Gene AqueK200 (A.queenslandica)

AqueK200

Species: A.queenslandica
Alias: AqueK200
External Links:
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK200.AA Protein None 563 None Fasta, JSON
AqueK200.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of AqueK200.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK200.AA PLK 34-286 65 1.5e-185 609.09 In-house 1-258 (258) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-258/258
Sequence Identity: 65% (168 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLMELHKRR-KALTEP
||.|.||||||||||||... .|. |||.|.| |.|..||||.|||.|||||||.|.|...|.|| || |..||||.||.|..||||..|||| |.||||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVL--TKKGHSYEVDIWSLGCILYTLLVGKP
||||  .| | .. |||. ..||||||||||||||. ..|.|||||||||| |||||||.||||||||||||  .|.|||||||.||||||.||||.|||
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETKTLKDTYQRIKRNEYHIPHY--VGPEARTLISNLLRPNPANRPTAAEILKDPFF
|||||..|.||.||| |.|..| .  . .||. || ..|..||. |||. .|| .|||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase AqueK200.AA PLK1 34-286 67 3e-164 544.03 In-house 1-253 (253) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-253/253
Sequence Identity: 67% (171 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLMELHKRRKALTEPE
|||||||||||||.|||.. ..|  |.|||.|.|.||.|.||..||||||.|||.|.|.|.|.|| ||.|..||||.||||.|||||||||||||.||||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHSYEVDIWSLGCILYTLLVGKPPFE
 ||  .| |... |||. |.||||||||||||||....|.|||||||..|.||||||||||||||||||||.|||||.||||||.|||.|.||.|.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

TKTLKDTYQRIKRNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILKDPFF
||.||.||.|||.||| ||... . |. || ..| |.| .|||. ..|.| ||
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase AqueK200.AA PLK2 34-286 55 8.10000000001e-151 489.09 In-house 1-257 (257) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-257/257
Sequence Identity: 55% (142 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKR----RSLMELHKRRKAL
| .|. |||||||.|||.   .|. |||.||| ..   |||| ||| .|||.|| | |.|.|.|| .| |  |.|||||.| |    .|.    | |. |
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHSYEVDIWSLGCILYTLLVGK
|||||||  || |  . |||. ..|||||||||.|.||  |.| |||||| |||  .....|.|||||||||||| ..||| | |||.|||| ||.|.| 
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR

PPFETKTLKDTYQRIKRNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILKDPFF
|||||  || ||..|. | ||.|    | || ||. .|.|.|. ||   .|... ||
PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase AqueK200.AA PLK-Unclassified 34-286 55 5e-143 481.45 In-house 1-264 (264) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-264/264
Sequence Identity: 55% (147 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLMELHKRR-------
|..|.|||||||||||. .  ||  .|| ||..|  | |  ...|  .||.|| ||.||..| |  .| |. |||||||.|   .|||..|||       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KALTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVL-TKK-GHSYEVDIWSLGCILYT
| |||.||..   | | |. |||. ..|||||||||.||||. |.|..||||||.|| |||.||| ||||||||||.|  |. |||||||.||.||||||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

LLVGKPPFETKTLKDTYQRIKRNEYHIPH--YVGPEARTLISNLLRPNPANRPTAAEILKDPFF
||.||||||||  | ||..|| |.|  |    .  .|. || . | .||. |||  .|...||.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase AqueK200.AA S_TKc 34-286 33 3.2e-101 343.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKR--RSLMELHKRRKA---
||..| .|||.|.|.|  .  .|| ..| ||.           |.. .||.|...  |...| ....|.| ...|. .|.|     .|... |.|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHSY-EVDIWSLGCILYT
   ..| ..|....|...|..|.|. ..||||||  |..|..  .||..|||||..|       .|.||||.|.|||||   |... ..|.||.||||| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLVGKPPFETKTLKDTYQRIKRNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILK-------DPFF
.|.|.|||.  ... ....|.           |||. .|...|. .|..|||| |.|.       .|.|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK200.AA CAMK 39-286 20 8.3e-97 312.46 In-house 1-425 (425) Show / Hide 
Range on Protein: 39-286
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

FLGKGGFAKCYELICEETG------------TVYAGKIVAKELLVK-------------------------PHQKEKMTQEIEIHRSLS-------HKHV
 ||.|.|.| .. |  .|.            . .| ||. |. | .                         |. .... .||||...|.       |...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGFHGFFDDSNN-------------------VYILL---ELCKRR----SLMELHKRR---------------KALTEPEVRYLFRQTVLAVDYLHDVKV
. .. ...|...                   .|. .   |.|        | .  ...               . .|| |.|..||| . ||.|.|. ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLGNLFLNDD-----------------IEIKLGDFGLATRLEE-----------------------DGERKKTLCGTPNYIA-PEVLTK------
.|||||. |. |.|.                   ||. |||.|.....                       .|.  || |||| |.| |||| .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KGHSYEVDIWSLGCILYTLLVGKPPFETK-------------TLKDTYQRIKRNEYH-IPHYVGP-----------------------EART
        .......|.||.|.|||..|.|.|||. .             ........|.. .|. .|.|. |                       |.. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISNLLRPNPANRPTAAEILKDPFF
||...|...| .|.|....|..|..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK200.AA AGC 34-286 22 1.5e-96 249.49 In-house 1-395 (395) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-395/395
Sequence Identity: 22% (91 aa)

YEKGRFLGKGGFAKCYELICEE--------TGTVYAGKIVAKEL---LVKPHQKEKMTQE------------IEIHRSLS----------HKHVVG-FHG
.|  . .|||.| |.|   ...        || .|| |.. |.    . | .. |.   |             .|   ..          |  .|   | 
FEFLKVIGKGSFGKVY--LVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY

FFDDSNN--VYILLELCK----------R-RSLMELHK--RRKALTEPEVRYLFRQ-------TVLAVDYLHD-VKVIHRD-LKLGNLFLNDDIEIKLGD
 | | ..  .|...|...             ... |..  ... ..|...|. . .       .|||..|||.  ..|||| ||. |. |..|  ||| |
SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTD

FGLATRLEEDG--------------------------------------------------ERKKTLCG--TPNYIAPEVLTKKGHSYEVDIWS--LGCI
|||....  ||                                                  .| .|.||  ||.|.|||.|    .....|.||  |||.
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCL

LYTLLVGKPPFETKTLK----------DTYQRIK------RNEYHIP----------HYVGPEARTLISNLLRPNPANRPT----------AAEILKDPF
.| .|.|.|||  ..            ...|.|.       .. ..|           .. |||. ||. || ..|..|..          | || . |.
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

F
|
F
Kinase AqueK200.AA Aur 34-286 32 6.9e-92 242.6 In-house 1-257 (257) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-257/257
Sequence Identity: 32% (84 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLMELHKRR--KALTE
 | |. |||| | . |  .  .|.  .| |.. || . |   .. . .||.|. .|.| ..  ..|.| |....|..||   . .| .. ..   | ..|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

PEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLND-DIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHSYEVDIWSLGCILYTLLVGKP
..  . ..|. .|.||.|  ..||||.|  |. | . . .||..||| ..   .  .| .|.|||  |..||.   ..| ..||||.|| ..| |..|.|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPN-NNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCP

PFET-KTLKDTYQRIK-RNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILKDPFF
|||  .. . ||.||| .... .| .. .||. |||..|. .| .| | ..|.. |..
PFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase AqueK200.AA Pkinase 34-286 28 1.1e-89 309.0 Pfam 1-293 (293) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMT-QEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRR----SLMELHK--RR
|..|| .|.|.|...|. .   || ..| ||. |.   .  ....   .||.|...|.|...| ....| |....|. .|.|       .|... .  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KAL--TEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEI----KLGDFGLATRL-EEDGERKKTLCGTPNYIAPEVLT-KKGHSYEVDIWSL
...  .| |..  ..|.. ...|.|. ..||||||. |...... .|    |..|||||  . .  ..  .|.||||.|.||||.   ......||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCILYTLLVGKPPFETK------TLKDTYQRIKRNEYHIPHYVG---------------------PEARTLISNLLRPNPANRPTAAEILKDPFF
||||| .| |.|||  .      . .  ..||.. ..| . .                       .|.. .|...|...|. ||||..||..|.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK200.AA CAMKL 34-286 28 1.4e-82 263.33 In-house 1-297 (297) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YEKGRFLGKGGFAKCYELIC-EETGTVYAGKIVAKELLVKPHQKEKM------------TQEIEIHRSLS---HKHVVGFHGFFDDSNN------VYILL
|. |. ||||.|.|    .    ||. .| ||. |. . .  ...|.            ..||.|...|.   |.... ..  ......      .|. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCKRRS--LMELHKRR----KALTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDI--EIKLGDFGLATRLEE----DGERKKTLCGTPNYI
|.|   .  |..  ...    . ..|.| | .||| | ||.|.|. ...|||.|. |. | ..    ||. |||...  ..    .|.  || ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLTK--KGHS-YEVDIWSLGCILYTLLVGKPPFETKTLK-------DTYQRIKRNEYHIPHYVGP-EARTLISNLLRPNPANRPTAAEILKDPFF
|||.. .  | .  ..|||||.| |||....|. ||.  |..         | .|..  |..|... . ..| ||. .| .||  |||. .|...|..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AqueK200.AA SAK 34-286 40 7.5e-82 278.23 In-house 1-254 (254) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-254/254
Sequence Identity: 40% (103 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLME-LHKRRKALTEP
|. .  |||||||  |   | .|.   | |.. | |. |    ... .|.|||  | |  ..    .|.|.| ||. ||.|.   .   ...| .  || 
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHSYEVDIWSLGCILYTLLVGKPPF
| | ...| |  . |||   ..|||| | |. |  |...|. |||||| |.   |.  |.|||||||.||. |.  |  . |.|||||.|||||.|.|||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETKTLKDTYQRIKRNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILKDPFF
.| . | |  ..   || .| ..  ||. ||  .|| ||..| |   .|  || 
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase AqueK200.AA MARK 34-286 35 8.9e-80 260.46 In-house 1-262 (262) Show / Hide 
Range on Protein: 34-286
Range on HMM: 1-262/262
Sequence Identity: 35% (93 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSLSHKHVVGFHGFFD--DSNN-VYILLELCKRRSLMELHKRR--KA
|. .. .|.|..|| .  .   ||. .| ||. |. | .|.....   ||||...|.|.... ..  ..  .... .|. .|.. . .|..  | .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDI--EIKLGDFGLATRLEEDGERKKTLCGTPNYIAPEVLTKKGHS-YEVDIWSLGCILYTL
|.|.| | .||| | || |.|.  ..|||.|. |. . ..    ||. |||.... .. |.. .| |||| | |||.. ||    ..||||||| .||..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPP-GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LVGKPPFE--TKTLKDTYQRIKRNEYHIPHYVGPEARTLISNLLRPNPANRPTAAEILKDPFF
..|. ||.  |...|. |..| | .|.||..| .|.| ||. || .||  |||. ||.|.|..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AqueK200.AA TyrKc 34-284 20 2e-15 26.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-284
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

YEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVKPHQKEKMTQEIEIHRSL--SHKHVVGFHGFFDDS-------NNVYILLELCKRRSLME-LH
 ..|. || | | . |. .          .   | |      .| . .|..| ..|  .|...| ..|   ..         ..|..|...  .| . |.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRRKALTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEED---GERKKTLC-----GTP-----NYIAPEVLTKKGHS
|.|. |. ..  .   |     .|||. ..|||||   |  ....  .| .||||.  ...|   ||.|..       |.         |||.. ..  .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YEVDIWSLGCILY---TLLVGKPPFET-----KTLKDTYQRIKRNEY-HIPHY--------VGPEARTLISNLLRPNPANRPTAAEILKDP
 . |.|| |  ..   |.  |..| .      .. .. ....|. ..  .|..          .|  ....   . .|..||| .|| .. 
TKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK200.AA Pkinase_Tyr 73-248 23 2.2e-13 45.94 Pfam 42-233 (270) Show / Hide 
Range on Protein: 73-248
Range on HMM: 42-233/270
Sequence Identity: 23% (46 aa)

PHQ--KEKMTQEIEIHRSL-SHKHVVGFHGFFD-DSNN--VYILLELCKRRSLME-LHKR---RKALTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGN
..|  .|.. .|..| ..| .|...| ..|    ..    .|| .|...  .| . |.|.   ...|| ..     .|   . .||.. . |||||   |
HEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARN

LFLNDDIEIKLGDFGLATRL-EEDGE-RKKTLCGTP-NYIAPEVLTKKGHSYEVDIWSLGCILYTLLV-GKPP-FETKTLKDTYQRI-KRNE
  ....  .| .|||||  . ..|   ||.. .  |    |||..  .  . . |.|| |  .. ..  |. | ..  .  . |..| ....
CLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
POLO_box AqueK200.AA POLO_box 403-466 33 4.5e-23 87.76 Pfam 1-74 (74) Show / Hide 
Range on Protein: 403-466
Range on HMM: 1-74/74
Sequence Identity: 33% (25 aa)

YTDKYGLGYQLCDNSIGVL-FNDFSKLLLGADGE-SMQHIS--QNMTEQFLTLSQ------YPESMHKKVTLIK
| .|||..|||......|. ||| .|..| .... . ..|.  .| ..| ..||.      |||...||.|..|
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK
POLO_box AqueK200.AA POLO_box 501-547 54 1.2e-18 72.5 Pfam 1-50 (74) Show / Hide 
Range on Protein: 501-547
Range on HMM: 1-50/74
Sequence Identity: 54% (27 aa)

SRTRSAIVFHLSNGTLQINFFQDHTKIIICPLMQ-AVTYID--EQKPSSQ
 ||...|...||||| |.||| ||||||.|| |. ||||||  ... ...
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQT