Gene AqueK104 (A.queenslandica)

AqueK104

Species: A.queenslandica
Alias: AqueK104
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: PFTAIRE

Sequence

Name Sequence Type Origin Length Description Download
AqueK104.AA Protein None 546 None Fasta, JSON
AqueK104.kin_dom Protein Kinase Domain None 290 None Fasta, JSON

Protein domain

Protein domains of AqueK104.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK104.AA PFTAIRE 231-520 64 4.6e-190 637.7 In-house 1-287 (287) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-287/287
Sequence Identity: 64% (189 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDTDLSRYMEKHPGPLD
|.||| ||||||||||||||. |.  ||||||||. |||||||||||     |||||.|||||||.|||||||   ||||||||.|||. ||.|||| ..
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQEEGTPFTAIRE-----ASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMH

PRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCIFVEMLTGK
|.||.  | |||||| .||.|..||||||||| |. | |||||||||||||||||..|||||||||||||||||.|||.| |.|||||||||||||..|.
PNNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQ

PLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYE--QCPPLGLEVVAPILHPKTKVGDLAMKLLQLIPSNRITADDALAHEYF
|.|||.| ..|||..|. .||||.  |||||. ||.|.|.. .     |  |. . | .    .  ||.||.||. | .|. |..|. |.||
PAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase AqueK104.AA PCTAIRE 231-520 61 5.5e-167 561.05 In-house 1-291 (291) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-291/291
Sequence Identity: 61% (182 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDTDLSRYMEKHPGPLD
|.||. ||||.||||||. |   .  ||||||||  ||| |.|||||     .||||.||||||| |||||||   ||.|||| | ||..||.     ..
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHEEGAPCTAIRE-----VSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMN

PRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCIFVEMLTGK
  |||..| |||||| .||||||||||||||| |.|  |||||||||||||||||||||||||||||||||||||||||| |..||||||||| || ||.
MHNVKLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGR

PLFPGLK-----GVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILH-PKTKVGDLAMKLLQLIPSNRITADDALAHEYF
||||| .     || |||  | .||||| . |||||. ..|.|.... . ... |  .|| |    ..  ||  .|||. . ||. |..|. | ||
PLFPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase AqueK104.AA CDK 231-520 45 1.7e-160 517.33 In-house 1-284 (284) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-284/284
Sequence Identity: 45% (150 aa)

YKKLEALGEGSYATVYKGISIANG-----HYVALKEIRLNS-----E-EGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTS-----------NNLT
|.||| .|||.|..|||...  .|     ..||||.||. .     | || |.|||||      |||| | |.||| |||..||.           |.|.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIRE-----ISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLY

FVFEYVDTDLSRYMEKHPGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGE-----LKLADFGLARAKSV------PTKTYSHEVVTLW
.||||.|.||. ||.          .| .. ||||||..||...|.||||||||||.|.|||     ||.||||||||...      |..||.|||||||
MVFEYMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLW

YRPPDVLMGSTDYF--TSLDMWGVGCIFVEMLT---GKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILHPKTK
||.|..|.||..|   |. |||.|||||.||.|   .|||||| .   ||| .|  |.|||.  .|||||.||.|                         
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPG-DSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------

VGDLAMKLLQLIPSNRITADDALAHEYF
  || .|.|.. |..||.|..|| |.||
--DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK104.AA CDK5 231-520 54 6.5e-156 496.48 In-house 1-287 (287) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-287/287
Sequence Identity: 54% (161 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSE-EGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDTDLSRYMEKHPGPL
|.|.| .||| |.||||.     . .||||..||.|| ||.| |||||      .||| ||| ||| |||.||. . || |||..| || .||..  | .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIRE-----ICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEM

DPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCIFVEML-T
|.. .| .. |||.|| ||| ...||||||||| | | ||||||||||||||  .| ..|||||||||||||||||||  | || ||| .|||| ||  .
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

GKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYR--PEQYEQCPPLG-LEVVAPILHPKTKVGDLAMKLLQLIPSNRITADDALAHEYF
|.|||||  .| ||| ||  |.|||.  .||..|.||.|.   .||.  |.   .. . | |  |    ||  |.||. |  ||.|..|| | ||
GRPLFPG-NDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGM--DLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK104.AA CDC2 231-520 48 3.1e-138 427.7 In-house 1-301 (301) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-301/301
Sequence Identity: 48% (149 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGT---PFTAIREGIMTFASLLKGLK-HANIVILHDIIHTSNNLTFVFEYVDTDLSRYME-KH
|.|.| .|||.|  |||..    . .|||| ||| .|.     | |||||      |.|| || | ||| |||.||  |.|  ||||.| || .||. . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIRE-----ISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSI

PG--PLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYS--HEVVTLWYRPPDVLMGSTDYFTSLDMWGVGC
|   ...| .|| ...|.|.|..|||.|.|.||||||||||.. .|..|.|||||||| ..| .||   |||||||||.| .|.|. .| |. ||| .||
PKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

IFVEM---LTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPI-------LHPKTKVGDLAMKLLQLIPSNRITA
|| ||    | ||||.| .   ||| .|  ||||||. ||||||.||.| .  . . .| .|. . |        .  . .  || |..||. |..||.|
IFAEMFMDVTKKPLFHG-DSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKN-TFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISA

DDALAHEYF
..||.| ||
KEALQHPYF
Kinase AqueK104.AA CMGC 231-520 25 8.99999999999e-123 405.55 In-house 1-513 (513) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-513/513
Sequence Identity: 25% (132 aa)

YKKLEALGEGSYATVYKGIS--------------IANGHYVALKEIRLN----------SEEGTPFTAIREGIMTFASLLKGLK----------------
|.... .|||.|..|||..               . .. .||.| |...           ..| |..|.||      ..|| |.                
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALRE-----IKILKHLNKNHDPNWQRRDDPDNK

-HANIVILHDIIHTSN-----------------NLTFVFEYVDTDLSRYMEKHPG--------PLDPRN------------VKILL------IQLLRGLN
 | ||| |.||....|                 .| .||||.|.|| .|......        ||..              .| ..       |.||||.
HHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLK

--FCHRRK--ILHRDLKPQNILLNHNGEL--------------------KLADFGLARAKSVP---------------------TKTYSHEVVTLWYRPP
  .||...  |.||||||.|||.|||.||                    |..||||||. ...                     ...|.|.|||.|||.|
LKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAP

DVLMGSTDYF---------TSLDMWGVGCIFVEMLTG--------KPLFPGLKGV----------YDQLNRIWSILGTPN---------------NTTWP
 .|.|...|          |. |||.||||| ||.||        ||||||  ..          .|||..|  .||||.                 .||
EILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWP

GVTDLPEY---------------RPEQ----------YEQCPPLGLEVVAPILH---------------------------------PKTKVGDLAMKLL
....||.|                .|           . ..||  .. . | ..                                    .  || .|.|
NMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKML

QLIPSNRITADDALAHEYF
|. |..||||..||.|.||
QYDPDKRITAEQALQHPYF
Kinase AqueK104.AA CDK7 231-467 42 2.7e-104 278.65 In-house 1-236 (288) Show / Hide 
Range on Protein: 231-467
Range on HMM: 1-236/288
Sequence Identity: 42% (102 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIR-----LNSEEGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDTDLSRYMEKH
|.|.. .||| .|||||.   . |  || |.|.        . |  .|||||       .|. ..| |.. | ||.    |.  ||.. |.||    .  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIRE-----IKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDK

PGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCIFVE
   | | ..|   ...|.|| .|||  |||||||| | |.| ||.||.|||||||.   | . |.| ||| ||| |  | |   | |. ||| ||||| |
SIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAE

MLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEY
 .   | .||   . ||| || ..||||.  .||... ...|
LMLRVPYLPGDSDI-DQLTRIFQTLGTPTEEEWPNMCCMMDY
Kinase AqueK104.AA PITSLRE 231-520 40 4e-86 292.42 In-house 1-295 (295) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-295/295
Sequence Identity: 40% (121 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLN---SEEGTPFTAIREGIMTFASLLKGLKHANIVILHDII--HTSNNLTFVFEYVDTDLSRYMEKH
...|   .|| |  ||..     .  |||| . .      || | |..||    .  .|..|.| ||| .  |.   . .    |.|||. ||   ||..
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLRE----INMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENM

P---GPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCI
     |  |  .| |..|||||  . |  .|.|||||  |.|..|.| ||..||||||    | | |.  ||||||| | .| |.  | | .||| ||||
KRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCI

FVEMLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQ-YEQCPPLGLEVVAPILHPKTKVG-DLAMKLLQLIPSNRITADDALAHEYF
| |..|.||||.| |.  ||.|.|   .|||.   |||.|.||  .  .  .. |.  |    |     . .| ||  ..| . | |||||.||| |..|
FAEFITMKPLFQG-KSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase AqueK104.AA S_TKc 231-520 28 3e-82 280.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDT---DLSRYMEKHPG
|..|. .|.|....|||.. .  |..||.|.|.             | |.   ..||  .| ||| |.|.... ..| .|.||.|.   || .|..|...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

P-----LDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFT-SLDMWGVGC
.     ...  .. .. |....|..||...|.||||||.||||..  ..|..||||||         .. ..|.||..| ||     | . . |.| .||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

IFVEMLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILHPKTKVGDLAMKLLQLIPSNRITADDALA-----
|. |||.|.|.||       |..... ..|                                         . |. .|.||  |..|.|| .||.     
ILYEMLCGYPPFP-------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HEYF
  |..|
KCHPWF
Kinase AqueK104.AA Pkinase 231-520 31 3.7e-78 270.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPF-TAIR--EGIMTFASLLKGLKHANIVILHDIIHTSNNLTFVFEYVDT-----DLSRYM
|.... .|.||...|||.. . .|. ||.|.|.. .|.     |..|  |     ....| |.| ||| |.|. ...... .|.||..      ||..|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSE-----IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

E-KHPGPL--DPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGEL----KLADFGLARAK-SVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSL
. .  |..  ... .|  . |.||||..||...|.||||||.|||...||..    |..|||||. .   .   ... ..|.||..| |..|...| .. 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWGVGCIFVEMLTGKPLFPGL---KGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILHPKTKVGDLAMKLLQLIPSNRITA
|||..|||. |||.|.|.|||    .. .||. .|  |.|.|.   ||   . . .   .. . .   .... . ...  |  |.  ..|.. |. |.||
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECK--DFIKWCLCKDPKKRPTA

DDALAHEYF
...| |..|
EQILQHPWF
Kinase AqueK104.AA CDK4 231-520 40 3.3e-77 262.83 In-house 1-290 (290) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-290/290
Sequence Identity: 40% (122 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRL-NSEE--GTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNN------LTFVFEYVDTDLSRY
|... ..||| | |||.  .. .|| |||| .|  ..||  | |   |||   .    |. . |.||| | |. |..        .| ||| .| ||. |
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIRE--ISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTY

MEKHPGP-LDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVG
..| | | . |  .| .  |||||. | |   | ||||||||||.. .|..|||||||||  |  ..  .  ||||||| | ||  |. | |  ||| ||
LDKCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPV-VVTLWYRAPEVLLQSY-YNTPVDMWSVG

CIFVEMLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILHPKTKVGDLAMKLLQLIPSNRITADDALAHEYF
||| ||   .|||.|   . ||| .|  . |.|    ||    ||    . . |  |  .. . | .    .  ||  | |   .. |..|  .| | ||
CIFAEMYCRRPLFCGQSEK-DQLHKIFDVMGLPPEDDWPRDVSLPW---DHFPQRHPRPFKDFCPHMCKQGD--DLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase AqueK104.AA CRK7 231-465 35 1.4e-72 247.39 In-house 1-284 (343) Show / Hide 
Range on Protein: 231-465
Range on HMM: 1-284/343
Sequence Identity: 35% (102 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSE----EGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHT------SNNLT----FVFEYVDT
|....  ||| |  |||     .| .|||| .|.  |    || | ||||| |     .|. |.|.||| |..|.        ...       ||||.| 
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIRE-IK----ILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDH

DLSRYMEKH-PGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVPT--KTYSHEVVTLWYRPPDVLMGSTDY---
||.  .|        . ..| .. ||| |.. ||....||||.|  |||.| .||.|.|||||||        . |   |.|||||||  | | . |   
DLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQ

-----------------------------------FTSLDMWGVGCIFVEMLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLP
                                    .. |||..|||..| .|.||.|.|     .||  |  | |.||   || |..||
HILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEM-AQLEKIYKICGSPNPNNWPEVMKLP
Kinase AqueK104.AA Pkinase_Tyr 231-381 30 5.7e-12 41.17 Pfam 1-160 (270) Show / Hide 
Range on Protein: 231-381
Range on HMM: 1-160/270
Sequence Identity: 30% (50 aa)

YKKLEALGEGSYATVYKGISI----ANGHYVALKEIRLNSEEGTPFTA-IREGIMTFASLLKGL-KHANIVILHDIIH-TSNN--LTFVFEYVDT-DLSR
 .... ||||.. .||||.       ..  || | ..    ||.   . .||  |  |...| | .| ||| |. ..   .    .  |.||.   ||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YMEKH---PGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARA
|  ||   ..||..       .|  .|... ..... ||||   |.|...|.  | .||||||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase AqueK104.AA TyrKc 231-520 20 9.6e-12 -32.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 231-520
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGL--KHANIVILHDIIHTS-------NNLTFVFEYVDT-DLSR
 .... |||| . .||||. .     || | .. ..         || .|  |.... |  .| ||| |. .. ..         |  |.||..  ||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YMEKHPGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNHNGELKLADFGLARAKSVP------TKTYS-----HEV--VTLWYRPPDVLMGS
|  || . | ..      .|  .| .. |.... ||||   |.|...|.  | .||||.|.          ...|.     ..   . .   .| ..   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--N

TDYFTSL-DMWGVGCIFVEMLT-GKPLFPGL----KGVYDQLNRIWSI--LGTPNN----TTWPGVTDLPEYRPEQYEQCPPLGLEVVAPILHPKTKVGD
.  ||.  | |  |    |..| |..  ||     .  .. .... .   .  | |                                    .  ... .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------FVCCPDEMYQ

LAMKLLQLIPSNRITADDALAHEYF
.  .  .  |..| |  .   ||.|
IMKQCWHEDPEDRPTFSEI--HECF
Kinase AqueK104.AA CDK7 495-520 30 3.5e-09 20.15 In-house 263-288 (288) Show / Hide 
Range on Protein: 495-520
Range on HMM: 263-288/288
Sequence Identity: 30% (8 aa)

DLAMKLLQLIPSNRITADDALAHEYF
||  ... . |..|.|. ..| ..||
DLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK104.AA CRK7 495-520 46 9.3e-08 22.62 In-house 318-343 (343) Show / Hide 
Range on Protein: 495-520
Range on HMM: 318-343/343
Sequence Identity: 46% (12 aa)

DLAMKLLQLIPSNRITADDALAHEYF
||. |.| | |. |.|| ..| |..|
DLLDKMLCLDPKKRFTAEECLQHDWF