Gene AqueK009 (A.queenslandica)

AqueK009

Species: A.queenslandica
Alias: AqueK009
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
AqueK009.AA Protein None 1368 None Fasta, JSON
AqueK009.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of AqueK009.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF1908 AqueK009.AA DUF1908 181-279 34 6e-06 22.05 Pfam 1-96 (369) Show / Hide 
Range on Protein: 181-279
Range on HMM: 1-96/369
Sequence Identity: 34% (38 aa)

PCGSPR-TWSPSITNFERF----SHGRRSEMRNDMRRWSLVSQ-SSGYTTYTSATDSPASLSSY-PSQEHI----HAPQDHTNNQLPTTPTPEDFAKLRK
|  |||   ..|  ||  |    ... ... | | ||||. |  |||| | .       ..||   |||      |        |||  || .| . | |
PIDSPRNFSTSSMMNFP-FVPIRRITNCRD-RADGRRWSVASLPSSGYGTNPPS----SNVSSQCSSQERLNQLPH--------QLPFQPTQDDLHFLSK

HFRSDSSGSS
||..  |  |
HFCCTESNPS
DUF1908 AqueK009.AA DUF1908 290-434 33 2.4e-28 103.14 Pfam 181-330 (369) Show / Hide 
Range on Protein: 290-434
Range on HMM: 181-330/369
Sequence Identity: 33% (51 aa)

ATHRLRARSL-SPERSPRE--SLLDLDDTHAIFREKYPRAKLEMENQLVTFMNEFS---ETNRQFSDSNVNFARHQILEFARELLFKSQNDLLSKEVFIQ
. ||.| ||| ||.||.    .   .  .  ...| .|.|   || .|. |...|.   ..  . .|  | | .||..| ||  | ||.. |     |. 
PHHRPRSRSLSSPSRSCITFDNEIVMMNH--VYKERFPKATQQMEERLQHFIHHFKNIPCDSLRLADPVVRFIHHQVVEMARDCLHKSHAKLITSRYFYE

FSENVLQAVTNVRERN-GAESPELNQLVRKLLTVISRVARLVEIIEFDPNAF
 .|.  .   . .||   .| |.......||| .||| ||| |  ||||  |
MQEKLERLLHEAHERSESEEVPFITHVIKKLLIIISRPARLLECLEFDPEEF
Kinase AqueK009.AA MAST 511-787 44 2.4e-169 522.06 In-house 1-337 (337) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-337/337
Sequence Identity: 44% (152 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQT--RQHLYMVMEYVEGGDVAALLKGVG-YLT
|. ||.||.|||||||||.|| |. |||||. |.  .| |.||..|| ||.|||. .||||| . ..|||  ...|.|||||.||||.| ||. .|  . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

LELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIED---------------AWAKDYQFV-------------
 ..| ||. ||||.|||.||.||.||||||||.||.| ||||||||||||.|... .  ..|.                  |.||               
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------DQEVYGTPDYIAPEVILGMP-YGFPVDWWSMGVILYEMMMGVTPFVSSTIQD-LFEEITNENLHISFPEE------
                        .. ..||||||||||||| . || ||||||||.|.||   |..||. .| .  .|. |.| . .|..|||      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

DEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
|.....||||...|   .|  |||  |. |.  .|.||||
DCMSPEAQDLIKKLLQPNPKKRLG--AN-GADEIKQHPFF
Kinase AqueK009.AA AGC 511-787 29 3.7e-159 415.12 In-house 1-395 (395) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

FDVIKIISNGAYGAVYLVRHK------QTRMRFAMKKVNKKR-MIMKK--QVQSVFNE------------RDILTFSE----------NPFVVG-LWCTF
|...|.|. |..| |||||.|      .|   .|||...||. ...||  .|. . .|            |.||.             .||.|  |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTRQH--LYMVMEYVE---------GG-DVAALLK---GVGYLTLELATMYFSE-------TVLALEYIHS-HGIIHRD-LKPDNLLITSEGHIKLTDFG
|. .|  ||.||||..         || .    |.   . |... | |  |..|       .||||||.|| .|||||| |||.|.|....|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKIGLTNYAA-------------------------HVIEDAWAKDYQ------------FVDQEVYG--TPDYIAPEVILGMPYGFPVDWWS--MGVIL
|.|.| ...                           . .. . ... .            .  .   |  ||.|.|||..    ||...||||  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YEMMMGVTPFVSSTIQ----------DLFEEIT------NENLHISFP------EEDEIPDDAQDLVRQLMCFDPMYRLGSTARE----GVSGVKSHPFF
|||. | .|| . . |          ..|. |       |..... ||      |.... ..|.||...|.| ||  |||.  .     |.. .|.||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK009.AA MAST 511-787 44 5.9e-159 516.32 In-house 1-334 (334) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-334/334
Sequence Identity: 44% (150 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLEL
|. ||.||.||||.||||.|| |. |||||...|  || |..|..|. ||.||....||||| . ..|||...|.|||||.||||.| ||. .||.  ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIED----------------AWAKDYQFV---------------
| ||..||||.|||.|||||.||||||||.||.|.||||||||||||.|... .  ..|.                   .. ||.               
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------------DQEVYGTPDYIAPEVILGMP-YGFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLH-ISFPEE------DEIP
                    .. ..||||||||||||| . .| ||||||||.|.|| . |..||. .| . .|. |.|.|   |..||.      ....
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

DDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
 .||||...|   ||  |||  |. |.  ||.||||
PEAQDLIEKLLQPDPRKRLG--ANNGADEVKQHPFF
Kinase AqueK009.AA S_TKc 511-787 34 9e-93 315.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-231/231
Sequence Identity: 34% (99 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEG--GDVAALLKGVGY---
......|  ||.| ||..||| |  ..|.|...          ... .|..||     |..| |  .||. .||||||||..|  ||.  ..|  |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVILGMPYGF
   ..   |  |. ....||||.||||||||||||.|.|...  |||..||||...                        . |||.|.||||.   .||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL---GYGK

-PVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVS---GVKSHPFF
 ..|||| |.|||||. | .||   ..| .|. |               ...| |..|.....||  |.  || |       .|.||.|
CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRP--TA-EALQDEWDIKCHPWF
Kinase AqueK009.AA AktR 511-787 36 4.3e-90 305.62 In-house 1-268 (268) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-268/268
Sequence Identity: 36% (105 aa)

FDVIKIISNGAYGAVYLVRHK-QTRMRFAMKKVNKKRMIMKKQVQSVFNERDILT-FSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTL
|.|.|.. .||.| ||||..| ..   .||| . || .| ..| . . .||.|.   . .|| | |  .|||. .|. .|||..||.    ||  . .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ELATMYFSETVLALEYIHSH-GIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQE------VYGTPDYIAPEVILG-MPY
| |  ||.. .||||| |.|  || |||||.|.|. ..||.|.|||||||                   ||.. .      ..||| |.|||.|.   ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGH

GFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVR-QLMCFDPMYRLGSTAREGVSGVKSHPFF
...||||. |. .|||..| .|| ..  ...|. | ...  ..||.  .. . ..||.  .|.| .|  |||. ...| . .||||.|
NKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY-YCNGWEEIKSHPWF
Kinase AqueK009.AA RSK-Unclassified 511-787 35 6.1e-88 276.27 In-house 1-283 (283) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-283/283
Sequence Identity: 35% (102 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLK--GVGYLTL
| ... |  |  | ||||| |.| . .|||  .|..|| .. .. |  |..|.  .. ||.| |   |||.  ||..|||  |||    |       .. 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

ELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIG-------LTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVILGMPYG
... .| ||...|||| |  ..| ||||||| .   |||..||||.||. .       .   |   . |    |  |  .   || .|.|||.| .   .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

FPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREG-VSGVKSHPFF
  |||| .|...|||..|..|.       .|. |  |  |..||.. .|  ...||.. |.   |  |||.    |    .| ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNI--EKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGC--KMGDADDIKRHPFF
Kinase AqueK009.AA RSK 514-787 33 4.8e-87 295.48 In-house 1-278 (278) Show / Hide 
Range on Protein: 514-787
Range on HMM: 1-278/278
Sequence Identity: 33% (98 aa)

IKIISNGAYGAVYLVRHK---QTRMRFAMKKVNKKRMIMKKQ--VQSVFNERDILTFSE-NPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGY--
.|    |.||.|.|.| .   .|.. .|| || ||..|...|  .  .. ||.||  ..  ||.| |  .||| ..||..|||..||.    |.  ..  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAM-KVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITS---EGHIKLTDFGLSKIGLTNYAAHVIE-DAWAKDYQFVDQEVYGTPDYIAPEVIL---G
 .. . | .|..| |||.|..|..|||||||||.| | ..   ||||||||||..|..       ...   |..          .| .|.|||..    .
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------RCDHNQWTMT-------FCYTIEYMAPEMLKRANQ

MP-YGFPVDWWSMGVILYEMMMGVTPFVS---STIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
   ..  .|||| ||..||| .| .|| .   .. ..... | . ..  ..|. ... ..|.||.|.... ||  |||.  ..... .|.||.|
QGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGC-GPQDAEEIKQHPWF
Kinase AqueK009.AA Ciliate-E2 511-787 23 3.2e-81 276.13 In-house 1-365 (365) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-365/365
Sequence Identity: 23% (92 aa)

FDVIKIISNGAYGAVYLVRHKQTR-----------------------MRFAMKKVNKKRMIMKKQVQSVF----------NERDILTFSENPFVVGLWCT
...||.| .|..| ||........                       . .||| ..|.  ...||.....          ||. || .  .|... .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TRQHLYMVMEYVEGGDVAALLK-------------------GVGYLTLELAT-------MYFSETVLALEYIHSHG-IIHRDLKPDNLLITSEGHI
||  .....|.||||..|||   ..|                    ..|.. ...        .|. . .|||||.|| . |||||.||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQE-------------------VYGTPDYIAPEVILGMP---------YGFPVDWWSMGVILYEMMMGV
|..||||||.  ...  . .    .| |.|  ..                   ..||| | |||.. | .         |.. .|.||.|||||||..| 
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPFVSSTIQDLFEEITNENLHISFPE--------------EDEIPDDAQDLVRQ----LMCFDPMYRLGSTAREGVSGVKSHPFF
.||        ...| . .. ...||               ........|| ..    ... ||  |..     | . .. ||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-----GWEQILNHPWF
Kinase AqueK009.AA Pkinase 511-787 30 2.6e-79 274.57 Pfam 1-293 (293) Show / Hide 
Range on Protein: 511-787
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVF-NERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGG----DVAALLK--GV
. ....|  |..| ||. .|| |. ..|.|...|..  ..|... .  .|  |.     |..| |...|....|.||||||.|||    | .....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYL--TLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHI----KLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVIL-
| .  . . . .|. ... .|||.||.|||||||||.|.|| ..|||    |..||||.|                  ..  .  . |||.|.|||||. 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------Y-NNS-MTTFC-GTPWYMAPEVIRG

GMPYGFPVDWWSMGVILYEMMMGVTPFVSS------TIQDLFEEITNENLHISFPEEDEIP-----------------DDAQDLVRQLMCFDPMYRLGST
| .|| .||.||.|.|||||. | .|| ..      . . ....|    || ..|....|.                 ....|... . |.||  |..  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--

AREGVSGVKSHPFF
       .. ||.|
----AEQILQHPWF
Kinase AqueK009.AA NDR 511-663 48 4.4e-77 237.13 In-house 1-158 (350) Show / Hide 
Range on Protein: 511-663
Range on HMM: 1-158/350
Sequence Identity: 48% (76 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSE--NPFVVGLWCTFQTRQHLYMVMEYVEGGDVAA---LLKGVGY
|..||||. ||.| |.|||.| |.  .|||...|. |..| || .| .||||.. .   ||.|| | ..||  |.|| ||||. |||      ||.  ..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNY
.| ..|  | .|.|.|.|..|. |.||||.||||.|| . ||||||||||.. |.. .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRR
Kinase AqueK009.AA Akt 511-662 41 1.6e-57 182.45 In-house 1-155 (264) Show / Hide 
Range on Protein: 511-662
Range on HMM: 1-155/264
Sequence Identity: 41% (64 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRF-AMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLE
||..|..  |..| |.||. |.|   . |||   |.. |.|.||. .. || ||    .||.|.|   ||| ..||.||.|. ||.   .|.  .. . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

LATMYFSETVLALEYIHSHGIIHRD-LKPDNLLITSEGHIKLTDFGLSKIG-LTN
 |  | .| .||.|. ||..|| || ||| |.|. ..|||.||||||.| . ...
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKD
Kinase AqueK009.AA PKA 511-657 45 5.2e-56 192.4 In-house 1-149 (263) Show / Hide 
Range on Protein: 511-657
Range on HMM: 1-149/263
Sequence Identity: 45% (68 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVG-LWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLE
|. |. . .| .| |.|.|||..   .|||  .| . .  |||. | ||. ||.  ..||.|  .. |||....||||||||.||..   |  .| ..  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

LATMYFS-ETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSK
 |  |   . ||||||.||. ||.||||| |.|| ..||||.|||| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK
Kinase AqueK009.AA NDR 685-787 45 2.1e-42 128.18 In-house 243-350 (350) Show / Hide 
Range on Protein: 685-787
Range on HMM: 243-350/350
Sequence Identity: 45% (50 aa)

GTPDYIAPEVILG-MPYGFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITN--ENL---HISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGV
|||||.||||...   |.. .|||| |.|.||| .|..||.|.|.|. .. | |  . .    ..||.| .. ..|.|| |.|.| ||. ||||   .||
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG-KGV

SGVKSHPFF
  .||||||
DEIKSHPFF
Kinase AqueK009.AA Akt 685-787 37 1.7e-32 101.15 In-house 164-264 (264) Show / Hide 
Range on Protein: 685-787
Range on HMM: 164-264/264
Sequence Identity: 37% (39 aa)

GTPDYIAPEVILGMPYGFPVDWWS-MGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKS
||| |.|||...|  .. .||||.  |...|||| |  || .  .. .|. | |...   ||. | | ....||...|   ||  |||..  ...  .|.
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPV--KFPDKDWISPECKDLISGLLNKDPKKRLGGGP-NDAQEIKR

HPFF
||.|
HPWF
Kinase AqueK009.AA PKA 685-787 35 2.7e-28 100.31 In-house 160-263 (263) Show / Hide 
Range on Protein: 685-787
Range on HMM: 160-263/263
Sequence Identity: 35% (39 aa)

GTPDYIAPEVILGM-PYGFPVDWWSMGVILYEMMMGVTPFVSS--TIQDLFEEITNENLHISFPEEDEIPDDA---QDLVRQLMCFDPMYRLGSTAREGV
|||.|.|||.|..  ..| .||||. |.. |||. |..||  .  .  ...| |   |  | ||...    ||    ||...|.  |. .|.| . ..||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKIC--NGKIKFPRHFD--SDANYFKDLIKKLLQVDLTKRYG-NMKNGV

SGVKSHPFF
  .| |..|
NDIKNHKWF
Kinase AqueK009.AA TyrKc 511-781 21 1e-12 -17.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 511-781
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFS--ENPFVVGL--WCTFQTR-----QHLYMVMEYVEGGDVAALLK
   .|.. .||.| ||. . |   .  | |....        ..   .|  |..    ..| .| |   || | |     . |..||||...||    |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

GVGY-LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTN-YAAHVIEDAWAKDYQFVDQEVYGT-----PD------
  .  |...    .        ||.||...|||||   | |.......| .|||||. .     .              . ...| .      .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------ESKDYYRKKEHKGGKTMLPIR

YIAPEVILGMPYGFPVDWWSMGVILYEMM-MGVTPFVS-----STIQDLFEEITNENLHISFPEEDE------IPDDAQDLVRQLMCFDPMYRLGSTARE
  |||.|    . .  | || || ..|..  | .|         . |...| . . .     |..|.       ||.  ..   ..| .       | .|
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR-MPQPPNDYPMSFVCCPDEMYQIM--KQCWHEDPEDRPTFSE

GVSGV
 ..  
IHECF
Kinase AqueK009.AA Pkinase_Tyr 581-657 31 2.8e-09 32.04 Pfam 77-159 (270) Show / Hide 
Range on Protein: 581-657
Range on HMM: 77-159/270
Sequence Identity: 31% (26 aa)

RQH--LYMVMEYVEGGDVAALLKG----VGYLTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSK
...  .|.||||...||    |.      . ||..    .  .   ..|| .|...|||||   | |.|.....| .||||..
GEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase AqueK009.AA S_TK_X 788-848 19 1e-07 32.86 SMART 1-79 (79) Show / Hide 
Range on Protein: 788-848
Range on HMM: 1-79/79
Sequence Identity: 19% (17 aa)

SEIDWNLLLR----TKAEFIPQLR----GDDDTSYFD---TRENRYPQNEFASDEEPDGDT------DQP----------FDNFSSTA
..|||. |..    ... |.|...    .. |||.||   |.|            . . |.      .|.          | .|.  .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AqueK009.AA Pkinase_C 805-850 23 0.000505 17.5 Pfam 1-46 (46) Show / Hide 
Range on Protein: 805-850
Range on HMM: 1-46/46
Sequence Identity: 23% (11 aa)

QLRGDDDTSYFDTRENRYPQNE-FASDEEPDGDTDQPFDNFSSTAPR
|.....|||.||. . . | .. . ...      . || .|. ..| 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
PDZ AqueK009.AA PDZ 1034-1115 20 8.9e-09 36.41 SMART 1-80 (80) Show / Hide 
Range on Protein: 1034-1115
Range on HMM: 1-80/80
Sequence Identity: 20% (19 aa)

KGYGMTLKPIRVYIGDSNNYRIHHIVQSVDKDGPAYKAG------LRPNMLVTHING-EAVTGLQHVQVVSLMFKNSK----KDASAKAKDSK
.|.| ...              .... || ..|||.|||      |||.  .. .|| . |... | |.| .. . ..    .  . . .  .
GGLGFSIVG-------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG