Gene n184 (Tetrahymena)
n184
Species: Tetrahymena
Alias: n184, 3824.m02848, 184
External Links:
Annotation:
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of n184.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | n184.AA | Ciliate-A5 | 201-274 | 28 | 1.1e-12 | 40.39 | In-house | 200-275 (275) | Show / Hide |
Range on Protein: 201-274 Range on HMM: 200-275/275 Sequence Identity: 28% (22 aa) DIFTLGLSLLEMATLEKSSELFR-VDIYQINVKKFDQRLALIKQ-RYSDKLVNIIKQMLTMDPRHRPSCESLIGQI |.|.||. .|||.|... . . . || . . | |. .||. ..|.||||| .. ||. . . . DVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | n184.AA | NEK | 241-276 | 39 | 3.3e-09 | 28.97 | In-house | 249-286 (286) | Show / Hide |
Range on Protein: 241-276 Range on HMM: 249-286/286 Sequence Identity: 39% (15 aa) IKQR--YSDKLVNIIKQMLTMDPRHRPSCESLIGQIRT | .. ||..| |.| |||. || .||||.... . IPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | n184.AA | NEK2 | 244-276 | 36 | 4.8e-09 | 26.47 | In-house | 287-319 (319) | Show / Hide |
Range on Protein: 244-276 Range on HMM: 287-319/319 Sequence Identity: 36% (12 aa) RYSDKLVNIIKQMLTMDPRHRPSCESLIGQIRT .||. | || |. |..|||| | ...... QYSRHLNEIIHFMINVDHYHRPSIEEILQHPQI |
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| S_TKc | n184.AA | S_TKc | 15-276 | 17 | 2e-08 | -53.46 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 15-276 Range on HMM: 1-231/231 Sequence Identity: 17% (51 aa) LKQEKNLK--AFGRVGICETKGTKRPL----LACEAKYSEQEPQYYLNLKHPNLVSPLVYDAHFKEFLNLNAQGVTFYFDYLDI---SLEDIIQSRKV-- . . . |||.| | |.|.| . . ..| | . .|||.| ||. . . . ..|.| .| |.|..|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVK--LYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHG RNSIFPEQEILNVGLAVLTTLQFLKQHNIEGGNIEPATIFYDKGQIKI--------YNNQLILGRLACYSMIVNYFQRNPLPSPEVLYSAKKRETELVEK ... ||| .. . .. |... .|.| . |. |. |. .||| . ..... . . .|||| . LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCGTPWYM----APEVL------------G YRY-ETDIFTLGLSLLEMAT----LEKSSELFRVDIYQINVKKFDQRLALIKQRYSDKLVNIIKQMLTMDPRHRPSCESLIG-------QIRT | . . |. .| | ||.. . .... . |. . ..|...|..||..||.. . YGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | n184.AA | NAK | 243-274 | 37 | 1.2e-07 | 21.51 | In-house | 268-299 (299) | Show / Hide |
Range on Protein: 243-274 Range on HMM: 268-299/299 Sequence Identity: 37% (12 aa) QRYSDKLVNIIKQMLTMDPRHRPSCESLIGQI .|||... ..|. ||| ||..||. . .. |. SRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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| Kinase | n184.AA | NAK-Unclassified | 244-276 | 39 | 2.2e-07 | 21.55 | In-house | 373-405 (405) | Show / Hide |
Range on Protein: 244-276 Range on HMM: 373-405/405 Sequence Identity: 39% (13 aa) RYSDKLVNIIKQMLTMDPRHRPSCESLIGQIRT .||..| | || || ||..||. .. .| NYSNQLHNLIKIMLNEDPIQRPNIYQVLNHICQ |
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| Kinase | n184.AA | Ciliate-E1 | 79-203 | 14 | 3.6e-07 | 19.86 | In-house | 68-202 (202) | Show / Hide |
Range on Protein: 79-203 Range on HMM: 68-202/202 Sequence Identity: 14% (20 aa) NAQGVTFYFDYLDISLEDIIQ---------SRKVRNSIFPEQEILNVGLAVLTTLQFLKQHNIEGGNIEPATIFYDKGQIKIYNNQLILGRLACYSMIVN .... ...|.... ||.| .| . . . | .|.... . |. |.|.|| ..| |. | ... . .... .... ... . . QNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQ YFQRNPLPSPEVLYSAKKRET--ELVEKYRYETDIF . ... . . . . | . .|. |..||. CQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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| Kinase | n184.AA | NEK4 | 196-274 | 31 | 2e-06 | 19.21 | In-house | 179-257 (257) | Show / Hide |
Range on Protein: 196-274 Range on HMM: 179-257/257 Sequence Identity: 31% (26 aa) YRYETDIFTLGLSLLEMATLEKSSELFRVD--IYQINVKKFDQRLALIKQRYSDKLVNIIKQMLTMDPRHRPSCESLIGQ--I | | || || . ||.|| . . |||| . .. . . || | |...||| | ||| ... . | YDYKSDIWSLGCCVYEMITLKHAFDAKDMNSLIYQI----IQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI |
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| Kinase | n184.AA | SLK | 196-276 | 23 | 3e-06 | 16.77 | In-house | 179-259 (259) | Show / Hide |
Range on Protein: 196-276 Range on HMM: 179-259/259 Sequence Identity: 23% (19 aa) YRYETDIFTLGLSLLEMATLEKSSELFRVDIYQINVKKFDQRLALIKQRYSDKLVNIIKQMLTMDPRHRPSCESLIGQIRT | | .||. ||. |.||| .| . . . ..| . . ..| . ...|. | ||. |.. . |. YDYKADIWSLGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV |
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| Kinase | n184.AA | WEE | 241-276 | 30 | 3e-06 | 17.31 | In-house | 262-297 (297) | Show / Hide |
Range on Protein: 241-276 Range on HMM: 262-297/297 Sequence Identity: 30% (11 aa) IKQRYSDKLVNIIKQMLTMDPRHRPSCESLIGQIRT ... .|. | ..||.|. ||. ||.|..| .. FDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL |
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| Kinase | n184.AA | Dicty3 | 246-271 | 34 | 4e-06 | 16.06 | In-house | 326-351 (351) | Show / Hide |
Range on Protein: 246-271 Range on HMM: 326-351/351 Sequence Identity: 34% (9 aa) SDKLVNIIKQMLTMDPRHRPSCESLI |....|.|.. .. || ||.. ..|| SNFCKNFIQHCWQIDPNHRWDMHELI |
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| Kinase | n184.AA | Ciliate-A5 | 48-143 | 29 | 0.000118 | 12.16 | In-house | 34-131 (275) | Show / Hide |
Range on Protein: 48-143 Range on HMM: 34-131/275 Sequence Identity: 29% (29 aa) EQEPQYYLNLKHPNLVSPLVYDAHFKEFLNLNAQGVTFYFDYLDISLEDIIQSRKVRN--SIFPEQEILNVGLAVLTTLQFLKQHNIEGGNIEPATIF .|. . .|.|||.| . ...| || . . | .|. | |..|| .| || .. |||. .. . .|.| ||. |.| |..|. QQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNIC |
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| Kinase | n184.AA | WEE | 201-214 | 50 | 0.040219 | 3.0 | In-house | 218-231 (297) | Show / Hide |
Range on Protein: 201-214 Range on HMM: 218-231/297 Sequence Identity: 50% (7 aa) DIFTLGLSLLEMAT ||| ||. ..|.|. DIFSLGITIYELAC |
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| Kinase | n184.AA | WEE | 93-127 | 24 | 0.27472 | 0.16 | In-house | 91-127 (297) | Show / Hide |
Range on Protein: 93-127 Range on HMM: 91-127/297 Sequence Identity: 24% (9 aa) S--LEDIIQSRKVRNSIFPEQEILNVGLAVLTTLQFL | | ..||. . | ..||..| .. . ....|... SNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHI |
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