Gene n820 (Tetrahymena)
n820
Species: Tetrahymena
Alias: n820, 210.m00050, 820
External Links:
Annotation:
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of n820.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | n820.AA | Ciliate-E1 | 446-594 | 25 | 2.1e-13 | 40.39 | In-house | 1-163 (202) | Show / Hide |
Range on Protein: 446-594 Range on HMM: 1-163/202 Sequence Identity: 25% (43 aa) INSGGEADIFV-----NIEEQIAFRIIKLDKFDYQNYFLKEQLKELYNIKQFQEEQHVLDLTFSHIIEDKTNNQKYIVHIMQICPTSLNKELT------- | .|.....| |...|.| ||.. .. ||.|..|. .. | |..|. .... .|.. . .. |.. | ||...|. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQN----YICIIIFECCCCSLKDYLQNHNRLEY ------SVSEYSLSQALNVIFTSLHFLIALRQKYIYHSDIKPGNILK--IGDQYKVSDFGSSQVIHFSQ ... | .. || .. ||.|.|. |.|.|||| |||. ..|. .||| |... .| WQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQ |
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Kinase | n820.AA | Ciliate-B2 | 441-590 | 28 | 4.2e-13 | 27.06 | In-house | 2-154 (197) | Show / Hide |
Range on Protein: 441-590 Range on HMM: 2-154/197 Sequence Identity: 28% (46 aa) KLGKYINSGGEADIF----VNI---EEQIAFRIIKLDKFDYQNYFLKEQLKELYNIKQFQEEQHVLDLTFSHIIEDKTNNQKYIVHIMQICPTSLNKELT |.||||.||. |. .. . .||.| |. |. .| .|. .| |. . .| . . |. . . | ||..| || .|| YLCKYINKGGCGFICEGYKKHSIREYQDLAFKIY----FNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQINETID-----VLIMEKCECSLKQELQ ----SVSEYSLSQALNVIFTSLHFLIALRQKYIYHSDIKPGNILKIG-DQYKVSDFGSSQVI . .. ...|| . || .| . | | |||| |||. ..|. .||| | .. KIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIK |
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Kinase | n820.AA | Ciliate-A1 | 554-594 | 34 | 6.5e-10 | 29.86 | In-house | 114-155 (301) | Show / Hide |
Range on Protein: 554-594 Range on HMM: 114-155/301 Sequence Identity: 34% (15 aa) LIALRQKYIYHSDIKPGNILKIG--DQYKVSDFGSSQVIHFSQ .... . | |.|.||.||| |. |..|. |.| |.. ..| YADIHDHNILHRDLKPQNIL-IHFDDKWKICDLGMSKQLEQNQ |
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S_TKc | n820.AA | S_TKc | 440-690 | 14 | 2.1e-07 | -68.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 440-690 Range on HMM: 1-231/231 Sequence Identity: 14% (41 aa) LKLGKYINSGGEADIFVNIE----EQIAFRIIKLDKFDYQNYFLKEQLKELYNIKQFQEEQHVLDLTFSHIIEDKTNNQKYIVHIMQICPT---SLNKEL .... | .|. . . .. .. | ||| . ..|. |. .. | . ... .| |.. .| . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYI TSVSE------YSLSQALNVIFTSLHFLIALRQKYIYHSDIKPGNILKIGDQYKVSDFGSSQVIHFSQPFAQPLACTPYYT-PRRFQNLPFYH---DIYS . .. .| .. . | . .. | | |.|| ||| . |..|||.. .. . ||.| | . .. . |..| KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWS VAKTIEIVLNKINGHQVVKEMLLQQVDKLLKDDENSIKIDCFQLPQEFIDCLIDQCDK-EVD-----EFLQ--------TYL . .. . | . .|..... ..|..| .|..| . . . | || .. CGCILYEMLCGYPPFP-QMQMMFKKIG-----------------SPEAKD-FIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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Kinase | n820.AA | MOK | 562-596 | 45 | 3.8e-07 | 17.9 | In-house | 121-155 (283) | Show / Hide |
Range on Protein: 562-596 Range on HMM: 121-155/283 Sequence Identity: 45% (16 aa) IYHSDIKPGNILKIGDQYKVSDFGSSQVIHFSQPF |.| |.|| ||| | |..|||| . ||. IFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPY |
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Kinase | n820.AA | Ciliate-E3 | 554-587 | 46 | 4.5e-07 | 18.41 | In-house | 116-153 (202) | Show / Hide |
Range on Protein: 554-587 Range on HMM: 116-153/202 Sequence Identity: 46% (18 aa) LIALRQKYIYHSDIKPGNILKIGDQY-----KVSDFGSS .||. .| | |||||| ||| .. . | .||| | MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGES |
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Kinase | n820.AA | Ciliate-C6 | 562-594 | 48 | 2e-06 | 18.77 | In-house | 157-191 (306) | Show / Hide |
Range on Protein: 562-594 Range on HMM: 157-191/306 Sequence Identity: 48% (17 aa) IYHSDIKPGNILKIGD--QYKVSDFGSSQVIHFSQ | | |||| ||| . | |. |||| .| . |. IAHRDIKPSNILIMDDENNYYLSDFGCAQQLFQSE |
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Kinase | n820.AA | ULK | 554-606 | 26 | 3e-06 | 18.21 | In-house | 139-213 (324) | Show / Hide |
Range on Protein: 554-606 Range on HMM: 139-213/324 Sequence Identity: 26% (20 aa) LIALRQKYIYHSDIKPGNILKIGDQ-------------YKVSDFGSSQVIH---FSQPFAQPLA------CTPYY . .|... | | |||| ||| .| .|..||| .... ..| | . .||.| FKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLY |
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Kinase | n820.AA | ULK | 554-606 | 25 | 4e-06 | 17.38 | In-house | 143-217 (329) | Show / Hide |
Range on Protein: 554-606 Range on HMM: 143-217/329 Sequence Identity: 25% (19 aa) LIALRQKYIYHSDIKPGNILKIGDQ-------------YKVSDFGSSQVIHFS---QPFAQPLA------CTPYY . .|... | | |||| ||| .| .|..||| .... . | .. .||.| FKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLY |
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Kinase | n820.AA | ELM | 562-587 | 42 | 0.000126 | 11.58 | In-house | 168-195 (346) | Show / Hide |
Range on Protein: 562-587 Range on HMM: 168-195/346 Sequence Identity: 42% (12 aa) IYHSDIKPGNILKIGDQ--YKVSDFGSS . | |||| |.| .. |.||||.. CIHRDIKPSNLLISENGKTVKISDFGVC |
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Kinase | n820.AA | LKB | 562-585 | 48 | 0.000211 | 9.04 | In-house | 125-149 (265) | Show / Hide |
Range on Protein: 562-585 Range on HMM: 125-149/265 Sequence Identity: 48% (12 aa) IYHSDIKPGNIL-KIGDQYKVSDFG . | ||||||.| .. |..||| VVHKDIKPGNLLLTHDNTLKICDFG |
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Kinase | n820.AA | Pkinase | 562-606 | 30 | 0.000463 | 15.44 | Pfam | 129-177 (293) | Show / Hide |
Range on Protein: 562-606 Range on HMM: 129-177/293 Sequence Identity: 30% (16 aa) IYHSDIKPGNILKIG--DQY----KVSDFGSSQVI-HFSQPFAQPLACTPYY | | |.|| ||| | .. |..|||.. .. . ... .. ...||.| IIHRDLKPENIL-IDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY |
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LRR_RI | n820.AA | LRR_RI | 1006-1033 | 28 | 0.002292 | 17.17 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1006-1033 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NIKYLTLDLRQNQIGDAGAQNIVKSLAK | . ..|.|..| .||.|.. . ..|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1079-1107 | 20 | 0.279124 | 2.45 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1079-1107 Range on HMM: 1-28/28 Sequence Identity: 20% (6 aa) LSSLQTKFYQLGNNIGDQGVQSIAKAIQQ ..||.. . .|..|| |.. ....... NCSLRE-LWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1140-1167 | 32 | 0.05168 | 7.62 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1140-1167 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NLRQLHLDLSSNNIGDETAQVFTKTFKK | . . |.||.|..||| .... .. | NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1170-1197 | 25 | 0.129678 | 4.8 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1170-1197 Range on HMM: 1-28/28 Sequence Identity: 25% (7 aa) NITQLSIYLMNNGISNQGAQSISDALKY | . . ..| ||.. |.. .. .|| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1200-1227 | 21 | 0.100217 | 5.59 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1200-1227 Range on HMM: 1-28/28 Sequence Identity: 21% (6 aa) NVTQLNLSLAYNKIDHIGAQKIAKVFEN | . . |.|..||. |.. .... . NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1258-1287 | 23 | 0.155163 | 4.25 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1258-1287 Range on HMM: 1-28/28 Sequence Identity: 23% (7 aa) SQNITRLDLIIGSNYITHEGASIIAETLEK .... .|.| ..| .. ||. ..|.|. NCSLRELWL--SNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1230-1257 | 28 | 0.198821 | 3.49 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1230-1257 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) KISQLCLDLRINKIGNQGIKEIANSLNK . | . |.|. ||.| |.......| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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Kinase | n820.AA | MOK | 1534-1559 | 34 | 0.143131 | 0.11 | In-house | 1-26 (283) | Show / Hide |
Range on Protein: 1534-1559 Range on HMM: 1-26/283 Sequence Identity: 34% (9 aa) YNEIGKEGAQQISNALQMQYCKNFNF | ||| | .|. ..|| .. |. YKAIGKIGEGTFSEVMKMQSLRDGNY |
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LRR_RI | n820.AA | LRR_RI | 1522-1551 | 30 | 0.150183 | 4.35 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1522-1551 Range on HMM: 1-28/28 Sequence Identity: 30% (9 aa) CQDLTQLNLYFHYNEIGKEGAQQISNALQM . | |.| .| .| ||..|....|. NCSLRELWLS--NNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1583-1610 | 17 | 0.089403 | 5.94 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1583-1610 Range on HMM: 1-28/28 Sequence Identity: 17% (5 aa) NITKLNIDIRSNEISDKGVQSIANSLPK | . . .....| . |.|.. ....| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1613-1640 | 35 | 3.1e-05 | 24.62 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1613-1640 Range on HMM: 1-28/28 Sequence Identity: 35% (10 aa) NITLLNLDLSSNKIGDKGIQSVSTAIQQ | .|. |.||.||.||.|.. . .... NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1684-1713 | 36 | 0.004902 | 14.84 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1684-1713 Range on HMM: 1-28/28 Sequence Identity: 36% (11 aa) NSNIQQLKLNLSQNKIGDDGIQNISECLIK |.... .|.||.||.||.|.. ..|.| NCSLR--ELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1716-1743 | 25 | 0.020798 | 10.41 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1716-1743 Range on HMM: 1-28/28 Sequence Identity: 25% (7 aa) NITHLCLNLQENQISDCGAQSIANALEK | . . |.|. | . |.|.. ....|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1746-1772 | 28 | 0.142081 | 4.52 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1746-1772 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NITQLNLDL-GNSITDEGAKIISNALEK | . . |.| .| ..|||.. ....|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
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LRR_RI | n820.AA | LRR_RI | 1775-1802 | 32 | 2e-06 | 28.63 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1775-1802 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) NVTLLNLNLNENQFGDDGAQSIANALQK | .|. |.|. | .||.|.. ....|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |