AqueK156

Species: A.queenslandica
Alias: AqueK156
External Links:
Annotation:

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
AqueK156.AA Protein None 450 None Fasta, JSON
AqueK156.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of AqueK156.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK156.AA Haspin 212-385 28 5e-44 152.58 In-house 88-264 (264) Show / Hide
Range on Protein: 212-385
Range on HMM: 88-264/264
Sequence Identity: 28% (50 aa)

GKYPEFLINAWDNWDEKEESDNDRPDVFSPKQLYVMFAFENSGCALEAF--TFHSKREAMSVLAQIAATLAVGEAALKFEHRDMHRGNILVR-RTKEEKM
||.. .|  .||...  ..| |||||.|.  ||.  . .|. | .|. |   | . ..  |.. |.  ..........|.|.| | ||.|.  .||... 
GKCCKKLNKMWDHYCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWL

VFVIDSHKYVLPSEGVHVTVIDYTLSRLSQGSCTSYNDLNNLPWLFKGHGGIQHDTYLRMRNATKSDWSKFAPRTNA
 . .|  .  ..| || || ||...||.. . ...|.|..|.  .|....  | | | .||.  .. |........ 
HYTMDGKTIKIKSHGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK

Kinase AqueK156.AA Haspin 151-206 37 1e-11 38.52 In-house 1-60 (264) Show / Hide
Range on Protein: 151-206
Range on HMM: 1-60/264
Sequence Identity: 37% (23 aa)

TLQKLGEGVFGEVFSCYTPEGDGLAVKIMPIEGKEL-----INDEKQKTFEEILPEMVISK
  .|.|||..|||||. | .|   ..|| ||..        ...|.|.|..|.|.| .| |
NCKKIGEGCYGEVFSV-TWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMK

Kinase AqueK156.AA DUF3635 351-395 33 2.2e-11 40.83 Pfam 1-56 (121) Show / Hide
Range on Protein: 351-395
Range on HMM: 1-56/121
Sequence Identity: 33% (19 aa)

PWLFKGHG---------GIQHDTYLRMRNATKS--DWSKFAPRTNACWLYYIVNKM
. .| | |           | | |  ||. .|   .||.| |.||  ||.|   |.
HDFFQGKGKSKINEYQYDYQFDIYRMMRKMLKNPICWSQFHPMTNVLWLHYLIHKL

Kinase AqueK156.AA STE 149-197 18 3.9e-07 21.39 In-house 1-77 (359) Show / Hide
Range on Protein: 149-197
Range on HMM: 1-77/359
Sequence Identity: 18% (14 aa)

KRTLQKLGEGVFGEVFSCYTPE----------------GDGLAVKIMPIEGK------------ELINDEKQKTFEE
 . ..|.|.| ||.|. ..  .                |.  |.|.|..| .            | .|.|... ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILK

Kinase AqueK156.AA EGFR 150-204 35 6.2e-07 18.87 In-house 2-54 (258) Show / Hide
Range on Protein: 150-204
Range on HMM: 2-54/258
Sequence Identity: 35% (20 aa)

RTLQKLGEGVFGEVFS-CYTPEGDGLAVKIMPIEGKELINDEKQKTFEEILPEMVI
. ...|| |.|| |.   . ||  |  ||| |.  |.| .   .| .||.| |. .
KKVKVLGSGAFGTVYKGIWIPE--GENVKI-PVAIKVLREQTGPKANEEMLDEAYV

Kinase AqueK156.AA CAMK 154-204 19 1.4e-05 13.17 In-house 1-84 (425) Show / Hide
Range on Protein: 154-204
Range on HMM: 1-84/425
Sequence Identity: 19% (16 aa)

KLGEGVFGEVFSCYTPEGDG-------------LAVKIMPIEGKEL-----------INDEKQK---------TFEEILPEMVI
.||.| ||.|. |.  .  |              |.||.. .               |...|.|         . .... |. |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEI

Kinase AqueK156.AA STE20 150-199 29 1.5e-05 16.62 In-house 2-56 (288) Show / Hide
Range on Protein: 150-199
Range on HMM: 2-56/288
Sequence Identity: 29% (17 aa)

RTLQKLGEGVFGEVFSCYT-PEGDG----LAVKIMPIEGK---ELINDEKQKTFEEIL
  |.|.|.| .|.|. .|  | |.      |.|.|..| .       ||..  . ||.
ELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ---DEWEDIQKEIS

Kinase AqueK156.AA S_TKc 149-434 12 8.2e-05 -106.36 SMART 1-231 (231) Show / Hide
Range on Protein: 149-434
Range on HMM: 1-231/231
Sequence Identity: 12% (41 aa)

KRTLQKLGEGVFGEVFSCYTPE-GDGLAVKIMPIEGKELINDEKQKTFEEILPEMVISKLGIGKGKYPEFLINAWDNWDEKEESDNDRPDVFSPKQLYVM
 . |.|.|.| ||.|. |.  . |   |.||..               | |. |. | |         .....  | ...              . ||. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK------HHPNIVKLYDVFQD--------------DHLYMV

FAFENS--GCALEAFTFH---------SKREAMSVLAQIAATLAVGEAALKFEHRDMHRGNILVRRTKEEKMVFVID---SHKYVLPSEGVHVTVIDYTL
. . .   |  ..    .         .  .| ....||.  |.      .. |||    |||. .      . ..|   . ..         | .  |.
MEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTP

S-----RLSQGSCTSYND----------------LNNLPWLFKGHGGIQHDTYLRMRNATKSDWSKFAPRTNACWLYYIVNKMAIKSRVKYVTRAQIQAA
       |      .|.                     |.        .. .. ...                                           
WYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----------------------------------------SPE

FEPLVNQFLNYD-----SAKDIFL--------EYF
.  .... |..|     .| ...         ..|
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK156.AA CDK-Unclassified 150-164 53 0.000103 11.28 In-house 2-16 (324) Show / Hide
Range on Protein: 150-164
Range on HMM: 2-16/324
Sequence Identity: 53% (8 aa)

RTLQKLGEGVFGEVF
|...|.|||.||.|.
RMQCKYGEGTFGCVC

Kinase AqueK156.AA Ciliate-C1 150-178 30 0.000252 6.52 In-house 2-31 (328) Show / Hide
Range on Protein: 150-178
Range on HMM: 2-31/328
Sequence Identity: 30% (9 aa)

RTLQKLGEGVFGEVFSCYTPEGD-GLAVKI
. . ..| |   .|| |. | ..  .|||.
KIMKTIGHGYTCKVFYCKMPNNQKVYAVKQ

Kinase AqueK156.AA CMGC 149-167 36 0.000923 7.21 In-house 1-19 (513) Show / Hide
Range on Protein: 149-167
Range on HMM: 1-19/513
Sequence Identity: 36% (7 aa)

KRTLQKLGEGVFGEVFSCY
   ..|.||| .|.|..|.
YEIIKKIGEGTYGVVYKCR