Gene CC1G_13961 (C.cinerea)

CC1G_13961

Species: C.cinerea
Alias: CC1G_13961
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-ccin

Sequence

Name Sequence Type Origin Length Description Download
CC1G_13961.AA Protein None 1208 None Fasta, JSON
CC1G_13961.NA RNA None 3627 None Fasta, JSON
CC1G_13961.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of CC1G_13961.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CC1G_13961.AA TKL 228-483 20 2.2e-56 193.62 In-house 4-364 (364) Show / Hide 
Range on Protein: 228-483
Range on HMM: 4-364/364
Sequence Identity: 20% (77 aa)

GTFNDIYKGRWLNE---------KMVALRLPRSLPNTPRLQ-------------------------RRFEEEVKIWRKLNHPNVLTLYGITKIGQY----
|.|  .|||.| ..         | ||    .|  .  .                            ..|||... ..|.|||.. ..|. . ...    
GGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVC

---------VYLVSPWMDNGT-AINYIQKNPNVDRLGLLEQITSGLEYLHSQN--------IVHGDIRGANILISENGV--------------ALLADFG
          ..|  ....|.   ...       |. .  .| .|..||||.|        |.| |.  .|||. ||.               . ..|||
MHPVGPWGQLCIVMEYCPGGSLLHYLH----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFG

LSKFLGDIGT---------------VAQAMTVTVASNPRWSAPEILRNAGSKSTVS---------PYSKKSDIWSIGMTFLELLTGECPYAYESIDVAV-
||.|.   |                .   .| |.  .||| |||.||...  .  .         .||.|.|..| |. . |.||.. ||. .  .  . 
LSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIF

--------LRLIDNNETPKRP-----REGKYHHNITDHLW----KLMTRCWKMKPDSRPDIAYVRGKL
           .|... | .|     .. |      .. .    |||..||...|..||    .  .|
QDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc CC1G_13961.AA S_TKc 219-484 22 2.6e-39 137.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 219-484
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

KESEHVAFFGTFNDIYKGRWLN-EKMVALRLPRSLPNTPRLQRRFEEEVKIWRKLNHPNVLTLYGITKIGQYVYLVSPWMDN--GTAINYIQKN------
 |   .   |.|   ||.|. .  . ||.   .         .... |..| .| .|||. .||..    ...|.|   .|.  |.   ||.|.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

---PNVDRLGLLEQITSGLEYLHSQNIVHGDIRGANILISENGVALLADFGLSKFLGDIGTVAQAMTVTVASNPRWSAPEILRNAGSKSTVSPYSK-KSD
   |  .   .. || ..|||.||..|.| |.  .|||..|  .  ..||||...|            |.   | . |||.|          .|.| |.|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----------GYGKCKCD

IWSIGMTFLELLTGECPYAYESIDVAVLRLIDNNETPKRPREGKYHHNITDHLWKLMTRCWKMKPDSRPDIAYVRG--------KLI
.||.| .. |.|.|. |.     . .....|                  .. .. .. .|... |. || .  .            .
WWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CC1G_13961.AA STE 259-475 22 3.5e-39 136.03 In-house 72-347 (359) Show / Hide 
Range on Protein: 259-475
Range on HMM: 72-347/359
Sequence Identity: 22% (65 aa)

QRRFEEEVKIWRKLN--HPNVLTLYGITKIG-------QYVYLVSPWMDNGTAINYIQKNPNVDRLG-----------------LLEQITSG-LEYLHSQ
. ....|.|| .|.|  |||. . ||    .       ......  .||.|..   |...  . .                    . ||  | |.||||.
MQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSH

NIVHGDIRGANILISENGVALLADFGLSKFLGDIGT-----------VAQA-MTVTVASNPRWSAPEILRNAGSKSTVSPYSKKSDIWSIGMTFLELLTG
.|.| || .||||.     . |.|||... | |...             .. .. |..  | | |||.... |.. ....|. |.||||.| | .|..||
HIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATG

ECPYAYESIDVAVLRLIDN--------------NETPKRPREGK-------------YHHNITDHLWKLMTRCWKMKPDSRPD
. |.. ..   | .. ..|              .. |. | . .             |.|. ....   . .| .. |. ||.
KPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase CC1G_13961.AA Pkinase 265-483 22 4.3e-39 139.32 Pfam 50-293 (293) Show / Hide 
Range on Protein: 265-483
Range on HMM: 50-293/293
Sequence Identity: 22% (59 aa)

EVKIWRKLNHPNVLTLYGITKIGQYVYLVSPWMDNG----TAINYIQ--KNPNV-----DRLGLLEQITSGLEYLHSQNIVHGDIRGANILISENGVA--
|..| ..|||||...||..   ....|.| .....|        ||.  .. ..     .    . || .||||.||..|.| |.  .||||..||.   
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA

--LLADFGLSKFLGDIGTVAQAMTVTVASNPRWSAPEILRNAGSKSTVSPYSKKSDIWSIGMTFLELLTGECPYAYES----IDVAVLRLIDNNETPKRP
   ..||||.|..    .  .  . |..  |.. |||..|      . ..|..|.|.||.| .. |.|.|. |.  ..      .  . .|...  |. .
CVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR------GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLH

REGKYHHNIT-----------------DHLWKLMTRCWKMKPDSRPDIAYVRGK--L
..  . ..|                  . . .....|....| .|| .. .     .
FDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CC1G_13961.AA TK 230-483 15 1.6e-38 126.27 In-house 15-486 (486) Show / Hide 
Range on Protein: 230-483
Range on HMM: 15-486/486
Sequence Identity: 15% (74 aa)

FNDIYKGRWLNEK--------------------------MVALRLPRSL-PNTPRLQRR--------------FEEEVKIWR--KLNHPNVLTLYGITKI
| ..|||.| ...                           ||    ..  ..... ..               . || |. .  ...|||.. |||.   
FGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQ

G------------QYVYLVSPWMDNGT----AINYIQKNP------------------------------------------------------------
|            . ...|  .|..|       .| .|..                                                            
GEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTT

-------------------NVDRLGLLEQITSGLEYLHSQ------NIVHGDIRGANILISENGV-----------ALLADFG--------LSKFLGD--
                     ..|    || .|.|||||.      |.||.|.   |.|..||.|           . .||||        |.. ...  
KDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDD

IGTVAQAMTVTV--------------------ASNPRWSAPEILRNAGSKST--VSPYSKKSDIWSIGMTFLELLT-G-ECPYAYESI--------DVAV
  ....  ....                        || ||| |.     .      .. |||.|| | .  |..| | | .| . |         .  |
DYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEV

LRLIDN---------------NETPKRPREGK---YHHNITD-----HLWKL-MTRCWKMKPDSRPDIAYVRGKL
.... .               .. |. |       |..   .      .. . |..||. .|. ||. . .. .|
MEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CC1G_13961.AA MLK 228-483 26 1.2e-36 124.73 In-house 10-291 (291) Show / Hide 
Range on Protein: 228-483
Range on HMM: 10-291/291
Sequence Identity: 26% (79 aa)

GTFNDIYKGRWLNEK----MVALRLPRSLP----NTPRLQRRFEEEVKIWRKLNHPN----VLTLYGI-TKIGQYVYLVSPWMDNGTAINYI---QKNPN
|.| . .|||| |.      ||..  |. .     |   |. ||.|... |.|.|||    .  .||. .. .. ...|. ....|   |..   .....
GSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWM

-----------VDRLGLLE---QITSGLEYLHSQN---IVHGDIRGANILISE------NGVALLADFGLSKFLGDIGTVAQAMTVTV-ASNPRWSAPEI
           .|   ..    |. .|..||||.    |.| |.   ||||.|      .|..  .|||.|... ...|     . .  | ...| |||.
DANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCT-----NMMSNAGTYAWMAPEV

L-RNAGSKSTVSPYSKKSDIWSIGMTFLELLTGECPYAYESID-VAVLRLIDNNE-TPKRPREGKYHHNITDHLWKLMTRCWKMKPDSRPDIAYVRGKL
. .     .  ..||.|.|.||.|. . |.||.| ||. . .|  |..  . .|. .|  | .      . .|. |||..||...| .||. ...  .|
IQQ-----FRCEKYSEKCDVWSWGVVLWEMLTREVPYK-QHYDPMAIAWWVAYNGLRPPIPST------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase CC1G_13961.AA UTK 227-483 22 2.8e-34 114.66 In-house 9-296 (296) Show / Hide 
Range on Protein: 227-483
Range on HMM: 9-296/296
Sequence Identity: 22% (68 aa)

FGTFNDIYKGRWLNEK------MVALRLPRSLPNTPRLQR---RFEEEVK---IWRKLN-HPNVLTLYGITKIGQYVYLVSPWMDNGTAINYIQKNPN--
.| | ...|.|. ...       ||.   ..  .... ..   .| || .   .  ... ||||| |.|.   ..  ..|.  | ||  ..| ....   
QGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTP

------VD---RLGLLEQITSGLEYLHSQNIVHGDIRGANILISENG-------VALLADFG---LSKFLG-------DIGTVAQAMTVTVASNPRWSAP
      ..   ||.   .| .|..||||...||.|.   |.|. ...       |. .||||   .|. ..       . ..    ...  .   || ||
PACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAP

EILRNAGSKSTVSPYSKKSDIWSIGMTFLELLT-GECPYAYESIDVAVLRLIDNNETPKRPREGKYHHNI----TDHLWKLMTRCWKMKPDSRPDIAYVR
|.| ..        .. |||.|| | .  |..| |  ||.  | . ..... . .          |...      . ...||.|||.. |. |||.  ..
EALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGR---------YRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

GKL
 ..
QQM
Kinase CC1G_13961.AA Pkinase_Tyr 255-483 27 6e-34 115.59 Pfam 41-270 (270) Show / Hide 
Range on Protein: 255-483
Range on HMM: 41-270/270
Sequence Identity: 27% (68 aa)

TPRL--QRRFEEEVKIWRKL-NHPNVLTLYGITK-IGQY--VYLVSPWMDNGTAINYIQKN-------PNVDRLGLLEQITSGLEYLHSQNIVHGDIRGA
...   .. | .|.|| ..| .|||.. |||.    |.   .|.| . | .|   .| .|.       .  | |.   || .|.|||.|.|..| |..  
MHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAAR

NILISENGVALLADFGLSKFLGDIGTVA-QAMTVTVASNPRWSAPEILRNAGSKSTVSPYSKKSDIWSIGMTFLELLT-GECP-YAYESIDVAVLRLI-D
|.|..||.|.  .||||.. .        .. . .     .| ||| ...         .. |||.|| | .  |..| || | |.    .  |...| .
NCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGK-LPIKWMAPECINYGK-------FTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYE

NNETPKRPREGKYHHNITDHLWKLMTRCWKMKPDSRPDIAYVRGKL
...  ..|      .| .| . .||..||. .|. ||  .... .|
DGYRMPCP------ENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase CC1G_13961.AA Ciliate-E2 219-428 21 8.4e-33 109.91 In-house 1-300 (365) Show / Hide 
Range on Protein: 219-428
Range on HMM: 1-300/365
Sequence Identity: 21% (67 aa)

KESEHVAFFGTFNDIYKG-RWLNEKMVALRLPRSLP-------------------NTPRLQRRFEEEVKIWR----------------KLNHPNVLTLYG
 .   .  .|.| ..||. .|.. |..|... .                      . ..  . .. | .|.|                .|||||.. .| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

ITK--IGQYVYLVSPWMDNGTAINYIQKNPN--------------VDRLGLLEQITS---------------GLEYLHSQN-IVHGDIRGANILISENGV
  .    ...|||    . |.   ||..|.                 .. . .||..               .||||||.| |.| ||   |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ALLADFGLSKFLGDIGT---------------------------VAQAMTVTVASNPRWSAPEILRNAGSK--STVSPYSKKSDIWSIGMTFLELLTGEC
  ..||||||.. |                              . | |. |.. .|   |||||.. .    ..  .|..|.||||.|... |.|.|. 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYAYESI
|. .. |
PF-QQQI
Kinase CC1G_13961.AA Ciliate-E2-Unclassified 270-794 9 2.3e-31 106.09 In-house 76-323 (352) Show / Hide 
Range on Protein: 270-794
Range on HMM: 76-323/352
Sequence Identity: 9% (54 aa)

RKLNHPNVLTLYGITKIGQYVYLVSPWMDNGTAINYIQKNPN--------------------VDRL-----GLLEQITSGLEYLHSQN-IVHGDIRGANI
. ..||... .. . .  |..|.|   ...|. ..||.|...                       .      .. || .||||||..| |.| ||   ||
LNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENI

LISENG---VALLADFGLSKFLGD----IGTVA--------QAMTVTVASNPRWS----APEILRNAGSKSTVSPYSKKSDIWSIGMTFLELLTGECPYA
|...||      ..|||.||....      |          | |. |.. .|.      |||.|.. .   . .   .|.|||| |. . |.|.|..|. 
LFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPFY

YESIDV---------------AVLRLIDNNETPKRP---REGKYHHNITDHLWKLMTRCWKMKPDSRPDIAYVRGKLIRIREEAYSPDAAQQSTQAASLF
... .                 ... | .... ...   ..                                                           
DNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ-----------------------------------------------------------

SPSFISTRVGTSRHQRVATVDNYSVVSSNSGNDRNRPQDLPTLDVPQNGNLSHRPPSLRPSTSGSSNSGNSSNSGGPSKHRPNAPRFSPIDEDTALSPTS
                                                                                                    
----------------------------------------------------------------------------------------------------

YSSSPPSISPLSAFSAQALTGRSPAKRQGTGFSGFSGTNANKHPAPPSPSASISSSIDGNYRREFSSAPRLPPVSPPSSAGLLSELGWSKSSSSNSASSS
                                                                                                    
----------------------------------------------------------------------------------------------------

RTVTQGTAYTRMDLRQSNGTRSNGNSGQNILYENNEETTPHRATPSSSPPNANHPCTAPLPMKGKARSIDTVGVKSIFSTNSSVQPSD
                                                                             .. ..| .  |
-----------------------------------------------------------------------------IPKHWSPEAKD
Kinase CC1G_13961.AA TKL-Unique 262-423 26 7.3e-29 99.0 In-house 42-234 (290) Show / Hide 
Range on Protein: 262-423
Range on HMM: 42-234/290
Sequence Identity: 26% (52 aa)

FEEEVKIWRKLN-HPNVLTLYGITK----IGQYVYLVSPWMDNGTAINYIQ-------------KNPNVDRLGLLEQITSGLEYLHSQN--IVHGDIRGA
||.||... ||. |||.....|...       . ..|.  .. |.  ....             |...  |. . ..| .|..|||. .  | |.|..  
FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSS

NILISEN-----GVALLADFGLSKFLGDIGTVAQAMT-----VTVASNPRWSAPEILRNAGSKSTVSPYSKKSDIWSIGMTFLELLTGEC------PY
|.|...|       . ..|||||||.  | .    .       |. ...||.|||.||.       . ||.|||..| |.   |..|..       ||
NFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF-----CQYSEKSDVYSFGIVLWEIATRKITKTYKKPY
Kinase CC1G_13961.AA CAMK 255-410 18 8.5e-29 89.34 In-house 71-321 (425) Show / Hide 
Range on Protein: 255-410
Range on HMM: 71-321/425
Sequence Identity: 18% (47 aa)

TPRLQRRFEEEVKIWRK-------LNHPNVLTLYGITK------------IGQY--------VYLVS---PWMDNG----TAINYIQKNPNV--------
.|. ..... |..| .|       |.|||.. || .                ..        .|.|      ...|       .||.....         
RPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFD

----DRL------GLLEQITSGLEYLHSQNIVHGDIRGANILISEN-----------------GVALLADFGLSKFLGDIGTVA----------------
     |.       .  || |...|.||.|||| |.   |||...|                 .   ..|||..... .                     
IVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTT

---QAMTVTVASNPRWSA-PEILRN--------AGSKSTVSPYSKKSDIWSIG
     .  |.   |   | ||.|.         | .  .  .|..|.|.||.|
PTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNA-TDEEKPYYGPKCDMWSCG
Kinase CC1G_13961.AA STE11 320-424 40 2.8e-24 84.83 In-house 124-239 (303) Show / Hide 
Range on Protein: 320-424
Range on HMM: 124-239/303
Sequence Identity: 40% (48 aa)

QITSGLEYLHSQNIVHGDIRGANILISENGV-ALLADFGLSKFLGDIGTVAQA----------MTVTVA----SNPRWSAPEILRNAGSKSTVSPYSKKS
|| .|| ||||..|.| || |||||.  .|.   ||||| .| |  |.| ..           || |.       | | |||.... |..     |..|.
QILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRD----GYGRKA

DIWSIGMTFLELLTGECPYA
||||.| | .| .||  |..
DIWSLGCTVIEMATGKPPWH
Kinase CC1G_13961.AA TyrKc 219-483 24 3.4e-21 77.66 SMART 1-280 (280) Show / Hide 
Range on Protein: 219-483
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

KESEHVAFFGTFNDIYKGRWLNEKMVA---LRLPRSLPNTPRLQRRFEEEVKIWRKL--NHPNVLTLYGITKIG-------QYVYLVSPWMDNGTAINYI
 . ...   | |  .|||.|    .||   |.           .. | .| .| .||  .|||.. |||.   .       . ...|   |..|   .|.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QKNPN----VDRLGLLEQITSGLEYLHSQNIVHGDIRGANILISENGVALLADFGLSKFLGDI-------GTVA-----QAMT-VTVASNPRWSAPEILR
.|. .     | |    || .| |||||.|..| |.   |.|..||...  .|||||....|         .       .. | . .    || ||| . 
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI----RWMAPECI-

NAGSKSTVSPYSKKSDIWSIGMTFLELLT-GECPYAYE----SIDVAVLRLIDNNETPKRPREGKYHHNI-----TDHLWKLMTRCWKMKPDSRPDIAYV
    .  .  .. |||.|| | .  |..| |. ||  .      .  |...... . ...| ..     .     .| . ..|..||. .|..||  . .
----NYGK--FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

RGKL
. ..
HECF
Kinase CC1G_13961.AA TKL-Unique 460-483 29 0.009424 5.75 In-house 267-290 (290) Show / Hide 
Range on Protein: 460-483
Range on HMM: 267-290/290
Sequence Identity: 29% (7 aa)

KLMTRCWKMKPDSRPDIAYVRGKL
.|...||.  |. ||    .. .|
DLIQQCWHHDPSQRPSFDEIIHRL
Kinase CC1G_13961.AA STE11 262-284 39 0.084526 2.64 In-house 57-79 (303) Show / Hide 
Range on Protein: 262-284
Range on HMM: 57-79/303
Sequence Identity: 39% (9 aa)

FEEEVKIWRKLNHPNVLTLYGIT
..||.|. ..|||.|    ||..
IQEEIKLMKHLNHKNIVRYYGCC
RasGEF_N CC1G_13961.AA RasGEF_N 813-910 25 2e-10 35.43 Pfam 1-104 (104) Show / Hide 
Range on Protein: 813-910
Range on HMM: 1-104/104
Sequence Identity: 25% (27 aa)

RVTAGTLQGLVERLINNFNLQKDMEFRDVMLTACIDFITPEDMFNILIRRFEDAEQGSDMR-----PELRLGIQYTIFKVLMYWLLGR-HL---PVNTAL
.| .|||..|||..... ..  |..|  ..|.    |.|| . .. ||.|.. ...  .        . .  ||  ...||..|.    .    . . .|
QVKGGTLEKLVEHCTHHHFHDPDPTFVETFLLTYRSFTTP-ELLEKLIQRYHWPPP-NNHYNSKWNKKYV-PIQIRVCNVLRHWVENHSWYQDFDDDPQL

LWRMEEF
| |.|||
LQRLEEF
RasGEFN CC1G_13961.AA RasGEFN 809-939 14 0.000528 1.5 SMART 1-172 (172) Show / Hide 
Range on Protein: 809-939
Range on HMM: 1-172/172
Sequence Identity: 14% (26 aa)

TNADRVTAGTLQGLVERLINNFN-----LQKDMEFRDVMLTACIDFITPEDMFNILIRRFEDAEQG----------------------------------
 .  |. .|||  |.|.|.. |      .  |. | ...|.    |.||.. ...||.|.. ..                                    
CDGHRIKGGTLEKLIEHLTHHFDKGMVQFCDDPQFCETFLMTYRSFCTPQELCQKLIHRYNCIPPYIHYRSKELQQTEAREGLCFEDYSHNHFYCWFQTW

--SDMRPELRLGIQYTIFKVLMYWLLGRHLPVNTALLWRMEEFCQS-AIKLKTSQP-MIMKGNELLQLIEERIA
   . ... .. ||  .  ....|.   . ...  .   | .. .   |.. . ..  .... ..|| | .|. 
NIWNKEKHNPRRIQNRVCNIMRHWVE--NHWQDFYDDPKMNMMLWELFIHVVDQYHDKYPQWHKSLQNILCRLS
RasGEF CC1G_13961.AA RasGEF 962-1181 19 2e-06 -30.68 SMART 1-261 (261) Show / Hide 
Range on Protein: 962-1181
Range on HMM: 1-261/261
Sequence Identity: 19% (51 aa)

SSQITPRDLAIALTLLEGDKFRKIQP---CDYLAHQRRQPISGYLNH--VKAAAIVNTRIVQWVKQSILHFDE--VRHRADVIKFYINTARNL-------
  .. |..||  |||..   |.||.|    |.. |... .. . | .  ...   .  ....||  .||   .  .. || ||.. |. |. .       
FLHFDPWELAEQLTLMDWELFCKIHPFECLDCVWHHCHKKSPSHLCPQNIHRFIRRFNCVSNWVATMILKCTTMHPKKRAQVIEKWIQVAKHCRELNNFN

-----------------------LSEKFKKWLNEIVSILYPM-DDYAAYRSALREIH-DPQYADYCIPWLELHLDQLALLLRENSRVVEIDHHPLINFKR
                       ...|.|| . |. ... |  . | .|| .|....  |     ||| . ..|  |. .   |   .|  .  ||||  
SMMAIMSALQSSPIYRLKKTWEHVPHKYKKLFEELCELMDPSERNYKNYREHLKSCNWMPNQQPPCIPFFGVYLKDLTFIHEGNPDWLENHTKNLINFEK

YLEYVKQFKSVLGFTPA-DLEEYRDQ-GQLAYLEHQLAGIEVTDSADDEMMKRSLELEQGE
    ..   ..  .. | . .. ...  .. ... |.  ... .. .|| ...||..|  .
RRMMFNIIREIRQWQSACQHYNFQPNHMDIQWWLQQWRYLDHLPEENDEQYQLSLRIEPRV
RasGEF CC1G_13961.AA RasGEF 1048-1125 25 8e-06 22.14 Pfam 123-204 (204) Show / Hide 
Range on Protein: 1048-1125
Range on HMM: 123-204/204
Sequence Identity: 25% (22 aa)

LSEKFKKWLNEIVSILYPMDDYAAYR--SALR-EI-HDPQYADYC-IPWLELHLDQLALLLRENS-RVVEIDHHPLINFKRY-LE
.. | || ..|  ... | .....||   ||.  . |.||  . | || . ..|  |  .   |.   ..  . .||||...   
VPKKYKKTFEELEKLMSPEKNFKNYRHDEALKGKCKHNPQ--KPCFIPFFGVYLKDLTFIHEGNPKDFINNGT-KLINFEKRFRM
RasGEF CC1G_13961.AA RasGEF 963-993 31 0.044818 8.84 Pfam 1-32 (204) Show / Hide 
Range on Protein: 963-993
Range on HMM: 1-32/204
Sequence Identity: 31% (10 aa)

SQITPRDLAIALTLLEGDK-FRKIQPCDYLAH
 .. |...|  |||.| .  |..|.| ..| .
LDFDPEEIARQLTLIEWELWFCAIHPRECLDC
RasGEF CC1G_13961.AA RasGEF 1014-1047 32 0.062869 8.32 Pfam 59-92 (204) Show / Hide 
Range on Protein: 1014-1047
Range on HMM: 59-92/204
Sequence Identity: 32% (11 aa)

TRIVQWVKQSILHFDEVRHRADVIKFYINTARNL
.....||  .||  . ...|| |||. |..|...
NHLSNWVATEILSEEDPKKRAKVIKKWIKIAQHC