Gene tlk (Fruit Fly)

tlk

Species: Fruit Fly
Alias: tlk, CG2829
External Links: Flybase Link
Annotation:

Classification

Group: Other
Family: TLK

Sequence

Name Sequence Type Origin Length Description Download
tlk.AA Protein None 1156 None Fasta, JSON
tlk.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of tlk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase tlk.AA TLK 903-1156 80 5.3e-227 760.42 In-house 1-259 (285) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-259/285
Sequence Identity: 80% (209 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKT
|.||.||||||||||.|||||.|.||||||.|||||.|||.|||||||||.|||.|||.|||.|.|||||.||||.||||||||||.|.|||||||||||
YQLLHLLGKGGFSEVYKAFDLHEFRYVACKIHQLNKNWKEEKKANYIKHACREYKIHKELDHCRIVKLYDYFEIDNNSFCTVLEYCEGNDLDFYLKQHKT

IPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGK-----NPP
.||.|||.||||.|..||||||||||.|||||||.||....||.|||||||||||||.||||.|..||||.|||||||||||||||||||||     |||
MPEKEARCIIMQIVCCLKYLNEIKPPIIHYDLKPQNIIFHKGNTCGEIKITDFGLSKIMDDEQYRHDHGMELTSQGAGTYWYLPPECFVVGKCEEFENPP

KISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAK
|||.|||||||||||||||||.||||||.||..|||.|||||||||||..||.||||.|
KISCKVDVWSVGVIFYQCLYGQKPFGHNMSQQQILEQNTILKATEVQFPSKPQVSNECK
Kinase tlk.AA S_TKc 903-1146 29 3.4e-56 193.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 903-1146
Range on HMM: 1-231/231
Sequence Identity: 29% (83 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDG--HDLDFYLKQH
| .| ..|||.|..|.|. . | .|.||.|.                .|..|| .|.|  .|| .|||||||.   .... |.|||||   ||  |.|..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR

KT------IPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGK
..      .|| .||... |...||.|. .    .|| |||| ||||.|     .|||.||||....              .   || ||..|| .    
GRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL----

NPPKISS-KVDVWSVGVIFYQCLYGKKPFGHNQSQ--------------ATILEEN-----TILKATE-------VQFS
   . .  |.|.||.|.|.| .|.|. ||  .. .                .|. .     |. .| .        .. 
---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase tlk.AA ULK 903-1156 30 1.2e-53 184.57 In-house 1-298 (324) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-298/324
Sequence Identity: 30% (93 aa)

YLLLMLLGKGGFS-EVHKAFDLKE---QRYVACKVHQLNKDWKEDKKA--NYIKHALR-EYNIHKALD---HPR--VVKLYDVFEIDA-NSFCTVLEYCD
| |   |||| |   |.|... |    . |||||. ...|  |  ...  .|..  |. | .| | |.   ||   .|||||.|| .  | .. ..|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GHDLDFYLKQHKT---------IPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVC---------GEIKITDFGLSKVMDDENYNPDHG
| ||. |.|..|.         ..| ||.....| ....|.|.. .  .|| |.|| |||...|.           | .||.|||..|. |..| . .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHN--IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

MDLTSQGA---GTYWYLPPECFVVGKN--PPKIS-SKVDVWSVGVIFYQCLYGKKPFGHNQSQATI-----LEEN-----TILKATEVQFS---NKPTVS
. .  .     ||  |  |.  .. ..    . . .|.|.||.|.|||..|||| ||  .  . ..     | .|     .. | . .||    . | .|
QTCVNE-KRIKGTPLYMAPQ--ILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

NEAK
.| |
PECK
Kinase tlk.AA ULK 903-1156 29 4.7e-53 182.57 In-house 1-303 (329) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-303/329
Sequence Identity: 29% (92 aa)

YLLLMLLGKGGFSEVHKAFDLKE----QRYVACKVHQLNKDWKEDKKA--NYIKHALR-EYNIHKALD--------HPRVVKLYDVFEIDA-NSFCTVLE
| |   |||| |  |.|... |     . .||||. ...|  .. . .  .|..  |. |  | | |.        || .|||||.|| .  | .  ..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCDGHDLDFYLKQHKT----------IPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVC---------GEIKITDFGLSKVMDDENYN
||.| ||. |.|..|.          ..| ||.....| ....|.|.. .  .|| |.|| |||...|.           | .||.|||..|..|..| .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHN--IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

PDHGMDLTSQGA---GTYWYLPPECFVVGKN--PPKIS-SKVDVWSVGVIFYQCLYGKKPFGHNQSQATI------LEENTILKA-----TEVQFS---N
 .  |  . .     ||  |  |.  .. ..    . . .|.|.||.|.|||..|||| ||  .  . ..      | .|.   .     .  ||    |
QQMMMTCVNE-KRLCGTPLYMAPQ--ILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

KPTVSNEAK
.|..|.| |
DPQISPECK
Kinase tlk.AA Ciliate-E2 903-1156 23 5.4e-51 173.29 In-house 1-334 (365) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-334/365
Sequence Identity: 23% (84 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVA----------------CKVHQLNKDWKEDKKANYIKHALREYN-------------IHKALDHPRVVKLYDV
| .. ..|.|.|. | |. . |.|. .|                .|. . ..  .. .. ..||  .....             | . |.|| ..|.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE-IDANSFCTVLEYCDGHDLDFYLKQHKTIP-----------EREARSIIMQVVS---------------ALKYLNEIKPPVIHYDLKPGNILLTEGNV
|. .| |..  |.|||.| ||  |.|..|.             |.|.. |. |...               ||.|| . .. .|| |.|| |||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

CGEIKITDFGLSKVMDDE-----------NYNPDHGMDLTSQG--------------AGTYWYLPPECFVVGK-----NPPKISSKVDVWSVGVIFYQCL
   |||.||||||  ||.           .|   .... ...|              .||. |..|| .  .|     .    . |.|.||.|||.|..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

YGKKPFGHNQSQATILEENTILKATEVQFS----------------NKPTVSNEAK
.|| ||              . |  ...|.                ..  .|.|.|
FGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECK
Kinase tlk.AA Pkinase 903-1156 27 6e-50 177.04 Pfam 1-267 (293) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-267/293
Sequence Identity: 27% (78 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGH----DLDFYLK
| ..  .|.|.|..| |. . .... ||.|.  ..|. .|... ....  |.|  |.| |.|| .|.|||.||   .. . |.|||.|     ||  |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI--IKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

--QHKTI--PEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLT-EGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVG
  .|...  .|.|..... |....|.|. .    .|| |||| |||.  .|...  .||.||||.|..|            ..  .||.||..||     
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIR--

KNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQ----SQATILEENTILKATEVQFSNKPTVS-------------------NEAK
   .....|||.||.|.|.|. | |. ||  ..    . .. ..     . ... |.   . |                    |.|
-GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK
Kinase tlk.AA CAMK 908-1156 20 1.2e-47 151.17 In-house 1-399 (425) Show / Hide 
Range on Protein: 908-1156
Range on HMM: 1-399/425
Sequence Identity: 20% (82 aa)

LLGKGGFSEVHKAFDLKEQ------------RYVACKV--------------------HQLNKDWKEDK-KANYIKHALREYNIHKA-------LDHPRV
 ||.|.|..|..... . .            . ||.|.                       .... ... ...  |  .||..|.|        |||| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYDVFE------------IDAN-------SFCTVL---EYCDGH----DLDFYLKQH---------------KTIPEREARSIIMQVVSALKYLNEIK
.|||.|.|               .        .. |.   |||.|     ||  |...|               . ..||||| .. |..||..|. . .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PPVIHYDLKPGNILLTEGNVC--------------GEIKITDFGLSKVMDDENYN-----PDHGMDLTSQ-------------GAGTYWYLP-PECFVV-
  ..| |||| ||||.. |                . |||.|||.....|. . |     ...|  . ..               ||  | . || .   
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

---------GKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATI-------LEENTILKATEVQFS-NKPT---------------VSNE------
           . | .. |.|.||.||| | .| |. || .   . ..        ....  | .. ...   |                .|.|      
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

--AK
  .|
QECK
Kinase tlk.AA Ciliate-E2-Unclassified 903-1156 23 6.2e-47 160.83 In-house 1-322 (352) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-322/352
Sequence Identity: 23% (76 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYV-----ACKVHQLNKDWKEDKKANYIKHALREYNIH---------------KALDHPRVVKLYDVFEIDANSFC
| ..  .|.|||..|.|. . |.. ..     ..|... ..  .. |. ...  .... |.                . ..|| .||....|. . | ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN-IY

TVLEYCDGHDLDFYLKQHKT-----------------IPEREAR-----SIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKV
 |.|||.| || .|.|. |.                 ..|..|.      .. |....|.|| . .  .||.|.|| |||.....  ..|||.|||.|| 
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

MDDENYNPDH---------GMDLTSQGAGTYWYL----PPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQA------------TILEEN
 .. |..  .           ..... .||. |.    .||..   ..  . . |.|.||.|||.|..|.|. ||. |..              ....  
YQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

TILKATEVQFSNKP------TVSNEAK
 . |. ..||.. |      ..|.|||
QNIKQKNIQFPKFPWQQIPKHWSPEAK
Kinase tlk.AA AGC 903-1156 21 8.9e-47 117.82 In-house 1-359 (395) Show / Hide 
Range on Protein: 903-1156
Range on HMM: 1-359/395
Sequence Identity: 21% (82 aa)

YLLLMLLGKGGFSEVHKAFDL------KEQRYVACKVHQLNKD-WKEDKKANYIKHALRE------------YNIHKALD----------HPRVVK-LYD
. .| ..|||.|..|. . .         ..| |.||  |.|. .  .|| | ..|...|             || . ..          || .|| |. 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKV--LKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY

VFEIDANS-FCTVLEY---------CDGH-DLDFYLK---QHKTIPEREARSIIMQ-------VVSALKYLNE-IKPPVIHYD-LKPGNILLTEGNVCGE
 |. . ..  . |.||         | |  .| ..|.   . .. .| .|| .. .       .|.|| || .  .  .|| | ||| ||||.|    | 
SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMG--IIHRDYLKPENILLDED---GH

IKITDFGLSKVMDDEN--------------------------------------------YNPDHGMDLTSQGAG--TYWYLPPECFVVGKNPPKISSKV
||.|||||.|.. ...                                            ..  ...|.|.   |  |  |..|| .         .  .
IKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL--------YGKAC

DVWS--VGVIFYQCLYGKKPFGHNQ---------SQATILEENTILK---ATEVQFSNK--------PTVSNEAK
| ||  .|...|. |.|. || ...         ... . .   . .     .|.| ..        . .|.|||
DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAK
Kinase tlk.AA CMGC 903-1113 21 7.3e-39 124.7 In-house 1-326 (513) Show / Hide 
Range on Protein: 903-1113
Range on HMM: 1-326/513
Sequence Identity: 21% (70 aa)

YLLLMLLGKGGFSEVHKAFD--------------LKEQRYVACKVHQLNKDWKEDK----KANYIKHALREYNIHKAL-----------------DHPRV
|  .  .|.| ...| |..|               . ...|| |   ....  . |    | .  . ||||  | | |                 .|. .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VKLYDVFEIDA----------------NSFCTVLEYCDGHDLDFYLKQHK---------TIPERE------------ARSII------MQVVSALK--YL
|||||.|  .                 |... | ||.| |||  |.|...           .| .             ....       |.  .||  |.
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMD-HDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

NEIKPPVIHYDLKPGNILLTEGNVC-----------------GEIKITDFGLSKVMDDENY----------------NPDHGMDLTSQGAGTYWYLPPEC
   .  .|| |||| |||... . .                 |..|| ||||..  ...                  . .... .|.. . | || .|| 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVV-TRWYRAPEI

FVVGKNP------PKISSKVDVWSVGVIFY
 .  |.        . ....|.|||| ||.
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFA
Kinase tlk.AA TKL 909-1122 20 5e-37 129.34 In-house 1-289 (364) Show / Hide 
Range on Protein: 909-1122
Range on HMM: 1-289/364
Sequence Identity: 20% (60 aa)

LGKGGFSEVHKAFDLKEQ--------RYVACKVHQLNKDWKEDKKAN--------------------YIKHALREYNIHKALDHPRVVKLYD-VFEIDAN
.|.|||.||.|.    .         . || |.   . | ...|. .                    . ..  .| .... |.|| .|...  ..... .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

S-----------FCTVLEYCDGHD-LDFYLKQHKTIPEREARSIIMQVVSALKYLNEIK------PPVIHYDLKPGNILLTE-GNVC----------GEI
            .| | |||.| . |....            ...... ... ||   .      ||.|| |||. |||. | ....          . .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KITDFGLSKVMDDENYNPDHGMD------------LTSQGAGTYWYLPPECFVVGKNPP------------KISSKVDVWSVGVIFYQCLYGKKPF
||.|||||..|. .. . | ...             |.   ||. ...||..    | .            . | |.||.| |.... .| ...|.
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY
Kinase tlk.AA PLK-Unclassified 903-1058 33 6.5e-31 109.02 In-house 1-153 (264) Show / Hide 
Range on Protein: 903-1058
Range on HMM: 1-153/264
Sequence Identity: 33% (55 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQH--
|  . .||||||. . .. ...  .  | |.    |   . ..|   .  . |  ||| |.|. .|| ...|| . |    .|||| ...|  |.| .  
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKI--IPKSSLTKNRAR--QKLISEIKIHKSLHHKNIVKFEHCFEDHENVYI-LLEYCPNGTLMEYIKRRNF

-----KTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLS
     | . | |.... .|.| |||||   .  .|| |||.|||.|.. .   |.|| ||||.
QLFEKKRLTEYEVKCYTYQIVQALKYLHQNR--IIHRDLKLGNIFLNDNM---EVKICDFGLA
Kinase tlk.AA TyrKc 903-1145 22 6.8e-12 -30.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 903-1145
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKAL--DHPRVVKLYDVFEIDA------NSFCTVLEYCDGHDLD
  |.  || | | ||.|.      . || |. . ..          ..  .|| .| . |  .|| .|.|| |   .          . |.||... ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

FYLKQHKT-IPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDE-------NYNPD----HGMDLTSQGAGTY
 ||. |.  .. ..  |.  |. .   || .   ..|| ||   |.|..|..    .||.|||||.  .|.        |       .| ..       .
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM-----LPI

WYLPPECFVVGKNPPKISSKVDVWSVGVIFY-QCLYGKKPFGH-------NQSQATILEENTILKATEV-------------------------------
  ..|||.    |  | ..| |||| ||  .  . ||..|          ||     ...   ..  .                                
RWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

-----QF
     .|
SEIHECF
Kinase tlk.AA Pkinase_Tyr 953-1074 32 2.1e-10 35.83 Pfam 51-176 (270) Show / Hide 
Range on Protein: 953-1074
Range on HMM: 51-176/270
Sequence Identity: 32% (42 aa)

LREYNIHKAL-DHPRVVKLYDVFEIDANS--FCTVLEYCDGHDLDFYLKQH----KTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGN
.|| .| | | .|| .|.|| |   .  .   . |.||. . ||. ||..|    . ..  .  .. .|. ... || ...   || ||   |.|.||.|
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN

VCGEIKITDFGLSKVM-DDENY-NPDHGMDL
|.   ||.||||.. . .|..|    .| .|
VV---KICDFGLARDIYNDDYYYRKRGGGKL
Kinase tlk.AA PLK-Unclassified 1100-1122 56 0.001372 9.69 In-house 186-208 (264) Show / Hide 
Range on Protein: 1100-1122
Range on HMM: 186-208/264
Sequence Identity: 56% (13 aa)

SSKVDVWSVGVIFYQCLYGKKPF
| .||.|| |.| |  | || ||
SYEVDCWSFGCILYTLLIGKPPF
Kinase tlk.AA Pkinase_Tyr 1085-1107 43 2.975122 1.48 Pfam 181-199 (270) Show / Hide 
Range on Protein: 1085-1107
Range on HMM: 181-199/270
Sequence Identity: 43% (10 aa)

LPPECFVVGKNPPKISSKVDVWS
..|||.  ||     ..| ||||
MAPECINYGK----FTTKSDVWS