Gene kin-3 (Nematode worm)

kin-3

Species: Nematode worm
Alias: KC2A_CAEEL, kin-3, CE17321, aSWK212, B0205.7
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
kin-3.AA Protein None 360 None Fasta, JSON
kin-3.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of kin-3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase kin-3.AA CK2 38-323 76 9.20000000001e-235 709.51 In-house 1-288 (288) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-288/288
Sequence Identity: 76% (220 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKV--VVKILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYY
|...||.|||||||||||......||.  |.|||||||||||||||||||||.||.|||.|.|.||||.|..|||.||.||| ||.||||||.|||||||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

LYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGH
..|||||||.|||.|||||||||||.|||.|||.||||||||||||||.|||||||||||.||||||||||.|||||||||||||.|||||.||||||||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYF
|||||||.|.|||||..||.|...|.|.|||.|.||...|..|.||||||.||.||..|||.|||||.|||||.||.||.|||.|.||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase kin-3.AA CMGC 38-323 20 1.4e-99 327.93 In-house 1-513 (513) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-513/513
Sequence Identity: 20% (103 aa)

YQLVRKLGRGKYSEVFEGFK--------------MSTDEKVVVKILKPVKKKKIK---------------REIKILENLR----------------GGTN
|. ..|.|.| |..|....               . |.|.| .|..| .. ...                ||||||..|.                   |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IITLLDVVKDPISRTP---------------ALIFEHVNNSDFKQLYQ-----------TLSDYD------------IRYYL------YELLKALD--FC
|..|.|..... |...                |.||.. .. .. ...            ||.              |.|..      | .|..|.  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSQG--IMHRDVKPHNVMIDAEKRE-------------------LRLIDWGLAEFYHPRQD----------------------YNVRVASRYFKGPELLV
||..  |.||| || |..|. ...                    |...|.||| .|||..|                      |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DYQCYD---------YSLDMWSLGCMLASM-------IFRKEPFFHGHDN-----------YDQLVRIAKVLG------------------TDELYEYIA
 .. |.         .. ||||.||..| |       |||..|.|.||..           .||| .| ||||                  ..| ...| 
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

RYHIDLDPR----------FNDI----------LGRHSRKRWERFIHAENQ------------------------------HLVTPEALDFLDKLLRYDH
 .. ...|           ...           .... .| |....   .                               .. .|.|.|.|.|.|.||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

AERLTAQEAMGHEYF
..|.||..|. |.||
DKRITAEQALQHPYF
Kinase kin-3.AA Pkinase 38-323 25 6e-86 296.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-293/293
Sequence Identity: 25% (81 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKR-------EIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNS----DFK-----
|...||.|.| ...|... . .| ..|.|||.| ...|. |.       ||.|. .| .  ||..|.|.. |  .. . ...|....     | .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

QLYQTL--SDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKREL----RLIDWGLAEF--YHPRQDYNVRVASRYFKGPELLVDYQCYDYSLD
. . ..  |. ... |.|..|..|..|||.||.|||.|| |..|| .. ..    ...|.|||..  | . . ..... ....  ||.. ..| |... |
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWSLGCMLASMIFRKEPFFHG---HDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAE
|||.||.|. |.... || .    .. .||...|....|..  ...   . | ... |..   .        | | .. |....|..||....|..| ..
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKK

RLTAQEAMGHEYF
|.||.... |..|
RPTAEQILQHPWF
Kinase kin-3.AA S_TKc 38-323 25 1.2e-72 248.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-231/231
Sequence Identity: 25% (77 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNN--SDFKQLYQT---------
|...||.|.| ...|. . . .|...| .||.|    ..|.|||.||..  .  ||..|.||  |       ...|....   | ... .          
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCYDY-SLDMWSLGCMLASMI
..  ..|.|.|....||..|||.||.|||.|| |...|    .. ..| ||| ..      .  . ....  ||.|     |.. . |.||.||.|. |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMG------
 .. ||        |. .. |..|                                           .|||.||..|.|..| ..|.|| ||.       
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HEYF
 |..|
CHPWF
Kinase kin-3.AA CAMK 43-231 18 5.1e-46 145.85 In-house 1-334 (425) Show / Hide 
Range on Protein: 43-231
Range on HMM: 1-334/425
Sequence Identity: 18% (61 aa)

KLGRGKYSEVFEGFKMSTD------------EKVVVKILK-------------------------------PVKKKKIKREIKILENLRG------GTNI
.|||| ...|....  .|             .|| .||..                               |...|...|||.|. .|.|        ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLLDVVKDP----------ISRT--------PALIF---EHVNNS----D-FKQLYQT-----------------LSDYDIRYYLYELLKALDFCHSQG
| |..|  ||            ..          ...   |.. .     | |  . .                  ..  . |.|   .. |...|||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPHNVMIDAEK----------------RELRLIDWGLAEFYHP------------------------RQDYNVRVASRYFKG-PELLVD-----
|.||| || |...|  .                  . .||.|.| .. |                         | .. .. . ..   ||.|       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------YQCYDYSLDMWSLGCMLASMIFRKEPF
         . |... ||||.|..|  |   . ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase kin-3.AA CDK 38-250 28 5.9e-45 141.68 In-house 1-243 (284) Show / Hide 
Range on Protein: 38-250
Range on HMM: 1-243/284
Sequence Identity: 28% (71 aa)

YQLVRKLGRGKYSEVFEGFKMSTD-----EKVVVKILK-PV-----KKKKIK----REIKILENLRGGTNIITLLDVVKDPIS---------RTPALIFE
|. . |.|.| | .|. .  . |.     . |  | ..        .|  .     |||..| .|    ||..|.||. .  .         ..  ..||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

HVNNSDFKQLYQTLSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKR----ELRLIDWGLAEFYH-------PRQDYNVRVASRYFKGPELL
..   | |..        |. |.. ||..|..|||..||||| || | .|.         | . | |||  ..       |.. |  .|  .    ||||
YMDH-DLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELL

VDYQCYD--YSLDMWSLGCMLASMIF--RKEPFFHGHDNYDQLVRIAKVLGT
   ..|.   . ||||.|| .| |.    ..|.|.|    ||| .| ...||
LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT
Kinase kin-3.AA Ciliate-E2 38-323 15 1.4e-41 140.45 In-house 1-365 (365) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-365/365
Sequence Identity: 15% (66 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEK-----------------------VVVKILKPVKKKKIKREIKILENLRGGT----------------NIITLLD
| ...|.|.| .. |... . .....                       . .||.|. ... ||.||.|.  ..                   ||| . .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

VVKDPISRTPALIFEHVNNSDFKQLYQ--------------TLSDYDIRYYLYELLK---------------ALDFCHSQG-IMHRDVKPHNVMIDAEKR
. ..    .  |..| ..  | ... .               .... |.|. ...|.               || ..||.. |.||| || |...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

ELRLIDWGLAEFYHPRQD--------------------------------YNVRVASRYFKGPELLV--DYQC------YDYSLDMWSLGCMLASMIFRK
 . .||.||. .|.. ..                                .|  . . ... || |   .|.       |||. |.||||..|  |.| |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

EPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHL--------------------------VTPEALDFLDK
 ||                                                       ....                           ...|. |.. |
PPF------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK

----LLRYDHAERLT-AQEAMGHEYF
    .| .|  .|.| ..... |..|
FGKRMLQKDPEKRITGWEQILNHPWF
Kinase kin-3.AA ERK7 38-323 27 2.7e-36 121.41 In-house 1-292 (292) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-292/292
Sequence Identity: 27% (82 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKIL-----KPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQ---TLSD
|.. ..||.| |  |   .   | . | .|        ..   .  ||| .| ....  ||| |..|..    |   |.||.  ..|     .    | |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFM-ETDLHAVIRKGNILKD

YDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVR-------VASRYFKGPELLVDYQCYDYSLDMWSLGCMLA
   .| .| ||.|. . ||  ..|||.|| |...|.| . ... | |||     ...|.         || | .  || |.  . |    ||||.|| |.
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECM-VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

SMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEY
 |.  | | | |    .|. .| ....    .| |.    ..     . .... ||  . ..         ..|.| | .|| .   .||||..|. | |
EMLRGK-PMFPGTSTMNQIEKILETIPKPT-QEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ-----CCDDAIDLLKRLLVFNPKKRLTAEQALQHPY

F
 
V
Kinase kin-3.AA Ciliate-E2-Unclassified 38-323 17 1.5e-35 120.78 In-house 1-352 (352) Show / Hide 
Range on Protein: 38-323
Range on HMM: 1-352/352
Sequence Identity: 17% (66 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKK---------IKREIKILENLR------------------GGTNIITLLDVVKDPISRTPAL
| .....|.| ...|..  . ..... . |..| ....|         |..|.|...|.                      .|. .... .|    .. .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ--NIYI

IFEHVNNSDFKQLYQT--------------------LSDYDIR-----YYLYELLKALDFCHSQG-IMHRDVKPHNVMIDAEKR--ELRLIDWGLAEFYH
. | ... | .|  .                     .... ..     .|....|..|...|... | ||| || |...| ...  ....||.|.. .| 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------PRQDYNVRVASRYFK----GPELLVDYQCYD----YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIA
                ..| .. .. . ...     ||.| . | ||    |. |.||||. |  |.| . ||.   .. .| . .... . .       
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL-QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N-N-------

RYHIDLDPRFNDILGRHSRKRWERFIHAENQ-----------HLVTPEALDFLD----KLLRYDHAERLTAQEAMGHEYF
         .        ||  .. |.. |.           . . ||| ||.     |.| ..  .|.|..... | .|
---------A-------YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase kin-3.AA CDC2 38-250 31 4e-35 105.02 In-house 1-227 (301) Show / Hide 
Range on Protein: 38-250
Range on HMM: 1-227/301
Sequence Identity: 31% (73 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIK--------REIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQ----
|| ..|.| | | .|. .  | |.. |..|  . ..             ||| .| .|.   ||..| ||..    .   ..|| . . | |..      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

---TLSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLA-EFYHPRQDYN--VRVASRYFKGPELLVDYQCYDYSLDMWSLGC
    ..   .. |.| .|....|||...||||| || |  ||.. . ... | |||  |  |   |     |  .    ||.|   . |. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MLASM-IF-RKEPFFHGHDNYDQLVRIAKVLGT
 .| | .   |.|.|||    ||| .| ..|||
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGT
Kinase kin-3.AA CDK5 38-250 34 1.5e-33 102.99 In-house 1-218 (287) Show / Hide 
Range on Protein: 38-250
Range on HMM: 1-218/287
Sequence Identity: 34% (76 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKK-----KKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFK----QLYQTLS
|. . |.| | |  |. .    | | |  |  .             ||| .|  |.   ||. | ||.     .   |.||.. . | |    ..   ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIH--SEKKLTLVFEFCDQ-DLKKYMDSCNGEMD

DYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAE-FYHPRQDYNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFR
   |....| ||| | |||.. ..||| || | .|   . ||.| | |||  |  | . |   |    .  |  |   . |  | |||| || .| |.  
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLI-NKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

KEPFFHGHDNYDQLVRIAKVLGT
  | | | |  ||| || |..||
GRPLFPGNDVEDQLKRIFKIMGT
Kinase kin-3.AA RCK 38-250 28 1.2e-32 100.68 In-house 1-232 (298) Show / Hide 
Range on Protein: 38-250
Range on HMM: 1-232/298
Sequence Identity: 28% (68 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIK-----REIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQT------
||....||.| |..|... .  | |.|  | .|  | ....     |||| |  |    ||| |..|..|  ... ...||.. . .  |....      
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDM-NLYQMMKDFKERRK

-LSDYD--IRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAE--------KRELRLIDWGLA-EFYHPRQ---DYNVRVASRYFKGPELLVDYQCYDYS
 |.     |. ..| .|..|...|..|..|||.|| | |.  .           . ..| ||. |..  ..   ||   | .|.   ||.|   . |.. 
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRS-KPPYTDY---VSTRWYRAPECLLRCTYYNSP

LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT
.|.|..||  .  .  . | | | .  ||.  | ||.||
MDIWAVGCIMY-ELYMLRPLFPGSSEIDQIFKICKVMGT
Kinase kin-3.AA CDK 298-323 46 2.5e-11 32.32 In-house 259-284 (284) Show / Hide 
Range on Protein: 298-323
Range on HMM: 259-284/284
Sequence Identity: 46% (12 aa)

DFLDKLLRYDHAERLTAQEAMGHEYF
|.|.|.| || . |..|..|. |.||
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase kin-3.AA CDC2 288-323 44 5.2e-11 29.54 In-house 266-301 (301) Show / Hide 
Range on Protein: 288-323
Range on HMM: 266-301/301
Sequence Identity: 44% (16 aa)

NQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYF
||  ..||..| |...|.|| . |..|.||. | ||
NQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase kin-3.AA CDK5 297-323 37 3.2e-10 28.01 In-house 261-287 (287) Show / Hide 
Range on Protein: 297-323
Range on HMM: 261-287/287
Sequence Identity: 37% (10 aa)

LDFLDKLLRYDHAERLTAQEAMGHEYF
.|.| |.|... ..|..|..|. | ||
MDLLQKMLQCNPNQRISAKAALHHPYF
Kinase kin-3.AA TyrKc 38-280 17 3.2e-09 -73.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-280
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKREIKILENL-RGGTNIITLLDVVKDP-----ISRTPALIFEHVNNSDFKQLYQTLSD--
 .| .|||.| . ||..|      ..| || ||. ... . ||..|. .|     ||. |. |. ..      .  . ...|.. . | |.  .   .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

--YDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPR-------QDYNVRV--ASR-----YFKGPELLVDYQCYDYSLD
   |  .. .   .  .. ||... |||    |.......   .  | ||. . .         . | ..    ..         || . .| ..    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWSLGCML---ASMIFRKEPF-----FHGHDNYDQLVRI----AKVL--------GTDELYEYIARYHIDLD----PRFNDILGRHSRKRW
 || | ..    .      |          . . .. .                  .||.|. | .   . |    |.|..|     ....
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-----HECF
Kinase kin-3.AA CAMK 292-323 28 8.1e-09 23.79 In-house 394-425 (425) Show / Hide 
Range on Protein: 292-323
Range on HMM: 394-425/425
Sequence Identity: 28% (9 aa)

VTPEALDFLDKLLRYDHAERLTAQEAMGHEYF
|..|. |.. |.|..|  .|.|..... |. .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase kin-3.AA RCK 293-323 35 3.2e-08 21.9 In-house 268-298 (298) Show / Hide 
Range on Protein: 293-323
Range on HMM: 268-298/298
Sequence Identity: 35% (11 aa)

TPEALDFLDKLLRYDHAERLTAQEAMGHEYF
...... . |.|..|  .| |||.|  | ||
SQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase kin-3.AA APH 138-186 28 1.8e-05 19.51 Pfam 162-210 (248) Show / Hide 
Range on Protein: 138-186
Range on HMM: 162-210/248
Sequence Identity: 28% (15 aa)

ELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELR---LIDWGLAEFYHPRQD
.|.....     ...|.|..|.|||.|   .. |   .|||. | . .| .|
WLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDPHYD
Kinase kin-3.AA Pkinase_Tyr 38-88 29 0.000287 15.08 Pfam 1-62 (270) Show / Hide 
Range on Protein: 38-88
Range on HMM: 1-62/270
Sequence Identity: 29% (18 aa)

YQLVRKLGRGKYSEVFEGFKM----STDEKVVVKILKP---VK---KKKIKREIKILENL-R
 .. .|||.| . ||..|       .|. .| ||.||.    .   ...  ||.||. .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH