Gene AqueK188 (A.queenslandica)

AqueK188

Species: A.queenslandica
Alias: AqueK188
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK188.AA Protein None 981 None Fasta, JSON
AqueK188.kin_dom Protein Kinase Domain None 344 None Fasta, JSON

Protein domain

Protein domains of AqueK188.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK188.AA S_TKc 614-968 15 2.2e-12 4.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 614-968
Range on HMM: 1-231/231
Sequence Identity: 15% (57 aa)

LPHTRVIREGGNGLILEVTFEG--ATYAVKKT-ALRWREILIMPKLHHPNVLNLISMMIGYPIDLFPRQRHVFHFYSRMTN---DLGRSVGSYERFCLRS
    |.| .|. |    ..  .    .|.|.     .||| |. | ||||. .|. ..            |.. .   . .   ||        .  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDL--------FDYIKK

LNERYKNEPLLLKKIDNNFKHLFSSILKALDYLHTLPNPVIHRDVKPSNVLIKMSCGCQNPLICVCVTKPQIMLSDFDASLELNSDNSMKPDPPKNSLRD
 . . .. |.    .    ....  |..||.|.| .   .||||.||.|.|.                  .|...||  . .|                 
RGRHGLRFPFPE-HA----RFYMYQICCALEYCHSH--GIIHRDLKPENILLDE----------------HIKICDFGLARQL-----------------

FHLSADRTYHVSPVGTIGFKSPEGFMYMITNDASLLGDMTT-KTDIFSFG-----MLVCLVLLNEEGPKFLNQIGTLLLSAQQSKHIAVNQLDEMKRKIL
           . .||  . .|| .              .. | |. |.|     ||.   .   .  . ...||                         
----------TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-------------------------

QKNGVMYFREREPRVTDKDIFKILPIVRLKQFFSEVNPNLVNFVEMTLAVEPKDRASANALLH-------HLYI
                                     | . .|..  | ..|..| .|  .|.       | ..
------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK188.AA MEK3 732-759 67 4.6e-10 30.4 In-house 110-136 (264) Show / Hide 
Range on Protein: 732-759
Range on HMM: 110-136/264
Sequence Identity: 67% (19 aa)

SILKALDYLHTLPNPVIHRDVKPSNVLI
|| .|| |.|.  . |||||||||||||
SIVSALHYMHEQLK-VIHRDVKPSNVLI
Kinase AqueK188.AA STE-Unique 733-759 55 4.8e-10 31.29 In-house 412-438 (616) Show / Hide 
Range on Protein: 733-759
Range on HMM: 412-438/616
Sequence Identity: 55% (15 aa)

ILKALDYLHTLPNPVIHRDVKPSNVLI
||..|.|||.  ||.||||.||.|...
ILEGLEYLHSQHNPIIHRDLKPHNIFC
Kinase AqueK188.AA STE 732-794 29 7.3e-10 31.13 In-house 159-201 (359) Show / Hide 
Range on Protein: 732-794
Range on HMM: 159-201/359
Sequence Identity: 29% (19 aa)

SILKA-LDYLHTLPNPVIHRDVKPSNVLIKMSCGCQNPLICVCVTKPQIMLSDFDASLELNSDN
.|||. |.||| .   .||||.||.|.|.                   . |.||  .  |....
QILKGLLYYLHSHH--IIHRDIKPANILL-------------------VKLCDFGVCGQLTDSM
Kinase AqueK188.AA STE7-Unclassified 732-759 42 1e-09 30.54 In-house 127-153 (301) Show / Hide 
Range on Protein: 732-759
Range on HMM: 127-153/301
Sequence Identity: 42% (12 aa)

SILKALDYLHTLPNPVIHRDVKPSNVLI
.....|.|||   . .||||.||.|.|.
QVIHGLWYLHEKHH-IIHRDIKPGNILV
Kinase AqueK188.AA Pkinase 727-830 20 1.8e-09 34.54 Pfam 111-181 (293) Show / Hide 
Range on Protein: 727-830
Range on HMM: 111-181/293
Sequence Identity: 20% (21 aa)

KHLFSSILKALDYLHTLPNPVIHRDVKPSNVLIKMSCGCQNPLICVCVTKPQIMLSDFDASLELNSDNSMKPDPPKNSLRDFHLSADRTYHVSPVGTIGF
|. .  ||..|.|.|     .||||.||.|.||.  . .             . ..||  .  ..                       .   ...||...
KFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDA----------CVKICDFGLAKQFD-------------------Y-NNS-MTTFCGTPWY

KSPE
 .||
MAPE
Kinase AqueK188.AA STE7 732-759 53 2.6e-09 30.38 In-house 118-144 (288) Show / Hide 
Range on Protein: 732-759
Range on HMM: 118-144/288
Sequence Identity: 53% (15 aa)

SILKALDYLHTLPNPVIHRDVKPSNVLI
...|.|.|||.  . .|||||||||.|.
AVIKGLHYLHEKHK-IIHRDVKPSNILV
Kinase AqueK188.AA CMGC 705-784 21 3.8e-09 25.24 In-house 145-248 (513) Show / Hide 
Range on Protein: 705-784
Range on HMM: 145-248/513
Sequence Identity: 21% (23 aa)

LRSLNERYKN-EPLLLKKID----------NNFKHLF------SSILKALD--YLHTLPNPVIHRDVKPSNVLIKMSCGC--------QNPLICVCVTKP
... . .|..  |. |.             .| |...        ||..|.  |.|   . .|||| ||.|.||   | .        .. . ..|. . 
IKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSED-W-NPCQKNG

QIMLSDF
.. . ||
RLKICDF
Kinase AqueK188.AA YSK 733-759 59 4.1e-08 20.15 In-house 108-132 (257) Show / Hide 
Range on Protein: 733-759
Range on HMM: 108-132/257
Sequence Identity: 59% (16 aa)

ILKALDYLHTLPNPVIHRDVKPSNVLI
|||.|||||   . .||||.|  |||.
ILKGLDYLHS--ERKIHRDIKAANVLL
Kinase AqueK188.AA YSK 940-968 41 3.6e-07 17.26 In-house 229-257 (257) Show / Hide 
Range on Protein: 940-968
Range on HMM: 229-257/257
Sequence Identity: 41% (12 aa)

NLVNFVEMTLAVEPKDRASANALLHHLYI
.. .|||. |  .|..| ||  || |  |
MFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK188.AA PAKA 939-968 36 4.2e-07 21.15 In-house 231-260 (260) Show / Hide 
Range on Protein: 939-968
Range on HMM: 231-260/260
Sequence Identity: 36% (11 aa)

PNLVNFVEMTLAVEPKDRASANALLHHLYI
... .|..  | |....||||  |||| ..
QEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK188.AA CDKL 733-759 51 4e-06 16.79 In-house 107-131 (286) Show / Hide 
Range on Protein: 733-759
Range on HMM: 107-131/286
Sequence Identity: 51% (14 aa)

ILKALDYLHTLPNPVIHRDVKPSNVLI
||||....|   . .||||.|| | ||
ILKAINFCHK--HNCIHRDIKPENILI
Kinase AqueK188.AA STE 939-968 31 4e-06 17.87 In-house 328-359 (359) Show / Hide 
Range on Protein: 939-968
Range on HMM: 328-359/359
Sequence Identity: 31% (10 aa)

PNLVNFVEMTLAVEPKDRASANALLH--HLYI
|.. .|..  |  .|..|..|. ||.  |  |
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK188.AA STE20 733-766 41 1.1e-05 17.11 In-house 126-157 (288) Show / Hide 
Range on Protein: 733-766
Range on HMM: 126-157/288
Sequence Identity: 41% (14 aa)

ILKALDYLHTLPNPVIHRDVKPSNVLIKMSCGCQ
.|..|||||   | .||||.|  |.|. ..  ..
VLQGLDYLHS--NHIIHRDIKADNILLTEDGEVK
Kinase AqueK188.AA STE20 939-968 36 1.2e-05 16.88 In-house 259-288 (288) Show / Hide 
Range on Protein: 939-968
Range on HMM: 259-288/288
Sequence Identity: 36% (11 aa)

PNLVNFVEMTLAVEPKDRASANALLHHLYI
|.. .||.  | ..|..|..|  ||.| .|
PEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK188.AA CMGC 934-968 21 0.000182 9.57 In-house 473-513 (513) Show / Hide 
Range on Protein: 934-968
Range on HMM: 473-513/513
Sequence Identity: 21% (9 aa)

FSE-------VNPNLVNFVEMTLAVEPKDRASANALLHHLYI
| .        .| ......  |  .|..| .|   | | |.
F-NHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase AqueK188.AA PAKA 733-761 37 0.000244 11.31 In-house 112-138 (260) Show / Hide 
Range on Protein: 733-761
Range on HMM: 112-138/260
Sequence Identity: 37% (11 aa)

ILKALDYLHTLPNPVIHRDVKPSNVLIKM
.|..|...|   . .||||.|  |.|. |
CLQGLEFIHS--KHRIHRDIKSDNILLGM
TyrKc AqueK188.AA TyrKc 614-966 14 0.000272 -153.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 614-966
Range on HMM: 1-280/280
Sequence Identity: 14% (58 aa)

LPHTRVIREGGNGLILEVTFEGATYAVKKTA------LRWREILIMPKL--HHPNVLNLISMMIG--------YPI-------------DLFPRQRHVFH
.   ... ||  | . . |    . |||.        .. ||. || ||  ||||...|.   .          |.             |   . |.   
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

FYSRMTNDLGRSVGSYERFCLRSLNERYKNEPLLLKKIDNNFKHLFSS-ILKALDYLHTLPNPVIHRDVKPSNVLIKMSCGCQNPLICVCVTKPQIMLSD
                                     . .  .. |.  | .  .|||    ..||||    |.|..                 ..  ||
-------------------------------------LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH--------------TVKISD

FDASLELNSD-NSMKPDPPKNSLRDFHLSADRTYHVS--PVGT--IGFK--SPEGFMYMITNDASLLGDMTTKTDIFSFGMLVCLVLLNEEGPKFLNQIG
|  | .. .| ..                .. .|...    |   .  .  .|| ..| .          |||.|..|||  ..  ..   ..   ..| 
FGLSRDIYDDDQQG--------------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF---------TTKSDVWSFGV-CMWEIFTYGQQPYPGMIQ

TLLLSAQQSKHIAVNQLDEMKRKILQKN----GVMYFREREPRVTDKDIFKILPIVRLKQFFSEVNPNLVNFVEMTLAVEPKDRASANALLHHL
   .|.|.    ....... .|    .|                                |  .  . . .  ..  . .|.|| . ... . .
Q-MMSNQE----VIEYVKQGYRMPQPPNDYPMS---------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK188.AA CDKL 934-968 22 0.000645 9.28 In-house 251-286 (286) Show / Hide 
Range on Protein: 934-968
Range on HMM: 251-286/286
Sequence Identity: 22% (8 aa)

FSEVN-PNLVNFVEMTLAVEPKDRASANALLHHLYI
..... . . .|... |   | .| ..  |.|| | 
YPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase AqueK188.AA Pkinase 930-968 23 0.000745 14.71 Pfam 256-293 (293) Show / Hide 
Range on Protein: 930-968
Range on HMM: 256-293/293
Sequence Identity: 23% (9 aa)

LKQFFSEVNPNLVNFVEMTLAVEPKDRASANALLHHLYI
.. |  ......  |..  |.. ||.| .|  .|.| ..
HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK188.AA STE7-Unclassified 939-968 22 0.002207 7.9 In-house 271-301 (301) Show / Hide 
Range on Protein: 939-968
Range on HMM: 271-301/301
Sequence Identity: 22% (7 aa)

PNLVNFVEMTLAVEPKDRASANALLH-HLYI
... .|..  .. .|..|... .||. |  |
KEFMDFISKCCKKHPRERPDIHQLLNEHPWI
Kinase AqueK188.AA STE-Unique 934-968 34 0.017821 3.93 In-house 582-616 (616) Show / Hide 
Range on Protein: 934-968
Range on HMM: 582-616/616
Sequence Identity: 34% (12 aa)

FSEVNPNLVNFVEMTLAVEPKDRASANALLHHLYI
..   | .. | |  |  .| .|.||  ||||.  
PPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase AqueK188.AA CDKL 639-665 48 0.030897 3.45 In-house 40-64 (286) Show / Hide 
Range on Protein: 639-665
Range on HMM: 40-64/286
Sequence Identity: 48% (13 aa)

AVKKTALRWREILIMPKLHHPNVLNLI
.|||.|.  ||| .   |.|.|  |||
MVKKIAM--REIKMLKQLKHENIVNLI
Kinase AqueK188.AA Pkinase 641-668 37 0.039563 8.61 Pfam 41-69 (293) Show / Hide 
Range on Protein: 641-668
Range on HMM: 41-69/293
Sequence Identity: 37% (11 aa)

KKTALRW-REILIMPKLHHPNVLNLISMM
|. ..|. .|| || .|.|||.. |. ..
KDQTHRRLSEIQIMKRLNHPNIVRLYDWF
Kinase AqueK188.AA STE7 939-968 29 0.07506 2.98 In-house 258-288 (288) Show / Hide 
Range on Protein: 939-968
Range on HMM: 258-288/288
Sequence Identity: 29% (9 aa)

PNLVNFVEMTLAVEPKDRASANALLH-HLYI
| ...||.  |  .|..|..   |.. |  |
PEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
Kinase AqueK188.AA STE20 649-669 33 0.452921 0.02 In-house 54-74 (288) Show / Hide 
Range on Protein: 649-669
Range on HMM: 54-74/288
Sequence Identity: 33% (7 aa)

EILIMPKLHHPNVLNLISMMI
||.|| ...|||. . .   .
EISIMKQCKHPNIVKYYGSYL