Gene AqueK012 (A.queenslandica)

AqueK012

Species: A.queenslandica
Alias: AqueK012
External Links:
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK012.AA Protein None 485 None Fasta, JSON
AqueK012.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of AqueK012.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK012.AA PDK1 27-293 48 5.1e-165 509.88 In-house 1-307 (307) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-307/307
Sequence Identity: 48% (155 aa)

FNFDRIIGEGSYSTV------SS-------CALVKILDKRHIIKEKKVQYVSREKDVLARID-----HPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYL
| | ..|||||||||      ..       .| .||. ||.||.|||| ||.|||.......     ||..|||||||||  .|||.|.....|.|| |.
FIFGKNIGEGSYSTVYLAREKETKNDENKMYA-IKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYM

RK--VGAFDENATRFYTSEIVIALEYLHGKGIIHRDLKPENILLNKDMHIQITDFGTA---KIFES---------------DED----------EKASSF
.|  .| ||.  .|||..||..|||.||..||||||||||||||.|||||.|||||||   ||..                . .           ...||
KKQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSF

VGTAEYVSPELLQSKVAYKSSDLWALGCIIYQFLAGRPPFHAA--YVNYTCSPPLFIMCRNEYLCFQKIIKHEYSIPDG--FPDNAKDLVENLLVSDPTK
||||||||||||. | . .|.|.|||||||||..||.||| ..    |            |||. ||||.| .|..||.  || .|||||..||| ||..
VGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATN------------NEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPND

RLG-CDKMGGYPPLKAHYFF
||. || .|||...||| ||
RLTSCDECGGYQQIKAHPFF
Kinase AqueK012.AA AGC 27-293 29 3.6e-131 341.07 In-house 1-395 (395) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-395/395
Sequence Identity: 29% (120 aa)

FNFDRIIGEGSYSTVSSCAL--------------VKILDKRH-IIKEK--KVQYVSRE------------KDVLARID----------HPFFVK-LYFTF
|.| ..||.||...|  .                .|.|.|.| |.. |  .|... .|            ...|....          ||| || |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDKDN--LYFGLSFAE---------QG-ELLDYLR---KVGAFDENATRFYTSE-------IVIALEYLHG-KGIIHRD-LKPENILLNKDMHIQITDFG
||||.  ||| . ...          | ||. .|.   | | |||...|||..|       || ||||||  .|||||| ||||||||..| || .||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TAKIFESDE-------------------------------------------------DEKASSFVG--TAEYVSPELLQSKVAYKSSDLWA--LGCIIY
 .|.. .|.                                                 ......|.|  |.||..|| |      |. | |.  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QFLAGRPPFHAA---YVNYTCSPPLFIMCR----NEYLCFQKII------KHEYSIP----------DGFPDNAKDLVENLLVSDPTKRLGCDKMG----
..|.|.|||..      |           |    |..  ||||.      ...  .|          . | ..||||.. ||. ||.||||| . .    
EMLTGYPPFYGDNPQE-N-----------RHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDK

GYPPLKAHYFF
|.  .|.| .|
GAEEIKNHPWF
Kinase AqueK012.AA S_TKc 27-287 33 1e-81 278.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-287
Range on HMM: 1-231/231
Sequence Identity: 33% (93 aa)

FNFDRIIGEGSYSTVSSCALVKILDKRHIIKEKKVQYVSREKDVLARIDHPFFVKLYFTFQDKDNLYFGLSFAEQ--GELLDYLRKVGA------FDENA
. . |.||.|....|  |  .|  ...  ||. | . . || ..| . .||. |||| .||| |.||. . ....  |.|.||..| |       |.|  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

TRFYTSEIVIALEYLHGKGIIHRDLKPENILLNKDMHIQITDFGTAKIFESDEDEKASSFVGTAEYVSPELLQSKVAYKSSDLWALGCIIYQFLAGRPPF
.|||. .|. ||||.| .||||||||||||||..  || |.||| |...        ..|.|| .|..||.|  .  ....| |..|||.| .|.|.|||
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPF

HAAYVNYTCSPPLFIMCRNEYLCFQKIIKHEYSIPDGFPDNAKDLVENLLVSDPTKRLGCDKMGG-------YPPL
.                 .... |.||           .. |||.....|. ||.||... .           | .
P-----------------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK012.AA RSK 29-293 32 4.3e-76 259.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 29-293
Range on HMM: 1-278/278
Sequence Identity: 32% (95 aa)

FDRI--IGEGSYSTVSSCA--------LVKILDKRHIIKEKK-VQYVSREKDVLARID-HPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYLRKVGA---
      .| |.....  |          .|.|.|. |.. .| . .. .| ..|.|.  ||| |.|. .||... ||  . . . |||.. |.| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDENATRFYTSEIVIALEYLHGKGIIHRDLKPENILLNK---DMHIQITDFGTAKIFESDEDEKASSFVGTAEYVSPELLQ---SKVAY-KSSDLWALGC
|.|.  .|| .||| |.|.|| .|||||||||||||..    . || .|||| .|.|  |. ... .|..|.||. ||.|     .... |. |.| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IIYQFLAGRPPFHAAYVNYTCSPPLFIMCRNEYLCFQKIIKHE--YSIP--DGFPDNAKDLVENLLVSDPTKRLGCDKMGGYPPLKAHYFF
..|  |.|.|||..                |    ...| | .   ..|  .   ..||||.  .|  || ||||| .. .   .|.| .|
LMYEMLTGCPPFQG-PND-----------NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQ-DAEEIKQHPWF
Kinase AqueK012.AA Ciliate-E2 27-293 21 1.1e-72 247.73 In-house 1-365 (365) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-365/365
Sequence Identity: 21% (87 aa)

FNFDRIIGEGSYSTVSSCAL-------------------------------VKILDKRHIIKEKKVQYVSREKD----------VLARIDHPFFVKLYFT
..| ..||.|....|  |                                 .||. |. |.  |..... ||..          .| ...||. .|.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DKDNLYFGLSFAEQGELLDYLR-------------------KVGAFDENATR-------FYTSEIVIALEYLHGKG-IIHRDLKPENILLNKDMHI
||  |..|.|. . ....|.|.||..                   ... . .  ..       ||  .|. |||||| |. |||||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

QITDFGTAKIFESDED------------------------------EKASSFVGTAEYVSPELLQSKVAY---------KSSDLWALGCIIYQFLAGRPP
 |.|||..|..  |..                              . . ...||..|..|| |..|  .         ...|.|.||.|.|..| |.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FHAAYVNYTCSPPLFIMCRNEYLCFQKIIKHEYSIP------------------DGFPDNAKDLVEN----LLVSDPTKRLGCDKMGGYPPLKAHYFF
|                       .|.|.. ....|                  .  ....|||  .    .|. || ||..     |.  .. | .|
F-----------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-----GWEQILNHPWF
Kinase AqueK012.AA Pkinase 27-293 29 2.3e-69 241.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

FNFDRIIGEGSYSTVSSC--------ALVKILDKRHIIKEKKVQYVS-REKDVLARIDHPFFVKLYFTFQDKDNLYFGLSFAEQG----ELLDYLR--KV
. . |.||.||...|  |          |||..|||. ..|... .  .|  ...|..||. |.|| .|.|||..|. . ..| |    .| ||..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAF--DENATRFYTSEIVIALEYLHGKGIIHRDLKPENILLNKDMHI----QITDFGTAKIFESDEDEKASSFVGTAEYVSPELLQ-SKVAYKSSDLWAL
|.|  .|.  .||  .|. .|||.| .|||||||||||||.....||     |.||| || |.   .. ...|.|| .|..||... ..   ...| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIIYQFLAGRPPFHAAYVNYTCSPPLFIMCRNEYLCFQKIIKHEYSIPDGFP---------------------DNAKDLVENLLVSDPTKRLGCDKMGG
|||.|..| |||||  .  .        .  .... ....| . ... .   .                     ...||.....|  ||.||..      
GCILYEMLCGRPPFPGHC-WH-------DN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT------

YPPLKAHYFF
 . .. | .|
AEQILQHPWF
Kinase AqueK012.AA CAMK 32-279 22 3.4e-69 221.89 In-house 1-417 (425) Show / Hide 
Range on Protein: 32-279
Range on HMM: 1-417/425
Sequence Identity: 22% (95 aa)

IIGEGSYSTVSSCALV--------------------KILDKRHIIK-------------------------EKKVQYVSREKDVLAR-------IDHPFF
..|.||...|  |                       ||.||. . .                         .|. . | || ... .       .|||  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYFTFQD-------------------KDNLYFGL---SFAEQGEL----LDYLRKV---------------GAFDENATRFYTSEIVIALEYLHGKGI
.||| ...|                   ....|. .    ... |||    .||...                | |.|  .|.|   |. |..|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENILLNKDM-----------------HIQITDFGTAKIFESDE----------------------DEKASSFVGTAEYVS-PELLQS------
.|||||||||||....                  | |.||| |..|...|                      ..| . |.|| ||.. ||.|..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KVAY-KSSDLWALGCIIYQFLAGRPPFHAAYVNYTCSPPLFIMCR---NEYLCFQKIIKHEYS-IPDGFPD----------------------
       |  | ...| |..|.| |  | |.||| . . | .|.       .   |.|  |.||.| .|. .|. |..                      
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D---E-WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

-NAKDLVENLLVSDPTKRLGCD
  .|||. ..|. ||.||. ..
QECKDLIRKMLQVDPEKRMTIE
Kinase AqueK012.AA Akt 48-220 43 3.4e-67 213.84 In-house 31-205 (264) Show / Hide 
Range on Protein: 48-220
Range on HMM: 31-205/264
Sequence Identity: 43% (76 aa)

KILDKRHIIKEKKVQYVSREKDVLARIDHPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYLRKVGAFDENATRFYTSEIVIALEYLHGKGIIHRD-LKPE
|.| |..||. ..|...  |. .| ...||| |.|.. ||..|.||| . ..  |||  .|.. . |.|. .||| .||. |.|.|| |.|| || ||||
KVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPE

NILLNKDMHIQITDFGTAKIFESDEDEKASSFVGTAEYVSPELLQSKVAYKSSDLWA-LGCIIYQFLAGRPPFHA
|||. || || .|||| .|     ...|. .| ||.|| .|| |. . . |..| |. |||..| .. |||||..
NILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYN
Kinase AqueK012.AA AktR 48-218 45 1.7e-66 227.23 In-house 31-205 (268) Show / Hide 
Range on Protein: 48-218
Range on HMM: 31-205/268
Sequence Identity: 45% (79 aa)

KILDKRHIIKEKKVQYVSREKDVLA-RIDHPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYLRKVGAFDENATRFYTSEIVIALEYLHGK-GIIHRDLKP
|...| .||.... ... .|.....  ..|||.|||...||.|..|.| ... . |||...|.| . |.|. .||| ..|..|||||| .  || |||||
KMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKP

ENILLNKDMHIQITDFGTAK-IFESDEDEKASSFVGTAEYVSPELLQS-KVAYKSSDLWALGCIIYQFLAGRPPF
||||| .| |. ||||| .|  |  ..|||| ||.|| ||..|| ..  |   ||.|.||.|. ||  ..| |||
ENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPF
Kinase AqueK012.AA Ciliate-E2-Unclassified 27-293 23 1.5e-65 224.1 In-house 1-352 (352) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-352/352
Sequence Identity: 23% (86 aa)

FNFDRIIGEGSYSTVSSC-------------ALVKILDKRHIIKEKKVQYVSREKDVLAR------------------IDHPFFVKLYFTFQDKDNLYFG
... ..||.|....|  |             . ... .|...|..|. ...  .| .  .                  ..||| ||....||||.|.|. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LSFAEQGELLDYLRKVGA-----------------FDENATR-----FYTSEIVIALEYLHGKG-IIHRDLKPENILLNKDM---HIQITDFGTAKIFES
. ..|.|.|..|..| .                  |.|....     ||. .|. .||||| |. |||||.||||||.....   .| |.||| .|  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D--------------EDEKASSFVGTAEYV----SPELLQSKVAY----KSSDLWALGCIIYQFLAGRPPFHAAYVNY-TCSPPLFIMC---RNEYLCFQ
.               ......|.|| .|     .||.||..  .    ...| |.||.|.|..| |..|| .   .   ..   .| .   | ...  .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNI

K-----IIKHEY-SIPDGFPDNAKDLVE----NLLVSDPTKRLGCDKMGGYPPLKAHYFF
|     . |..  .||.. ...|||...     .|. .| ||.      ... .. | .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI------TFEQILNHPWF
Kinase AqueK012.AA SGK 47-218 41 1.8e-64 197.81 In-house 47-225 (283) Show / Hide 
Range on Protein: 47-218
Range on HMM: 47-225/283
Sequence Identity: 41% (76 aa)

VKILDKRHII-------KEKKVQYVSREK-DVLARIDHPFFVKLYFTFQDKDNLYFGLSFAEQGELLDYLRKVGAFDENATRFYTSEIVIALEYLHGKGI
.|.| | |||       | |.. ..  |. ..|  . ||| |.| . || |. ||| . ... ||.  .|.. . | |   |||..||| |||||| . |
MKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDI

IHRDLKPENILLNKDMHIQITDFGTAK--IFESDEDEKASSFVGTAEYVSPELLQSKVAYKSSDLWALGCIIYQFLAGRPPF
|.||||||||||  . |. .|||| .|  | ..|.    ..| || ||  || |. .   .. | | |||. | .. | |||
IYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDT---TFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPF
Kinase AqueK012.AA PKA 48-218 49 8.8e-63 214.89 In-house 30-199 (263) Show / Hide 
Range on Protein: 48-218
Range on HMM: 30-199/263
Sequence Identity: 49% (86 aa)

KILDKRHIIKEKKVQYVSREKDVLARIDHPFFV-KLYFTFQDKDNLYFGLSFAEQGELLDYLRKVGAFDENATRFYTS-EIVIALEYLHGKGIIHRDLKP
|.|.|. |...| |. |  || .|  |.||| | |.|.|||| ..||. . ... ||. .||||.| |..  ..||   .|| |||||| . ||.|||||
KMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKP

ENILLNKDMHIQITDFGTAKIFESDEDEKASSFVGTAEYVSPELLQSKVAY-KSSDLWALGCIIYQFLAGRPPF
||||..|. ||.||||| ||  ..      ..  || ||  || .|||  . || | ||||..|| .||| |||
ENILIDKNGHIKITDFGFAKKVDD----RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF
Kinase AqueK012.AA TyrKc 27-292 19 3.1e-11 -41.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-292
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

FNFDRIIGEGSYSTVSSCAL-----VKILDKRHIIKEKKVQYVSREKDVLARI--DHPFFVKLY-FTFQDK------DNLYFGLSFAEQGELLDYLRKVG
  .....||| . .|  . .     || | . .      ..   ||  .. ..  .||  |.||    |..      . |.  . ... | |.||||| .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

A-FDENATRFYTSEIVIALEYLHGKGIIHRDLKPENILLNKDMHIQITDFGTAKIFESD------EDEKASSFVGTAE------YVSPELLQSKVAYKSS
  .       .   |    |||| |..|||||   |.|.... .. |.||| ..  ..|      .| . ..  . .         .|| .. ..    |
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DLWALGCIIYQFLAGRPPFHAAYVNYTCSPPLFIM----CRNEYLCFQKIIKHEYSIPDG--------FPDNAKDLVENLLVSDPTKRLGCDKMGGYPPL
| |. |  ..  .              . .|   |    . |. .  .    .   .|.          ||   .. .     || .|            
DVWSFGVCMWEIFTY------------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------

KAHYF
  ..|
-HECF
Kinase AqueK012.AA SGK 235-293 35 5.1e-10 26.64 In-house 227-283 (283) Show / Hide 
Range on Protein: 235-293
Range on HMM: 227-283/283
Sequence Identity: 35% (21 aa)

CRNEYLCFQKIIKHEYSIPDGFPDNAKDLVENLLVSDPTKRLGCDKMGGYPPLKAHYFF
.||  . ...||. .  || ..   |.|| . ||  ||.||||  .  .    | | ||
SRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKR--DFMEIKNHPFF
Kinase AqueK012.AA PKA 242-293 36 2e-09 37.67 In-house 210-263 (263) Show / Hide 
Range on Protein: 242-293
Range on HMM: 210-263/263
Sequence Identity: 36% (20 aa)

FQKIIKHEYSIPDGFPDNA---KDLVENLLVSDPTKRLGCDKMGGYPPLKAHYFF
..||.....  |  |  .|   |||...||. |.|||.|. |  |    | | .|
YEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKN-GVNDIKNHKWF
Kinase AqueK012.AA Akt 242-293 35 1.1e-08 23.8 In-house 212-264 (264) Show / Hide 
Range on Protein: 242-293
Range on HMM: 212-264/264
Sequence Identity: 35% (19 aa)

FQKIIKHEYSIP--DGFPDNAKDLVENLLVSDPTKRLGCDKMGGYPPLKAHYFF
|.||   .. .|  | . ...|||.. ||  ||.||||  . ..   .|.| .|
FKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGG-GPNDAQEIKRHPWF
Kinase AqueK012.AA Pkinase_Tyr 98-162 34 3e-06 21.69 Pfam 88-156 (270) Show / Hide 
Range on Protein: 98-162
Range on HMM: 88-156/270
Sequence Identity: 34% (24 aa)

FAEQGELLDYLRK----VGAFDENATRFYTSEIVIALEYLHGKGIIHRDLKPENILLNKDMHIQITDFG
... | |||||||     ....      .  .|  ..|||. |..|||||   |.|....... |.|||
YMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase AqueK012.AA AktR 242-293 35 1.9e-05 17.43 In-house 214-268 (268) Show / Hide 
Range on Protein: 242-293
Range on HMM: 214-268/268
Sequence Identity: 35% (20 aa)

FQKIIKHE-YSIPDG--FPDNAKDLVE-NLLVSDPTKRLGCDKMGGYPPLKAHYFF
||||....  ..|.   | ...|||..  ||  .|.||||  ..|    .| | .|
FQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWE-EIKSHPWF
Kinase AqueK012.AA AktR 27-41 26 0.010953 6.69 In-house 1-15 (268) Show / Hide 
Range on Protein: 27-41
Range on HMM: 1-15/268
Sequence Identity: 26% (4 aa)

FNFDRIIGEGSYSTV
| . ...|.| ...|
FHVYKCLGKGAFGKV
Kinase AqueK012.AA SGK 27-38 50 0.123281 0.29 In-house 1-12 (283) Show / Hide 
Range on Protein: 27-38
Range on HMM: 1-12/283
Sequence Identity: 50% (6 aa)

FNFDRIIGEGSY
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FDFLKVIGKGSF
PDK1_PH AqueK012.AA PDK1_PH 380-479 56 5.2e-57 195.71 In-house 1-112 (112) Show / Hide 
Range on Protein: 380-479
Range on HMM: 1-112/112
Sequence Identity: 56% (63 aa)

STWHPFV--NGELIIKTGLVDKRKGMFS----KRRQLILTDAPRLYYVDPVAMVLKGEIPWS-SNIKIEQK-----NFKIFFVHTPNRTYYLEDPTGSAK
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TPWHQFLMPEGEHILKCGWVYKRKGLFAKPKKKRRQLILTDGPRLFYVDPMTMVIKGEIPWSSKDLYVEYKPDRKNNFKHFFIHTPNRTYYFEDPKGCAN

KWVETLNKSLVL
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KWCEAIEKVCKR