Gene AqueK179 (A.queenslandica)

AqueK179

Species: A.queenslandica
Alias: AqueK179
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK2

Sequence

Name Sequence Type Origin Length Description Download
AqueK179.AA Protein None 349 None Fasta, JSON
AqueK179.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of AqueK179.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK179.AA NEK2 9-270 44 2.4e-146 492.47 In-house 1-319 (319) Show / Hide 
Range on Protein: 9-270
Range on HMM: 1-319/319
Sequence Identity: 44% (142 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHRHQRKL
| | . ||.||||.|.|.||. |||.||||||.| .|.| |.|.|| |.|.||.|||  ||.|||.|||| .| |||. ||| ||||. .|.  | .|. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

LPECFIWQVMHQILLALEECHR-------------SKENVGG--KVMHRDIKPANVFLDGEGQ-------------------------------------
..| ||| .| |...|| |||.              |  . |   ..||||||||.||| ..                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKLGDFGLARILH-NTSLAKTFVGTPYYMSPEQYSCNSYDHRSDLWSIGCLLYELCALKPPFVASSQYKLAEYVCNGRFSRIPSKYSDDLHWTISQLL
  ||||||||||.|   || |.||||||||||||| .. .|. .|| ||.|||.||.|||.||| | .|  |.| . .|.|.|||. ||..|   |.  .
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

HVKPEKRPLLSQLL--SLL
 |....||    .|  ...
NVDHYHRPSIEEILQHPQI
Kinase AqueK179.AA NEK 9-272 41 6.00000000001e-129 434.69 In-house 1-286 (286) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-286/286
Sequence Identity: 41% (120 aa)

YVVVGMIGSGSFGQCKKIRRICDGKV-----LVWKEINYKEMTESEKQQLV-TEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCP-GGDLATL---
| .. .||.||||.. |.||. |||.     .|||.||...|.| |||...  ||..|..||| .|| |||..|..  ..|.|. |||  ||||. .   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

ISQHRHQRKLLPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGEGQ----VKLGDFGLARILHNT-SLAKT-FVGTPYYMSPEQYSCN
| ......|...|  || .. |..||| ..|  | .  .|..||||||.|.||. ..     ||.||||....| .| ..|.| .||||||||||. .  
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

SYDHRSDLWSIGCLLYELCAL--KPPFVAS--SQYKLAEYVCNG-RFSRIPSK--YSDDLHWTISQLLHVKPEKRPLLSQLLSLLEE
.|...|| ||.||.|||.|.|  |.|| |.  ... |.  ...|  ...|||.  ||.||.  |||.|.. ||.||  .|.|..   
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase AqueK179.AA S_TKc 9-277 31 8.9e-77 262.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-277
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPG--GDLATLISQHRHQR
| ..  ||.|.||...| | . .|..   |.|.         ...  |...|.. .| .||..|| . |   . ||...|||.|  ||| ..| ......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--KLLPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGEGQVKLGDFGLARILHNTSLAKTFVGTPYYMSPEQYSCNSYDH-RSDLWSI
  . .||  .. .|.||..||| ||. .      ..|||.||.|..||   ..|..||||||.|      .||.|||.||.||     .|.. ..| ||.
LRFPFPE-HARFYMYQICCALEYCHSHG------IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GCLLYELCALKPPFVASSQYKLAEYVCNGRFSRIPSKYSDDLHWTISQLLHVKPEKRPLLSQLLS--LLEEKIPLA
||.|||... .|||    .... . ..           |...   |...|.. |||||   ..|   ..  . |  
GCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK179.AA NEK8 9-270 31 1.3e-76 218.24 In-house 1-278 (278) Show / Hide 
Range on Protein: 9-270
Range on HMM: 1-278/278
Sequence Identity: 31% (91 aa)

YVVVGMIGSGSFGQCKKIRRICDG--KVLVWKEINYKEMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHRHQR
|  .  .| |.|| |   ||  |.  .  .||.||  .|.|.| |    |...|  | |  |. |||  ..  .  | |  ||..|| |. .| ||.   
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNT--LMIEMEYADGGTLYQMI-QHQQNK

KLLPEC----------------FIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGE-GQVKLGDFGLARILHNTSLAKT---FVGTPYYMSP
....|                  |  .. |...|.   |         . |||.|..|.|..   . ||.||||.. |.   ... |    |||||||||
LFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQH------NILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSP

EQYSCNSYDHRSDLWSIGCLLYELCALKPPFVASSQYKLAEYVCNG-RFSRIPSKYSDDLHWTISQLLHVKPEKRPLLSQLLS--LL
|  .  .|.  || |..|| |||.| ||  | || . .|      .  .  |...|| ...  ....| . ||.|| .||...  |.
EMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase AqueK179.AA NEK1 9-268 39 2.7e-76 259.76 In-house 1-272 (276) Show / Hide 
Range on Protein: 9-268
Range on HMM: 1-272/276
Sequence Identity: 39% (109 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHRHQRKL
|..  .||.||||   . ..  ||...| ||||  .| |.|... . ||..|. .||  ||.|..  . . . .|||. ||| ||||.  | . . . ||
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

LPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLD--GEG---------------QVKLGDFGLARILHNT-SLAKTFVGTPYYMSPEQYS
 .|  | .   || |||   |        |..|||||. |.||     |                ||||||| ||.| .| ..|.| .||||| |||   
FSEDQIMHWFCQICLALNHIHDR------KILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQ

CNSYDHRSDLWSIGCLLYELCALKPPFVASSQYKLAEYVCNGRFSRIPSKYSDDLHWTISQLLHVKPEKRPLLSQLLS
   |.. || || || |||||.|| || | .   |   .| |... ||. || .|.  .||.. . |. ||   |.|.
NKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILE
Kinase AqueK179.AA Pkinase 9-270 28 5.4e-69 240.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-270
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESEKQQLVT--EVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGG----DLATLISQH
|.... |||||||...| ... .||. . |.|....  ....|...   |. ....|.| .||..||   |   . .|...|||.||    ||...||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

RHQRKLL--PECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGEGQV----KLGDFGLARI--LHNTSLAKTFVGTPYYMSPEQYS-CNS
 .... .  .|  .  .| ||| .|| ||.       ...|||.||.|...| .|..    |..|||||.   . | | ..||.|||.||.||    .. 
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YDHRSDLWSIGCLLYELCALKPPFVAS------SQYKLAEYVCNGRFSRIPSKYS--------------------DDLHWTISQLLHVKPEKRPLLSQLL
|....| ||.||.|||..  .|||  .      .|... . .  .....  .. .                    ...   |. .|...|.|||   |.|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

SL--L
    .
QHPWF
Kinase AqueK179.AA STE 9-270 23 2.7e-60 206.63 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-270
Range on HMM: 1-359/359
Sequence Identity: 23% (89 aa)

YVVVGMIGSGSFG-QCKKIRR----IC----------DGKVLVWKEINYKEMT---------------ESEKQQLVTEVNLLRELK--HTHIVQYYDRII
.  ...||.|.||  .|....    |.           |..   |..|... .               ..|.||.  |........  | .||.||.  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DRSQSMLYIITEYCPGGDLATLIS-------QHRHQR---KLLPECFIWQVMHQILLA-LEECHRSKENVGGKVMHRDIKPANVFLDGEGQVKLG
     . . . |.|. ||..|| |  .|        .. |.|   . .||  |  . .||| . |.  |. .      ..||||||||..|     ||| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH------IIHRDIKPANILL-----VKLC

DFGLARILHN---------------TSL--AKTFVGTPYYMSPEQYSC------NSYDHRSDLWSIGCLLYELCALKPPF---VASSQYKLAE-------
|||.. .| .               |.    .|||||| .|.||  ..      . || ..| ||.||.. |..  |||.      . . ..        
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

-----YVCNGRFSRIPS-------------------KYSDDLHWTISQLLHVKPEKRPLLSQLLS----LL
     .. ||   ..|.                   |.|....  |.. |   |.|||  ||||.     .
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK179.AA NEK6 9-263 36 3.1e-58 190.18 In-house 1-252 (252) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-252/252
Sequence Identity: 36% (95 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESE-KQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHRHQRK
. .   || | |    . . . |.|.   | .   || .   .|  . |..||..| | ....||.  |.  .  | |. |    ||.. .|   . |..
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNE--LNIVLELADAGDMSRMIKHFKKQKR

LLPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGEGQVKLGDFGLARIL-HNTSLAKTFVGTPYYMSPEQYSCNSYDHRSDLWSIGCL
|.||  ||.   |.  |||  |        .||||||||||||. ..| ||||| || |    .|  |   ||||||||||    | |  .||.||.|||
LIPERTIWKYFVQLCSALEHMHSK------RVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCL

LYELCALKPPFVASSQ--YKLAEYVCNGRFSRIPS-KYSDDLHWTISQLLHVKPEKRPLL
|||. ||. ||       | | . . .  .  .|.  ||..|   ..  .|  ||.|| .
LYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase AqueK179.AA CAMK 14-268 18 4e-57 182.29 In-house 1-421 (425) Show / Hide 
Range on Protein: 14-268
Range on HMM: 1-421/425
Sequence Identity: 18% (79 aa)

MIGSGSFGQCKKIRRICDG------------KVLVWKEINYKEMT--------------------------ESEKQQLVTEVNLLRE-------LKHTHI
 .|.||||. |. ... ..            .    | |. | ..                          .. ....  |.....        |.| .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYYDRIIDRS-----------------QSMLYIIT---EYCPGG----DLATLISQHRHQR-----------KLLPECFIWQVMHQILLALEECHRSKE
.. |. . |..                 ....|...   |||.||    ||   | .|.. .           . ..|    ....||. |.. ||    
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH--

NVGGKVMHRDIKPANVFLDGE-----------------GQVKLGDFGLARILHN------------------------TSLAKTFVGTPYYMS-PEQYSC
    ...|||.|| |. ||                   ...|. |||.|...                          . . |||.|||.||. ||  . 
----NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

NS--------------YDHRSDLWSIGCLLYELCALKPPFVAS-------------SQYKLAEYVCNGRFSRIPSKYSD---------------------
..              |.  .| ||.|..|| .   .||| ..             ..|.| | ...|... .|.. |.                     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

--DLHWTISQLLHVKPEKRPLLSQLLS
  .    |...| | ||||. ..| |.
SQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase AqueK179.AA NEK4 9-261 35 4.7e-57 195.86 In-house 1-246 (257) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-246/257
Sequence Identity: 35% (91 aa)

YVVVGMIGSGSFGQCKKIRRICDGKVLVWKEINYKEMTESEKQQLVTEVNLLRELKHTHIVQYYDRIIDRSQSMLYIITEYCPGGDLATLISQHRHQRKL
|  .  .| ||.|    .|   |.|  | | .. |.    |..    |..||  |||  ||.| .        .|||.  .| |||| .   | . |  .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQ--F

LPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGEGQVKLGDFGLARILH-NTSLAKTFVGTPYYMSPEQYSCNSYDHRSDLWSIGCLL
|.|  .     || .||   |.       ...||| |  |.||     .|.||||..|.|     .||| .||||||||| ..   ||..||.||.|| .
LEEYQVVEWFVQIAMALQYMHEK------HILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCV

YELCALKPPFVASSQYKLAEYVCNGRFSRIPSKYSDDLHWTISQLLHVKPEKRP
||.  ||  | |     |   . .|.   .| .|| ||   . |.|  .|.|||
YEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRP
Kinase AqueK179.AA ULK 9-260 24 3.2e-56 193.09 In-house 1-317 (329) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-317/329
Sequence Identity: 24% (80 aa)

YVVVGMIGSGSFGQCKKIRRICD----GKVLVWKEINYKEMTESEKQ--------QLVTEVNLLRELK--------HTHIVQYYDRIIDRSQSMLYIITE
|..  ..|.||||.  | | . .    ... . | |  ..| .....        .|  |. ....||        | .||..||   .     .|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPGGDLATLISQHRH------QRKLLPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDGE------------GQVKLGDFGLARILHN
||.|||| ..|.....        | |.|  . |...||| .. | |        ...||||||.|. ..              |..|..|||.|. . |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH------NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN

T----SLAKTFV------GTPYYMSPEQYS----CNSYD-HRSDLWSIGCLLYELCALKPPFVASSQYKLAEYVCNGRFS--------------RIP---
      ...|.|      |||.||.|.  .    .  |. . .|.||.||..||.   ||||.|.  ... .. ..  .               ..|   
DNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG

--SKYSDDLHWTISQLLHVKPEKR
   . |....  |...| .....|
NDPQISPECKDLIRRMLQYDEKDR
Kinase AqueK179.AA ULK 9-260 26 5.8e-55 188.92 In-house 1-312 (324) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-312/324
Sequence Identity: 26% (84 aa)

YVVVGMIGSGSFG-QCKKIRRICD---GKVLVWKEINYKEMTESEKQ--------QLVTEVNLLRELK---HTH--IVQYYDRIIDRSQSMLYIITEYCP
|..  ..|.|||| .  | | . .   ...   | |. |.| .....        .|  |......||   | .  ||..||   .     .|||.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLATLISQHRH-----QRKLLPECFIWQVMHQILLALEECHRSKENVGGKVMHRDIKPANVFLDG------------EGQVKLGDFGLARILHN----
|||| ..| ....       | |.|  . |...||. .. | |        ...||||||.|  .              .|..|..|||.|... |    
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKH------NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

TSLAKTFV------GTPYYMSPEQYS----CNSYD-HRSDLWSIGCLLYELCALKPPFVAS--SQY----KLAEY-------VCNGRF-SRIPS---KYS
  . .|.|      |||.||.|.  .    .  |. . .|.||.||..||.   |.||...  .||    || .        ..|  .  ..|.   | |
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

DDLHWTISQLLHVKPEKR
....  |...| .....|
PECKDLIRRMLQYDEKDR
Kinase AqueK179.AA TyrKc 9-270 20 5.6e-16 35.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-270
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YVVVGMIGSGSFGQ-----------CKKIRRICDGKVLVWKEINYKEMTESEKQQLVTEVNLLREL--KHTHIVQYYDRIIDR-----SQSMLYIITEYC
 .   ..|.| ||.            |...  .                   .. .  | .....|  .| .||. |  ...      .   |.|..||.
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

PGGDLATLISQHRHQRKLLPECFIWQVMHQILLALE--ECHRSKENVGGKVMHRDIKPANVFLDGEGQVKLGDFGLARILHNT--------SLAKTF-VG
|.|||   .  ||..  | .. .. . ..||    |  . .        .. |||.   |. .. ...|| .||||.| ...            |.   |
PHGDLKDYLRKHRPK--LCMKDLL-SFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

TP-----YYMSPEQYSCNSYDHRSDLWSIGCLLYELCAL-KPPFVA-----SSQYKLAEYVCNGRFSRIPSK--------YSDDLHWTISQLLHVKPEKR
.        |.||    . . . || || | ...|.. . ..|         | . . ||| .|.  ..|           .|...  ..|  | .||.|
GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

PLLSQLLSLL
|  |.. ...
PTFSEIHECF
Kinase AqueK179.AA Pkinase_Tyr 46-95 27 6.9e-08 27.34 Pfam 41-94 (270) Show / Hide 
Range on Protein: 46-95
Range on HMM: 41-94/270
Sequence Identity: 27% (15 aa)

TESE--KQQLVTEVNLLREL-KHTHIVQYYDRIIDRSQS-MLYIITEYCPGGDL
....  .. .  |......| .| .||..|  ..|....  .||..||.|.|||
MHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase AqueK179.AA Pkinase_Tyr 148-172 40 0.002477 11.91 Pfam 141-165 (270) Show / Hide 
Range on Protein: 148-172
Range on HMM: 141-165/270
Sequence Identity: 40% (10 aa)

NVFLDGEGQVKLGDFGLARILHNTS
|. .. ...|| .|||||| ..|..
NCLVTENNVVKICDFGLARDIYNDD
Kinase AqueK179.AA Pkinase_Tyr 184-270 28 0.146394 5.91 Pfam 181-270 (270) Show / Hide 
Range on Protein: 184-270
Range on HMM: 181-270/270
Sequence Identity: 28% (26 aa)

MSPE--QYSCNSYDHRSDLWSIGCLLYELCAL-KPP-FVASSQYKLAEYV-CNGRFSRIPSKYSDDLHWTISQLLHVKPEKRPLLSQLLSLL
|.||  .|.   . . || || | |..|.. . . | .   | . . ||.  .|.   .| . .|...  . |  | .||.||  |.... |
MAPECINYGK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL