Gene AqueK125 (A.queenslandica)

AqueK125

Species: A.queenslandica
Alias: AqueK125
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
AqueK125.AA Protein None 409 None Fasta, JSON
AqueK125.kin_dom Protein Kinase Domain None 86 None Fasta, JSON

Protein domain

Protein domains of AqueK125.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK125.AA ERK7 92-224 47 1e-58 199.3 In-house 141-263 (292) Show / Hide 
Range on Protein: 92-224
Range on HMM: 141-263/292
Sequence Identity: 47% (63 aa)

LADFGLAHSLASTSNEGSKGVGGDGVNDFNPAMTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTLPPPSRQD
..||||| |.|.. .           .. ||..|.||||||||.|||||||.|||.||||||.||||.||.  .|..||.||.||...|. |.| |...|
VCDFGLARSIAQQEEY----------DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQED

VESIKSPYAKAILDQIIHKRHKYLTDILPQADP
.|.|.| ||  .|.|......| | ...||. .
IEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCD
Kinase AqueK125.AA MAPK 92-224 36 1.3e-46 159.17 In-house 158-299 (328) Show / Hide 
Range on Protein: 92-224
Range on HMM: 158-299/328
Sequence Identity: 36% (53 aa)

LADFGLAHSLASTSNEGSKGVGGDGVNDFNP--AMTDYVATRWYRSPEILLG--SRRYTRGVDMWSLGCILAEMIA-SRPLYPGSSTINQLNRIMSTLPP
..||||| |.......  . . .  .  |     ||.||||||||.|||.|.  ...|| .|||||.|||.|||.   .|| ||...|.|.|.||..|. 
ICDFGLARSIDPEYHHHHQQDDP--HC-F-QKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGT

PSRQDVESIK-SPYAKAILDQI---IHKRHKYLTDILPQ----ADP
||..... |. |. |.  . .     ..  | .....|     |.|
PSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP
Kinase AqueK125.AA CMGC 92-199 29 4.6e-39 125.38 In-house 245-401 (513) Show / Hide 
Range on Protein: 92-199
Range on HMM: 245-401/513
Sequence Identity: 29% (48 aa)

LADFGLAHSLASTSNEGSKGVGGDGVNDF---------NPAMTDYVATRWYRSPEILLGSRRYT---------RGVDMWSLGCILAEMIAS--------R
..||||| .. . |..  . ..      |         | ..|.||.|||||.||||||...||          ..||||.|||.|||.          .
ICDFGLARWYHPHSDHHFQQQPQS----FKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGK

PLYP-----------GSSTINQLNRIMSTLPPP----------------SRQDVESIKSPY
|| |           |.|.|.||..|. .| .|                .... . || |.
PLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPW
Kinase AqueK125.AA p38 124-227 41 1.2e-35 119.08 In-house 160-263 (289) Show / Hide 
Range on Protein: 124-227
Range on HMM: 160-263/289
Sequence Identity: 41% (43 aa)

MTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQAD
||.||||||||.|||.|   .||  ||.||.|||.||.|  |.|.||.  |.||.|||. .  |..  .. |.|  |.. .  .     . .......|.
MTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGAN

PSKI
|. |
PQAI
Kinase AqueK125.AA CDK 92-184 39 4e-35 109.71 In-house 154-241 (284) Show / Hide 
Range on Protein: 92-184
Range on HMM: 154-241/284
Sequence Identity: 39% (39 aa)

LADFGLAHSLASTSNEGSKGVGGDGVNDFNPAMTDYVATRWYRSPEILLGSRRYT--RGVDMWSLGCILAEMIA---SRPLYPGSSTINQLNRIMSTL
.||||||    . ..         .  . | ..|  | |.|||.||.||||..|.   ..||||.|||.|||.     .|| ||.| |.|| .|  ..
IADFGLARAFGIPHQ---------MS-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRIC
Kinase AqueK125.AA ERK 93-201 40 6.7e-33 115.63 In-house 150-251 (307) Show / Hide 
Range on Protein: 93-201
Range on HMM: 150-251/307
Sequence Identity: 40% (45 aa)

ADFGLAHSLASTSNEGSKGVGGDGVNDFNPAMTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTLPPP-SRQD
.|||||  ......|...          .. ||.||||||||.|||.|  . ||. .|.|| |||.|||.. .|| || ....|.||| ...  | | .|
CDFGLARCFDASYQENHE--------CNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEED

VESIKSPYAK
.. |.|. |.
LQYICSENAW
Kinase AqueK125.AA ERK1 124-224 45 6.5e-32 112.34 In-house 160-260 (289) Show / Hide 
Range on Protein: 124-224
Range on HMM: 160-260/289
Sequence Identity: 45% (46 aa)

MTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQAD
.|.|||||||| |||.| |. ||. .|.|| |||||||.. ||..||   . ||| |.. |  ||..|.. |    |.. |  . || .  .  . |.||
LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKAD

P
.
S
Kinase AqueK125.AA CDC2 128-180 57 2.6e-31 93.07 In-house 166-221 (301) Show / Hide 
Range on Protein: 128-180
Range on HMM: 166-221/301
Sequence Identity: 57% (32 aa)

VATRWYRSPEILLGSRRYTRGVDMWSLGCILAEM---IASRPLYPGSSTINQLNRI
| |.|||.||||||..||. .|||||.|||.|||   .  .|| .| | | || .|
VVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKI
Kinase AqueK125.AA CDKL 125-184 56 1e-28 95.28 In-house 157-216 (286) Show / Hide 
Range on Protein: 125-184
Range on HMM: 157-216/286
Sequence Identity: 56% (34 aa)

TDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTL
||||||||||.|| |.| . |   ||.|..||..||||   ||.||.| | || .|. .|
TDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLWPGQSDIDQLYHIQKCL
Kinase AqueK125.AA ERK5 124-224 38 1.4e-27 97.98 In-house 165-266 (295) Show / Hide 
Range on Protein: 124-224
Range on HMM: 165-266/295
Sequence Identity: 38% (39 aa)

MTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQ-IIHKRHKYLTDILPQA
||.|||||||| ||... |  ||  .|.|| |||. |||| | ..||   |.||. ||  |  |. . .... .   .. . . .  .. | .  . |.|
MTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKA

DP
|.
DR
Kinase AqueK125.AA Pkinase 92-210 26 3.8e-27 97.08 Pfam 153-276 (293) Show / Hide 
Range on Protein: 92-210
Range on HMM: 153-276/293
Sequence Identity: 26% (38 aa)

LADFGLAHSLASTSNEGSKGVGGDGVNDFNPAMTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIASRPLYPGS----STINQLNRIMSTLPPP
..|||||  .                .  |. ||... |.||..||...|.. |.. |||||.||||.||.  ||..||.    . ..|. .|  ...||
ICDFGLAKQFD---------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP

SRQDVESIKS-------------------PYAKAILDQIIHK
 . | .   |                   . .| ... ...|
LHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK
S_TKc AqueK125.AA S_TKc 12-215 16 2.9e-08 -55.64 SMART 17-231 (231) Show / Hide 
Range on Protein: 12-215
Range on HMM: 17-231/231
Sequence Identity: 16% (44 aa)

SCSTKHCPCFLAVRKYDPDLCSTCGAGDNLEMKFTM------CKNVSIQRGQKKHLLMAPSDVAG-----WGIFLKDGA------EKNEFISEYCGE---
 |  |.     |. . .             |..  .      .|   . .   .|| |    . |       .  | |            .  |. .   
KCRHKKTGRIVAIKIIK--------EHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICC

---------------------------LADFGLAHSLASTSNEGSKGVGGDGVNDFNPAMTDYVATRWYRSPEILLGSRRYTR-GVDMWSLGCILAEMIA
                           ..|||||  |                       | .. |.||..||.|     |..  .|.||.||||.||..
ALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-----------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

SRPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQIIHK-----------R-------HKYL
 .|..|       ...|.               || || ..... .|           .       | ..
GYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
SET AqueK125.AA SET 70-123 30 0.000869 17.3 Pfam 1-42 (81) Show / Hide 
Range on Protein: 70-123
Range on HMM: 1-42/81
Sequence Identity: 30% (17 aa)

GWGIFLKDGAEKNEFIS--EYCGELADFGLAHSLASTSNEGSKGVGGDGVNDFNPA
|||.| .   .|.|||   |||||. .   | .             .|.   .|.|
GWGVFATRDIPKGEFICFSEYCGEIIT-DEA-RR----------Y-IDAT-MGNWA
SET AqueK125.AA SET 294-409 33 9.4e-31 109.4 SMART 1-108 (114) Show / Hide 
Range on Protein: 294-409
Range on HMM: 1-108/114
Sequence Identity: 33% (43 aa)

KHLLMVLSDVAGWGIFLKDGAEKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDYVVDATR----KGNKIRFANHSVDPNCYAKVMIVGG---
|.. .  .. .|||.| ..  .|.||| ||.||||                 ...|.     ..||.|    |||..|| ||| .||||.....|.|   
KKVEVFKTPWKGWGVFATEDIPKGEFICEYVGEII-----------------FYMFD-----CIDARRMNHGKGNWARFINHSCEPNCYVQFWFVNGFDP

-------DHRIGIFAKHNIELEEELFFDYR
       ...|.|||...|.  ||..||| 
RGNSMHWHPHIVIFAMRDIKPGEEITFDYG
SET AqueK125.AA SET 305-409 39 3.9e-27 101.26 Pfam 1-81 (81) Show / Hide 
Range on Protein: 305-409
Range on HMM: 1-81/81
Sequence Identity: 39% (42 aa)

GWGIFLKDGAEKNEFIS--EYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDYVVDATRKGNKIRFANHSVDPNCYAKVMIVGGDHRIGIFAKHNIELEE
|||.| .   .|.|||   |||||||. ||| ||                  | .||| .||  || ||| .|||.....    ...|..||. .|.  |
GWGVFATRDIPKGEFICFSEYCGEIIT-DEA-RR------------------Y-IDAT-MGNWARFINHSCPPNCEFQWW----EPHIVFFAIRDIKPGE

ELFFDYR
|...|| 
EITYDYG