Gene DC2.7b (Nematode worm)

DC2.7b

Species: Nematode worm
Alias: aSWK040, DC2.7, DC2.7a, DC2.7b, WP:CE20636, Y, 77229.41
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CHK1

Sequence

Name Sequence Type Origin Length Description Download
DC2.7b.AA Protein None 318 None Fasta, JSON
DC2.7b.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of DC2.7b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DC2.7b.AA CHK1 21-290 53 6.9e-187 627.15 In-house 1-276 (276) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-276/276
Sequence Identity: 53% (147 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQS-ERFVEH-IKTEFAIHKGLSKIGGHRNVISMMEMRKGSDCYTLLKEYADGGDLFKKLETEG
|.||..|.||..|||.|.|...||....|.|.|...||. ..|... |..|..|.|.|||||.|.|||.||.||.....|.|..|||||||||.|.|...
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYYLFMEYADGGDLFDKIEPDC

EQYSENAQCFFKQLISGLKFIHEHE-IVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYM-VDGEELMLVDNCGSPPYAAPEVYSKQGHRGPPTDVW
...|..|...|||||||||.||... ..|||||.|||||.|..||..||.||||||||||.|. .||||.||...||.|||.||||......||||.|.|
GMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKRCGTPPYMAPEVCTGKQYRGPPVDIW

SSGVILMAMLTAGLPWDCAH-RKDVDYAAWIDKK-FRTDNLWNDISDRALALLRKILCVNVSERVSIEQIEADPWF
|.||.||||||..||||..    . .|..|.|.| ......|..|..||..|||||||.|...|..|||||.|||.
SCGVVLMAMLTGELPWDQPSHMDCQEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIEQIEKDPWY
Kinase DC2.7b.AA CAMKL 21-290 30 7.69999999999e-110 351.73 In-house 1-297 (297) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-297/297
Sequence Identity: 30% (94 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQS-ERFVEH------------IKTEFAIHKGLSKIGGHRNVISMMEMRKGSDC------YTLL
|.... | .|..|.| | .  ... .| |.| |   . . . ...             |. | .|.| |. ||.| |.|...|..  ...      . | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

KEYADGGD--LFKKLETEGE----QYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYM-V-DGEELMLVDNCG
 ||..||.  || ... .|.       . |. .|.|..|.....|.| |||||||.||.|| ....|    ..||.|||....|. . .|.. .|   ||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

SPPYAAPEVYSK--QGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRK-----DVDYAAWIDKKFRTD-NLWNDISDRALALLRKILCVNVSERVSIEQIE
||||.|||....  . ..||..|.|| |||| ||..  ||.|... .     .. |  |....  .  . |...| ..  |.||.| || ..| .|.||.
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

ADPWF
 .||.
NHPWM
Kinase DC2.7b.AA CAMK 26-290 20 5.4e-82 263.86 In-house 1-425 (425) Show / Hide 
Range on Protein: 26-290
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

FLSEGTYGQVSLYESSKNPD-----------VKIAVKQISTAGQSE-------------------------RFVEH-IKTEFAIHKGLSKIGG---HRNV
 | .|..|.| | .  ...            .| |.| |..   ..                          . .. .. | .|.| |..||.   |.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISMMEMRK--------------------GSDCYTLLK--EYADGG----DLFKKLETEGE---------------QYSENAQCFFKQLISGLKFIHEHEI
|.. |.                       ...|  ..  ||..||    ||| ..   |                   . |. .|.|..|.....|.| |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKLENLLLMKSKSNLVP-----------DTLKIADFGLATEYMVDGEEL---------------------MLVDNCGSPPYAA-PEVYSK------
||||.|.||.|| .....  |            ..||.|||.|.... . ...                     .. . ||.|.|.| ||| ..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRK-----------------DVDYAAW--IDKKFR------TDNLWNDISDR--------ALA
       .   ||..|.|| |||| .||.  .|..  ...                  .  . .  ....|       ..  |.||||         .  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRKILCVNVSERVSIEQIEADPWF
|.||.|.|. ..| .|||. ..||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DC2.7b.AA S_TKc 21-290 27 1.9e-65 224.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSERFVEHIKTEFAIHKGLSKIGGHRNVISMMEMRKGSDCYTLLKEYADG--GDLFKKLETEG
| ..| . .|..|.| .    |  . . |.|.|.         |||. | .|.|      .| |.. . ..    |.. .  ||.||  ||||. ..  |
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

EQ-----YSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQGHRGPPT
 .     ..| |.....|....|...|.| |.|||.| ||.|| .        ..||.|||||...            ||.| | ||||    |. ... 
RHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKC

DVWSSGVILMAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDRALALLRKILCVNVSERVSIEQIEA-------DPWF
|.|| |.||  ||.   |..       .... ..|           |. |. ..||.|... ..| .. .. .       .|||
DWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DC2.7b.AA Pkinase 21-290 25 7.1e-56 196.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVK-IAVKQISTAGQSERFVEHIKT--EFAIHKGLSKIGGHRNVISMMEMRK-GSDCYTLLKEYADGG----DLFK
| ..| . .|..|.|  |.  .  . |  |||.|.  .... . ..     | .|.| |.    | |.. . ..   ....| .  ||..||    ||| 
YHIGRKIGSGSFGCV--YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFD

KLE--TEGEQ--YSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEVYSKQGH
 ..   .|      . ......|...||...|.. |.|||.|.||.|.  .. .. . ..||.|||||  .        . . ||.|.|.||||  .. .
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA-CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQY

RGPPTDVWSSGVILMAMLTAGLPWDCAH------RKDVDYAAWIDKKFRTDNL-WNDIS-----------------DRALALLRKILCVNVSERVSIEQI
 ||. |.|| |.||  ||.  .|..  |      .... ..   ..... |   |..||                 . .. .....||.. ..| ..|||
YGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

EADPWF
  .|||
LQHPWF
Kinase DC2.7b.AA AMPK 103-290 40 3.4e-51 150.25 In-house 80-254 (254) Show / Hide 
Range on Protein: 103-290
Range on HMM: 80-254/254
Sequence Identity: 40% (76 aa)

EYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAAPEV
||. ||.||      |    . |. ||.| |||.  .|.| ||||| |.||||| . |.      .||.||||   .| |||  .|   |||| |||||.
EYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKN------IKIVDFGLS-NMMKDGE--FLKTACGSPCYAAPEM

YSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNLWNDISDRALALLRKILCVNVSERVSIEQIEADPWF
 | .   || .|.||.|||| ||| . || |  .  .  |.  .. ..    .  ..|..|  |....|.|.  .|..|..| ..|||
ISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTL-YKKIKNGEYY---IPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase DC2.7b.AA Ciliate-E2 21-290 19 4.7e-48 163.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-365/365
Sequence Identity: 19% (77 aa)

YNVVRFLSEGTYGQVSLYESSKNPDV-----------------KIAVKQISTAGQSERFVEHIKTEFAIHKGLS------------KIGGHRNVISMMEM
|.... . .|..|.| . .  |..                   | ..|..    .... .|.|| |  | . .             ..  | |.| | | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

RK--GSDCYTLLKEYADGGDLFKKL------------ETEGEQYSENAQC-FFKQLIS---------------GLKFIHEHE-IVHRDIKLENLLLMKSK
 .    ... |  ||..|||||. .            . . ....|.  . ..||...               .|...|.   |.|||||.||.|.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

SNLVPDTLKIADFGLATEYMVDGE--------ELMLVDN----------------------CGSPPYAAPEVYSKQG--------HRGPPTDVWSSGVIL
       .||.||||...|  | .        ....  .                      ||.|.| |||......        . .   |.|| ||||
-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

MAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNL---------------WNDISDRALALLRK----ILCVNVSERVS-IEQIEADPWF
  ||.  .|.         .   ...|.. ..                |...|. .  |..|    .|... ..| . .|||   |||
YEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DC2.7b.AA ULK 21-290 24 6.3e-44 151.24 In-house 1-329 (329) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-329/329
Sequence Identity: 24% (82 aa)

YNVVRFLSEGTYGQVSLYESSKNP---DVKIAVKQISTAGQSERFVE--------HIKTEFAIHKGLS-------KIGGHRNVISMMEMRKGS--DCYTL
|.. . | .|..|.|   .  |.    ..|.|.|.|.   ...   |         .| |  | | |        .   | |.. . .. . |  ... .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNH---HPNIVKLYDWFETSNHNNIYI

LKEYADGGDLFKKLETEGE----------QYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSK-------SNLVPDTLKIADFGLATEYMVDG
  || .||||.. ... ..             . |. ||||...|.|..|.| |.|||||..| |. . .       ..    .|||||||.|   . |.
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDN

-EELMLVDNC------GSPPYAAPEVYSKQGHRGPPT----DVWSSGVILMAMLTAGLPWDCAHRKDV-----DYAAW-------IDKKFRTDNLW---N
 |. |..         |.| | ||.. ..|| . |..    |.|| |.|.  ||.   |. .  ....     .   .       |.|.    .     .
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

DISDRALALLRKILCVNVSERVSIEQIEADPWF
 ||.    |.|. |... ..| |.|.. . |||
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase DC2.7b.AA ULK 21-290 24 7.9e-42 145.28 In-house 1-324 (324) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-324/324
Sequence Identity: 24% (79 aa)

YNVVRFLSEGTYG-QVSLYESSKNP--DVKIAVKQISTAGQSERFVE--------HIKTEFAIHKGLSKIGGHRN--VISMMEMRKGSDC--YTLLKEYA
|.. . | .|..| .|   .  |.   ....|.|.|.  ....   |         .| |  | | |  .  | |  .. . .. . |..  . .  || 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKEL-KHPNHHIVKLYDWFETSNHNNIYIIMEYC

DGGDLFKKLETEGE---------QYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSK-------SNLVPDTLKIADFGLATEYMVDGEELML-
.||||.. ... ..            . |. ||||...|.|..|.| |.|||||..|.|. . .       ..    .|||||||.|   . ...| .. 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMC

VDNC------GSPPYAAPEVYSKQGHRGPPT----DVWSSGVILMAMLTAGLPWDCAHRKDV----------------DYAAWIDKKFRTDNLWNDISDR
   .      |.| | ||.. ..|| . |..    |.|| |.|.  ||.   |. .  ....                 .  .|...       . ||. 
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP--KDPKISPE

ALALLRKILCVNVSERVSIEQIEADPWF
   |.|. |... ..| |.|.| . |||
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase DC2.7b.AA Ciliate-E2-Unclassified 21-290 20 7.1e-39 132.49 In-house 1-352 (352) Show / Hide 
Range on Protein: 21-290
Range on HMM: 1-352/352
Sequence Identity: 20% (74 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSE-RFVEHIKTEFAIH-KGLSKIG------------------GHRNVISMMEMRKGSDCYTL
|.... . .| .|.| . . .|.   . | |... . .   . ... . |.    | . ..                    | ... |... .  ..  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

LKEYADGGDLFKKLETEGE----------------QYSENAQC------FFKQLISGLKFIHEHE-IVHRDIKLENLLLMKSKSNLVPDTLKIADFGLAT
  ||..||||.. ..  .                 . .|.. .      .|.|...||...|.   |.|||||.||.|. ....|.    .||.|||.. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYY---IKIIDFGISK

EYMV----DGEEL----------MLVDNCGSPPYA----APEVYSKQGHRGP---PTDVWSSGVILMAMLTAGLPWDCAHRKD--------------VDY
.|      | ..           |. ..||.| |     ||||. .|.. ..     |.|| |||| .||.  .| ..  ...                .
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

AAWI-DKKFRTDNLWN-----DISDRALALLR----KILCVNVSERVSIEQIEADPWF
  .| .|..  .. ..     ..|. |  ...    |.| .| ..| ..|||   |||
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase DC2.7b.AA MARK 103-290 34 2.3e-38 123.13 In-house 82-262 (262) Show / Hide 
Range on Protein: 103-290
Range on HMM: 82-262/262
Sequence Identity: 34% (66 aa)

EYADGGDLFKKLETE--GEQYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSK-SNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAA
||| ||.|.  ..    |    | |  .|.|..|.... |.. |||||||.||.|. . .  |      ||.|||.... . .     |   ||.|||.|
EYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHN-----IKIIDFGFSICIPPGQK---LNTFCGTPPYMA

PEVYSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRKDVDYAAWIDKKFRTDNLW--NDISDRALALLRKILCVNVSERVSIEQIEADPWF
||. .|.   ||..|.|| ||.| .|..  .|.|    ...||   . || .. . .    .|. .  |....| || .|| .||.|. .||.
PEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD---GDTQDYKE-LYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase DC2.7b.AA BRSK 100-233 44 2e-32 107.75 In-house 77-201 (254) Show / Hide 
Range on Protein: 100-233
Range on HMM: 77-201/254
Sequence Identity: 44% (60 aa)

LLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDNCGSPPYAA
|. |.  || ||  |   |   .  |  ||.| ||.| | | | | ||| | |||||   .        ||||||.|    .  .. ||   |||| || 
LILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKN------NIKIADFGMAS---LQVKDMMLHTSCGSPHYAC

PEVYSKQGHRGPPTDVWSSGVILMAMLTAGLPWD
||| .     |   |||| |||| |.|.  || |
PEVIRGEKYDGRKADVWSCGVILYALLVGALPFD
Kinase DC2.7b.AA TyrKc 21-288 19 6.5e-11 -46.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

YNVVRFLSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSERFVEHIKTEFAIHKGLSKIG-GHRNVISMMEMRKGS-------DCYTLLKEYADGGDLFK
    . | || .|.| . . .    .. ||| .         .| .  |  |   ..|.|  | |.. .      .       . . .. ||...||| .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARI---MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

KLETEGEQYSENAQCFF-KQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVD-----GEELMLVDN--CGS--PPYA--AP
 |   ... .    . |  |  .|  ..|.. ..|||.   | |. . .      | ||.||||. .   |      ..   .    .|    |.   ||
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EVYSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAH----RKDVDYAAWIDKKFRTDNLWND-------ISDRALALLRKILCVNVSERVSIEQIEADP
|.  . |   . .|||| || .  ..| | .          .. .  ..... .| .   ||        .|    . ..    . ..| . ..|  . 
ECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DC2.7b.AA BRSK 266-290 36 1e-06 18.87 In-house 230-254 (254) Show / Hide 
Range on Protein: 266-290
Range on HMM: 230-254/254
Sequence Identity: 36% (9 aa)

LLRKILCVNVSERVSIEQIEADPWF
|||. . |. . |.|...|.  ||.
LLRGMIEVDPDKRISLKEIQKHPWY
Kinase DC2.7b.AA MARK 21-35 26 0.055303 2.47 In-house 1-15 (262) Show / Hide 
Range on Protein: 21-35
Range on HMM: 1-15/262
Sequence Identity: 26% (4 aa)

YNVVRFLSEGTYGQV
| ... . .|.|..|
YKMLKTIGHGSYAKV