Gene n1177 (Tetrahymena)

n1177

Species: Tetrahymena
Alias: 1177, n759.m1174, n1177
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-C6

Sequence

Name Sequence Type Origin Length Description Download
n1177.AA Protein None 79 None Fasta, JSON
n1177.NA RNA None 237 None Fasta, JSON
n1177.kin_dom Protein Kinase Domain None 71 None Fasta, JSON

Protein domain

Protein domains of n1177.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1177.AA Ciliate-C6 1-79 62 5.9e-43 149.02 In-house 121-202 (306) Show / Hide 
Range on Protein: 1-79
Range on HMM: 121-202/306
Sequence Identity: 62% (51 aa)

NIINNLKKSEIYEESEIVKFLSQIGKTLAIIYVEERIAHRDIKPSNILIIDN--NYYLSDFGCAENLFDSEGAKYN-LVMGT
||    .|.| ..|.|||.|..|||||||.||.|..|||||||||||||.|.  ||||||||||..||.||... | ..|||
NIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLFQSEFTRNNDIHMGT
Kinase n1177.AA Ciliate-E2-Unclassified 2-60 30 9.8e-10 29.96 In-house 125-192 (352) Show / Hide 
Range on Protein: 2-60
Range on HMM: 125-192/352
Sequence Identity: 30% (21 aa)

IINNLKKSEIYEESEIV-----KFLSQIGKTLAIIYVEERIAHRDIKPSNILIIDN----NYYLSDFG
. .|.|...| .| ...     ... || . |  .  .  | ||||||.|||. .|    .  ..|||
LFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFG
Kinase n1177.AA CDK-Unclassified 8-62 34 5.8e-09 25.48 In-house 112-173 (324) Show / Hide 
Range on Protein: 8-62
Range on HMM: 112-173/324
Sequence Identity: 34% (22 aa)

KSEIYEES--EIVKFLSQIGKTLAIIYVEERIAHRDIKPSNILIIDNN------YYLSDFGCA
... |  |  .| .|. |. . .| .  .  | ||||||.||.| .||       .. ||| |
HNNRYNLSMCQIRNFMHQMLEGIAYLH-CNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQA
Kinase n1177.AA Ciliate-E1 36-65 54 7.6e-09 25.39 In-house 129-159 (202) Show / Hide 
Range on Protein: 36-65
Range on HMM: 129-159/202
Sequence Identity: 54% (17 aa)

RIAHRDIKPSNILIID-NNYYLSDFGCAENL
.| ||||||.|||| . .|| ..|||.. .|
NIIHRDIKPQNILINNQGNYVYCDFGISKFL
Kinase n1177.AA Pkinase 6-72 24 1.1e-08 31.76 Pfam 95-169 (293) Show / Hide 
Range on Protein: 6-72
Range on HMM: 95-169/293
Sequence Identity: 24% (19 aa)

LK--KSEIY--EESEIVKFLSQIGKTLAIIYVEERIAHRDIKPSNILII-DNNY----YLSDFGCAEN--LFDSEGAK
..  ..  .  .| |. ... || . |. ..  ..| |||.||.||||  ...      ..|||.|.   .  .. ..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT
Kinase n1177.AA LKB 36-65 51 1.1e-08 21.93 In-house 124-154 (265) Show / Hide 
Range on Protein: 36-65
Range on HMM: 124-154/265
Sequence Identity: 51% (16 aa)

RIAHRDIKPSNILI-IDNNYYLSDFGCAENL
|. |.||||.|.|. .||   ..||| || |
RVVHKDIKPGNLLLTHDNTLKICDFGVAEQL
Kinase n1177.AA NAK 37-60 57 1.2e-08 24.85 In-house 144-171 (299) Show / Hide 
Range on Protein: 37-60
Range on HMM: 144-171/299
Sequence Identity: 57% (16 aa)

IAHRDIKPSNILI----IDNNYYLSDFG
|.|||||. |||.    .|.|| | |||
IIHRDIKIENILLSESHHDGNYKLCDFG
Kinase n1177.AA ULK 33-62 34 1.3e-08 26.33 In-house 147-189 (329) Show / Hide 
Range on Protein: 33-62
Range on HMM: 147-189/329
Sequence Identity: 34% (15 aa)

VEERIAHRDIKPSNILIIDNNYY-------------LSDFGCA
....| ||||||.|||| ... .             ..||| |
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase n1177.AA STE 34-79 34 1.7e-08 26.26 In-house 170-226 (359) Show / Hide 
Range on Protein: 34-79
Range on HMM: 170-226/359
Sequence Identity: 34% (21 aa)

EERIAHRDIKPSNILIIDNNYYLSDFGCAENLFDS--------------EGA-KYNLVMGT
. .| ||||||.|||.      |.|||.. .| ||               .. | | . ||
SHHIIHRDIKPANILL----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGT
Kinase n1177.AA ULK 13-62 31 2.5e-08 25.74 In-house 124-185 (324) Show / Hide 
Range on Protein: 13-62
Range on HMM: 124-185/324
Sequence Identity: 31% (20 aa)

EESEIVKFLSQIGKTLAIIYVEERIAHRDIKPSNILIIDNNYY-------------LSDFGCA
.|.|...|. ||   .  .. .. | ||||||.|||| ... .             ..||| |
SEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase n1177.AA Ciliate-B2 37-60 60 4.5e-08 14.97 In-house 125-149 (197) Show / Hide 
Range on Protein: 37-60
Range on HMM: 125-149/197
Sequence Identity: 60% (15 aa)

IAHRDIKPSNILIIDN-NYYLSDFG
| | ||||.|||.  | || ..|||
ILHLDIKPQNILFMQNGNYVYCDFG