Gene AqueK205 (A.queenslandica)

AqueK205

Species: A.queenslandica
Alias: AqueK205
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
AqueK205.AA Protein None 1118 None Fasta, JSON
AqueK205.kin_dom Protein Kinase Domain None 162 None Fasta, JSON

Protein domain

Protein domains of AqueK205.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK205.AA SCY1 35-321 28 1.1e-80 274.36 In-house 1-337 (337) Show / Hide 
Range on Protein: 35-321
Range on HMM: 1-337/337
Sequence Identity: 28% (101 aa)

WKVFNGEKKSTKQAVSVFIFYKTAPELEKVPKKERE-ALFELLKKGPTHLAKFRHPKILTVDHPVEESSDCLAFATEPIVASLANVLGYYANLPS-----
||..|| ||.|.|..|||.| |.   .||. |....    |.||| ...|...||| ||.. ||.|||.||...|||.|...|.|||... |..|     
WKIHNGTKKYTGQECSVFVFDKKN--IEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQK

------------PLPPDIKHKPMITGTSTLHEYQVHTLEVHYGLLQLAEGLNFLHNNVKMRHGNLCIDNITISTNGDWKLAG---------FNFASSIES
              |...|            ..    ||| .|..|. ..| |||| ..|.|.|.| ..| .  |||||..|         . | ..|..
TQDVDFGQNTQPQRPYHKK------------DWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQN

ET---PGYSFKET--------------KA--FPLHPTLNYLAPEVVLS-------------NTVNEKCDLYSFGMLIFAIYNSGKPLFDCKDN-LRTYKQ
..   | ....|.              ..   |..| ...||||....              ..  . |..|.|.||...|| .||...|..| . |...
GNPQMPWFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHR

NIEMTSRISESMLGDTPFPLRSL----VRSLLTIEPSVRPDSLQIAKHEFF
 .|  ...|.. ....|  |...    .  ||  .| .|||  |. .|..|
YMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase AqueK205.AA Ciliate-E2 162-321 15 3.2e-14 45.21 In-house 153-365 (365) Show / Hide 
Range on Protein: 162-321
Range on HMM: 153-365/365
Sequence Identity: 15% (37 aa)

QLAE---------------GLNFLHNNVKMRHGNLCIDNITISTNGDWKLAGFNFASSIESE---------------------TPGYSFKETKAFPLHP-
|...               .|..||.. .  | ..  .|| .      |.. | ..  .  .                     ||||..           
QILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD---------QI

-----------TLNYLAPEVVLSNTVN---------EKCDLYSFGMLIFAIYNSGKPLFDCKDNLRTYKQNIEMTSRISESMLGDTPFPLR---------
           |..|.|||.. .   .         .|||..|.|....    .||| |                  . . . ..  ||           
IQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML-FGKPPF------------------QQQIKQCKIDFPCPEWQKDTQCI

---------------SLVRS----LLTIEPSVRPD-SLQIAKHEFF
                | .     .|  .|. |..   || .|..|
QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK205.AA Ciliate-E2-Unclassified 162-321 17 1e-13 43.97 In-house 151-352 (352) Show / Hide 
Range on Protein: 162-321
Range on HMM: 151-352/352
Sequence Identity: 17% (35 aa)

QLAEGLNFLHNNVKMRHGNLCIDNITISTNG---DWKLAGFNFASSIESETPGYSF---------KETKAFPLHPTLNYL----APEVVLSNTVN----E
|. .||..|| . .  | ..  .|| .. ||     |...| ... ...    . .         |. ..     |.||.    ||||  ..  .    .
QILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAY

KCDLYSFGMLIFAIYNSGKPLFDCKDNLR----------------TYKQNIEMTSRISESML----GDTPFPLRSLVR----SLLTIEPSVRPDSLQIAK
||| .|.|......   |.. |....                    |.. ..    ....       . ..    ...    ..|   |. |..  || .
KCDIWSLGVILYEMLF-GYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN

HEFF
| .|
HPWF
Kinase AqueK205.AA AGC 225-321 19 2.8e-13 29.18 In-house 270-395 (395) Show / Hide 
Range on Protein: 225-321
Range on HMM: 270-395/395
Sequence Identity: 19% (26 aa)

TLNYLAPEVVLSNTVNEKCDLYS--FGMLIFAIYNSGKPLFDCKDN----LRTYKQNIEMTSRISESM---LGDTPFP----------------LRSLVR
| .|.|||..     .  || .|  .| |..    .|.| |  ...       ...  ||  .| . .     . .||                ...|..
TPEYMAPEIL----YGKACDWWSFGLGCLMYEML-TGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIK

SLLTIEPSVRPDSLQ----------IAKHEFF
 ||. .|. |. ...          | .|..|
KLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc AqueK205.AA S_TKc 20-321 16 1.3e-11 -6.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-321
Range on HMM: 1-231/231
Sequence Identity: 16% (50 aa)

YELGKQVASAGPGLLWKVFNGEKKSTKQAVSVFIFYKTAPELEKVPKKEREALFELLKKGPTHLAKFRHPKILTVDHPVEESSDCLAFATEPIVASLANV
||..... . . |  .|. . .   |.. | . |                    | ...    | | .|| | .     ..  |.| . .| .  .| ..
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDL

LGYYANLPSPLPPDIKHKPMITGTSTLHEYQVHTLEVHYGLLQLAEGLNFLHNNVKMRHGNLCIDNITISTNGDWKLAGFNFASSIESETPGYSFKETKA
. |  . ... ..                .. .  .. . . |....|...|.. .  |  |  .|| ...    |.. | .|  .              
FDYIKKRGRHGLR----------------FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------

FPLHPTLNYLAPEVVLSNTVNE-KCDLYSFGMLIFAIYNSGKPLFDCKDNLRTYKQNIEMTSRISESMLGDTPFPLRSLVRSLLTIEPSVRPDSLQIAK-
  .  |..|.||||.     .  ||| .|.| ...  .  |.|.|.   .. .  ..|              . ......| .|. .|. ||   .. . 
TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HEFF
      |..|
EWDIKCHPWF
Kinase AqueK205.AA Pkinase 225-321 18 5e-11 40.08 Pfam 174-293 (293) Show / Hide 
Range on Protein: 225-321
Range on HMM: 174-293/293
Sequence Identity: 18% (22 aa)

TLNYLAPEVVL-SNTVNEKCDLYSFGMLIFAIYNSGKPLFDCK------DNLRTYKQNIEMTSRISESMLGDTP-----------------FPLRSLVRS
|..|.||||.. ..    |.| .|.| ...  .. |.|.|. .      | .  .... .   . ... . . .                  ........
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

LLTIEPSVRPDSLQIAKHEFF
.|.  |. ||   || .|..|
CLCKDPKKRPTAEQILQHPWF
Kinase AqueK205.AA PLK1 155-321 29 5.9e-11 31.99 In-house 100-253 (253) Show / Hide 
Range on Protein: 155-321
Range on HMM: 100-253/253
Sequence Identity: 29% (49 aa)

EVHYGLLQLAEGLNFLHNNVKMRHGNLCIDNITISTNGDWKLAGFNFASSIESETPGYSFKETKAFPLHPTLNYLAPEVVLSNTVNEKCDLYSFGMLIFA
|  | . |..||  .|||| |. |  | . |. .  . . |.  |  |  .| .       | |   |  | ||.||||.         |..| | ... 
ECRYYMYQIVEGCQYLHNN-KIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDG------ERKKT-LCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYI

IYNSGKPLFDCKDNLRTYKQNIEMTSRISESMLGDTPFPLRSLVRSLLTIEPSVRPDSLQIAKHEFF
.   |.| |. |    ||..  .   || ...      | ..|.|..|  .|. ||   |. . |||
LL-FGQPPFETKCLKETYSRIKKNEYRIPSHIS----QPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase AqueK205.AA CAMK 225-321 16 1.5e-10 29.5 In-house 282-425 (425) Show / Hide 
Range on Protein: 225-321
Range on HMM: 282-425/425
Sequence Identity: 16% (24 aa)

TLNYLA-PEVVLSNT--------------VNEKCDLYSFGMLIFAIYNSGKPLFDCKDNLRTYKQN-------IEMTSRISESMLG-DTPF---------
|. | | |||.....              ...|||  | | . ..   .|.| |. ... .... .        |.  .| .     . |.         
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIM-LCGYPPFYGDCDNEICE-DEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYG

-----------------PLRSLVRSLLTIEPSVRPDSLQIAKHEFF
                   ..|.|..|. .|. |.   |. .|...
PEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK205.AA TKL 161-319 16 1.3e-08 27.18 In-house 139-364 (364) Show / Hide 
Range on Protein: 161-319
Range on HMM: 139-364/364
Sequence Identity: 16% (37 aa)

LQLAEGLNFLHNNVK-------MRHGNLCIDNITISTNGD--------------WKLAGFNFASSIESET-------------PGYSFKETKAFPLHP-T
|. | |.|.||..         . | .|  .|| .  |.                |.. | .. ... ..             . .. .  |.      |
LDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAE-HQ-NNRKTTMTQCGT

LNYLAPEVVLSN----------------TVNEKCDLYSFGMLIFAIYNSGKPLFDCKDNLRTYKQ---NIEMTSRISESML----------------GDT
....||||   .                . .|||| ||||.... |. .... ... ..   . |    ...  ......                  |.
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL-TRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDC

PFPLRSLVRSLLTIEPSVRPDSLQIAKHE
| ....|       .|. ||  ..| |. 
PPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK205.AA Dicty3 160-252 15 9.8e-08 21.41 In-house 117-287 (351) Show / Hide 
Range on Protein: 160-252
Range on HMM: 117-287/351
Sequence Identity: 15% (27 aa)

LLQLAEGLNFLHNNVKMRHGNLCIDNITISTNG--------------------------DWKLAGFNFASSIESET------------------------
. .|...||..|.| .  |...  ||| .  .                            ||| .| . ..|...                         
ICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNYNNNNNNNNNNNNNNNN

---------------------------PGYSFKETKAFPLHPTLNYLAPEVVLSNTVN--EKCDLYSFGMLI
                            . . |. | ...  | .| |||. | |  .  .| | .|.| ..
NNNNNNNNNNNNNNTNNNVKIINNNIYSNKQYKQ-KCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLGCTV
Kinase AqueK205.AA NZAK 225-255 38 2e-06 17.14 In-house 235-265 (329) Show / Hide 
Range on Protein: 225-255
Range on HMM: 235-265/329
Sequence Identity: 38% (12 aa)

TLNYLAPEVVLSNTVNEKCDLYSFGMLIFAI
| .|.|||.     .||| | .|||.... .
THHYMAPENKNNHRINEKSDVWSFGCTVWQM
Kinase AqueK205.AA MARK 294-321 39 3e-06 16.4 In-house 235-262 (262) Show / Hide 
Range on Protein: 294-321
Range on HMM: 235-262/262
Sequence Identity: 39% (11 aa)

LRSLVRSLLTIEPSVRPDSLQIAKHEFF
.|.|...|||. |. ||.  .| ||...
CRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AqueK205.AA RSK 225-253 30 1.9e-05 16.29 In-house 171-203 (278) Show / Hide 
Range on Protein: 225-253
Range on HMM: 171-203/278
Sequence Identity: 30% (10 aa)

TLNYLAPEVVL----SNTVNEKCDLYSFGMLIF
|..|.|||..      .. .. ||..|.| |..
TIEYMAPEMLKRANQQGGHDKACDWWSLGVLMY
TyrKc AqueK205.AA TyrKc 20-321 16 3e-05 -137.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-321
Range on HMM: 1-280/280
Sequence Identity: 16% (56 aa)

YELGKQVASAGPGLLWKVFNGEKKSTKQAVSVFIFYKTAPELEKVPKKEREALFELLKKGPTHLAKF--RHPKILTVDHPVEESSDCLAFAT--------
 .|||.  .   |   .|. |. |     . | .         |. |..     | . .    . |.  .|| |.           ... .|        
ITLGKKLGE---GAFGEVYKGTWK-----IQVAV---------KMLKEDA---REDFMREARIMCKLGGHHPNIVR----------LYGVCTQQGRNFMY

-EPIVA--------SLANVLGYYANLPSPLPPDIKHKPMITGTSTLHEYQVHTLEVHYGLLQLAEGLNFLHNNVKMRHGNLCI------DNITISTNGDW
 ||.          .| . | .. .                         . . . ..  .| |.| ..|| .        ||       |. .. |.  
IEPLMIVMEYMPHGDLKDYLRKHRPK------------------------LCMKDLLSFCWQIACGMEYLHSK-------NCIHRDLAARNCLVGENHTV

KLAGFNFASSIESE------TPGYSFKE---TKA-FPLHPTLNYLAPEVVLSNTVNEKCDLYSFGMLIFAIYNSGKPLFDC-----KDNLRTYKQNIEMT
| . |  .  |...      .  |. ||   .|. .|.      .|||.   .. ..| | .||| ... |.  |..         ..| . ...  .  
KISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR----WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY

SRISESM-LGD-----TPFPLRSLVRSLLTIEPSVRPDSLQIAKHEFF
 .      .        |  . .. ..    .|. ||   .|  ||.|
RMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AqueK205.AA RSK 295-321 25 0.000423 11.31 In-house 247-278 (278) Show / Hide 
Range on Protein: 295-321
Range on HMM: 247-278/278
Sequence Identity: 25% (8 aa)

RSLVRSLLTIEPSVRPD-----SLQIAKHEFF
..|.| .|. .|. |.        .| .|..|
KDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF