AqueK101

Species: A.queenslandica
Alias: AqueK101
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK9

Sequence

Name Sequence Type Origin Length Description Download
AqueK101.AA Protein None 366 None Fasta, JSON
AqueK101.kin_dom Protein Kinase Domain None 294 None Fasta, JSON

Protein domain

Protein domains of AqueK101.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK101.AA CDK9 19-312 57 1.6e-202 679.13 In-house 1-340 (340) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-340/340
Sequence Identity: 57% (197 aa)

YEKLTKVGQGTFG-----------EVFKAKDRKTGRLVALKKVCMENEKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKG--SIYLVLDF
|||| |.||||||           |||||. .|..|.||.||| ||||||||| ||||||..||||.| |.|||.|||| |||.||| |.  ..|||.||
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

CEHDLAGLLECKEIKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARAL---NKGANQR--YTNRVVTLWYRPPELFLGE
|||||||||   ..||||..|| .||.| | | ||| | |||||||  |.|.|. | |||||||||||      .|  |  ||||||||||||||| ||.
CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD

RNYGPPIDMWGAGCIMAEMWTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKL------ELPQKENRKLKERLRHFVE-------------
|||||||||||||||||||||| |||||.|||.| .|| |||||| |  | ..|..| ..|.      |||.   ||.|.|.. ..              
RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK

---------DPYALDLIDKLLMLDPRKRIDADSTLEHDFF
         |..|..|||||| .|| ||.|.|  |.||.|
NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF

Kinase AqueK101.AA CDK 19-312 41 1.3e-151 488.44 In-house 1-284 (284) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-284/284
Sequence Identity: 41% (135 aa)

YEKLTKVGQGTFGEVFKAKDRKTG-----RLVALKKVCMEN-----EKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKG----SIYLVLD
|||| |.|.||.|.|.||.|..||     ..|||||. |||     ||||||.||.||| .|. | | |||.| ..| .|....|. |.    ..|.| .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

FCEHDLAGLLECKEIKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGE-----LKLADFGLARALNK-----GANQRYTNRVVTLWYRPP
...|||.....          ||..|.|| ..|.|.| |.|.|||.|  |||....||     ||.|||||||| .      . |. ||..|||||||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELFLGERNYG--PPIDMWGAGCIMAEMWT---RRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKLELPQKENRKLKERLRHFVEDPYALDLI
|| ||...|.  .|||||..|||.|||.|   |.|...||.|. |. .|...||. ..  | ||.|| .|                           ||.
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------DLL

DKLLMLDPRKRIDADSTLEHDFF
.|.|..|| ||| |.  |.|..|
NKMLCYDPKKRISAEQALQHPYF

Kinase AqueK101.AA CRK7 19-312 44 1.4e-135 456.7 In-house 1-343 (343) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-343/343
Sequence Identity: 44% (151 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENE---KEGFPMTALREIRILQLLQHNNIVNLVEICRSK--ATPYNRDKGSIYLVLDFCEHDLAGL
||..  .| ||.| | |||. .|| .|||||| |.||   ||||| || |||.||. |.| ||||| ||  .|  |   ...|||.|.| .   |||.||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LECKEIK-FSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGA-NQRYTNRVVTLWYRPPELFLGERNY--------
|| ||.. ||....| .| ||   ..|.| .|.|||| |  |||.  .||.|.||||||| .|.    . |||||.||||||||| ||| .|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GPPIDMWGAGCIMAEMWTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKLELPQKENRKLK
                              || ||||. |||..|  |..|| ||  | .|. .| ..|||  |  |  | || ... .   .. ||.| 
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

ERLRH----FVEDPYALDLIDKLLMLDPRKRIDADSTLEHDFF
|   |       .. .||| ||.| ||| ||. |  .|.||.|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF

Kinase AqueK101.AA CMGC 19-312 24 1.2e-129 428.54 In-house 1-513 (513) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-513/513
Sequence Identity: 24% (124 aa)

YEKLTKVGQGTFGEVFKAKD--------------RKTGRLVALKKVC---MEN------EKEGFPMTALREIRILQLLQ-----------------HNNI
||.. |.|.||.|.|.|..|              ..|...||.||.    .|.      ||.|||..|||||.||. |.                 ||||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNLVEICRSKATPYNRDK---------GSIYLVLDFCEHDLAGLLECKE--------IKFSLSE------------IKNIM------QQLFNALA--YIH
|.| .|...| .  | ..          ..||| ....|||..... .         ...|  .            ||..|      .|....|.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

GNN--ILHRDMKSCNILVTRKGEL--------------------KLADFGLARALNKGANQR--------------------YTNRVVTLWYRPPELFLG
 ..  |.|||.|  |||.. ..||                    |..||||||....  ...                    ||..|||.|||.||. ||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

E---------RNYGPPIDMWGAGCIMAEMWTR--------RPIMQGDTE-----------QKQITLICQLCGSIS---------------PTEWAGVEKL
          ..|..|||||..|||.|||.|.        .|. .|..|           . |. .|....|...               . || .. ||
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

EYYQK-------------------------LELPQKENRKLKERLRHFV---------------------------------EDPYALDLIDKLLMLDPR
 .|.|                         . .|..  ...|.    .                                  .|| |.||..|.| .|| 
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRIDADSTLEHDFF
||| |.  |.|..|
KRITAEQALQHPYF

Kinase AqueK101.AA CDC2 19-312 36 5.4e-111 342.44 In-house 1-301 (301) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-301/301
Sequence Identity: 36% (113 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEG--FPMTALREIRILQLLQ-HNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEHDLAGLLE
|.|. |.| ||.|.|.|.||..|...|||||.  |.| ||  .| ||.||| .|. |. | ||| | ..  .          ..|.| .....||  ...
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---------NKLYMVFEYLDMDLKKYMD

-CKEI--KFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGANQRYT--NRVVTLWYRPPELFLGERNYGPPIDMW
  .    ..... .|..| |. ..... | . |.||| |  |||. .||..|.|||||||| .   .. ||    |||||||.||. ||.. |  |.|||
MSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRT-YTTEHEVVTLWYRAPEILLGCKRYSTPVDMW

GAGCIMAEM---WTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKL--ELPQKENRKLKER----LRHFVEDPYALDLIDKLLMLDPRKRI
  |||.|||    |..|. .|| |  |.  | .  |. .  .| ||..| .|.    .....  .|. ..    .  .  || ..||....| .|| |||
SIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRI

DADSTLEHDFF
 |.. |.| .|
SAKEALQHPYF

Kinase AqueK101.AA PITSLRE 19-312 41 1e-107 364.13 In-house 1-295 (295) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-295/295
Sequence Identity: 41% (127 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCME--NEKEGFPMTALREIR-ILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEHDLAGLLE
...| ... ||.|.|..|||..|.. ||||.. ||   |||||| |.||||  ||  ||| ||||. ||   .      .. .||.|... ||||..|.|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGS------NMDKIYMVMEYVEHDLKSLME

CKE---IKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGAN-QRYTNRVVTLWYRPPELFLGERNYGPPIDMWG
       .|...|||  |||| .. .. | | |.||| |  |.| . || ||..||||||    | .   ||  ||||||| ||| || . | .|.||| 
NMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREY--GSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWS

AGCIMAEMWTRRPIMQGDTEQKQITLICQLCGSISPTE--WAGVEKLEYYQKLE-LPQKENRKLKERLR--HFVEDPYALDLIDKLLMLDPRKRIDADST
 |||.||. | .|..||. |  ||  | .. |   |||  | |. .|    ... .|.     |..|      . |  ..||  ..| ..| .|| |.  
VGCIFAEFITMKPLFQGKSEIDQINCIFKEMG--TPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISD-TGFDLLNQMLTYNPKNRITASDA

LEHDFF
| |..|
LKHPWF

Kinase AqueK101.AA CDK7 19-312 38 8.8e-107 285.43 In-house 1-288 (288) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-288/288
Sequence Identity: 38% (115 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVC----MENEKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEHDLAGLL
|||. ..| |.|. |.|| | .||. || ||.      .  | |  .||.||| ||| .|| |...|. |   |         .|.||.|| . ||    
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS--------NIQLVFDFMDWDLEVVI

ECKEIKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGA-NQRYTNRVVTLWYRPPELFLGERNYGPPIDMWGAG
. |.| .  ..||..| ..   | | | | |||||.|  | |.   |.||.|||||||.   |. |. ||  ||| ||| |||  | | ||. .|||  |
KDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFY--GSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVG

CIMAEMWTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKL-ELPQKENRKLKERLRHFVEDPYALDLIDKLLMLDPRKRIDADSTLEHDFF
||.||   | |.. || .  |.| |.|  |  .. || .. ..  | |. . |      |...     .|  .|||. ... ..| ||. .   |....|
CIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDD--LLDLMCGMWTMNPCKRWTCTQCLKMPYF





Kinase AqueK101.AA CDK5 19-312 37 2.1e-94 298.67 In-house 1-287 (287) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-287/287
Sequence Identity: 37% (113 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEHDLAGLLECKE
|||. |.| ||.| |.||....|. .||||.| ...| || | ||.||| .|. |.|.||| |  .  |           . ||  ||  ||   ..  .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKK--------LTLVFEFCDQDLKKYMDSCN

IKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGANQRYTNRVVTLWYRPPELFLGERNYGPPIDMWGAGCIMAE
 . ..  || .| ||   ||. | ...||||.|  | |. ..|||||||||||||     .  |.  |||||||||   .| . |  .|||| .|||.||
GEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC-YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAE

MW-TRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQ--KLELPQKENRK-LKERLRHFVEDPYALDLIDKLLMLDPRKRIDADSTLEHDFF
|  . ||   |  .. |  .| .. |. .  .| .. ||  |.    ..|  . .. ...  ..   |   .||  |.|...| .||.|.  |.| .|
MANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK--LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase AqueK101.AA S_TKc 19-312 28 1.8e-92 314.42 SMART 1-231 (231) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEH---DLAGLLE
||.| |.|.|.||.|.|....||||.||.|..           ...|||.||.  .| |||.| .....         ...|.|...|..   ||  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIK

CKEIK-----FSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGANQRYTNRVVTLWYRPPELFLGERNYGP-PIDM
 .  .     |.  ... .|.|...||.|.| ..|.||| |  |||...  ..|..|||||| |        |  ..|.||..||..     ||. ..|.
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDW

WGAGCIMAEMWTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKLELPQKENRKLKERLRHFVEDPYALDLIDKLLMLDPRKRIDADSTLE-
|  |||..|| ...|  .      |. .. ...|                                      .| |.|.|.|.|  ||.||. |   |. 
WSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HDFF
      | .|
EWDIKCHPWF

Kinase AqueK101.AA Pkinase 19-312 31 1.8e-91 314.96 Pfam 1-293 (293) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEGFPMTALR--EIRILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEH-----DLA
|... |.|.|.||.|.|.....||..||.|... ..||.....|..|  ||.|.. |.| ||| | .....        |..||.|...||.     ||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVMDLF

GLLE-CKEIKF--SLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGEL----KLADFGLARALNKGANQRYTNRVVTLWYRPPELFLGERNYG
 ...  .. .|  |  |.|..| |.. .|.|.| ..|.|||.|. |||. ..|..    |..|||||. ..   |. .| ...|.||..||. .| . ||
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

PPIDMWGAGCIMAEMWTRRPIMQGD----TEQKQITLICQLCGSISPTEWAGVEKLEYYQKLELPQKENRKLKERLRHFVEDPYALDLIDKLLMLDPRKR
|..|||..|||..|| ..||. .|.    .   |. .||.  | . . .|       |.  .   . .     ....    .. ..|.|...| .|| ||
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKR

IDADSTLEHDFF
. |.  |.|..|
PTAEQILQHPWF

Kinase AqueK101.AA CDK10 19-312 40 1.4e-88 300.55 In-house 1-285 (285) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-285/285
Sequence Identity: 40% (118 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEGFPMTALREIRILQLLQHNNIVNLVEICRSKATPYNRDKGSIYLVLDFCEHDLAGLLECKE
.||| .|| ||.| |..|.| ..  .|||||| |. ||.| |. .|||| .|  ..|.|||.| |.   .         ||.||...|| ||| ||.   
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHL------DSIFLVMQYCEQDLASLLDNMP

IKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGANQRYTNRVVTLWYRPPELFLGERNYGPPIDMWGAGCIMAE
  |. ...| || |.  .| |.| | ..|||.|  |.|.| || .|.|||||||.      .  | ..|||||| ||| || |.    |||| .|||..|
QPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPV-KPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGE

MWTRRPIMQGDTEQKQITLICQLCGSISPTEWAGVEKLEYYQKLELPQKENRKLKERLRHFVEDPYALDLIDKLLMLDPRKRIDADSTLEHDFF
.   .|.| |  | .|| .| .| |. | . | |  .|   |.  | ..    ||..     .    . |.. |.| .|.||  |. .||  .|
LLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQS--GRRLLNFLFMYNPKKRATAEECLESSYF

Kinase AqueK101.AA MAPK 19-312 30 1.3e-83 284.07 In-house 1-328 (328) Show / Hide
Range on Protein: 19-312
Range on HMM: 1-328/328
Sequence Identity: 30% (100 aa)

YEKLTKVGQGTFGEVFKAKDRK------TGRLVALKKVCMENEKEGFPMTALREIRILQLL-QHNNIVNLVEICRSKATPYNRDKGS------IYLVLDF
|. | ..||| .| |..|.|..      .|. ||.||.    ... .   ..|||..|. . .|.||..| .| . ..     | .|      ||.| ..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM-Q-D-DQNSLEEFNDIYIVMEL

CEHDLAGLLECKEIKFSLSEIKNIMQQLFNA--LAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKGANQRY-------------TNRVVTLW
.|.||  ....   . |   |. .| |. ..  | |||  |..||| | .||||.  ..||..|||||| .    ....             |  |.| |
METDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRW

YRPPELFLG--ERNYGPPIDMWGAGCIMAEMWT-RRPIMQGDTEQKQITLICQLCGSISPTEWAGVE-KLEYYQKLE----LPQKENRKLKERLRHFV--
|| ||. |.   ..|   .||| .|||.||| | |.|. .|.  . |..|| ...|. |.  .  ..   .... ..    ||..  . ... .   .  
YRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFN

EDPYALDLIDKLLMLDPRKRIDADSTLEHDFF
 .| |.||..|.| .|| |||...  |.| .|
ANPQAIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase AqueK101.AA Pkinase_Tyr 19-177 28 6.8e-21 71.38 Pfam 1-165 (270) Show / Hide
Range on Protein: 19-177
Range on HMM: 1-165/270
Sequence Identity: 28% (50 aa)

YEKLTKVGQGTFGEVFKAKDR----KTGRLVALKKV---CMENE--KEGFPMTALREIRILQLL-QHNNIVNLVEICRSKATPYNRDKGS--IYLVLDFC
 ... | |.| ||||.|.. .    .|.  || |..   .|. .  .| |    .||..|.  | .| |||.|. .|        .....  ||.|. ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT-------DQGEPNQIYIVMEYM

EH-DLAGLLECK---EIKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARAL-NKG
.| ||   |  .   . ....... .. .|  ....| . .|. |||    |.|||...  | .||||||.. |..
PHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD

Kinase AqueK101.AA TyrKc 19-245 19 6.3e-12 -29.86 SMART 1-280 (280) Show / Hide
Range on Protein: 19-245
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YEKLTKVGQGTFGEVFKAKDRKTGRLVALKKVCMENEKEGFPMTALREIRILQLL--QHNNIVNLVEICRSKATPYNRDK---GSIYLVLDFCEH-DLAG
 ... | | | ||||.|.. .   . || |..  .       .  .||.||.  |  .| |||.|. .|...           . ...|. ...| ||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKD

LLECKEIKFSLSEIKNIMQQLFNALAYIHGNNILHRDMKSCNILVTRKGELKLADFGLARALNKG-----ANQRYT-----NRV--VTLWYRPPELF---
 |  .. |.....  ... |  .  .|.| .|. |||    |.||....  | .||||.|..  .     . . |.     ..   . .   .|| .   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

--------------------LGERNYGPPIDMWGAGCIMAEMWT------RRPIMQG---------DTEQKQITLIC------------QLCGSI
                    .|.  |  .| .    .  .|.        |.|...           .|  || . |            ...  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF