|||...  . ...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FGEG-DLFQILEDDTT----------LPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGR------------QTKLCDFGFARAMS-F----Q
. .| ||.|... . .          |.|.|.. .  |..... .||...| |||.||||||| .|             . |..|||||. .. .    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

TLVLTS----IKGTPLYMCPELVQ----EKPYD-HNSDLWALGCILYELFVGEPPFYTNNIVQLV-----KM----------ITNDDVFFP-----DTMS
 .. ..    ..||||||.|...|    .|||. . .|.| ||||.||. .|.||||.. . ...     |           | .    ||     .. |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

NVFNNFLKGLLEKDSSKRLSWPDLLYHPFV
. . ......|..| ..| ||..|. ||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK209.AA S_TKc 4-254 34 9.1e-99 335.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

YHVMELIGEGSFGRVYKGRIKHSKKVVALKFIPKVGRSEIELTNLRREISIMAELSHPNIIELYDCFETPDEVCMVTEFGEG---DLFQILEDDTT----
|.....||.|.||.|||.| |.....||.| |.          ..||||.|. .  ||||. |||.|.. |...||.|. .|   |||.....  .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGRQTKLCDFGFARAMSFQTLVLTSIKGTPLYMCPELVQEKPYDH-NSDLWALGCILYEL
  .|| ... .. |...|| |.||..|.||| ||.|||. .  . |.||||.|| .       |.. ||| || ||..   .|..  .| |..||||||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FVGEPPFYTNNIVQLVKMITNDDVFFPDTMSNVFNNFLKGLLEKDSSKRLSWPDLLY-------HPFV
..|.|||.  .. .. |.|           |  . .|....|.|| .||..  ..|        ||..
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK209.AA Pkinase 4-254 34 1.9e-95 328.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YHVMELIGEGSFGRVYKGRIKHSKKVVALKFIPKVGRSEIELTNLRR--EISIMAELSHPNIIELYDCFETPDEVCMVTEFGEG-----DLFQILE--DD
||. . ||.||||.|||.. | . |.||.| |.|..... .. ..||  ||.||..|.||||..|||.||..|...||.|. ||     ||| ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TTL--PESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGRQT----KLCDFGFARAM-SFQTLVLTSIKGTPLYMCPELVQ-EKPYDHNSDLWAL
...  .| |.. .. |....| |.||..|.|||.||.|||| .  ..    |.||||.|. .       .|.. ||| || ||...  ..|.. .| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCILYELFVGEPPFYTN------NIVQLVKMITNDDVFFPDT---------------------MSNVFNNFLKGLLEKDSSKRLSWPDLLYHPFV
||||||.. |.|||.        .  |....|   .. |.                       .|  .  |.|..|.|| .||......| ||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK209.AA ULK 4-254 29 8e-95 321.32 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-324/324
Sequence Identity: 29% (96 aa)

YHVMELIGEGSFG-RVYKGR--IKH-SKKVVALKFIPKVGRSEIELT--------NLRREISIMAELS---HPN--IIELYDCFETPDE--VCMVTEFGE
| . . .|.||||  |||||  ... ....|| | |.| . .....         .|..||.|| .|    |||  |..|||.|||...  .....|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-DLFQILEDDTT---------LPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGR------------QTKLCDFGFARAMS---FQTLVLTS
| ||.|... . .         |.|.|.. .  |..... .||.. | |||.||||||| .|             . |..|||||.      ..  ....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IK------GTPLYMCPELVQ----EKPYD-HNSDLWALGCILYELFVGEPPFYTNNIVQLV----KM----------ITNDDVFFPD-----TMSNVFNN
..      ||||||.|...|    .|||. . .|.| ||||.||.  |..||... . ...    |.          | |  . ||.       |. . .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FLKGLLEKDSSKRLSWPDLLYHPFV
.....|..| ..| ||.... ||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase AqueK209.AA CAMK 9-254 21 9.2e-79 253.26 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-254
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

LIGEGSFGRVYKGRIKHSK------------KVVALKFIPKVGRS--------------------------EIELTNLRREISIMAELS-------HPNI
 .|.|||| |.... |...            . || |.|.|   .                          .  . |.||||.||  |.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IELYDCFET-------------------PDEVCMVT---EFGEG-DLFQ--------------------ILEDDTTLPESEIQVIAVQLVSALFYLHSRR
| ||. .|.                   .....||.   |. .| .||.                    |. ..  ..|.| . .  |..||. |.||. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDMKPQNILI-GKG----------------RQTKLCDFGFARAMSF-----------------------QTLVLTSIKGTPLYMC-PELVQ------
| ||| || |||.  ..                 . |..|||||. .                         ..  ..   ||| ||. ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EKPYDHNSDLWALGCILYELFVGEPPFYTN-------------NIVQLVKMITNDDV-FFPDTMSNV-----------------------FN
        ...|.  .| |..|.||| . .|.||||               |. .| ..|.. .  | |. .|..                         
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NFLKGLLEKDSSKRLSWPDLLYHPFV
......|..| .||..  . | ||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK209.AA STE 4-254 24 5.4e-74 252.13 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-359/359
Sequence Identity: 24% (91 aa)

YHVMELIGEGSFGRVYKGRIK------HSKKV---------VALKFIPKVGRS---------------EIELTNLRREISIMAELS--HPNIIELYDCFE
.  .| ||.|.|| |||.. .      ....|         .| | ...   .               . |. .. .||.|| ...  ||||.. |.|..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP-------DEVCMVTEFGE-GDLFQILE--------DD------TTLPESEIQVIAVQLVSA-LFYLHSRRILHRDMKPQNILIGKGRQTKLCDFGFAR
         ||.... |. . | | .|..        ..      ...|||.| .|..|.. . | |||| .| ||| ||.|||.      ||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

AMSF----------------QTLVLTSIKGTPLYMCPELVQE------KPYDHNSDLWALGCILYELFVGEPPFYT-NNI---------------VQLVK
 ..                 .    ... ||| .| || .|       |.||  .| | ||| . |.  |.||. . ..                .... 
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-

MITNDDVF-FPD-------------------TMSNVFNNFLKGLLEKDSSKRLSWPDLLY--HPFV
.| |..   .||                    .|  |..|..  |.|| .|| .  .||   |||.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK209.AA NEK 4-254 34 1.8e-72 247.08 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-286/286
Sequence Identity: 34% (98 aa)

YHVMELIGEGSFGRVYKGRIKHSKKV-----VALKFIPKVGR-SEIELTNLR-REISIMAELSHPNIIELYDCFETPD--EVCMVTEFGE--GDLFQI--
| . . ||.||||.||| | |  .|.     ...| |  .|. || |  |.   |. | ..| ||||.. ||.|.  .    | | |. |  |||.|   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-LEDDT----TLPESEIQVIAVQLVSALFYLHSR-----RILHRDMKPQNILIGK-GRQ---TKLCDFGFARAMSFQTLVLTS-IKGTPLYMCPELVQEK
 ..  .     ..|..|  . .|...|| |.|.|     .||||| ||||| . | ...    |. ||| .. ..  |  ...   ||| ||.||..|.|
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

PYDHNSDLWALGCILYELFVG--EPPFYTN--NIVQLVKMITND-DVF-FPDT--MSNVFNNFLKGLLEKDSSKRLSWPDLLYHPFV
||.. || |.|||.|||.     ..||. .  |. .|.. |..  .    |..   |.  .|..  .| || ..| |  ..| .||.
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase AqueK209.AA CAMKL 4-254 30 4.2e-71 226.1 In-house 1-297 (297) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-297/297
Sequence Identity: 30% (92 aa)

YHVMELIGEGSFGRVYKGRI-KHSKKVVALKFIP--KVGRSEIELTN-----------LRREISIMAELS---HPNIIELYDCFETPDE------VCMVT
| . . .|.|||| |  ..  .. .. || |.|   |    .. . |           .||||.||  |.   ||||| ||...|||.       ...|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFGEGD---LFQILEDD----TTLPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIG-KGR-QTKLCDFGFARAMSFQ----TLVLTSIKGTPLYM
|  .|    ||. ..        .||.| . .  |.|||. |.||..| ||| || |||.  .|. . |..||||.  .  .       |.   |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

CPELVQE--KPYD-HNSDLWALGCILYELFVGEPPFYTN--------NIVQLVKMITNDDVFFP--DTMSNVFNNFLKGLLEKDSSKRLSWPDLLYHPFV
.||..|   ||||    | |..| ||| . .|. ||           ||  | ..|  .  ..|    .|    ......|... .|| .  ... ||..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AqueK209.AA Ciliate-E2 4-254 24 4.5e-70 239.12 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YHVMELIGEGSFGRVYKG-RIKHSKKV-----------------VALKFIPKVGRSEIELTNLRREISIM----------------AELSHPNIIELYDC
| . ..||.|.|| |||. ..|  |..                 |. |.. .   .. .. .. .||.||                 .|.|||||..|.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TPDEVCMVTEFGEG-DLFQILEDDTTLP-----------ESEIQVIAVQLVS---------------ALFYLHSRR-ILHRDMKPQNILIGKGRQT
|.  . . . .|.|. .| |||.....  .             | ||. |  |...               || ||||.  |.||| ||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGFAR----------------AMSFQT----------------LVLTSIKGTPLYMCPELVQEKP---------YDHNSDLWALGCILYELFVGEP
|..|||...                 . |                   .  .| ||| ||.|| .. |.         ||. .|.|.||.||||.  |.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFYTNNIVQLVKMITNDDVFFP------------------DTMSNVFNNFLKG----LLEKDSSKRLS-WPDLLYHPFV
||         . | . .. ||                  .  |.   ...|     .|.|| .||.. | ..| ||. 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK209.AA Ciliate-E2-Unclassified 4-254 24 2.1e-65 223.58 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-352/352
Sequence Identity: 24% (86 aa)

YHVMELIGEGSFGRVYKGRIKHSKKVVALKFIPKVGRSE--------------IELTNLR--------REIS-IMAELSHPNIIELYDCFETPDEVCMVT
|.. . ||.|.|| ||| . |  |.. |.| . |.                  .|. |.         ..   |.  . ||.|. ...||.. . ...|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFGEG-DLFQILEDDTT-----------------LPESEIQ-----VIAVQLVSALFYLHSR-RILHRDMKPQNILIGKGR---QTKLCDFGFARAMSFQ
|. || ||.|....  .                 ..| ...      .. |....| |||.   |.||| ||.|||. ..    . |..|||...    .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------TLVLTSIKGTPLYM----CPELVQEKPYD----HNSDLWALGCILYELFVGEPPFYTNNIVQ----------------LVKMITN
                  .... ||| ||     ||. |.. ||    . .| |.||.||||.  |..||| ||  |                | . | .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

DDVFFP--------DTMSNVFNNFLK----GLLEKDSSKRLSWPDLLYHPFV
 ...||        .. |.   .|..     .|.|. .||......| ||. 
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK209.AA Pkinase_Tyr 4-201 28 1.2e-24 84.16 Pfam 1-217 (270) Show / Hide 
Range on Protein: 4-201
Range on HMM: 1-217/270
Sequence Identity: 28% (62 aa)

YHVMELIGEGSFGRVYKGRIK----HSKKVVALKFIPKVGRSEIE--LTNLRREISIMAEL-SHPNIIELYDCFE-TPDE--VCMVTEFGEG-DLFQILE
 . .. .|||.||.||||. |      |  || | . | | .. .  .  . ||..|| .| .||||. || .     .   ...|.|. .. ||   | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----DTTLPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGRQTKLCDFGFARAM---SFQTLVLTSIKGTPL-YMCPELVQEKPYDHNSDLW
.    .  |. ...  ...|  ... ||.|... |||    |.|...... | |||| ||..   .   .. ..    |   | ||  ... . . || |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

ALGCILYELFV-GEPP-FY
. |  ..|.|  || | ..
SFGVLMWEIFTYGEQPTYP
Kinase AqueK209.AA TyrKc 4-253 22 2.6e-16 41.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-253
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YHVMELIGEGSFGRVYKGRIKHSKKVVALKFIPKVGRSEIELTNLRREISIMAEL--SHPNIIELYDCFETP-------DEVCMVTEFGE-GDLFQILED
 .  . .||| ||.||||. |     || | . .       .  ..||..|| .|  .||||. || .  ..       . ...|.|. . ||| . | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

DTT-LPESEIQVIAVQLVSALFYLHSRRILHRDMKPQNILIGKGRQTKLCDFGFARAMSFQ--------TLVLTSIKGTP--L---YMCPELVQEKPYDH
    |. ..   ...|  .   ||||... |||    |.|.|.... | .||| .|.            . . .. ||.   |    | ||  ... . .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

NSDLWALGCILYELF-VGEPPFYT-----NNIVQLVKMITNDDV-FFPDT--------MSNVFNNFLKGLLEKDSSKRLSWPDLLYHPF
 || |. |  ..|.|  |..| .       .  .... . . .    |.         ..    .  |   . | ..| .  .. .. |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF