Gene n1180 (Tetrahymena)
n1180
Species: Tetrahymena
Alias: n1180, 1180, 3812.m02689
External Links:
Annotation:
Group:
Other
Family:
Ciliate-E4
Sequence
Protein domains of n1180.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | n1180.AA | Ciliate-A5 | 59-319 | 23 | 9.4e-27 | 89.8 | In-house | 3-275 (275) | Show / Hide |
Range on Protein: 59-319 Range on HMM: 3-275/275 Sequence Identity: 23% (65 aa) GNVDVYKCIHNKNFRIYLKEMFTKSEEELNQQVEMWVKRQSLLLHPNLIQLHSCCHQKVESFCATFFKIFMLFDSVEADLLNTIKKDRIQK----FSEDE | . .| |. |. . . .| . . .. .|. | |||...| . .| |.|| .|.|. .. . .| . . . .. ..|.| GCMKIWKNQHQQEYYICKQKQI-QDEDRQKHFQQYFEQRM-QLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQE LWFLLDSIVGVLEFMQERDLTHQSLRLDTIYINSNHKNIKLFKLADSQ-----LM-GYTTNYENQLTQFDKYI--YLSPLLFTQYGNN----IEHPVHNE ||...|... |. ..|.... | .| .| . . . .||.|. . . | .. . . ||||... | .. | |.||. LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQ----VKLMDMNESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNW YKSDVFTLGMLLVHLSLFESC-ADVYSLIDHS-INQQV-LNDKLSRISN-TYSSDYSQIIQEMCILDEKYRPDFRSLDRKL ||||||.|||.. . . ..| ..| . . ..| . | ..| || .| .| ...| .|||| . | YKSDVFCLGMICLEMCTMRDCTQFYYD--YETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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Kinase | n1180.AA | Ciliate-E4 | 74-197 | 24 | 8.3e-16 | 49.46 | In-house | 27-150 (150) | Show / Hide |
Range on Protein: 74-197 Range on HMM: 27-150/150 Sequence Identity: 24% (31 aa) IYLKEMFTKSEEELNQQVEMWVKRQSLLLHPNLIQLHSCCHQKVESFCATFFKIFMLFDSVEADLLNTIK--KDRIQKFSEDELWFLLDSIVGVLEFMQE | .| .|... || .|| | |.|.|.. |.|.. || .. .. .... . || || | . |.|.|.|.| .. . . . . | IVMKIRKFQNETKARQQQQQFRRRQD-LNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQ RDLTHQSLRLDTIYINSNHKNIKLFK .||. |. | . .. .|. VNITHGDLKPSNIFF-DQYFMVKIAD |
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Kinase | n1180.AA | S_TKc | 63-326 | 14 | 6e-07 | -74.98 | SMART | 15-231 (231) | Show / Hide |
Range on Protein: 63-326 Range on HMM: 15-231/231 Sequence Identity: 14% (42 aa) VYKCIHNK-NFRIYLKEMFTKSEEELNQQVEMWVKRQSLLLHPNLIQLHSCCHQKVESFCATFFKIFMLFDSVEA---DLLNTIKKDRIQK----FSEDE ||||.|.| . . .|.. .... .. . |||...|. ... ...| .. .. ||. ||| . .. |.| . VYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H LWFLLDSIVGVLEFMQERDLTHQSLRLDTIYINSNHKNIKLFKLADSQLMGYTTNYENQLTQFDKYI----YLSPLLFTQYGNNIEHPVHNEY-KSDVFT .|.. |. ||.. .. | | . | ... .||. . .. . .. |..| .. . . |.|. ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-----------GYGKCKCDWWS LG----MLLVHLSLFESCADVYSLIDHSINQQVLNDKLSRISNTYSSDYSQIIQEMCILDEKYRPDFRSLDR--KLSSCPKLF .| .|. .|. ... .... |.. ..|. .. | . || . . . | | CGCILYEMLCGYPPFP---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | n1180.AA | TBCK | 166-197 | 25 | 2e-05 | 15.25 | In-house | 93-127 (346) | Show / Hide |
Range on Protein: 166-197 Range on HMM: 93-127/346 Sequence Identity: 25% (9 aa) LEFMQERDLTHQSLRLDTIYINSNHK---NIKLFK | .| ....| .| .. ||...| . .||.. LSYMHKHHIVHRFLHPHNIYLDDNGNQKLHVKLAN |
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Kinase | n1180.AA | CDK | 101-138 | 33 | 0.000675 | 8.17 | In-house | 65-104 (284) | Show / Hide |
Range on Protein: 101-138 Range on HMM: 65-104/284 Sequence Identity: 33% (14 aa) LLHPNLIQLHSCCHQK--VESFCATFF--KIFMLFDSVEADL | ||| ..|| .||.| .. .... |..| |. .. || L-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFEYMDHDL |
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Kinase | n1180.AA | TBCK | 243-259 | 41 | 0.190615 | 0.8 | In-house | 183-199 (346) | Show / Hide |
Range on Protein: 243-259 Range on HMM: 183-199/346 Sequence Identity: 41% (7 aa) YKSDVFTLGMLLVHLSL .|||| ||. .... | PKSDVWSLGCIMLEICL |
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MORN | n1180.AA | MORN | 631-652 | 54 | 1.4e-08 | 35.8 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 631-652 Range on HMM: 1-22/22 Sequence Identity: 54% (12 aa) QKYEGEWQNNKRHGKGTQYFQN .|||||.|.||||.|. .. | DRYEGEWHNGKRHGHGVYWWAN |
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MORN | n1180.AA | MORN | 633-655 | 47 | 1.6e-08 | 35.7 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 633-655 Range on HMM: 1-23/23 Sequence Identity: 47% (11 aa) YEGEWQNNKRHGKGTQYFQNGSI |||||.|.|.||.|. .. .|. YEGEWKNGKMHGHGVYTWPDGDR |
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MORN | n1180.AA | MORN | 610-632 | 39 | 1e-06 | 29.0 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 610-632 Range on HMM: 1-23/23 Sequence Identity: 39% (9 aa) YEGDVLDGKKHGYGVFIFSNQQK |||. .||.||.||..... . YEGEWKNGKMHGHGVYTWPDGDR |
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MORN | n1180.AA | MORN | 608-629 | 45 | 4e-06 | 27.45 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 608-629 Range on HMM: 1-22/22 Sequence Identity: 45% (10 aa) NIYEGDVLDGKKHGYGVFIFSN ..|||. .||.||.||....| DRYEGEWHNGKRHGHGVYWWAN |
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MORN | n1180.AA | MORN | 657-676 | 40 | 8.3e-05 | 22.22 | Pfam | 1-20 (23) | Show / Hide |
Range on Protein: 657-676 Range on HMM: 1-20/23 Sequence Identity: 40% (8 aa) YEGQWEDDQYHGFGTLFYKD |||.| ... ||.|.. ..| YEGEWKNGKMHGHGVYTWPD |
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MORN | n1180.AA | MORN | 655-676 | 31 | 0.000274 | 21.03 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 655-676 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) IKYEGQWEDDQYHGFGTLFYKD .|||.| ... ||.|.. ... DRYEGEWHNGKRHGHGVYWWAN |
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MORN | n1180.AA | MORN | 734-756 | 43 | 5e-06 | 26.6 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 734-756 Range on HMM: 1-23/23 Sequence Identity: 43% (10 aa) YEGDFKYGKKDGFGTITFSNNDY |||..| ||..|.|. |... |. YEGEWKNGKMHGHGVYTWPDGDR |
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MORN | n1180.AA | MORN | 732-753 | 36 | 0.000455 | 19.38 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 732-753 Range on HMM: 1-22/22 Sequence Identity: 36% (8 aa) VKYEGDFKYGKKDGFGTITFSN .|||... ||..|.|. ...| DRYEGEWHNGKRHGHGVYWWAN |
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MORN | n1180.AA | MORN | 755-776 | 27 | 0.024091 | 6.48 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 755-776 Range on HMM: 1-22/22 Sequence Identity: 27% (6 aa) DYFVGQFINNQANGNGNYMYED | |.. |.. |.| |.. . DRYEGEWHNGKRHGHGVYWWAN |
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MORN | n1180.AA | MORN | 757-776 | 30 | 0.172354 | 10.17 | Pfam | 1-20 (23) | Show / Hide |
Range on Protein: 757-776 Range on HMM: 1-20/23 Sequence Identity: 30% (6 aa) FVGQFINNQANGNGNYMYED . |.. |.. .|.| | . | YEGEWKNGKMHGHGVYTWPD |