Gene AqueK010 (A.queenslandica)

AqueK010

Species: A.queenslandica
Alias: AqueK010
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: LATS

Sequence

Name Sequence Type Origin Length Description Download
AqueK010.AA Protein None 833 None Fasta, JSON
AqueK010.kin_dom Protein Kinase Domain None 306 None Fasta, JSON

Protein domain

Protein domains of AqueK010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
UBA AqueK010.AA UBA 116-153 33 6.1e-07 28.79 Pfam 1-38 (38) Show / Hide 
Range on Protein: 116-153
Range on HMM: 1-38/38
Sequence Identity: 33% (13 aa)

VDQDMLHELIMK-GYDQNSCIAALIQCNSHSVEAALDVL
.|..|. .|.   |.. . |. || .||  .||.|.. |
IDEEMVKQLMEMTGFSMMQCKKALRACNN-NVERAVEWL
UBA AqueK010.AA UBA 117-155 33 0.00018 22.1 SMART 1-38 (38) Show / Hide 
Range on Protein: 117-155
Range on HMM: 1-38/38
Sequence Identity: 33% (13 aa)

DQDMLHELIMKGYDQNSCIAALIQCNSHSVEAALDVLMS
..  ...|.  |.|.. |..|| .||   ||.|...|.|
YEEKIDQLMEMGFDREECVQALRACNWN-VEMAMNWLFS
Kinase AqueK010.AA NDR 394-699 51 3.5e-208 649.06 In-house 1-350 (350) Show / Hide 
Range on Protein: 394-699
Range on HMM: 1-350/350
Sequence Identity: 51% (183 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEAD--NEWVVKLYYSFQDAECLYFVMEYIPGGDMMS---LLIKLGT
|.|.|.||.|||| |.|||||||. .|||| .||......||||||.|||||.||||  |.|||||||||||. .||.||||.||||||.   ||.|...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FPEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLCTG---------------------FRWTHDSKRYQPKGSSGHTRQGSIEP
|.|... |||||.|||||||||||.|||||||||.|| .||||||||||||||                     |.|||.|. ||  ....|..| ....
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQ--NMKEHRPQDFMDN

DTSAWGDQCT-----------CPMKPLEIRRLKEHHRCVAHSLVGTPNYIAPEILRR-VGYTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWP
 .|.  .| .           |. |.|..|. |.. ||.|.|.||||.|.|||.. .  ||.|.|||||.|.||||||||.||| .. | .|. || || 
WNSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWK

EYL-----RIPHHAQLSTAARDLVLRFLS-DPQDRIGRNG--ADEIKHHPFF
...      .|  | ||  | ||  |..  ||. |.|..|  .|||| ||||
QTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase AqueK010.AA AGC 394-699 32 1.1e-180 472.05 In-house 1-395 (395) Show / Hide 
Range on Protein: 394-699
Range on HMM: 1-395/395
Sequence Identity: 32% (137 aa)

FDIVKPIGVGAFGVVSLVRKK------DTRRLYAMKSLRKAD-VVRRN--QVAHVKAE------------RDILAEAD----------NEWVVK-LYYSF
|...|.|| |.|| | |||||      || ..|||| |.|.. .|...  .|.|...|            |.||....          . ..|| |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDAEC--LYFVMEYIP--------GGDMMSLLIKLG-----TFPEHLTLFYIAE-------LVCAIESVHK-MGFIHRD-IKPDNILIEADGHIKLTDFG
|| .   |||||||.|        ||.....|.. |     .|.|  . ||.||       .|.|.|. |. ||.|||| .||.|||. .||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCTG----------------FRWTHDSKRYQPKGSSGHTRQGSIEPDTSAWGDQCTCPMKPLEIRRLKEHH-----------RCVAHSLVG--TPNYIAP
||.                 |.| |..|  | |.        . .  | .         | .. ......            |  .....|  ||.|.||
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS--------NMD--T-N---------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAP

EILRRVGYTQLCDWWS--VGVIMYEMLVGQPPFMAS----------APADTQLKIVN----WPEYLRIPHH--------AQLSTAARDLVLRFLS-DPQD
|||    |.. |||||  .|..|||||.|.||| .            |...  || |    ... ...|..         ..|  |.||. ..|  || .
EIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEK

RIGRN-------GADEIKHHPFF
|.| .       ||.||| ||.|
RLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK010.AA DMPK 394-539 48 9.80000000001e-107 264.72 In-house 1-147 (270) Show / Hide 
Range on Protein: 394-539
Range on HMM: 1-147/270
Sequence Identity: 48% (72 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLG-TFPEH
|.|.| || |.|| | .|| | |.. |||| . |.. . | ..| .. ||||.. .. .|...|.| ||| . ||.|||| ||||. .|. . .  .|| 
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

LTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLC
.. ||.||.| || |.|.||..||||||||.|.   ||||| ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC
Kinase AqueK010.AA RSK 397-699 34 1.5e-101 343.63 In-house 1-278 (278) Show / Hide 
Range on Protein: 397-699
Range on HMM: 1-278/278
Sequence Identity: 34% (113 aa)

VKPIGVGAFGVVSLVRKK---DTRRLYAMKSLRKADVVRRNQ-VAHVKAERDILAEAD-NEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGT---
.|  | |..| |.|.||.   ||...|||| |.|| .|.|.  ..|...||.||..      .|.|.|.||. . || .|||..||..   | | ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEA---DGHIKLTDFGLCTGFRWTHDSKRYQPKGSSGHTRQGSIEPDTSAWGDQCTCPMKPLEI
| |.   ||.||.|.|.|  |. |.||||.||.||| .    .|||||||||.|  |                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

RRLKEHHRCVAHSLVGTPNYIAPEILR----RVGYTQLCDWWSVGVIMYEMLVGQPPFMA---SAPADTQLKIVNWPEYLRIPHHAQLSTAARDLVLRFL
   . .|   ... ..| .|.|||.|.    ..|... ||||| ||.|||||.|.||| .   . ....  .| .    |..|. . ||..|.||. . |
---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKML

S-DPQDRIG--RNGADEIKHHPFF
  ||..|.|  ...|.||| ||.|
HRDPHKRLGCGPQDAEEIKQHPWF
Kinase AqueK010.AA S_TKc 394-699 31 4.7e-101 342.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 394-699
Range on HMM: 1-231/231
Sequence Identity: 31% (101 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPG--GDMMSLLIKLGT---
..|...|| ||||.| ..|.|.| |..|.| ..           |.. |..|| . . ...||||..||| ..||.||||..|  ||..... | |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLCTGFRWTHDSKRYQPKGSSGHTRQGSIEPDTSAWGDQCTCPMKPLEI
   |||  . ||.....||.|  |..|.||||.||.|||.    |||..||||.. .                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

RRLKEHHRCVAHSLVGTPNYIAPEILRRVGYTQ-LCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWPEYLRIPHHAQLSTAARDLVLRFLS-DPQD
           ....|||.|.|||.|   ||.   |||||.|.|.||||.|.|||      .. .|..              |  |.|.. . |  ||..
-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEK

RIGRNGADE----IKHHPFF
|..   | .    || ||.|
RPTA-EALQDEWDIKCHPWF
Kinase AqueK010.AA AktR 394-699 34 1.2e-99 337.41 In-house 1-268 (268) Show / Hide 
Range on Protein: 394-699
Range on HMM: 1-268/268
Sequence Identity: 34% (108 aa)

FDIVKPIGVGAFGVVSLVRKK-DTRRLYAMKSLRKADVVRRNQVAHVKAERDILA-EADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGTFPE
|.. |..| |||| | ||.|| |. ..||||...| . ..|||  |.  ||.|.. ....   |||.|.||. |.|.|.|||.|||.. . | | ..| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HLTLFYIAELVCAIESVHKM-GFIHRDIKPDNILIEADGHIKLTDFGLCTGFRWTHDSKRYQPKGSSGHTRQGSIEPDTSAWGDQCTCPMKPLEIRRLKE
  ..||.|. . |.|  |.    | ||.||.|||.. |||.|.|||||                                            |..   ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------LQF---MM

HHRCVAHSLVGTPNYIAPEILRR-VGYTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWPEYLRIPHHAQLSTAARDLVLR--FLSDPQDRIG-
| . .|.|..||| |.|||.... .|..  .|||..|.  |||..|.||| ..   .  .|| . .  ...| ....| ...||. |  .  .|. |.| 
HYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY

-RNGADEIKHHPFF
 .||..||| ||.|
YCNGWEEIKSHPWF
Kinase AqueK010.AA MAST 394-538 48 1.9e-88 270.25 In-house 1-148 (337) Show / Hide 
Range on Protein: 394-538
Range on HMM: 1-148/337
Sequence Identity: 48% (72 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQD--AECLYFVMEYIPGGDMMSLLIKLG-TFP
|...|.|..||.|.| ||..|.|. ..|||.... |  ..||| .|..||.||....|..|||..||||    . |..||||  |||  |||  .| ..|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGL
|... .||||.| ..|  |..| .|||.||||.|| ..||||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase AqueK010.AA MAST 394-538 51 3.6e-86 277.75 In-house 1-145 (334) Show / Hide 
Range on Protein: 394-538
Range on HMM: 1-145/334
Sequence Identity: 51% (74 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGTFPEHL
|...|||. ||.|.| ||..|.|....||| ..|.|  ..|.| .|..||.|||...|..|||..|||| .. |..||||  |||  |||  .|.|.|..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGL
. .||||.| ..|  |..| .|||.||||.|| ..||||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL
Kinase AqueK010.AA Akt 394-539 49 1.5e-76 244.22 In-house 1-148 (264) Show / Hide 
Range on Protein: 394-539
Range on HMM: 1-148/264
Sequence Identity: 49% (73 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLY-AMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGTFPEH
||..| .| |.|| | ||.|||| ..| |||.|.|   . .|||.|.|.|| ||   ..  .|.|.||||... |||||.|..||.  ..| . ..|.| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

LTLFYIAELVCAIESVHKMGFIHRD-IKPDNILIEADGHIKLTDFGLC
 . ||.||...|||  |... | ||  || |||. .||||.|||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase AqueK010.AA ROCK 394-539 50 4.7e-63 213.53 In-house 1-145 (263) Show / Hide 
Range on Protein: 394-539
Range on HMM: 1-145/263
Sequence Identity: 50% (73 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGTFPEHL
|...| || |||| | |||.| ... |||| | | ....|   |    ||||.| |  ||.|.|.| |||.  || ||.|.||||...|. .    ||  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNY-DVPEKW

TLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLC
. || .|.| |....| |||||||.||||.|..  ||.|| ||| |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC
Kinase AqueK010.AA GEK 394-539 49 2.4e-61 204.54 In-house 1-147 (269) Show / Hide 
Range on Protein: 394-539
Range on HMM: 1-147/269
Sequence Identity: 49% (73 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLG-TFPEH
|.|.| || |||| |. |. |.| ..|||| | | ....|  .|  . |||.| . |. |. .| | ||| . ||.||.|  |||.. || | .   || 
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

LTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLC
.  |||||.| ||.|||.....||||||||.|..  |||.| ||| |
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSC
Kinase AqueK010.AA DMPK 600-699 44 1.6e-58 142.81 In-house 162-270 (270) Show / Hide 
Range on Protein: 600-699
Range on HMM: 162-270/270
Sequence Identity: 44% (48 aa)

VGTPNYIAPEILRRVGYT------QLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNW-PEYLRIPHHAQ--LSTAARDLVLRFLSDPQDRIGRNGA
|||| ||.||.|. ..          ||||||||.|||||.|. || | . ..|  ||.|   . |  | . .  .|. |.||. ..|.|...|.||||.
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

DEIKHHPFF
...| ||||
EDFKCHPFF
Kinase AqueK010.AA Pkinase 394-558 32 4.4e-43 153.4 Pfam 1-176 (293) Show / Hide 
Range on Protein: 394-558
Range on HMM: 1-176/293
Sequence Identity: 32% (58 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVK-AERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGG----DMMSLLI--KL
. |...|| |.||.| . ..|.|....|.| ..| .     ...|.. .|  |... . . .|.||..|.|   .|.|||| .||    | ....   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTF--PEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHI----KLTDFGLCTGFRWTHDSKRYQPKGSSG
|.|  .|.   ||. ......|  |.||.||||.||.||||  .|||    |..||||.  |.. ..|  . . |...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW
Kinase AqueK010.AA MAST 600-699 45 3.1e-41 123.29 In-house 229-337 (337) Show / Hide 
Range on Protein: 600-699
Range on HMM: 229-337/337
Sequence Identity: 45% (50 aa)

VGTPNYIAPEILRRVG-YTQLCDWWSVGVIMYEMLVGQPPFMASAPAD-TQLKIVN------WPEYLRIPHHAQLSTAARDLVLRFLS-DPQDRIGRNGA
.||| |||||.. . | | .  ||||.|.|||| ||| ||| .. |   .  .|.|      |||.  .    ..|  |.||. ..|  .| .|.| |||
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

DEIKHHPFF
|||| ||||
DEIKQHPFF
Kinase AqueK010.AA ROCK 600-699 49 4e-37 123.78 In-house 160-263 (263) Show / Hide 
Range on Protein: 600-699
Range on HMM: 160-263/263
Sequence Identity: 49% (51 aa)

VGTPNYIAPEILRRVG----YTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWPEYLRIPHHAQLSTAARDLVLRFLSDPQDRIGRNGADEIKH
|||| ||.||.|.  |    | . |||||||| .||||||. || | .   |  ||..  . |. |  ...|. |.||. .||.| ..|.|||| |.||.
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ

HPFF
|.||
HKFF
Kinase AqueK010.AA GEK 600-699 42 1.8e-35 116.21 In-house 162-269 (269) Show / Hide 
Range on Protein: 600-699
Range on HMM: 162-269/269
Sequence Identity: 42% (46 aa)

VGTPNYIAPEILRRVG-----YTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWPEYLRIPHHAQ---LSTAARDLVLRFLSDPQDRIGRNGAD
|||| ||.||||. ..     | . |||||.||.||||| |. || |   ..|  ||.|. . . .|.. .   .|  |.||. . .  .. |.||||..
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIKHHPFF
. |.||||
DFKKHPFF
Kinase AqueK010.AA MAST 598-699 41 8.3e-35 109.4 In-house 223-334 (334) Show / Hide 
Range on Protein: 598-699
Range on HMM: 223-334/334
Sequence Identity: 41% (47 aa)

SLVGTPNYIAPEILRRVG-YTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQLKIVNWP-EYLRIPHH------AQLSTAARDLVLRFL-SDPQDRIGRN
...||| |||||.. . | . .  ||||.|.|||| ||| |||  . |  .  .|.|       .|          .|  |.||. ..|  || .|.| |
QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

-GADEIKHHPFF
 ||||.| ||||
NGADEVKQHPFF
Kinase AqueK010.AA Pkinase 596-699 26 5.4e-25 89.45 Pfam 168-293 (293) Show / Hide 
Range on Protein: 596-699
Range on HMM: 168-293/293
Sequence Identity: 26% (34 aa)

AHSLVGTPNYIAPEILR-RVGYTQLCDWWSVGVIMYEMLVGQPPFMAS----APADTQLKIVNWPEYLRIPHHAQLS--------------------TAA
.....|||.|.|||..| . .|.. .|.||.|.|.|||| |.|||  .      .| . .|..  .     .  ...                     ..
MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC

RDLVLRFLS-DPQDRIGRNGADEIKHHPFF
.|.. . |  ||..|..   |..|..||.|
KDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase AqueK010.AA Akt 595-639 50 3.8e-24 74.02 In-house 158-203 (264) Show / Hide 
Range on Protein: 595-639
Range on HMM: 158-203/264
Sequence Identity: 50% (23 aa)

VAHSLVGTPNYIAPEILRRVGYTQLCDWWS-VGVIMYEMLVGQPPF
.. .. ||| |.|||||  .|.|. .|||. .|..||||. |.|||
KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF
Kinase AqueK010.AA Akt 658-699 37 3.7e-10 28.6 In-house 220-264 (264) Show / Hide 
Range on Protein: 658-699
Range on HMM: 220-264/264
Sequence Identity: 37% (17 aa)

LRIPHHAQLSTAARDLVLRFLS-DPQDRIG--RNGADEIKHHPFF
...|   ..| ...||. . |. ||  | |   |.|.||| ||.|
VKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase AqueK010.AA TyrKc 394-693 20 6.9e-10 -62.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 394-693
Range on HMM: 1-280/280
Sequence Identity: 20% (69 aa)

FDIVKPIGVGAFGVVSLVRKKDTRRLYAMKSLRKADVVRRNQVAHVKAERDILAEA--DNEWVVKLYYSFQDA-------ECLYFVMEYIPGGDMMSLLI
    | .| ||||.| . . |   .  | |.|..        ..    |  |. .   ... .|.||    .        | |. |||| |.||  . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KLGT-FPEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLCTGFRWTHDSKRYQPKG-SSGHTRQGSIEPDTSAWGDQCTC----
| .  ..    | .     |  |  |....||||.   |.|. .....| .||||.          |.   . ..|            . .|  .     
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS----------RDIYDDDQQG------------ESKDYYRKKEHK

PMK-PLEIRRLKEHHRCVAHSLVGTPNYIAPEILRRVGYTQLCDWWSVGVIMYEML-VGQPPFMAS----APADTQLKIVNWPEYLRIPHHAQ------L
  | .| ||                    ||| ..   .|   | || || |.|..  ||.|         ...  .. |   .....|...        
GGKTMLPIR------------------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCC

STAARDLVLRFLSD-PQDR-----IGRNGADEI
...  .. ..     | ||     |     ...
PDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase AqueK010.AA Pkinase_Tyr 394-539 26 1.5e-07 26.19 Pfam 1-158 (270) Show / Hide 
Range on Protein: 394-539
Range on HMM: 1-158/270
Sequence Identity: 26% (42 aa)

FDIVKPIGVGAFGVVSLVRKK----DTRRLYAMKSLRKADVVRRN--QVAHVKAERDILAEA-DNEWVVKLYYSFQ-DAEC--LYFVMEYIPGGDMMSLL
  . | .| ||||.| . . |    .|.   | |.| | .   ..  . .  . |  |. .  ... .|.||     . |   .| |||| |.||. . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

IK----LGTFPEHLTLFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLC
 |     . .. .  | . ..  .. |  . ...||||.   |.|.. ....| .||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
S_TK_X AqueK010.AA S_TK_X 701-766 26 3e-06 27.83 SMART 1-79 (79) Show / Hide 
Range on Protein: 701-766
Range on HMM: 1-79/79
Sequence Identity: 26% (22 aa)

SRIDWDVGIRN----YVAPYKPKIM----YEGDTSNFDPVPQSQVQKMYKQATPT-EVMPQDHPEHA---------FYEFTFIR
. |||| ...|    . .|.||||      ..|||||||   ... .    .||. ... . . . .         | .||...
RGIDWD-KLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF