Gene AqueK078 (A.queenslandica)

AqueK078

Species: A.queenslandica
Alias: AqueK078
External Links:
Annotation:

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
AqueK078.AA Protein None 905 None Fasta, JSON
AqueK078.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of AqueK078.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK078.AA Trio 67-313 30 1.2e-63 161.68 In-house 1-258 (258) Show / Hide 
Range on Protein: 67-313
Range on HMM: 1-258/258
Sequence Identity: 30% (81 aa)

YELLSGELGRGRFGIVRSCVSKVTGSAAAAKY----LKESHDVLQEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGGQLIDYILRMYNSLN
|. .  |.|||||..||.|. | || . |||     ..    |..|  .|..|.      |.|. . |. .|    ..|.| .|.| | ... |   |. 
YTFQE-EIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQ-----HPCVCSLHDTYETPRHYILILELCDDGELLCCLMRW-GSYC

ELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVA--PILKLTDFGSAQEVPYA---GLSVRPDLIEFSSPEVVFDDNVTKCTDLWS--------
|  .  |. |.|.|..| |   | |||.||||....   |  | .|. |||.||.   .    .  . .  || .||..  . |   || ||        
ESEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVM

-TGVSPFFHEYPSVSSQRLSRAQYDLSLQLFHSTSPQAIDFISALLKKQPAERLTAASALEHQWI
 .|.|||  | .     .. |  ....   | ..|  | .|| ..|  .|..| .|...|.|.| 
LSGISPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase AqueK078.AA CAMK 73-313 16 2.6e-53 169.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 73-313
Range on HMM: 1-425/425
Sequence Identity: 16% (71 aa)

ELGRGRFGIVRSCVSKVTG------------SAAAAKYLKES---------------------------------HDVLQEVKILRNLSSGPS--PSPHV
.||||.||.|. |. | |.               |.| .. .                                 . |..|..|...|...      |..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ILFIDALIT-------------------DENIVIIT---EVADGG----QLIDYILRMYN--------------SLNELLIVEYVKQLLSALDYIHERQI
| ....  .                   |.......   | ..||     | ||| .  .               ..|     |..|..||..|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHLDVKPENLLIASEVAP---------------ILKLTDFGSAQEVPYAG-------------------------LSVRPDLIEFSS-PEVVFD------
||.| ||||.|. .                    .|..||| |....                            .. .    |. . |||.        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DNVTKCTDLWSTGV---------SPFFHEYPSVSSQ-------------RLSRAQYDLSLQLFHSTS--------------------PQAID
        . ... .| || ||         .|| ... .   .             .  ...||     |  .|                    ....|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FISALLKKQPAERLTAASALEHQWI
.|. .|.. | .|.|.. .|.|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK078.AA S_TKc 68-313 26 2.1e-52 181.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 68-313
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

ELLSGELGRGRFGIVRSCVSKVTGSAAAAKYLKESHDVLQEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADG--GQLIDYILRMYNS-----
  .  ..|.| || |. |. | ||   | | .|   ....|..||..        |... ..|.  . ... ...| .||  | | ||| ..        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LNELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPILKLTDFGSAQEVPYAGLSVRPDLI---EFSSPEVVFDDNVTK-CTDLWSTGV----
..|  .  |..|...||.|.|...|.| |.||||.|. .     .|..|||.| ..          ..   .. .|||.     .|   | || |.    
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

----SPFFHEYPSVSSQRLSRAQYDLSLQLFHSTSPQAIDFISALLKKQPAERLTAASALE-------HQWI
     | |.             |... ...    ||.|.|||. .|.| |..|.||  ||.       |.|.
MLCGYPPFP-------------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK078.AA MLCK 67-252 34 3.2e-49 127.48 In-house 1-187 (257) Show / Hide 
Range on Protein: 67-252
Range on HMM: 1-187/257
Sequence Identity: 34% (67 aa)

YELLSGELGRGRFGIVRSCVSKVTGSAAAAKYLKESHDVLQE-----VKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGGQLIDYILRMYNSL
|. . .|||||.||||. |. | || . |||. |..... .|     . |.. |       | .|  .||  |....| | |  .|| | ..|.     |
YQIH-EELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLH-----HPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHL

NELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPILKLTDFGSAQEVPYAGL--SVRPDLIEFSSPEVVFDDNVTKCTDLWSTGV
.|. ...|..|.. .....|...|||||.|||| .. .     .|. ||| |...  ..    |     || .|||| .| |.  || ||.||
TEREVIHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGV
Kinase AqueK078.AA Pkinase 68-313 23 6.9e-48 170.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 68-313
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

ELLSGELGRGRFGIVRSCVSKVTGSAAAAKYLKESHDVL---------QEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGG----QLIDYI
  . . .|.| || |. |. | ||   | | .| .|.           .|..|...|.     .|... ..|.  .. .| ...| ..||     | |||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

L-RMYNSL--NELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIA--SEVAPILKLTDFGSAQ---EVPYAGLSVRPDLIEFSSPEVVF-DDNVTKCT
  ......   |  .  |..|.|..|.|.|.. |.| |.||||.||    ......|..|||.|    . ..  ....   ... .|||.  .   ..  
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DLWS---------TGVSPFFHE------YPSVSSQRLSRAQYDLSLQLFHSTS-----------------PQAIDFISALLKKQPAERLTAASALEHQWI
| ||         .|  || ..       . .  .|  ..... . .  .| |                 . ..|||. .|.| |..|.||. .|.| |.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK078.AA DRAK 71-313 30 4e-42 128.33 In-house 2-259 (259) Show / Hide 
Range on Protein: 71-313
Range on HMM: 2-259/259
Sequence Identity: 30% (81 aa)

SGELGRGRFGIVRSCVSKVTGSAAAAKYLKE-------SHDVLQEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGGQLID-YILRMYNSLN
..|.|||.| .|| |..| ||.  |||..|         ...|.|. .| .  .     |.||   .   |  ... . | | || . .  ..   . . 
AKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQD----CPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFC

ELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPI-LKLTDFGSAQEVPYAGLSVRPDLI---EFSSPEVVFDDNVTKCTDLWS---------
|  ..  ..| | .. | |.|.||||| || | | .||     .|. ||| .  .   |  || ..    ..  ||.   | .|  ||.||         
EKDVQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYI-CNGEEVR-EIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVML

TGVSPFFHEYPSVSSQRLSRAQYDLSLQLFHSTSPQAIDFISALLKKQPAERLTAASALEHQWI
|..|||  .         |    | |  .| . || |||||  |. ..| .|.|| . |.| |.
THISPFVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase AqueK078.AA Ciliate-E2 68-313 18 5.5e-41 138.42 In-house 1-365 (365) Show / Hide 
Range on Protein: 68-313
Range on HMM: 1-365/365
Sequence Identity: 18% (71 aa)

ELLSGELGRGRFGIVRSCVS-----------------------KVTGSAAAAKYLKES--HDVLQEVKILRNLSSG-----------PSPSPHVILFIDA
  .   .|.| ||.|. |                         ||...  | |..|..    ..|| .|.| . ..              .|..| ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LI--TDENIVIITEVADGGQLIDYILRMY----------NSLNELLIVEYVKQLLS---------------ALDYIHERQ-IVHLDVKPENLLIASEVAP
 .  .|.|| ...| ..|| | |||  ..          ....|  | .. ||.|.               || |.|..  |.| | ||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

ILKLTDFGSAQ----------------EVPYAG--LSVRPD----------------LIEFSSPEVVFDDN---------VTKCTDLWS---------TG
 .|..||| ..                . .. .   |. |                   .. .||..   .          ..  |.||         .|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

VSPFFHEYPSVSSQRLSRA-QYDLSLQL--------------FHSTSPQAIDFISA----LLKKQPAERLT-AASALEHQWI
  ||         |.     ..|.. .               ... |....|.|.     .|.|.| .|.| .  .|.|.|.
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK078.AA DAPK 70-252 32 1.2e-36 98.24 In-house 1-194 (264) Show / Hide 
Range on Protein: 70-252
Range on HMM: 1-194/264
Sequence Identity: 32% (64 aa)

LSGELGRGRFGIVRSCVSKVTGSAAAAKYLK-----ES------HDVLQEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGGQLIDYILR-M
 ..|||||.| .|| | .| ||.  |||..|      |       . . |. ||.....     |.||   ..  |   ...| | . || | ||..   
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRG----HPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDR

YNSLNELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPI--LKLTDFGSAQEVPYAGLSVRPDLI---EFSSPEVVFDDNVTKCTDLWSTGV
  .|.|   .. .|| | .. | | |.|.||| ||.| . ...  |   .|. ||| . ..  .|  .| |     |.  ||.|  .  .  ||.|| ||
EECLCEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKI-CNGEEFR-DIMGTPEYVAPEIVNYEPLSLATDMWSIGV
Kinase AqueK078.AA DAPK 70-313 30 1.6e-34 96.92 In-house 3-264 (264) Show / Hide 
Range on Protein: 70-313
Range on HMM: 3-264/264
Sequence Identity: 30% (83 aa)

LSGELGRGRFGIVRSCVSKVTGSAAAAKYLK-----------ESHDVLQEVKILRNLSSGPSPSPHVILFIDALITDENIVIITEVADGGQLIDYILRMY
   |.| | | .|. |  | ||   |||. |              |.  ||.||| ..      | .|   |.  .   .|.| |   || | |. |   
MGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRG----HPNIITLHDVYENKTDVVLILELVSGGELFDF-LCEK

NSLNELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPI--LKLTDFGSAQEVPYAGLSVRPDLI---EFSSPEVVFDDNVTKCTDLWSTGV-
 .|||    ...|| |... ..| ..|.|.| ||||       .|.   |. ||| | ..  .|  .. ...   ||  ||.|        || || || 
ECLNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRI-EPGNEFK-NIFGTPEFVAPEIVNYEPLGLETDMWSIGVI

--------SPFFHEYPSVSSQRLSRAQYDLSLQLFHSTSPQAIDFISALLKKQPAERLTAASALEHQWI
        |||  .         .. .|. . . | .||  | |||  || | |  |.| . .|.| ||
TYILLSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase AqueK078.AA Ciliate-E2-Unclassified 68-313 19 2.5e-34 116.5 In-house 1-352 (352) Show / Hide 
Range on Protein: 68-313
Range on HMM: 1-352/352
Sequence Identity: 19% (69 aa)

ELLSGELGRGRFGIVRSCVSKVTGSAAAAKYLKESHDVL--------------QEVKILRNLSSGP------------SPSPHVILFIDALITDENIVII
  .   .|.| ||.|. |. | .. ..| ||.| ....               .|.... . ..              .|.|... ....  ...|| |.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEVADGGQLIDYIL--------------RMYN--SLNELLIV-----EYVKQLLSALDYIHERQ-IVHLDVKPENLLIASEV-APILKLTDFGSAQEVPY
.| ..|| |..||               .|..   . |  ..      | .|.|..|.|.|. . |.| | ||||.|. ..     .|..|||.. .  .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

A------------------GLSVRPDLIEFS---SPEVVFDDNVT----KCTDLWS---------TGVSPFFHEYPSV----------------SSQRLS
                     ..   ..  .   .|||    |      .. | ||         .|  ||. .                      |   
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

RAQYDLSLQLF----HSTSPQAIDFIS----ALLKKQPAERLTAASALEHQWI
  ... . . .    .  ||.|.|||.     .|||.| .|.|.  .|.|.|.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK078.AA CAMKL 67-213 25 1.8e-29 91.13 In-house 1-176 (297) Show / Hide 
Range on Protein: 67-213
Range on HMM: 1-176/297
Sequence Identity: 25% (46 aa)

YELLSGELGRGRFGIVRSCVS-KVTGSAAAAKYLK--ESHD------------------VLQEVKILRNLSSGPSPSPHVILFIDALITDEN------IV
|...  .||.| || |. ..  . ||   | | ..     .                  . .|..|.. |.  ..  |..| . . . |.|.      |.
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN--IGKHPNIIKLYEVIETPEHDIETKKIY

IITEVADGGQ--LIDYIL-RMYNS--LNELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEV-APILKLTDFGSA
...| ..||   | |||  . .    . |     | .|..||..|.|.. ||| | ||||.|. .      .|..||| .
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFS
Kinase AqueK078.AA STE 69-213 22 3.4e-26 89.58 In-house 1-194 (359) Show / Hide 
Range on Protein: 69-213
Range on HMM: 1-194/359
Sequence Identity: 22% (45 aa)

LLS-GELGRGRFGIVRSCVSKV---------------TGSAAAAKYLK----------------------ESHDVLQEVKILRNLSSGPSPSPHVILFID
.   ...|.| || |  .. .                ||   | | ..                      |  ..|.|.||......    .|... ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH--M-HPNIVKYYG

ALITD-------ENIVIITEVADGGQLIDYILRMY---NSLN----------ELLIVEYVKQLLSA-LDYIHERQIVHLDVKPENLLIASEVAPILKLTD
. . .       ... |. |  ||| | | | . |   ..||          | .|  ...|.| . |.|.|. .|.| |.|| | |.        ||.|
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCD

FGSA
|| .
FGVC
Kinase AqueK078.AA DAPK 268-313 47 1.9e-18 47.16 In-house 219-264 (264) Show / Hide 
Range on Protein: 268-313
Range on HMM: 219-264/264
Sequence Identity: 47% (22 aa)

SRAQYDLSLQLFHSTSPQAIDFISALLKKQPAERLTAASALEHQWI
|.  || |  .| .||. |.|||  || | |  |.||...|.| ||
SQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase AqueK078.AA MLCK 283-313 48 6.9e-14 32.46 In-house 227-257 (257) Show / Hide 
Range on Protein: 283-313
Range on HMM: 227-257/257
Sequence Identity: 48% (15 aa)

SPQAIDFISALLKKQPAERLTAASALEHQWI
|. | |||| ||.| . .|.||. .|.| |.
SDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase AqueK078.AA TyrKc 68-313 16 3e-11 -40.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 68-313
Range on HMM: 1-280/280
Sequence Identity: 16% (50 aa)

ELLSGELGRGRFGIVRSCVSKVTGSAAAAKYLKESH--DVLQEVKILRNL--SSGPSPSPHVILFIDALITD-------ENIVIITEVADGGQLIDYILR
  |  .||.| ||.|. .. |      | | |||..  | ..| .|...|  .      |... .. . ...       | . |..| ...| | ||. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGH-----HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MYNSLNELLIVEYVKQLLSALDYIHERQIVHLDVKPENLLIASEVAPILKLTDFGSAQEVPYA---GLSVRPDLIEF----SSP----------EVVFDD
  . |.    ...  |  .  .|.|.....| |    | |....   . | .||| . ..      |  .. | .      ..           |. .. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECINYG

NVTKCTDLWS----------TGVSPFFH---EYPSVSSQRLSRAQYDLSLQLFHS--------TSPQAIDFISALLKKQPAERLTAASALEHQWI
  |  .| ||           | .|      . .   .. . . .    .   ..         ..   . ..   . .|..| | .    |. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AqueK078.AA STE 283-313 42 5.3e-08 24.48 In-house 327-359 (359) Show / Hide 
Range on Protein: 283-313
Range on HMM: 327-359/359
Sequence Identity: 42% (14 aa)

SPQAIDFISALLKKQPAERLTAASALE--HQWI
||  .|||.  |.| | .| ||   |.  | .|
SPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK078.AA CAMKL 283-313 29 1e-06 16.88 In-house 268-297 (297) Show / Hide 
Range on Protein: 283-313
Range on HMM: 268-297/297
Sequence Identity: 29% (9 aa)

SPQAIDFISALLKKQPAERLTAASALEHQWI
| ...|.|. .|.. | .| |.   ..| | 
S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase AqueK078.AA Pkinase_Tyr 67-187 22 0.016621 9.11 Pfam 1-134 (270) Show / Hide 
Range on Protein: 67-187
Range on HMM: 1-134/270
Sequence Identity: 22% (31 aa)

YELLSGELGRGRFGIVRSCVSK----VTGSAAAAKYLKE--------SHDVLQEVKILRNL-SSGPSPSPHVILFIDALI-TDEN--IVIITEVADGGQL
 ...  .||.| || |. .. |     |.   | | |||        . | ..|.||...| .      |... .. . .  .|   | |..| . .| |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH-----HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

IDYILRM---YNSLNELLIVEYVKQLLSALDYIHERQIVH
 ||  .     ..|.   ....  |  ....| ......|
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
I-set AqueK078.AA I-set 377-466 31 3.5e-13 47.25 Pfam 1-92 (92) Show / Hide 
Range on Protein: 377-466
Range on HMM: 1-92/92
Sequence Identity: 31% (29 aa)

PLFEGGTEEIQAPVGASVTIEWDYTGLPAPSVQWEHNERAVVP-SRRVQMSTIQ-GVTRLSIVELVKADEGTYTCCILNSLGSDIRNCALIV
| |.     ... .| ... | . || | |.|.| .... . | |.|.||.  . | ..| | .  ..|||.|||   ||.|..   . |.|
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV
IGc2 AqueK078.AA IGc2 389-456 26 3.2e-08 34.54 SMART 1-56 (56) Show / Hide 
Range on Protein: 389-456
Range on HMM: 1-56/56
Sequence Identity: 26% (18 aa)

PVGASVTIEWDYTGLPAPSVQWEHNERAVVPSRRVQMSTIQGVTRLSIVELVKADEGTYTCCILNSLG
  | |||.. . || |.|...| . .  .            .  .|.| .  ..|.|.|||   |. |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK078.AA IG 383-467 15 1.6e-05 25.58 SMART 1-58 (58) Show / Hide 
Range on Protein: 383-467
Range on HMM: 1-58/58
Sequence Identity: 15% (14 aa)

TEEIQAPVGASVTIEWDYTGLPAPSVQWEHNERAVVPSRRVQMSTIQGVTRLSIVELVKADE---GTYTCCILNSLGSDIR--NCALIVI
 . . . .| .||..  ..     ...|                       | | .. ..|.   |||.|      |..    .  |.| 
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
FN3 AqueK078.AA FN3 470-553 23 1.9e-13 51.93 SMART 1-69 (69) Show / Hide 
Range on Protein: 470-553
Range on HMM: 1-69/69
Sequence Identity: 23% (23 aa)

PAPPSS---VSGVLLGSS-----TSVLVSWLPPINDGHSPILHYSLDTRLVDDTDWSLVQERIDGAAYVVDDLLPG----KSYLFRVSSTNV--IGTS
| ||.    .. .  .|.     .|| .|| ||       |..|.                      |.|..| ||    . | |||.  |    | .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
S_TKc AqueK078.AA S_TKc 592-865 25 3.1e-50 174.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 592-865
Range on HMM: 1-231/231
Sequence Identity: 25% (74 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIKCSNDDQFSVALREFEMIKNVTHPRIASLEDAFRSENHVILVLQYVPG--GDLFNYITSSGP------
|||...||.|.|..|| |..  |.| .| | ||         ..|| .. |.  || |  | |.|.. .|. .|. |..|  |||| || . |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

IDERQSARYIRHILEGLEYLHNRNILLINIAPENLVLGVGLQEVKIIDFSHSKYLHSNPQLEILPQQINYLCMCTSTCIFIYLFNSFKLAPEALQCSPLA
..| . ..|.. |...|||.|...|.   . |||. |     ..||.||  .. |                    .|..    .    .||| |   .  
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------------------TTFCGTPWY----MAPEVL---GYG

L-STDLWSVGAVALFMLSGQCPFVSDTRDQLINNIHTLNINYKINPIIQRLSLDCTNMIFDGLLLTNESKRLSSHQCQR-------HRWL
  . | ||.| .   ||.|. ||   . ......|                | .. . . ...|  . .||..  .. .       | |.
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK078.AA Ciliate-E2-Unclassified 592-865 23 1.3e-46 159.76 In-house 1-352 (352) Show / Hide 
Range on Protein: 592-865
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YEIINEIGRGSFSVVYECTELTTDRPF-----AAKFIKCS-------NDDQFSVALREFEMI---------------KNVTHPRIASLEDAFRSENHVIL
|.||  ||.|.|..||.| .  ..  .     . |.....       . .    .......                .|  || |  ....|........
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VLQYVPGGDLFNYITSSGP-----------------IDERQSA-----RYIRHILEGLEYLHNRN-ILLINIAPENLVLGVGLQ--EVKIIDFSHSKYLH
|..|..||||..||....                  ..|.|..     .|...||.||||||  | |.  .| |||...  . .  ..|||||. ||.. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

SNPQLEILPQ----QINYLCMCTSTCIFIYLFNSFKLAPEALQCSPLALS----TDLWSVGAVALFMLSGQCPFVSDTRDQ----------------LIN
.|.. .   |    ||.. .|....|  ..  . . .||| ||      |     | ||.| .. .|| |..|| . ...|                |..
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMP-QYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

NIHTLNINYKINP------IIQRLSLDCTNMIFDGLLLTNESKRLSSHQCQRHRWL
||.  ||...  |      ...    |. | ..  .|  | .||..  |   | |.
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK078.AA Ciliate-E2 592-865 20 1.4e-46 157.92 In-house 1-365 (365) Show / Hide 
Range on Protein: 592-865
Range on HMM: 1-365/365
Sequence Identity: 20% (81 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIKCSN---------DDQFSVALREF-----EMIKNVTHPR-----------------------IASLED
|..|. ||.|.|..||.|.   ... || |.|.  .         .... .|.  .     |.||.. |                         |  . .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

AFR--SENHVILVLQYVPGGDLFNYITSS-----------GPIDERQSARYIRHILE---------------GLEYLHNRN-ILLINIAPENLVLGVGLQ
.|   ..|.. ||. |. ||||| || ..           ....|.. ......||.               .|||||..| |.  .| |||...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

EVKIIDFSHSKYLHSNPQLEILPQQINYLCMCTS-------TCIFIYLF------------NSFKLAPEALQCSPLA---------LSTDLWSVGAVALF
 .|||||  ||... . | ..   |.....|  .       ....   .            .   .||| |.  .            . |.||.| .  .
-IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD---QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MLSGQCPFVSDTRDQLINNIHTLNINYKINP-------------IIQRLSLDCTNMI--FDG--LLLTNESKRLS-SHQCQRHRWL
||.|. ||        ...|.  .|..  .              . . .|..| ..|  | |  .|  ...||..   |.  | |.
MLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF-GKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK078.AA MLCK 592-732 36 1.4e-45 117.69 In-house 1-143 (257) Show / Hide 
Range on Protein: 592-732
Range on HMM: 1-143/257
Sequence Identity: 36% (52 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIKC-SNDDQFSVALREFEMIKNVTHPRIASLEDAFRSENHVILVLQYVPGGDLFNYITSSG-PIDERQS
|.|. |.||| |..|. |.| .| . .||||||| .  |.  | ..|.|. .   ||..  . ||| . | ..... |. ||.|| .|. ..    ||. 
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENV-KNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREV

ARYIRHILEGLEYLHNRNILLINIAPENLVLGV-GLQEVKIIDF
..|.| |.||....| .||.  .. ||| ..      ..|||||
IHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDF
Kinase AqueK078.AA Trio 592-732 36 1.6e-40 101.08 In-house 1-143 (258) Show / Hide 
Range on Protein: 592-732
Range on HMM: 1-143/258
Sequence Identity: 36% (53 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIKCSNDDQFSVALREFEMIKNVTHPRIASLEDAFRSENHVILVLQYVPGGDLFNYITSSGPIDERQSAR
|.. .||||| ||||  |..  | | .|||||     |  .| ..| || ..  ||...|| |.. .  | ||.|   ..| |  .. . |   |.. . 
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQV-YHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKT

YIRHILEGLEYLHNRNILLINIAPENLVLGVGLQ---EVKIIDF
|.. .||.. ||||  ||   | |||. .  ..     .||.||
YMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDF
Kinase AqueK078.AA CAMK 597-732 20 2.4e-39 123.95 In-house 1-240 (425) Show / Hide 
Range on Protein: 597-732
Range on HMM: 1-240/425
Sequence Identity: 20% (50 aa)

EIGRGSFSVVYECTEL-TTD-----------RPFAAKFIKCS----------------------------NDDQFSVALREFEMIKN-------VTHPRI
..|||||..|..|..  ||            . .|.|.|. .                            ..      .|| |. |.       . || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ASLEDAFRS-------------------ENHVILVL---QYVPGG----DLFNYITSSGP---------------IDERQSARYIRHILEGLEYLHNRNI
 .| ... .                   ..|...|.    |..||    |||.||.. |.               ..||. .||.| |.....|.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LLINIAPENLVL-GVGLQE---------------VKIIDF
    . |||. |   .  .               .|||||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase AqueK078.AA Pkinase 592-709 34 2.5e-33 118.91 Pfam 1-130 (293) Show / Hide 
Range on Protein: 592-709
Range on HMM: 1-130/293
Sequence Identity: 34% (45 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIKCSNDDQ--FSVALR--EFEMIKNVTHPRIASLEDAFRSENHVILVLQYVPGG----DLFNYIT--SS
|.|.  ||.|||..||.|..  | . .| | || ....      ..|  | .. |.. || |  | |.|....|. .|. |..||    ||| ||.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPI--DERQSARYIRHILEGLEYLHNRNIL
|..  .|..  .|.. ||.||||.|...|.
GCFYFSEWECKFYMYQILRGLEYCHSMGII
Kinase AqueK078.AA DAPK 594-732 33 1.1e-30 81.5 In-house 1-151 (264) Show / Hide 
Range on Protein: 594-732
Range on HMM: 1-151/264
Sequence Identity: 33% (50 aa)

IINEIGRGSFSVVYECTELTTDRPFAAKFIK--CSNDD----QFSVALREFEMIKNVT-HPRIASLEDAFRSENHVILVLQYVPGGDLFNYITS--SGPI
.  |.||| |.||  |..  | . .||||||   .  .         ..|    ...  ||.. .| ...     |||.| || || ||.|.        
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

DERQSARYIRHILEGLEYLHNRNILLINIAPENLVLGV-GLQE--VKIIDF
.| . .| .. ||||. ||| |||    . |.|  |   . ..  .|||||
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDF
Kinase AqueK078.AA CAMKL 592-708 27 1.8e-28 87.89 In-house 1-148 (297) Show / Hide 
Range on Protein: 592-708
Range on HMM: 1-148/297
Sequence Identity: 27% (40 aa)

YEIINEIGRGSFSVVYECTE-LTTDRPFAAKFIK--CSNDDQFSVAL-------------REFEMIKNVT---HPRIASLEDAFRSENH------VILVL
|.|. ..|.|||..|  .|  .|| .  | |.|.    ..|... .              || .  | .    || | .| . .  ..|      . ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

QYVPGGD--LFNYITSS----GPIDERQSARYIRHILEGLEYLHNRNI
 |..||.  ||.|| .     |...|..  || | |.....|.|...|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGI
Kinase AqueK078.AA STE 592-738 20 2.7e-22 75.63 In-house 1-197 (359) Show / Hide 
Range on Protein: 592-738
Range on HMM: 1-197/359
Sequence Identity: 20% (44 aa)

YEIINEIGRGSFSVVYECTELT---------------TDRPFAAKFIKCSND-----------------DQFSVALREFEMIKNVT--HPRIASLEDAFR
.|.| .||.|.| .|| .                   | . .| | .. .|.                 ...   |.| .. |.    || |    ... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SE-------NHVILVLQYVPGGDLFNYITSS--------------GPIDERQSARYIRHILEG-LEYLHNR----------NILLINIAPENLVLGVGLQ
 |       ... ... |..|| |   | .               ....| | |...| ||.| |.|||.           ||||               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

EVKIIDFSHSKYL
 ||..|| ... |
-VKLCDFGVCGQL
Kinase AqueK078.AA DRAK 596-738 33 3.8e-21 61.97 In-house 3-152 (259) Show / Hide 
Range on Protein: 596-738
Range on HMM: 3-152/259
Sequence Identity: 33% (50 aa)

NEIGRGSFSVVYECTELTTDRPFAAKFIKCSNDDQFSVA--LREFEMIKN-VTHPRIASLEDAFRSENHVILVLQYVPGGDLFN--YITSSGPIDERQSA
 | ||| | ||  | .  | . |||||.|     | . .  |.|     . .  |..  | . .     .|||| |  || .|.         . |..  
KERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKDVQ

RYIRHILEGLEYLHNRNILLINIAPENLVLG--VGLQEVKIIDFSHSKYL
| .| ||||. |||.|||      | |  |     . ..||.||  | |.
RCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYI
Kinase AqueK078.AA DAPK 636-732 30 1.6e-20 55.82 In-house 51-151 (264) Show / Hide 
Range on Protein: 636-732
Range on HMM: 51-151/264
Sequence Identity: 30% (31 aa)

REFEMIKNVT-HPRIASLEDAFRSENHVILVLQYVPGGDLFNYITSSGPIDERQSARYIRHILEGLEYLHNRNILLINIAPENLVL-GVGLQE--VKIID
||    . .  || | .| |..     |.|.|  | || || ..     ..|   . .|  ||.|. ..| ..|    . |||  |   . ..  .||||
REVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKECLNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIID

F
|
F
Kinase AqueK078.AA DRAK 772-865 29 7.6e-17 48.35 In-house 168-259 (259) Show / Hide 
Range on Protein: 772-865
Range on HMM: 168-259/259
Sequence Identity: 29% (28 aa)

LAPEALQCSPLALSTDLWSVGAVALFMLSGQCPFVSDTRDQLINNIHTLNINYKINPIIQRLSLDCTNMIFDGLLLTNESKRLSSHQCQRHRWL
.||| |.  |. ..||.||.| ..  ||..  ||| |..     ||  .|. |  .     .|   .  |   |.  .  .|..  .|  | ||
VAPEILNYDPITMATDMWSIGVLTYVMLTHISPFVGDDKQETFLNISQCNLDYSEE-MFSCHSPVAIDFI-QSLCVIKPEDRMTAEECLDHPWL
Kinase AqueK078.AA CAMK 773-865 17 5.8e-14 40.67 In-house 288-425 (425) Show / Hide 
Range on Protein: 773-865
Range on HMM: 288-425/425
Sequence Identity: 17% (25 aa)

APEALQC--------------SPLALSTDLWSVGAVALFMLSGQCPFVSDTRDQLI---------NNIHTLNINYKINPIIQRLSL--------------
||| |.                .   ..| ||.| .  .||.|  || .|.... .         ....   .. | . .   .|               
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

---------DCTNMIFDGLLLTNESKRLSSHQCQRHRWL
         .| ..|  ..| .. .||.. .|| .| |.
DEFHHFVSQECKDLI-RKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK078.AA MLCK 772-865 30 3.4e-13 30.59 In-house 166-257 (257) Show / Hide 
Range on Protein: 772-865
Range on HMM: 166-257/257
Sequence Identity: 30% (29 aa)

LAPEALQCSPLALSTDLWSVGAVALFMLSGQCPFVSDTRDQLINNIHTLNINYKINPIIQRLSLDCTNMIFDGLLLTNESKRLSSHQCQRHRWL
.|||  .  |. ..|| |||| ..  .|||  ||  |.  . .||.   .  .. . .    | ...  | . ||  . .||.. |.| .|.||
VAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFMGDNDRETMNNVTSCEWDFDDECFDD-ISDEAKDFI-SRLLVKDKEKRMTAHECLQHPWL
Kinase AqueK078.AA DAPK 772-811 47 3.5e-13 32.34 In-house 173-212 (264) Show / Hide 
Range on Protein: 772-811
Range on HMM: 173-212/264
Sequence Identity: 47% (19 aa)

LAPEALQCSPLALSTDLWSVGAVALFMLSGQCPFVSDTRD
.||| ..  || |.||.||.| ..  ||||  ||. ||..
VAPEIVNYEPLSLATDMWSIGVITYIMLSGISPFLGDTKQ
Kinase AqueK078.AA Trio 773-808 44 7.8e-11 23.34 In-house 168-203 (258) Show / Hide 
Range on Protein: 773-808
Range on HMM: 168-203/258
Sequence Identity: 44% (16 aa)

APEALQCSPLALSTDLWSVGAVALFMLSGQCPFVSD
||| .| .|  . || ||.|...  ||||  ||...
APEIIQGNPVSYGTDIWSIGVLTYVMLSGISPFYDE
Kinase AqueK078.AA DAPK 773-817 44 5.1e-10 24.99 In-house 174-218 (264) Show / Hide 
Range on Protein: 773-817
Range on HMM: 174-218/264
Sequence Identity: 44% (20 aa)

APEALQCSPLALSTDLWSVGAVALFMLSGQCPFVSDTRDQLINNI
|||     || | || ||.| .   .|||  ||  ||..  . ||
APEIVNYEPLGLETDMWSIGVITYILLSGASPFLGDTKQETLANI
Kinase AqueK078.AA DAPK 592-624 51 1.1e-09 24.01 In-house 1-33 (264) Show / Hide 
Range on Protein: 592-624
Range on HMM: 1-33/264
Sequence Identity: 51% (17 aa)

YEIINEIGRGSFSVVYECTELTTDRPFAAKFIK
|..  ||| | |.||  |.|  |   .||||||
YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIK
Kinase AqueK078.AA Pkinase_Tyr 592-708 24 4.9e-09 31.24 Pfam 1-132 (270) Show / Hide 
Range on Protein: 592-708
Range on HMM: 1-132/270
Sequence Identity: 24% (32 aa)

YEIINEIGRGSFSVVYECTEL----TTDRPFAAKFIKCSNDDQ---FSVALREFEMIKNV-THPRIASLEDAFR-SENH--VILVLQYVPGGDLFNYITS
 ... ..|.|.| .||..|       |. | | | .| . ...       .|| .. |.   || | .|  .    . .  ...|. |.|.||| .|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----SGPIDERQSARYIRHILEGLEYLHNRNI
     .|..  .   . . | .|.|||...|.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNC
Kinase AqueK078.AA CAMKL 786-865 29 2.4e-07 19.32 In-house 217-297 (297) Show / Hide 
Range on Protein: 786-865
Range on HMM: 217-297/297
Sequence Identity: 29% (25 aa)

TDLWSVGAVALFMLSGQCPFVSDT----RDQLINNIHTLNINYKINP-IIQRLSLDCTNMIFDGLLLTNESKRLSSHQCQRHRWL
.| || | .  .|. |. ||  ||     .  | . .  ..    .| |  ..| || ..|  ..| .| .|| . ||  .|.|.
VDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLI-RKMLQVNPEKRPTIHQIMNHPWM
Kinase AqueK078.AA Pkinase 772-865 20 4.7e-05 18.95 Pfam 178-293 (293) Show / Hide 
Range on Protein: 772-865
Range on HMM: 178-293/293
Sequence Identity: 20% (24 aa)

LAPEALQ-CSPLALSTDLWSVGAVALFMLSGQCPFVSD------TRDQLINNIHTLNINYKINPIIQRL----------------SLDCTNMIFDGLLLT
.||| .. ...   . | ||.| .   ||.|. || ..      . .|.|..|    . . .   . .                 | .|   | ...|  
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI-KWCLCK

NESKRLSSHQCQRHRWL
. .||.. .|.  | |.
DPKKRPTAEQILQHPWF
Kinase AqueK078.AA STE 773-865 16 0.003104 7.42 In-house 230-359 (359) Show / Hide 
Range on Protein: 773-865
Range on HMM: 230-359/359
Sequence Identity: 16% (21 aa)

APEALQC------SPLALSTDLWSVGAVALFMLSGQCPFVSDTRDQLINNIHTL----------NINYKINPIIQ--------------------RLSLD
||| .|.      ..   . | ||.| ... |. |. |.   .  . . .| .           .|...  | ..                    ..| .
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE

CTNMIFDGLLLTNESKRLSSHQCQR--HRWL
. . | .  |  . .|| ...|  .  | ..
FKDFI-NKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK078.AA DAPK 845-865 33 0.060379 0.81 In-house 244-264 (264) Show / Hide 
Range on Protein: 845-865
Range on HMM: 244-264/264
Sequence Identity: 33% (7 aa)

LLLTNESKRLSSHQCQRHRWL
||  .  ||..  .| .| |.
LLVKDPEKRMTAEECLQHPWI