Gene AqueK181 (A.queenslandica)
AqueK181
Species: A.queenslandica
Alias: AqueK181
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
AqueK181.AA | Protein | None | 111 | None | Fasta, JSON |
AqueK181.kin_dom | Protein Kinase Domain | None | 108 | None | Fasta, JSON |
Protein domains of AqueK181.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | AqueK181.AA | NEK8 | 1-109 | 55 | 3.5e-82 | 234.41 | In-house | 144-256 (278) | Show / Hide |
Range on Protein: 1-109 Range on HMM: 144-256/278 Sequence Identity: 55% (63 aa) DLKTANIFLTRH-GIVKLGDFGISKVLSGTHQAADS--IVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPFDGTNLPALVHKIVEG-SFDPI ||||.|||.||| ..||.|||||||... .. . .||||||.|||.||||.|| |||.|.|||.| || || | |...|||||| ||. . . || DLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPI KGKYSDELKQLVS ...|| |...||. SDHYSNEMRMLVH |
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Kinase | AqueK181.AA | NEK | 1-109 | 50 | 9.3e-65 | 221.46 | In-house | 144-264 (286) | Show / Hide |
Range on Protein: 1-109 Range on HMM: 144-264/286 Sequence Identity: 50% (61 aa) DLKTANIFLTRHGI----VKLGDFGISKVLSGTHQAADS-IVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCL--SRPFDGT--NLPALVHKIVEG |.|..|||||. .. ||.|||||||||. | ..| . ||||||.|||.|..| ||.|||||||||.| ||..| .||... |.|.|. ||..| DIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG -SFDPIKGK--YSDELKQLVS ..|| . ||..|..|.| PQYPPIPSHRMYSQDLQNLIS |
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Kinase | AqueK181.AA | NEK1 | 1-109 | 48 | 1.9e-53 | 183.73 | In-house | 129-254 (276) | Show / Hide |
Range on Protein: 1-109 Range on HMM: 129-254/276 Sequence Identity: 48% (61 aa) DLKTANIFLT--RHG---------------IVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPFDGTNLPA |.|. ||||| . | .||||||||...|. | | .|||||.|||||. | || |||||||||.| | . |..||.. |... DIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKN LVHKIVEGSFDPIKGKYSDELKQLVS || ||..|.. || || ||. ||| LVLKICQGTYPPIPPHYSYELQSLVS |
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Kinase | AqueK181.AA | NEK4 | 1-108 | 48 | 8.8e-42 | 145.13 | In-house | 127-234 (257) | Show / Hide |
Range on Protein: 1-108 Range on HMM: 127-234/257 Sequence Identity: 48% (52 aa) DLKTANIFLTRHGIVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPFDGTNLPALVHKIVEGSFDPIKGKY |||| |||||. |.|.||||||.|| . | ..|||||.|||. . |. ||||||||| . ||. | || ... |...|..| |. .| DLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNY SDELKQLV | .|..|| SQDLQNLV |
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Kinase | AqueK181.AA | NEK2 | 1-109 | 35 | 3.1e-38 | 126.26 | In-house | 150-297 (319) | Show / Hide |
Range on Protein: 1-109 Range on HMM: 150-297/319 Sequence Identity: 35% (52 aa) DLKTANIFLTRHGI---------------------------------------VKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWS |.| ||||| . ||||||| ..| . | . |||||| ||| .| || |||||| DIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWS LGCILHEMMCLSRPFDGTNLPALVHKIVEGSFDPIKGKYSDELKQLVS .||.. || |. || .|| .| || .| |..| ||..| ... VGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIH |
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Kinase | AqueK181.AA | NEK6 | 1-109 | 50 | 5.7e-35 | 112.35 | In-house | 128-239 (252) | Show / Hide |
Range on Protein: 1-109 Range on HMM: 128-239/252 Sequence Identity: 50% (57 aa) DLKTANIFLTRHGIVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPF--DGTNLPALVHKIVEGSFDPIKG |.| ||.|.| .||||||| |. . | || |.||||||.||| . . || |||||||||.| || | || | || .| .|| . . |. . DIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPA -KYSDELKQLVS ||..|.|||. DHYSEQLRQLVC |
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Kinase | AqueK181.AA | NEK-Unclassified | 1-108 | 40 | 6.6e-34 | 109.42 | In-house | 122-235 (258) | Show / Hide |
Range on Protein: 1-108 Range on HMM: 122-235/258 Sequence Identity: 40% (46 aa) DLKTANIFLTRHGIVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPFDGTNLPALVHKIVEGSF------D |||. ||||| .| .||||||... | | |||. ..|||.|. . || .||.||||||. || || |. . ||. . . DLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALE PIKGKYSDELKQLV |. || | |.. PVSKTYSTDLQQVI |
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Kinase | AqueK181.AA | Pkinase | 1-110 | 25 | 4.4e-30 | 107.45 | Pfam | 133-272 (293) | Show / Hide |
Range on Protein: 1-110 Range on HMM: 133-272/293 Sequence Identity: 25% (36 aa) DLKTANIFLTRHGIV----KLGDFGISKVL-SGTHQAADSIVGTPYYISPEICE-GKQYNSKSDIWSLGCILHEMMCLSRPFDGT------NLPALVHKI ||| .||.. ..| . |..|||..|.. . .....|||.|..||.. |. | .|.|.||.||||.||.| ||.| . ... .| DLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI VEGSFDPIKGKYS--------------------DELKQLVSG .. .. . . .|.|..... MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW |
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Kinase | AqueK181.AA | ULK | 1-110 | 25 | 4.1e-29 | 98.81 | In-house | 155-308 (329) | Show / Hide |
Range on Protein: 1-110 Range on HMM: 155-308/329 Sequence Identity: 25% (39 aa) DLKTANIFLTRH------------GIVKLGDFGISKVLSGT---HQAADSIV------GTPYYISPEICE----GKQYN-SKSDIWSLGCILHEMMCLSR |.| .|| .. . |..|..||| .|... | . . | |||.| .|.| . .|.|. .|.||||||||..|| DIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKP PFDGTNLPALVHKIVEGSFD------------PIK-------GKYSDELKQLVSG || . ....|.. .. |.. . |.|.|.| .. PFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRR |
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Kinase | AqueK181.AA | NEK11 | 1-104 | 46 | 2.9e-27 | 96.31 | In-house | 130-232 (259) | Show / Hide |
Range on Protein: 1-104 Range on HMM: 130-232/259 Sequence Identity: 46% (48 aa) DLKTANIFLTRHGIVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLSRPFDGTNLPALVHKIVEGSFDPIKGKY ||| |||| . ..|.||||.|..| | . | . ||| |.||| . | .||||||| ||| || |. | | | ..| .|||| . .| DLKSKNIFL-KNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMDHAFAGSNFLSIVLNIVEGDTPSLPDRY SDEL || PREL |
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Kinase | AqueK181.AA | ULK | 1-110 | 25 | 1.6e-26 | 91.17 | In-house | 151-303 (324) | Show / Hide |
Range on Protein: 1-110 Range on HMM: 151-303/324 Sequence Identity: 25% (40 aa) DLKTANIFLTR------------HGIVKLGDFGISKVLSGT---HQAADSIV------GTPYYISPEICE----GKQYN-SKSDIWSLGCILHEMMCLSR |.| .|| .. .|..|..||| .|.. | ..| |||.| .|.| . .|.|. .|.||||||||..|| . DIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKY PFDGTNLPALVHK--------------IVEGSFDPIKG----KYSDELKQLVSG || . .... | ... |. | |.|.|.| .. PFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRR |
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Kinase | AqueK181.AA | Pkinase_Tyr | 6-78 | 22 | 6e-06 | 20.82 | Pfam | 141-218 (270) | Show / Hide |
Range on Protein: 6-78 Range on HMM: 141-218/270 Sequence Identity: 22% (18 aa) NIFLTRHGIVKLGDFGISKVL-----SGTHQAADSIVGTPYYISPEICEGKQYNSKSDIWSLGCILHEMMCLS-RP-FDG |. .|. ..|| .||| .. . .... .. . . . .|| . ...|||.|| | . |.. . | . | NCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM-APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG |
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Kinase | AqueK181.AA | S_TKc | 1-111 | 14 | 2.3e-05 | -98.23 | SMART | 1-220 (231) | Show / Hide |
Range on Protein: 1-111 Range on HMM: 1-220/231 Sequence Identity: 14% (35 aa) D--------------------------------------------------------------------------------------------------- YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM -------------------LKTANIFLTRHGIVKLGDFGISKVLSGTHQAADSIVGTPYYISPEICEGKQYNS-KSDIWSLGCILHEMMCLSRPFDGTNL || .||.|.. .|..|||....| ....|||.|..||.. .|. |.|.||.|||| ||.| ||. .. YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM PALVHKIVEGSFDPIKGKYSDELKQLVSG---------------E .. .||. |.|.|..... . QMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTAEALQ |