Gene AqueK187 (A.queenslandica)
AqueK187
Species: A.queenslandica
Alias: AqueK187
External Links:
Annotation:
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK187.AA | Protein | None | 998 | None | Fasta, JSON |
| AqueK187.kin_dom | Protein Kinase Domain | None | 309 | None | Fasta, JSON |
Protein domains of AqueK187.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | AqueK187.AA | S_TKc | 651-992 | 16 | 6.1e-14 | 27.53 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 651-992
Range on HMM: 1-231/231
Sequence Identity: 16% (61 aa)
LPGARVLREGGNGLILEIYYEG--TPYAVKRT-AFRWREILIMPKLHHENILQLTAMLMGPPIEGYPRRRYVYHYYPRMTN---DLGRLIGSYEK-----
|.. .|. | . . .|.|. .||| |. | ||.|| .| . ..| . . || ..| .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF
-YCLRTLKDKFKNEKLLLNKILSNFRFVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTDCDCPNPLACVCRKRPRIVLSDFDASLELATDGTLHPDPP
. . ||........|.|.| . |.|||.||.|||. . .| ..|| . .|
PFPE-HA------------------RFYMYQICCALEYCHSH--GIIHRDLKPENILLDE----------------HIKICDFGLARQL-----------
RSLMTQGFYISSERTYHISPVGTIGFKSPEGFIHMIGNSADVMPVLTT-KADIFSFGLVMLLIVLAEEGPRSMSKMGVLLLSLNTSKMKVDCTPKSPMGT
. .|| . .|| . .. |.|. |.| .. . . | . | ... .
-----------------TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------------
VTITDKDINKILPFHRLKSEFTASLPAVVEFITNSLEIDPEHRPTAKDLLR-------HPFL
| . .|| . |. |||.|||| ..|. ||..
------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | AqueK187.AA | STE | 764-832 | 31 | 3e-13 | 43.27 | In-house | 154-202 (359) | Show / Hide |
Range on Protein: 764-832 Range on HMM: 154-202/359 Sequence Identity: 31% (22 aa) RFVARELLKG-LDYLHTLPNPIVHRDIKPSNILVLTDCDCPNPLACVCRKRPRIVLSDFDASLELATDGT ....|..||| |.||| . |.||||||.|||. . |.|| . |. ... AYICRQILKGLLYYLHSHH--IIHRDIKPANILL-------------------VKLCDFGVCGQLTDSMA |
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| Kinase | AqueK187.AA | CMGC | 672-821 | 19 | 1.8e-12 | 36.36 | In-house | 38-248 (513) | Show / Hide |
Range on Protein: 672-821 Range on HMM: 38-248/513 Sequence Identity: 19% (42 aa) GTPYAVKRTA---FRW----------------REILIMPKL-----------------HHENILQLTAMLMGPPIEGYPRR---------RYVYHYYPRM . .|.|. . . ||| |. .| ||.||..| ... . .|. . ...| | NEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM TNDLGRLIGSYEKY----CLRTLKDKF----------KNEKLLLNKILSNFRFVARELLKGLD--YLHTLPNPIVHRDIKPSNILVLTDCDCP------- .|| ..| .. .. . |.. | | ... | .. .|.||. |.| . |.|||.||.|||. .|... DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HI---R-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKS -NPLACVCRKRPRIVLSDF . . ..| |. |. . || ED-W-NPCQKNGRLKICDF |
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| Kinase | AqueK187.AA | STE-Unique | 766-795 | 53 | 7.7e-12 | 37.78 | In-house | 408-437 (616) | Show / Hide |
Range on Protein: 766-795 Range on HMM: 408-437/616 Sequence Identity: 53% (16 aa) VARELLKGLDYLHTLPNPIVHRDIKPSNIL .....|.||.|||. |||.|||.||.||. YTYQILEGLEYLHSQHNPIIHRDLKPHNIF |
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| Kinase | AqueK187.AA | Ciliate-E2 | 764-897 | 20 | 1.2e-11 | 36.25 | In-house | 163-286 (365) | Show / Hide |
Range on Protein: 764-897
Range on HMM: 163-286/365
Sequence Identity: 20% (33 aa)
RFVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTDCDCPNPLACVCRKRPRIVLSDFDASLELATDGT--LHPDPPRSLMTQGF--------YISSERT
.| .......| ||| | |.||||||.|||. | ..|| | .. .| .| . . .... . |..
EFYIACIILALEYLHSKNN-IIHRDIKPENILF-------------------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD----
YHISPV-----------GTIGFKSPEGFIHMIGNSADV----MPVLTTKADIFSFGLVM
|| |...|| .... . ..|.||.|.| ..
-----QIIQQNMFNTICGTPGYMAPE----ILNGKKYDNQQKQKGYDYKCDIWSLGVIL
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| Kinase | AqueK187.AA | STE | 967-992 | 50 | 3.9e-11 | 35.69 | In-house | 332-359 (359) | Show / Hide |
Range on Protein: 967-992 Range on HMM: 332-359/359 Sequence Identity: 50% (14 aa) EFITNSLEIDPEHRPTAKDLLR--HPFL .|| . |..||..||||..||. |||. DFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | AqueK187.AA | Pkinase | 764-897 | 19 | 1.2e-10 | 38.67 | Pfam | 111-202 (293) | Show / Hide |
Range on Protein: 764-897 Range on HMM: 111-202/293 Sequence Identity: 19% (26 aa) RFVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTDCDCPNPLACVCRKRPRIVLSDFDASLELATDGTLHPDPPRSLMTQGFYISSERTYHISPVGTIG .|.....|.||.|.| |.|||.||.|||. ..... .. ..|| . . | ... .... .||.. KFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDA----------CVKICDFGLAKQFD------------------Y-NNS-MTTF--CGTPW FKSPEGFIHMIGNSADVM--PVLTTKADIFSFGLVM . .|| .. . ..|.|..|.|... YMAPEV----------IRGGQYYGPKVDMWSCGCIL |
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| Kinase | AqueK187.AA | STE20 | 967-992 | 53 | 2e-10 | 34.62 | In-house | 263-288 (288) | Show / Hide |
Range on Protein: 967-992 Range on HMM: 263-288/288 Sequence Identity: 53% (14 aa) EFITNSLEIDPEHRPTAKDLLRHPFL .|. . |..||| ||||..||.|||. DFVDKCLQKDPEKRPTASQLLKHPFI |
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| Kinase | AqueK187.AA | MKC | 765-799 | 51 | 4e-10 | 34.34 | In-house | 106-138 (260) | Show / Hide |
Range on Protein: 765-799 Range on HMM: 106-138/260 Sequence Identity: 51% (18 aa) FVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTD .|..|.|.||.||| . |||||.| .|| . || YVCKEMLQGLMYLHE--HNIVHRDLKSANIMMNTD |
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| Kinase | AqueK187.AA | YSK | 967-992 | 53 | 6.1e-10 | 25.75 | In-house | 232-257 (257) | Show / Hide |
Range on Protein: 967-992 Range on HMM: 232-257/257 Sequence Identity: 53% (14 aa) EFITNSLEIDPEHRPTAKDLLRHPFL ||. |. |||.||.||.|| | | EFVECCLNKDPEQRPSAKELLKHKFI |
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| Kinase | AqueK187.AA | YSK | 768-796 | 58 | 7.7e-10 | 25.44 | In-house | 106-132 (257) | Show / Hide |
Range on Protein: 768-796 Range on HMM: 106-132/257 Sequence Identity: 58% (17 aa) RELLKGLDYLHTLPNPIVHRDIKPSNILV ||.|||||||| . .||||| |.|. REILKGLDYLHS--ERKIHRDIKAANVLL |
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| Kinase | AqueK187.AA | MST | 968-992 | 48 | 9e-10 | 27.16 | In-house | 230-254 (254) | Show / Hide |
Range on Protein: 968-992 Range on HMM: 230-254/254 Sequence Identity: 48% (12 aa) FITNSLEIDPEHRPTAKDLLRHPFL |. | ..|| |.||..|| ||| FVCKCLQKNPEQRWTAEQLLQHPFI |
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| Kinase | AqueK187.AA | STE11 | 967-992 | 50 | 2.5e-09 | 30.18 | In-house | 278-303 (303) | Show / Hide |
Range on Protein: 967-992 Range on HMM: 278-303/303 Sequence Identity: 50% (13 aa) EFITNSLEIDPEHRPTAKDLLRHPFL .|. . .|.||. |||| .||.|||. DFLRHCFEHDPKKRPTANQLLQHPFI |
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| Kinase | AqueK187.AA | MKC | 968-992 | 52 | 3.6e-09 | 30.76 | In-house | 236-260 (260) | Show / Hide |
Range on Protein: 968-992 Range on HMM: 236-260/260 Sequence Identity: 52% (13 aa) FITNSLEIDPEHRPTAKDLLRHPFL |... |. ||. |||| ||.|||. FLWQCLQMDPHKRPTAEQLLKHPFI |
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| Kinase | AqueK187.AA | STE11-Unclassified | 767-796 | 50 | 1.1e-08 | 26.96 | In-house | 113-140 (308) | Show / Hide |
Range on Protein: 767-796 Range on HMM: 113-140/308 Sequence Identity: 50% (15 aa) ARELLKGLDYLHTLPNPIVHRDIKPSNILV ....|.||.||| . |.|||||. |||. TKQILEGLAYLHS--HGIIHRDIKGANILI |
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| Kinase | AqueK187.AA | MST | 771-796 | 57 | 1.5e-08 | 23.23 | In-house | 107-130 (254) | Show / Hide |
Range on Protein: 771-796 Range on HMM: 107-130/254 Sequence Identity: 57% (15 aa) LKGLDYLHTLPNPIVHRDIKPSNILV |.||.||| | ..|||||. |||. LQGLQYLHD--NKKIHRDIKAGNILL |
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| Kinase | AqueK187.AA | STE11-Unclassified | 967-992 | 50 | 1.6e-08 | 26.4 | In-house | 283-308 (308) | Show / Hide |
Range on Protein: 967-992 Range on HMM: 283-308/308 Sequence Identity: 50% (13 aa) EFITNSLEIDPEHRPTAKDLLRHPFL .|. ..|||. |||| || |||. DFLRKCFQIDPKKRPTANQLLQHPFI |
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| Kinase | AqueK187.AA | STE20 | 765-802 | 52 | 3.7e-08 | 26.24 | In-house | 121-156 (288) | Show / Hide |
Range on Protein: 765-802 Range on HMM: 121-156/288 Sequence Identity: 52% (20 aa) FVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTDCDC .. ||.|.|||||| | |.||||| |||. .| .. YICREVLQGLDYLHS--NHIIHRDIKADNILLTEDGEV |
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| Kinase | AqueK187.AA | CMGC | 966-992 | 33 | 4.5e-08 | 21.65 | In-house | 487-513 (513) | Show / Hide |
Range on Protein: 966-992 Range on HMM: 487-513/513 Sequence Identity: 33% (9 aa) VEFITNSLEIDPEHRPTAKDLLRHPFL .... . |..||. |.||.. |.||.. IDLLKKMLQYDPDKRITAEQALQHPYF |
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| Kinase | AqueK187.AA | STE-Unique | 962-992 | 45 | 5.4e-08 | 23.88 | In-house | 586-616 (616) | Show / Hide |
Range on Protein: 962-992 Range on HMM: 586-616/616 Sequence Identity: 45% (14 aa) LPAVVEFITNSLEIDPEHRPTAKDLLRHPFL .| ..|| .|| .| |||.|..||.|..| QPEQQQFIEKCLERNPHHRPSAHQLLHHFWL |
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| Kinase | AqueK187.AA | STE11 | 768-800 | 48 | 2e-07 | 23.21 | In-house | 123-153 (303) | Show / Hide |
Range on Protein: 768-800 Range on HMM: 123-153/303 Sequence Identity: 48% (16 aa) RELLKGLDYLHTLPNPIVHRDIKPSNILVLTDC . .|.|| ||| . |.|||||. |||. .|. KQILEGLQYLHS--HGIIHRDIKGANILLDSDG |
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| Kinase | AqueK187.AA | Ciliate-E2 | 973-992 | 42 | 3e-06 | 17.56 | In-house | 345-365 (365) | Show / Hide |
Range on Protein: 973-992 Range on HMM: 345-365/365 Sequence Identity: 42% (9 aa) LEIDPEHRPT-AKDLLRHPFL |. ||| |.| ....| ||.. LQKDPEKRITGWEQILNHPWF |
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| Kinase | AqueK187.AA | Pkinase | 945-992 | 20 | 8.6e-05 | 18.03 | Pfam | 227-293 (293) | Show / Hide |
Range on Protein: 945-992 Range on HMM: 227-293/293 Sequence Identity: 20% (14 aa) INKILPFHRLKSEFTASL-------------------PAVVEFITNSLEIDPEHRPTAKDLLRHPFL |..|.. .... . .. .||.. |. ||. ||||...| ||.. ICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| TyrKc | AqueK187.AA | TyrKc | 622-992 | 17 | 0.000286 | -153.6 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 622-992
Range on HMM: 1-280/280
Sequence Identity: 17% (69 aa)
LEAFDTAGQCFYGDNIKFFSGKVYTQPNALPGARVLREGGNGLILEIYYEGTPYAVKRTA------FRWREILIMPKL--HHENILQLTAMLMGPPIEGY
.. .. | ...| . . |. . .. ||| |. ||. || || ||.||..| . . . .
ITLGKKLGEGAFG---EVYKGTWK---------------------------IQVAVKMLKEDAREDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRN-F
---PRRRYVYHYYPRMTNDLGRLIGSYEKYCLRTLKDKFKNEKLLLNKILSNFRFVARELLKGLDYLHTLPNPIVHRDIKPSNILVLTDCDCPNPLACVC
. | | | || . .... | .| | .| . .| .||| ...|||. |.|| .
MYIEPLMIVMEYMPH--GDLKDYLRKHRPK--------------LCMKDLLSF---CWQIACGMEYLHSK--NCIHRDLAARNCLVGENH----------
RKRPRIVLSDFDASLELATD---GTLHPDPPRSLMTQGFYISSERTYHIS--PVGT--IGFK--SPEGFIHMIGNSADVMPVLTTKADIFSFGLVML-LI
.. ||| | .. | | |. .|. . | . . .|| . . . ||| |..||| .| .
----TVKISDFGLSRDIYDDDQQG-----------------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGK---------FTTKSDVWSFGVCMWEIF
VLAEEGPRSMSK--MGVLLLSLNTSKMKVDCTPKS--PMGTVTITDKDINKILPFHRLKSEFTASLPAVVEFITNSLEIDPEHRPTAKDLLRHPFL
. .. . | . | . . . . |.. || | ... . .. . ||| ||| ... | ..
TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
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| Pkinase | AqueK187.AA | Pkinase | 667-701 | 34 | 0.149363 | 6.57 | Pfam | 31-65 (293) | Show / Hide |
Range on Protein: 667-701 Range on HMM: 31-65/293 Sequence Identity: 34% (12 aa) EIYYEGTPYAVKRTAFRWREILIMPKLHHENILQL .| .... ...|..| .|| || .|.|.||..| IIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRL |
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