AqueK182

Species: A.queenslandica
Alias: AqueK182
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK8

Sequence

Name Sequence Type Origin Length Description Download
AqueK182.AA Protein None 162 None Fasta, JSON
AqueK182.kin_dom Protein Kinase Domain None 83 None Fasta, JSON

Protein domain

Protein domains of AqueK182.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK182.AA NEK8 59-141 58 1.6e-51 145.28 In-house 1-85 (278) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-85/278
Sequence Identity: 58% (50 aa)

YERIKTVGKGAYGQAILYKRKEDE--SLVILKQINILELNKIERQNVVTEIKILAMLDHPHIISYYDNFEEDGLMMIEMEFADGG
|||| .||.|| | ..|| ||||   .|||.||||  .. . |||    || .|.||.|| ||||||.|.||.  ||||| ||||
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGG

Kinase AqueK182.AA NEK 59-141 35 2.3e-36 125.72 In-house 1-92 (286) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-92/286
Sequence Identity: 35% (33 aa)

YERIKTVGKGAYGQAILYKRKEDESL-----VILKQINILELNKIERQNVV-TEIKILAMLDHPHIISYYDNFEEDG--LMMIEMEFAD-GG
||.||..|.|..|.. ...||.|..      ...|.||. ...  |.|| .  |..||..|.||.|..||| |.|..   ..|.||... ||
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGG

Kinase AqueK182.AA NEK1 59-141 41 9.3e-29 96.96 In-house 1-85 (276) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-85/276
Sequence Identity: 41% (35 aa)

YERIKTVGKGAYGQAILYKRKEDESLVILKQINILELNKIERQNVVTEIKILAMLDHPHIISYYDNFEEDGL--MMIEMEFADGG
|..||..|.|..| |.| |.||| ..  .| ||. .  . ||.... | .|||...|| |..|.. ||| |     | ||..|||
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGG

Kinase AqueK182.AA Pkinase 59-141 28 1.2e-17 63.53 Pfam 1-85 (293) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-85/293
Sequence Identity: 28% (24 aa)

YERIKTVGKGAYGQAILYKRKEDESLVILKQINILELNKIERQNVVT--EIKILAMLDHPHIISYYDNFEEDGLMMIEMEFADGG
|......|.|..|.  . ..| .. .| .|.|.  . .. ..|. .   ||.|...|.||.|. .|| ||... . . ||...||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGG

Kinase AqueK182.AA NEK4 59-141 32 2.7e-17 58.82 In-house 1-85 (257) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-85/257
Sequence Identity: 32% (28 aa)

YERIKTVGKGAYGQAILYKRKEDESLVILKQINILELNKIERQNVVTEIKILAMLDHPHIISYYDNFE-EDG-LMMIEMEFADGG
|. .| |||| ||   | . . |    ..| .. ..  . ||.    |...|  | || |..| . .| |.| .. | | | .||
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGG

Kinase AqueK182.AA ULK 59-141 26 2.3e-15 50.14 In-house 1-105 (329) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-105/329
Sequence Identity: 26% (28 aa)

YERIKTVGKGAYGQAILYKRK-EDE-----SLVILKQINILELNKIERQN--------VVTEIKILAMLD--------HPHIISYYDNFEEDGL--MMIE
|. ..  |||..|    || . ..       .|. |.| . ..|... ..        .  ||||. .|.        ||.|. .|| ||..      | 
YCLNHCLGKGSFG--KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

MEFADGG
||. .||
MEYCNGG

Kinase AqueK182.AA CAMKL 59-141 25 5.4e-15 44.14 In-house 1-106 (297) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-106/297
Sequence Identity: 25% (27 aa)

YERIKTVGKGAYGQAILYKR-KEDESLVILKQIN--ILELNKIERQN-----------VVTEIKILAMLD---HPHIISYYDNFEEDGL------MMIEM
|. .|| |||..|.  | .  .  .  |  | |.   . .. . ..|           .  ||.|. ||.   ||.||. |. .| .        . . |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFADGG
| ..||
EYCSGG

Kinase AqueK182.AA NuaK 59-141 39 7.3e-15 34.98 In-house 1-84 (252) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-84/252
Sequence Identity: 39% (34 aa)

YERIKTVGKGAYGQAILYKRKEDESLVILKQINILELNKIERQN----VVTEIKILAMLDHPHIISYYDNFEEDGLMMIEMEFADGG
|| .|| ||| ||   |   ..   .|  | |     .||| ..    .  ||.|.  |.|||||. |  ||    . | ||.| ||
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSI---KKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGG

Kinase AqueK182.AA Ciliate-A9 59-141 25 1.5e-14 30.27 In-house 1-106 (392) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-106/392
Sequence Identity: 25% (28 aa)

YERIKTVGKGAYGQAILYKRKE--DESLVILKQINILELNK--IERQNVVTEIKILAMLDHPHIISYY---------------------DNFEEDGLMMI
.| ||  |.||.|. |  . .   |....  | |.   . .  ||.|    |.|||  .|||.|. .                        .| |   .|
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQ--EAKILQQHDHPNIVKFKNIKNINTQKETKQLNYIFQISKFCESDQNIHI

EMEFADGG
 ||. ..|
VMEYMKCG

Kinase AqueK182.AA ULK 59-141 27 1.7e-14 47.91 In-house 1-102 (324) Show / Hide
Range on Protein: 59-141
Range on HMM: 1-102/324
Sequence Identity: 27% (28 aa)

YERIKTVGKGAYGQAILYKRK-EDE----SLVILKQINILELNKIERQ--------NVVTEIKILAMLD---HPH--IISYYDNFEEDGL--MMIEMEFA
|. ..  |||..|    || . ..      .|  |.|.. ..||.. .        .   ||.|. .|.   ||.  |. .|| ||..      | ||. 
YCLNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

DGG
.||
NGG

Kinase AqueK182.AA NEK6 59-149 32 1.2e-12 37.65 In-house 1-92 (252) Show / Hide
Range on Protein: 59-149
Range on HMM: 1-92/252
Sequence Identity: 32% (30 aa)

YERIKTVGKGAYGQAILYKRKEDESLVILKQINILEL-NKIERQNVVTEIKILAMLDHPHIISYYDNFEEDGLMMIEMEFADGGYKANLIKY
..  | .||| .      .   |.  | ||.. | |.  .  ||  . || .|  |.||..| ||. | |.  . | .| || |  . .||.
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKH