Gene ver-1 (Nematode worm)
ver-1
Species: Nematode worm
Alias: ver-1/, F40G9.13, ver-1, CE19860, aSWK385, T17A3.1
External Links:
Annotation:
Sequence
Protein domains of ver-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| IG | ver-1.AA | IG | 69-148 | 16 | 1.2e-05 | 26.01 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 69-148 Range on HMM: 1-58/58 Sequence Identity: 16% (14 aa) GKFVELTEGQTLSLQCAYRRGTPKFTYPNFLAERVEQEFSEPLNTDYVRIEDIRESDT---GSFSCNSTENPAQS-DSIHVFVH . |. ||.|..|.| . . | .| .....|. | . | | ..| ..... |. PP-VTVKEGETVTLTC-VS---QIWWY--------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | ver-1.AA | IGc2 | 75-138 | 15 | 0.004063 | 4.79 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 75-138 Range on HMM: 1-56/56 Sequence Identity: 15% (10 aa) TEGQTLSLQCA-YRRGTPKFTYPNFLAERVEQEFSEPLNTDYVRIEDIRESDTGSFSCNSTENPA |||...|.| . .| .. .... . ...|......| | .| . . HEGQSVTLTCPATGNPDPNIHWYK--GQPLP-------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | ver-1.AA | IG | 251-349 | 12 | 0.154778 | 4.3 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 251-349 Range on HMM: 1-58/58 Sequence Identity: 12% (13 aa) DSFPFPHVGYNFSLTCHLVYIEPNGNAPKLGELAFECPQCQSRLDNHLVIEKHHNVGRKRLSSAIHIKNLQLRDA---GKYRCIWKKTGKARQEI--EHS . .| . .||| .. ..| |.|. |. | |.| . . .. . PP-VTVKEGETVTLTC-VS------------QIWWY----------------------------LTI-NVQPEDSQQHGTYYCQAT---HGQYWSIQGTT LHVS |.|. LTVQ |
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| I-set | ver-1.AA | I-set | 317-331 | 53 | 0.482893 | 6.05 | Pfam | 62-76 (92) | Show / Hide |
Range on Protein: 317-331 Range on HMM: 62-76/92 Sequence Identity: 53% (8 aa) IKNLQLRDAGKYRCI |.| | .|.|||.|. ISNVQPDDEGKYTCV |
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| IG | ver-1.AA | IG | 362-458 | 10 | 0.287331 | 1.97 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 362-458 Range on HMM: 1-58/58 Sequence Identity: 10% (11 aa) PSFLKAKAGSGSVKLYAKFAVYPAGNYTVTWRRTYNSIEGPRDEIVEKGLSATFLENSESMEVLDITDLSCNKS---GKYLLSINYQDTSETI--FWEVA |. . .|. ..|.| .. ...|. | | ... . | | | . . . . .. PP-VTVKE-GETVTLTC-VS-------QIWWY-------------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLT VE |. VQ |
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| IG | ver-1.AA | IG | 571-655 | 23 | 2.4e-10 | 41.62 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 571-655 Range on HMM: 1-58/58 Sequence Identity: 23% (21 aa) SNKSAIYEGDTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTEHSQLSFLYIRNATTSAS---GNYTCVLENQASENFS-LSTILKVE . ||.||.||| |. .|.| | | |.. . | |.|.|. . . . .| .| |.|. PP-VTVKEGETVTLTC-VS------QIWWY--------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| IGc2 | ver-1.AA | IGc2 | 577-643 | 28 | 5.8e-05 | 22.46 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 577-643 Range on HMM: 1-56/56 Sequence Identity: 28% (19 aa) YEGDTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTEHSQLSFLYIRNATTSASGNYTCVLENQAS ||..| ||| . .|.|.. . | ..| |.|.| . ||.|||. .| .. HEGQSVTLTCP-ATGNPDPNIHWYK--GQPLP--------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | ver-1.AA | I-set | 596-654 | 22 | 0.276829 | 6.87 | Pfam | 31-92 (92) | Show / Hide |
Range on Protein: 596-654 Range on HMM: 31-92/92 Sequence Identity: 22% (14 aa) SITWVHRNLSILH---STEVTEHS-QLSFLYIRNATTSASGNYTCVLENQASENFSLSTILKV ...| . . . .|. . ..| |.|.. . .| |||| .| . | . . |.| QVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAEC-TAELTV |
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| I-set | ver-1.AA | I-set | 674-732 | 29 | 1.4e-10 | 38.41 | Pfam | 19-92 (92) | Show / Hide |
Range on Protein: 674-732 Range on HMM: 19-92/92 Sequence Identity: 29% (22 aa) KLDCNIDGRPPPEYQWFKDGTPYGT-GRRLKFFEED--------------NSGIYQCLATNRAGSATNSFELKT ...|...| |||. .||||| | . ..| .. ... .|.| | |||..|.|. ..||. RFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | ver-1.AA | IGc2 | 669-722 | 31 | 4e-06 | 27.72 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 669-722 Range on HMM: 1-56/56 Sequence Identity: 31% (18 aa) APTGS-KLDCNIDGRPPPEYQWFKDGTPYGTGRRLKF--FEEDNSGIYQCLATNRAG . .| | | .|.| |. .|.| |.| .. .|.. .... ||.|.|.|.|..| HEGQSVTLTCPATGNPDPNIHWYK-GQPLPWNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | ver-1.AA | IG | 664-733 | 13 | 0.125824 | 5.08 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 664-733
Range on HMM: 1-58/58
Sequence Identity: 13% (11 aa)
KTGFSAPTGSKL--DCNIDGRPPPEYQWFKDGTPYGTGRRLKFFEEDNS-----GIYQCLATNRAGSATN--SFELKTA
.. |. . | . ...|. | . . . |.|.| || .|... ...|.
PP-VTVKEGETVTLTC-VS-----QIWWY-----------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
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| Kinase | ver-1.AA | KIN16 | 803-1072 | 43 | 8.70000000001e-197 | 582.95 | In-house | 1-332 (332) | Show / Hide |
Range on Protein: 803-1072 Range on HMM: 1-332/332 Sequence Identity: 43% (146 aa) LEILEPIGSGHFGVVRRGILKGT----------KTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHPNVLALVGAITKNLRQGE---LYILMEYIDGGN ||..||.|||||||||.|.|. . .. |||||..... | .||.|..|||.|.||.|||||||||||.|||.|||. |.| .||...|. LEFEEPLGSGHFGVVRKGLLHMKNPKNEKEHKNRLEVAVKSPANPHDICQQKMIYDELKVMCAIGKHPNVLALVGAVTKNMRQGGRHMLMIVTEYVECGD LRDFLQQRRNVFIDELHD----------------------NFDENIPLIRPD-FNSLSTTDLVGIAHQIANGMEWLGNVPC-VHGNLCCRKVLISKTKTI ||.||.|.||.|...... ||.||..|...| |.||.|.||. .|.|||||||||..||| ||..|.||.|.|...|.| LRKFLRQHRNNFQNHQVCWDNERQSGYNINNKERKHYVFKNFCENEQLVIKDIFDSLCTSDLLSFAYQIANGMEWLAHVPCCVHRDLACRNVFIKRNKII RITDYGVGDRQRKSS------------SMRWMAPEAIEH-----QMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTEN--------ILKHIKNGSRNLQP ||.|.|......... .|||||||..|. ..|..||||||.|.||||||.||.||||.| ..| .......| |. || RIADFGLARWHENKDYYRMKSSMDTPLPMRWMAPECFEEEQERKMKFTEKSDVWSYGVCLYEIFSLGETPYPNCPNNNCRDDYFQYVMEYLRKGNRLPQP EYCPSALYDLMQLCWRAPPQDRPKFSLCSELI |.|.. .||.|..||...|..||.|| | |.. EHCHPEIYDFMKMCWNFDPEKRPTFSECVEFF |
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| Kinase | ver-1.AA | Pkinase_Tyr | 803-1072 | 33 | 2.3e-98 | 333.73 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 803-1072 Range on HMM: 1-270/270 Sequence Identity: 33% (97 aa) LEILEPIGSGHFGVVRRGILK----GTKTVVAVKSS--SYRSS-IGFQKVIVEELKLMSAIPKHPNVLALVGAIT-KNLRQGELYILMEYIDGGNLRDFL ..... .|.|.||.|..|..| .||. ||||. .. .. ... .|.|.|. ...|||.. |.|..| . . ..|| ||| .|.|.|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL QQRRNVFIDELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVGDRQ-------RKSS----SMR ...| .| ..|.. ||.....|||.|||.| . .|.| |..| .|........|.| | ||.. . RKHR-------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK WMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTP-YPTCVTENILKHI-KNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELI |||||.| . |..||||||||....||||.|..| || . | ....| ..| | .||.|| .||||..||.. |.||| || . | . WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | ver-1.AA | TK | 803-1072 | 20 | 1.9e-94 | 317.05 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 803-1072
Range on HMM: 1-486/486
Sequence Identity: 20% (99 aa)
LEILEPIGSGHFG---VVRRGILKG---------------------------TKTVVAVKSSSYRSSIGFQKV--------------IVEELKLMSA-IP
..... .|.|.|| .|..|...| |.. |... . .| .. .||.|.|.. .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
KHPNVLALVGAITKN---------LRQGELYILMEYIDGGN----LRDFLQQRRNVFID---------------------------ELHDNFDENIP---
.|||.. |.|..|.. . |. ..|.||| ..|. |||.|...|. |.. ....| .. ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD
----LIRPDFNSLSTTDLVG-------------------IAHQIANGMEWLGNVPC------VHGNLCCRKVLISKTKT-----------IRITDYGVGD
||......|.|.||. ...|||.|||.| .| ||..|..| .|... .. ..|.|.| .
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----RQRKSSS-------------------------------------MRWMAPEAIEHQM---------FSSKSDVWSFGICLYEIFTLGGTPYPTCV
. |. | ||||||..... |..||||||||....||||.| .||. .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
T----------ENILKHIKNG--------------SRNLQPEYCP--------------SALYDLMQLCWRAPPQDRPKFSLCSELI
. . .......| | ||..|| ..||||| ||.. |.||| || . | .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | ver-1.AA | TyrKc | 803-1072 | 30 | 1.5e-90 | 308.05 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 803-1072
Range on HMM: 1-280/280
Sequence Identity: 30% (93 aa)
LEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAI-PKHPNVLALVGAITKNLRQ----GELYILMEYIDGGNLRDFLQQR
.. .. .|.|.||.|..|..| . ||||. . .. . .|...|. . ..|||...|.|..|. |. . |.|.||| ..|.|.|.|. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH
RNVFIDELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYG----VGDR-------QRKS-----SS
|. |.. ||. ...|||.||| | .|.| | .| .|... .|..|.| | ..| . .. ..
RPK----------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGG
M-----RWMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPT-----CVTENILKHIKNGSRNLQPEY--------CPSALYDLMQLCWRAPPQDRP
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KTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP
KFSLCSELI
|| . |..
TFSEIHECF
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| Kinase | ver-1.AA | TK-Unique | 803-1072 | 32 | 2.6e-81 | 276.46 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 803-1072 Range on HMM: 1-294/294 Sequence Identity: 32% (98 aa) LEILEPIGSGHFGVVRRGILKGTK------TVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGGNLRDFLQQ ||... ||.| || | || ..|.. ..|||| ... .. |...|.....|||.. ..|. ||. . .|.|||. .|||...|.. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQHYLRT RRNV--------FIDELHDNFDENIPLIRPDFNS---LSTTDLVGIAHQIANGMEWLGN--VPCVHGNLCCRKVLISKTKTIRITDYGVGD--------- .| . .. ... .||... .| ||. .| |||.||| | .||..|| | ||.. |.. |.|.| . CRPAMRQHQTYGNLK--------FDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS --RQRKSSSMRWMAPEAIE--HQMF-SSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRNLQPEYC-PSALYDLMQLCWRAPPQDRPKFSLC .... . ||||||.. |.|. ..||||||||. ..||||||..||| ..|...|..|.| .|||.| . ..| ||. ||. |..|| |. . MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQI SELI . KHRL |
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| Kinase | ver-1.AA | UTK | 803-1071 | 27 | 3.8e-63 | 214.87 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 803-1071
Range on HMM: 1-296/296
Sequence Identity: 27% (86 aa)
LEILEPIGSGHFGVVRRGILK-----GTKTVVAVKSSSYRSSIGFQK----VIVEELK---LMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGGNL
.......|.|.||.|... .. ... .|||| . ... ... . || . .|.. ||||| ||| |. .. ..|..|| .|.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQ---EEPWMIVTEYMENGDL
RDFLQ-QRRNVFIDELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKT-------KTIRITDYG-------VGD-
|..|. .|.... .. .|. ..... | .||.||. | . .||..|..| .|. . ...| |.| |..
RSYLRRHRPTPP----------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTF
--------------RQRKSSSMRWMAPEAIEHQ-MFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNG--SRNLQPEYCPSALYDLMQLCWRA
..... .|||||||. |. |..||||||||. ..||.| | .||| ...... . || | .|. || ..|.||. ||..
HFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHY
PPQDRPKFS-LCSEL
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DPQERPDFEDLVQQM
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| Kinase | ver-1.AA | KIN6 | 877-1072 | 32 | 5.9e-52 | 169.89 | In-house | 92-305 (305) | Show / Hide |
Range on Protein: 877-1072 Range on HMM: 92-305/305 Sequence Identity: 32% (71 aa) ELYILMEYIDGGNLRDFLQQRRNVFI--DELHDNFDENIPLIRPDFNS---LSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTK---TIRIT ..... || . ..| .|..|. . |.| |. |. . . .. ||. .| ||..||| | . |.| | | ||. . | | KPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINYH--CPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKIS DYGVGD------RQRKSSSMR-----WMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCV-TENILKHIKNGSRNLQPEYCPSALYDLMQLCWR | | | .| . | |||||...| || ||||||||. ..|.|.||. |||. .. .. |.. | | ..|..|| || ||.|| DFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQ APPQDRPKFSLCSELI . | ||| |. . .. EKPDDRPEFNEMRMQF |
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| Kinase | ver-1.AA | TKL | 809-1072 | 20 | 5e-45 | 155.91 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 809-1072 Range on HMM: 1-364/364 Sequence Identity: 20% (82 aa) IGSGHFGVVRRGILKGTK--------TVVAVKSSSYRSSIG--------------------------FQKVIVEELKLMSAIPKHPNVLALVG-AITKNL ||||.||.| .|...|. ..|||| . ... |.. ..||...|| . .|||.. ..| .. . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRL-RHPNIVQFMGYCCCPPC R---------QGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGN--------VPCVHGNLCCRK . .|.|.| |||..||.|...|. .. .|..|| ||..| . | .| .| . GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKN VLISKTKT--------------IRITDYG-------------------------VGDRQRKSS--SMRWMAPEAIEHQ----------------MFSSKS .|. . | . |.|.| ... .. . . ||||||... | .| |. ILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKC DVWSFGICLYEIFT--LGGTPY--PTCVT--------ENILKHIKNGSRNLQP------------EYCPSALYDLMQLCWRAPPQDRPKFSLCSELI ||.||||.|.||.| . || . . . | . . ...| | . | ..|| . .||| || . |..|| |. . . . DVYSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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| Kinase | ver-1.AA | Src | 982-1071 | 44 | 8.6e-37 | 122.49 | In-house | 164-255 (255) | Show / Hide |
Range on Protein: 982-1071 Range on HMM: 164-255/255 Sequence Identity: 44% (41 aa) MRWMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRNLQPEYCPSALYD-LMQLCWRAPPQDRPKF-SLCSEL ..|.||||| .. |. ||||||||| |.||.| | .||| . |.....| | .|. || ||. .|. ||.. |..|| | |.. | IKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | ver-1.AA | FGFR | 984-1072 | 41 | 5.5e-35 | 116.66 | In-house | 204-293 (293) | Show / Hide |
Range on Protein: 984-1072 Range on HMM: 204-293/293 Sequence Identity: 41% (37 aa) WMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCV-TENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELI |||||| ... ..|||||.|. | ||.|.||.|||. | . | | | | |. |.. .| .| ||.. |..|| | | . WMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL |
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| Kinase | ver-1.AA | VEGFR | 982-1075 | 43 | 2.7e-33 | 116.92 | In-house | 241-332 (332) | Show / Hide |
Range on Protein: 982-1075 Range on HMM: 241-332/332 Sequence Identity: 43% (41 aa) MRWMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCV-TENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELIEKQ ..|||||.| ....|||||.|. | |||.||| |||. . | . .|.| | |.||. ..|. |. ||. | || | ||| |. IKWMAPESIFDKVYTTYSDVWSYGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHF---SELVEHL |
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| Kinase | ver-1.AA | Csk | 921-1072 | 33 | 1.1e-31 | 105.38 | In-house | 92-251 (251) | Show / Hide |
Range on Protein: 921-1072 Range on HMM: 92-251/251 Sequence Identity: 33% (54 aa) NSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVGDRQRKSSS--------MRWMAPEAIEHQMFSSKSDVWSFGICLYEIF . ... .| | ...||. | || | | .|.| . |.| .. . | |||| | ||.||||||||| | ||. HVITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIY TLGGTPYPTCVTENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELI | ||| . . ||. | | || || . | .|. || . |..|| | | SFGRVPYPRIPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL |
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| Kinase | ver-1.AA | S_TKc | 803-1076 | 22 | 5.1e-28 | 100.33 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 803-1076 Range on HMM: 1-231/231 Sequence Identity: 22% (63 aa) LEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDG--GNLRDFLQQRRNV |||..||.| ||.|.... |.|. .||.| . . | |..... .|||. | ... ..||. |||.|| |.|.|....|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRH FIDELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVGDRQRKSS--SMRWMAPEAIEHQMFSS- . .. . ...||....| . . .| | .|... .| |.| |. . .. . .|||| . .. GLR-----------------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVL---GYGKC KSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSE-----LIEKQL |.|.||.|..||| .. | .|.| . ..|.|. .. . |... |.. |..|| . . . . KCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | ver-1.AA | FGFR | 847-971 | 35 | 1.1e-20 | 67.23 | In-house | 52-181 (293) | Show / Hide |
Range on Protein: 847-971 Range on HMM: 52-181/293 Sequence Identity: 35% (48 aa) VEELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNF---DENIPLIRPDF------NSLSTTDLVGIAHQIAN | |. | | ||.|.. | |. | . | ||.. || |||||||..|| | | |. |.. . |. ||| .|.|.| VSEMEMMKMIGKHKNIINLLGCCTQE---GPLYVIVEYCHHGNLRDFLRARRPPGMDYKKDSQEYTDYK-PRKPEQQDDIELIPNLTQKDLVSCAYQVAR GMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYG |||.| |.| | | ||.. . | |.| GMEYLASRKCIHRDLAARNVLVTDDYVMKICDFG |
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| Kinase | ver-1.AA | Pkinase | 803-901 | 29 | 2.5e-19 | 69.43 | Pfam | 1-103 (293) | Show / Hide |
Range on Protein: 803-901 Range on HMM: 1-103/293 Sequence Identity: 29% (32 aa) LEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVE---ELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGG----NLRDFLQ ..|...|||| ||.|.... ||| .|||| ..|. .... |...| . .|||.. | .. . ...|. ||| .|| | |... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIS -QRRNVF .|...| TWRHGCF |
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| Kinase | ver-1.AA | Csk | 803-897 | 38 | 6.2e-16 | 50.89 | In-house | 1-89 (251) | Show / Hide |
Range on Protein: 803-897 Range on HMM: 1-89/251 Sequence Identity: 38% (37 aa) LEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHPNVLALVGAITKNLRQG-ELYILMEYIDGGNLRDFLQQR |...| || | || |. |.... | |||| .. . |. .. | . | . .||| .|.| | | |. .||| |||. ||| |.| | LHLGECIGHGEFGDVMQGEYQNRK--VAVKCIKCDGNGMAQA-FLAEASVMTQL-RHPNLVQLIGVI---LHQKNHLYIVMEYMSKGNLVDYLRSR |
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| Kinase | ver-1.AA | Src | 803-971 | 23 | 1.4e-13 | 42.41 | In-house | 1-142 (255) | Show / Hide |
Range on Protein: 803-971
Range on HMM: 1-142/255
Sequence Identity: 23% (39 aa)
LEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGGNLRDFLQQRRNVFI
. .. .|.|.|| | |. .|. | ||||. . . .. .| ..| .|.....| .. || || |.| |.|..
IKLCRKLGQGQFGEVWMGYWNGN-TKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEE---PIYIVTEYMSHGSLLDYLKK------
DELHDNFDENIPLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYG
... .|. ..|. .| |.|.||. |. .| | | ||.... . | |
--------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFG
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| Kinase | ver-1.AA | VEGFR | 849-904 | 37 | 1.4e-10 | 36.32 | In-house | 52-107 (332) | Show / Hide |
Range on Protein: 849-904 Range on HMM: 52-107/332 Sequence Identity: 37% (21 aa) ELKLMSAIPKHPNVLALVGAITKNLRQGELYILMEYIDGGNLRDFLQQRRNVFIDE |||.. | .| || . |. |||. .|.| . .|| ||| ..| |. | . ELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRMYFVPY |
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| Kinase | ver-1.AA | Pkinase | 983-1063 | 22 | 2.4e-10 | 37.68 | Pfam | 176-282 (293) | Show / Hide |
Range on Protein: 983-1063 Range on HMM: 176-282/293 Sequence Identity: 22% (24 aa) RWMAPEAIE-HQMFSSKSDVWSFGICLYEIFTLGGTPYPTC----VTENILKHIKNGSRNLQPEYCP-----------------------SALYDLMQLC ..|||| | .|. ..|.|.||.|. ||| .. | .|.| . . .. |.. . .. .| ... |.. | WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC WRAPPQDRP .. |..|| LCKDPKKRP |
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| Kinase | ver-1.AA | VEGFR | 923-971 | 34 | 1e-06 | 21.46 | In-house | 170-218 (332) | Show / Hide |
Range on Protein: 923-971 Range on HMM: 170-218/332 Sequence Identity: 34% (17 aa) LSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYG | . ||. . |.|.||| | |.|. | | .|.. ... | | | LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFG |
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| Kinase | ver-1.AA | APH | 805-907 | 15 | 0.000833 | 13.86 | Pfam | 1-105 (248) | Show / Hide |
Range on Protein: 805-907 Range on HMM: 1-105/248 Sequence Identity: 15% (17 aa) ILEPIGSGHFG-VVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKH-P--NVLALVGAITKNLRQGELYILMEYIDGGNLRD---FLQQR ..||..| . ...|. .... |. . ... . . .|.... .. .| . | .... | . .| .. |||...| |.. .. WWRPISGGWSNRTYYRTTDDRPRYVLRRYPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLMEWLPGEDLWRWHALHCAQ RNVFIDELHD | ....|.. RPALLEALAR |
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