n1171

Species: Tetrahymena
Alias: n1171, n.8814, 1171
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-B3

Sequence

Name Sequence Type Origin Length Description Download
n1171.AA Protein None 1152 None Fasta, JSON
n1171.NA RNA None 1911 None Fasta, JSON
n1171.kin_dom Protein Kinase Domain None 176 None Fasta, JSON

Protein domain

Protein domains of n1171.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1171.AA Ciliate-B3 98-166 76 9.1e-44 151.72 In-house 1-69 (69) Show / Hide
Range on Protein: 98-166
Range on HMM: 1-69/69
Sequence Identity: 76% (53 aa)

LALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKNCKSREICGTLSY
.|||.|.|||||||||||||.||||||..|||...||.||||||||||||.||.|.||||..|||||.|
FALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY

Kinase n1171.AA CAMK 99-169 23 1e-15 46.44 In-house 181-289 (425) Show / Hide
Range on Protein: 99-169
Range on HMM: 181-289/425
Sequence Identity: 23% (26 aa)

ALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQD-------------QENYKVIIIDFGHYQRACK------------------------NCKSREIC
| ..|.|... .. .|..|..|.|.|.||||||. .             ..|... |||||  ..  .                        . | .. |
ARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFC

GTLSYNP-P
||..| . |
GTPEYMAAP

Kinase n1171.AA MARK 98-169 40 1.2e-15 47.81 In-house 105-174 (262) Show / Hide
Range on Protein: 98-169
Range on HMM: 105-174/262
Sequence Identity: 40% (29 aa)

LALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKNCKSREICGTLSYNPP
.| ..|.|.|. .. .|.||..|.|||.||||.| . . | |  |||||   .   ..|  . |||..| .|
EARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIK--IIDFGFSICIPPGQKLNTFCGTPPYMAP

Kinase n1171.AA Ciliate-E2-Unclassified 99-169 30 1.1e-14 47.39 In-house 140-235 (352) Show / Hide
Range on Protein: 99-169
Range on HMM: 140-235/352
Sequence Identity: 30% (30 aa)

AL-----KLFKQVVEKIKILHEKN-VCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKN----------------CKSREICGTLSYN----PP
|.     ..|.|... .. ||.|| ..| |||.||||.||. . ||.. |||||   .  .|                ...  .|||..|     .|
AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAP

Kinase n1171.AA Ciliate-E2 99-207 22 3e-14 45.31 In-house 147-291 (365) Show / Hide
Range on Protein: 99-207
Range on HMM: 147-291/365
Sequence Identity: 22% (36 aa)

ALKLFKQVVE---------------KIKILHEKN-VCHCDIKLENILLDNQDQENYKVIIIDFGHYQ------------RACKNCKSRE-----------
.....||...                .. ||.|| ..| |||.||||.         . |||||  .            . ||...              
IKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD

----------ICGTLSYNPPKIIEDFE---QFLLSGKQIEEYSPQELDVYQLGMLLFHILF
          ||||. | .| |..  .   |      | ...   . |.. ||..|.  ||
QIIQQNMFNTICGTPGYMAPEILNGKKYDNQ------QKQKGYDYKCDIWSLGVILYEMLF

Kinase n1171.AA Ciliate-E9 103-207 30 6.2e-13 37.31 In-house 117-220 (298) Show / Hide
Range on Protein: 103-207
Range on HMM: 117-220/298
Sequence Identity: 30% (35 aa)

FKQVVEKIKILHEKN-VCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKN---------CKSREICGTLSYNPPKIIEDFEQFLLSGKQIEEYSPQE
|||... |  .| .  .|| |.|.||.|.|    .||   |.|||   .             |.. |  ||  |||| .    .|.     |  .|. | 
FKQLIDSIEYMHQYQNICHRDLKPENMLID----KNYNMKICDFGMSAQCRNDKTQVIGNLQCQPKENHGTNQYNPPNNQQ--QQY-----QGIKYNGQK

LDVYQLGMLLFHILF
 |.. .| .|| ...
FDIFSAGCILFMMVM

Kinase n1171.AA DAPK 99-163 36 7.2e-13 31.47 In-house 105-169 (264) Show / Hide
Range on Protein: 99-163
Range on HMM: 105-169/264
Sequence Identity: 36% (24 aa)

ALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKNCKSREICGT
| .. ||. | .. || .|.|| |.| .||.| .   .. .. |||||   . |. .  |.| ||
ATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGT

Kinase n1171.AA MSK 103-206 27 3.8e-12 37.37 In-house 107-204 (277) Show / Hide
Range on Protein: 103-206
Range on HMM: 107-204/277
Sequence Identity: 27% (29 aa)

FKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFG--HYQRACKNCKSREICGTLSYNPPKIIEDFEQFLLSGKQIEEYSPQELDVYQLGM
. ..|  .. .|.| . | |.|.||||.|... .| .| .||||   .  . .. .    |.|| | .| .... .      .| ..|...  |.. || 
MRELVMAVDHMHQKGIIHRDLKPENILFDDEE-DNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGY------AQDGGYDEA-CDWWSLGV

LLFHIL
.|.  |
ILYTML

Kinase n1171.AA Ciliate-E8 105-148 43 1.1e-11 32.79 In-house 97-138 (138) Show / Hide
Range on Protein: 105-148
Range on HMM: 97-138/138
Sequence Identity: 43% (19 aa)

QVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGHY
|. . . .||  |. |||.||.|||.   |  . |  |||||  
QIMDAFCYLHNNNIIHCDFKLNNILVQRNDDTKIK--IIDFGFS

Kinase n1171.AA CAMKL 99-146 42 1.5e-11 32.98 In-house 129-174 (297) Show / Hide
Range on Protein: 99-146
Range on HMM: 129-174/297
Sequence Identity: 42% (21 aa)

ALKLFKQVVEKIKILHEKNVCHCDIKLENILLD-NQDQENYKVIIIDFG
| ..|.|.|. .. .|.....| |||.|||||| |...   .. |||||
ARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFG

Kinase n1171.AA Pkinase 99-169 29 6.5e-10 36.14 Pfam 110-180 (293) Show / Hide
Range on Protein: 99-169
Range on HMM: 110-180/293
Sequence Identity: 29% (22 aa)

ALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGH---YQRACKNCKSREICGTLSYNPP
. . ..|... .. .|.....|.|.|.||||.||... . .| |.|||    ..   .|     .|||. | .|
CKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAP

S_TKc n1171.AA S_TKc 3-273 16 8.1e-10 -32.95 SMART 1-231 (231) Show / Hide
Range on Protein: 3-273
Range on HMM: 1-231/231
Sequence Identity: 16% (50 aa)

EDKAEFYGGQARGEVFKCEARQ--NVYFRKIFEFENDYVREKQFYEKVLKNEIAKEQQSSFLELILFDDSKKELIFPFINS---QLVELVSNQKGI----
 .. .  |  | |.|.||  .    ..  ||    ..  || |  .|       .      |  .  | ..  ... ...     | ..  ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-KCRYLALKLFKQVVEKIKILHEKNVCHCDIKLENILLDNQDQENYKVIIIDFGHYQRACKNCKSREICGTLSYNPPKIIEDFEQFLLSGKQIEEYSPQE
      | ....|... .. .|.....|.|.| ||||||.       . |.|||   .       . .|||. | .| ..               |.. .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL--------------GYGKCK

LDVYQLG-----MLLFHILFYIRLTTGIKKVAQLKKRHLFKRAILSSYREAYKKELDLDEDIFDLIYKILSGEIK---DINQIQQ-------HDIY
 |.. .|     ||    .|.  . . .||.                           ...  |.| |.|  . .    . .. |       |   
CDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF