Gene n1186 (Tetrahymena)
n1186
Species: Tetrahymena
Alias: 1186, n1186, 314.m00893
External Links:
Annotation:
Group:
Other
Family:
Ciliate-B2
Sequence
Protein domains of n1186.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | n1186.AA | Ciliate-E1 | 36-217 | 22 | 2.2e-17 | 53.48 | In-house | 8-202 (202) | Show / Hide |
Range on Protein: 36-217 Range on HMM: 8-202/202 Sequence Identity: 22% (44 aa) ITFDGVQLSDG---QQVKIQITIC--DEQLFEKKKRIYF-VNQTINNFEFCIKILKQILIDQEKICIFIFENYEETLEEELC---------EMKKQNINF | |...| .. ..||. ... ... |..... |. . . ... . |.|...| ||| .|||.|||.....|...| ........| IVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQF SEKQIVQMYMNMIYSLIEMCSLNIVHGEINPSNIFRKSNGKYKLL-NGQNLSFQEFQELYSEENLYNIFVAPEVKQKLSLMQTNEFQKSHAKWQQDVY ...|..|. ...| |||. ..|| |. |.|.|| ...|.|.. |. . ... |. .. .. | ..|. . . .| .. .. . . |.| TFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCP-EQ-EHNKNQKINYKSDIY |
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| Kinase | n1186.AA | Ciliate-B2 | 81-164 | 34 | 3.9e-16 | 34.34 | In-house | 63-145 (197) | Show / Hide |
Range on Protein: 81-164 Range on HMM: 63-145/197 Sequence Identity: 34% (29 aa) IKILKQILIDQEKICIFIFENYEETLEEELCEMKKQNINFSEKQIVQMYMNMIYSLIEMCSLNIVHGEINPSNIFRKSNGKYKL .|.. | | .|.| ..| | | |..|| ..|| ..| .. ..|| ..| ||.. . ||.| .|.|.|| .||.|.. VKYIDHIQI-NETIDVLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVY |
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| Kinase | n1186.AA | Ciliate-E4 | 106-166 | 29 | 4.4e-08 | 23.53 | In-house | 90-150 (150) | Show / Hide |
Range on Protein: 106-166 Range on HMM: 90-150/150 Sequence Identity: 29% (18 aa) LEEELCEMKKQNINFSEKQIVQMYMNMIYSLIEMCSLNIVHGEINPSNIFRKSNGKYKLLN |. .. |.|.. |.| | |. . | .. . || ||.. ||||| . |.. LQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | n1186.AA | Ciliate-C8 | 85-223 | 21 | 0.000271 | 11.68 | In-house | 75-238 (238) | Show / Hide |
Range on Protein: 85-223 Range on HMM: 75-238/238 Sequence Identity: 21% (36 aa) KQILIDQEK----ICIFIFENYEET--LEEELCEMKKQNINFSEKQIVQMYMNMIYSLIEMCSLNIVHGEINPSNIFRKSNGKY----KLLN-------G ..| .||| . | ... |.. . ...|... .|... .. || |. . ||.| | |.|. . .| || . | DKIVQTQEKIKKSFFVMEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFG QNLSFQEFQE-LYSEE--NLYNI----------FVAPEVKQKLSLMQTNEFQKSHAKWQQDVYSMGLCF . . .. ..|.. . . . . |||| .| | | |.| |.|| ||.. FASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKK-----SDSYSVGLVL |
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| Kinase | n1186.AA | Ciliate-C3 | 143-167 | 44 | 0.000391 | 11.18 | In-house | 116-140 (140) | Show / Hide |
Range on Protein: 143-167 Range on HMM: 116-140/140 Sequence Identity: 44% (11 aa) NIVHGEINPSNIFRKSNGKYKLLNG |||||.| .||| |... |.. NIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | n1186.AA | Ciliate-B2 | 212-220 | 66 | 0.002965 | 3.39 | In-house | 189-197 (197) | Show / Hide |
Range on Protein: 212-220 Range on HMM: 189-197/197 Sequence Identity: 66% (6 aa) WQQDVYSMG .| |.|||| FQSDIYSMG |
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| TPR | n1186.AA | TPR | 359-392 | 32 | 0.000265 | 21.54 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 359-392 Range on HMM: 1-34/34 Sequence Identity: 32% (11 aa) ALAYLELGIIKVNTQKYSDSLEAYQKSLEIQKRI | |.. || . . .| . .|.|||.||.. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | n1186.AA | TPR_1 | 359-392 | 32 | 0.000314 | 18.75 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 359-392 Range on HMM: 1-34/34 Sequence Identity: 32% (11 aa) ALAYLELGIIKVNTQKYSDSLEAYQKSLEIQKRI | |. || . . ..| . .|.||| ||.. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | n1186.AA | TPR_2 | 359-392 | 26 | 0.000532 | 18.24 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 359-392 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ALAYLELGIIKVNTQKYSDSLEAYQKSLEIQKRI | |. || . . ..| . .|.|.|.|.. . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_2 | n1186.AA | TPR_2 | 443-476 | 23 | 0.023966 | 12.39 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 443-476 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) ADSLSCVGFSYLQKNDLQKALEYSQKSFEMRKEL |. . . | .|....|...|.|| .|. . . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | n1186.AA | TPR | 443-476 | 26 | 0.033566 | 13.54 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 443-476 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ADSLSCVGFSYLQKNDLQKALEYSQKSFEMRKEL |. ... | .|....|...|.|. ||. |. . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | n1186.AA | TPR_1 | 443-476 | 23 | 0.040874 | 11.37 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 443-476 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) ADSLSCVGFSYLQKNDLQKALEYSQKSFEMRKEL |. .. | |........|.|. || |.. . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_3 | n1186.AA | TPR_3 | 443-476 | 13 | 1.722543 | 5.2 | Pfam | 1-38 (38) | Show / Hide |
Range on Protein: 443-476 Range on HMM: 1-38/38 Sequence Identity: 13% (5 aa) ADSLSCV--GFSYLQKNDLQKALEYSQ--KSFEMRKEL | . . .... .| ..|.|... | ....... MDYWYSYWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN |
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| TPR_2 | n1186.AA | TPR_2 | 485-518 | 26 | 0.042769 | 11.5 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 485-518 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) AGSLEEIGIVFTHMKDHITAHTYYERALQIRQQI | . .| . ...|. |. |||.||.. . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | n1186.AA | TPR | 485-518 | 23 | 0.151047 | 7.8 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 485-518 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) AGSLEEIGIVFTHMKDHITAHTYYERALQIRQQI | . .| .. .|.|. | .|..||.. . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | n1186.AA | TPR_1 | 485-518 | 20 | 0.159082 | 9.31 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 485-518 Range on HMM: 1-34/34 Sequence Identity: 20% (7 aa) AGSLEEIGIVFTHMKDHITAHTYYERALQIRQQI | . .| .. .|... | .|..||... . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | n1186.AA | TPR | 527-560 | 23 | 0.343884 | 4.66 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 527-560 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) AKSYDSLAVSFSKLGQEETSLEFDLKALNIRQQI |. . |.... |.|. . .|. ||| . . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR | n1186.AA | TPR | 569-602 | 26 | 0.055659 | 11.61 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 569-602 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ARSINNISISYLKLSDYTKALEYAQESYGIRKQI |. .|. .|.|. || .|.|. |.. . . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | n1186.AA | TPR_2 | 569-602 | 26 | 0.10229 | 10.16 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 569-602 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ARSINNISISYLKLSDYTKALEYAQESYGIRKQI |. .|. .|.|. || .|.|| ... . . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_1 | n1186.AA | TPR_1 | 569-602 | 23 | 0.670137 | 7.13 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 569-602 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) ARSINNISISYLKLSDYTKALEYAQESYGIRKQI |. .|. |.|. .| .|.|. |. .. . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_1 | n1186.AA | TPR_1 | 611-644 | 41 | 9.6e-09 | 34.51 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 611-644 Range on HMM: 1-34/34 Sequence Identity: 41% (14 aa) AESLSTLGSIYYRLENYEEAIKCYQQTIKIFSQI || .. || .||...||.|||.|||. ... . AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | n1186.AA | TPR | 611-644 | 38 | 2.3e-08 | 35.02 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 611-644 Range on HMM: 1-34/34 Sequence Identity: 38% (13 aa) AESLSTLGSIYYRLENYEEAIKCYQQTIKIFSQI || .. || .||....|.|||.|||. ... . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | n1186.AA | TPR_2 | 611-644 | 35 | 3e-08 | 33.29 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 611-644 Range on HMM: 1-34/34 Sequence Identity: 35% (12 aa) AESLSTLGSIYYRLENYEEAIKCYQQTIKIFSQI || . || .||....|.|||..|.. .|.. . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_3 | n1186.AA | TPR_3 | 611-644 | 13 | 0.00268 | 14.77 | Pfam | 1-38 (38) | Show / Hide |
Range on Protein: 611-644 Range on HMM: 1-38/38 Sequence Identity: 13% (5 aa) AESLSTL--GSIYYRLENYEEAIKCYQ--QTIKIFSQI . . .. . .| ..|..|.. || . ..... MDYWYSYWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN |
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| TPR_2 | n1186.AA | TPR_2 | 653-686 | 41 | 0.037795 | 11.69 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 653-686 Range on HMM: 1-34/34 Sequence Identity: 41% (14 aa) VDSYLSLSQCYKKQGDIKSALAYELKLLKLREKL .. . | ||| |||| . |..| |.||| .. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | n1186.AA | TPR | 653-686 | 29 | 0.041721 | 12.71 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 653-686 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) VDSYLSLSQCYKKQGDIKSALAYELKLLKLREKL .. .. | .|| |.||.. |... | |.| .. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | n1186.AA | TPR_1 | 653-686 | 26 | 1.440391 | 5.97 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 653-686 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) VDSYLSLSQCYKKQGDIKSALAYELKLLKLREKL .. . | .|| |.|. . |... | |.|... AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | n1186.AA | TPR | 741-774 | 11 | 0.429659 | 3.81 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 741-774
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)
LNSIKNIALSYLNQGKFEKSRQYFSIVFESILHQ
.|....|...|.... .... . | .
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
|
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| TPR_1 | n1186.AA | TPR_1 | 741-764 | 12 | 0.88407 | 6.71 | Pfam | 1-24 (34) | Show / Hide |
Range on Protein: 741-764 Range on HMM: 1-24/34 Sequence Identity: 12% (3 aa) LNSIKNIALSYLNQGKFEKSRQYF . .|... |...|.... ... AEAWYNLGNCYYKMGNYDEAIECY |
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| TPR_2 | n1186.AA | TPR_2 | 741-764 | 20 | 1.614695 | 5.92 | Pfam | 1-24 (34) | Show / Hide |
Range on Protein: 741-764
Range on HMM: 1-24/34
Sequence Identity: 20% (5 aa)
LNSIKNIALSYLNQGKFEKSRQYF
|....|..||.... ..|.
AEAWYNLGQCYYKQGDYDEAIEYY
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| TPR_3 | n1186.AA | TPR_3 | 741-765 | 7 | 7.875208 | 2.95 | Pfam | 1-27 (38) | Show / Hide |
Range on Protein: 741-765 Range on HMM: 1-27/38 Sequence Identity: 7% (2 aa) LNSIKNI--ALSYLNQGKFEKSRQYFS .. .. | .. ...|... ..... MDYWYSYWLAYTFYMKKKYQQAYHLYQ |
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