DCLK3

Species: Mouse
Alias: DCAMKL3, DCLK3
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: CAMK
Family: DCAMKL

Sequence

Name Sequence Type Origin Length Description Download
DCLK3.AA Protein None 619 None Fasta, JSON
DCLK3.NA RNA None 3498 None Fasta, JSON
DCLK3.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of DCLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DCLK3.AA DCAMKL 343-600 61 1.2e-212 668.66 In-house 1-279 (279) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-279/279
Sequence Identity: 61% (172 aa)

YDIGGVIGDGNFATVKECRHRETK-QAYAMKM-----------------IDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGG
|.|| .|||||||.|.|||||||. ..||||.                 |||...||||...|.|. |.|...||.|..|.|...||...||.|||||||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

DLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVR---PIFTVCGTPTYVAPEILSEKGYGLEV
||||||.||.||.|..||.|.|.|||||...|..||||||.|||||||...||....|||.|||||..|..   |..||||||||||||||.|.|||..|
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
|.||||||||||||||||||||..||.|||..|. |.|||..||||||||.||||....|.|||.|||||||..||||.
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase DCLK3.AA CAMK1 343-600 47 2.6e-155 454.97 In-house 1-276 (276) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-276/276
Sequence Identity: 47% (131 aa)

YDIGGVIGDGNFATVKECRHRET---KQAYAMKMID-KSQLKGKE----DIVDSEILIIQS---LSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIV
| .| .|| | |..|..| |.||   ...||.|.|| |...|.|.    . .. || | ..   ..||||.|..|.||.. ..||.||.|.||.||| ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

ENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLK--LADFGLAKYVV-R--PIFTVCGTPTYVAPEILSE---KGYGLEVDM
|. .. | .|.  .  ...|. .||.|.||||| ||||||   ... |. .|  .|||||.|..       .|.|||| |||||.|     |.|. ..||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSK-IKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDA-AKDLVRNLLEVDPKKRYTAEQVLQHPWI
| .|||.||||||.||| . |. ..|||  |  ...|| ||.||||||  |||.....||||||||||.||.|.||||
WSIGVITYILLCGYPPFYD-ENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase DCLK3.AA CAMK 348-600 29 4.4e-137 444.59 In-house 1-425 (425) Show / Hide
Range on Protein: 348-600
Range on HMM: 1-425/425
Sequence Identity: 29% (127 aa)

VIGDGNFATVKECRHRETK------------QAYAMKMIDKSQLKG---------------------------KEDIVDSEILIIQSLS-------HPNI
..| |.|..||.|.|..|.            | .|.|.|||..||.                           ... | .|| | ..|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLHEVYET-------------------EAEIYLIM---EYVQGG----DLFDAIVEN---------------VKFPEPEAAVMITDLCKALVHMHDKNI
.||.||||.                   . ..|..|   ||..||    |||| |||.                .|.| ||. ..  .| |. ..|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDVKPENLLVQRNEDKSI-------------TLKLADFGLAKYVVR--------------------------PIFTVCGTPTYVA-PEILS-------
|||| ||||.|.. |.| |              ..|..|||.|... .                          .  |.|||| |.| ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EKGYGLEVDMWAAGVILYILLCGFPPFRSPER-----------DQDELFNIIQVGQFEFLSPY------------WDNISDA--------AKD
       ...|| ..|||..||||||.|||.|||... .           .. |||  |. |...| .||            ||.|||         .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVRNLLEVDPKKRYTAEQVLQHPWI
|.|..|.|||.||.|.||.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase DCLK3.AA RAD53 343-600 36 3.4e-121 362.89 In-house 1-305 (305) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-305/305
Sequence Identity: 36% (113 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDK-------SQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYET-EAEIYLIMEYVQGGDLFDAIV-EN
|......| |||.|||..  ..| | .|.| |||       .   .|.| | .|. | . |.||.|........| .   |...|.. ||.||. ||  .
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

VK---FPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQ-RNEDK-------------SITLKLADFGLAKYVVRP--IFTVCGTPTYVAPEILSE
 .   | |...      .| |.   ||..|.||| |||| |    .|..             |. .|..||||.| |.      | ||||.|||||..  
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K---------------GYGLEVDMWAAGVILYILLCGFPPFRSPERDQ----DELFNIIQV-GQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQV
|               ||. .||.| .|.||||.|||.||| | ...|    . ||  |   | ..| .|||| ||. ||||....| |||.||||....
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF-SDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LQHPWI
|.|||.
LNHPWM

Kinase DCLK3.AA CDPK 343-600 43 1.5e-116 358.93 In-house 1-271 (271) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-271/271
Sequence Identity: 43% (119 aa)

YDIGGVIGDGNFATVKECRHR-ETKQAY-AMKMIDKSQLKGKE--DIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIME--YVQGGDLFDAIVENVKF
|.|..|.| |.| .|. . |.  |.|   |||.| ||..| ||  ...  || |  .| ||||.|. |.|. |  .|..||  |. ||.||| |.|. .|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

PEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSI---TLKLADFGLAKYVV-------RPIFTVCGTPTYVAPEILSEKGYGLEVDMWAA
.| |||  .. .  |....|..||||||.||||.| . ..| |    ..|. |.|..|.           . . ||||.|.|||.|  | |  ..| | .
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
|||||||||| |||    . . | .. .. |...|  | ||.||| ||||.|..|..|||||..|.|.|||||.
GVILYILLCGYPPFYG--KNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase DCLK3.AA S_TKc 343-600 37 1e-112 381.71 SMART 1-231 (231) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-231/231
Sequence Identity: 37% (103 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQG--GDLFDAIVENVK-----
|.|. .|| | |..|. |||..|.. .|.|.|.        . . .|| | ..  |||||||..|...  ..|..|||. |  ||||| |... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRPIFTVCGTPTYVAPEILSEKGYGL-EVDMWAAGVILYIL
 ||| .|. ..  .|.|| ..|...|.|||.||||.|. .      ..|..|||||. .     |.|||| |.|||.|   |||  ..|.|. |.|||..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQ-------HPWI
||| |||.    .....|..|               |. |||..|..|..||.||.|| ..||       |||.
LCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DCLK3.AA Ciliate-E2a 343-600 41 3.4e-109 322.55 In-house 1-275 (275) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-275/275
Sequence Identity: 41% (116 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDK---SQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEP
|..  .|| |||. |.  .|..|.. .||| ..|    | |||| . . || |...|.|||| ||.||||.|  .||.|||..||.|.| |... .| | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMN-EINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EAAVMITDLC-KALVHMHDKNIVHRDVKPENLLVQ-RNEDKS--ITLKLADFGLAKYV--VRP--IFTVCGTPTYVAPEILSEKG------YGLEVDM
  |.. ..  |  ..| .|| .||.||| ||||.|   .. ...    .|..|||||...    .  .|. |||| |||||.|  |       |.  .||
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPY-WDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
| .|||.|||||| |||  . .. .| .  .   .. | .|  | ..|...|||.. .||.|||||.||.| |.||| 
WSCGVIFYILLCGKPPF--KGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase DCLK3.AA CAMKL 343-600 34 5.6e-108 345.71 In-house 1-297 (297) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-297/297
Sequence Identity: 34% (106 aa)

YDIGGVIGDGNFATVKECRH-RETKQAYAMKMIDKSQLKGKEDIVDS--------------EILIIQSLS---HPNIVKLHEVYETEAE------IYLIM
|.|| ..| |.|..|| ..| | |.. .|.|.|||. .. .. . .               || | ..|.   ||||.||.||.||.        |||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVQGGD--LFDAIVEN----VKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKY---V----VRPIFTVCGTPT
||..||.  ||| ||..     ..||.||  . . .. |. ..|...||||| ||||.|.  | .   ..|..|||.. .   .     .   | ||.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YVAPEILSE--K-GYGLEVDMWAAGVILYILLCGFPPFRSPER------DQDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQ
| ||||..   |  .| .||.|..||||| ..||  ||. .        .. .|...| .| ...  | |  .|  ..|| | .|.|.|.||.|..|...
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWI
||| 
HPWM

Kinase DCLK3.AA Pkinase 343-600 38 3.6e-105 360.48 Pfam 1-293 (293) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-293/293
Sequence Identity: 38% (114 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVD---SEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGG----DLFDAIV--EN
| ||..|| |.|..|..|.|. | . .|.| |.|.  | ..|. .   ||| | ..|.|||||.|....|.. .||..|||..||    |||| |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VKF--PEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAK---YVVRPIF-TVCGTPTYVAPEILS-EKGYGLEVDMWAA
 .|  .| |.  ... ....| ..|...|.|||.||||.|. .| . . ..|..||||||   |   . . |.|||| |.|||..   ..|| .||||..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYILLCGFPPFRSP----ERDQDELFNIIQVGQFEFLSPYWDNIS-----------------DAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
|.|||..||| |||..     ..||..... |  ....| .|.|..||                 ...||.....|..|||||.||||.|||||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase DCLK3.AA CAMK-Unique 343-600 28 1.3e-99 329.58 In-house 1-363 (363) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-363/363
Sequence Identity: 28% (102 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLK-GKEDI------------------VDSEILIIQSLSHPNIVKLHEV----YETEA-------
|. . .||.|||  |.||  |||.  .|.||. |   .  | ..                   . |. | ....||||.|| ..    ....        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------EIYLIMEYVQGGDLFDAIVE--------------------NVKFPE--PEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDK----
        ..|..|||.|||||||.|..                    . .| |   ...  .. |  |. .||...||||| |.||..|. ....    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------SITLKLADFGLAKYVV----RP-IFTVCGTPTYVAP--------------EILSEKGYGLEV----DMWAAGVILYILLCGFPPFRSPERDQ
           .||.||||....     .. . |.|||| |.||              |.. . .|.  .    | |. |||.|..||| ||| ..  | 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

------DELFNIIQVGQF-EFLSPYWDN---ISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
       |.|  |  |.. .| ...|.    ||..|||.| ....|||..| .|.. |.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase DCLK3.AA RSK 343-600 35 3.8e-96 325.74 In-house 1-278 (278) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVD-----SEILIIQSLS-HPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVK-
    | .| | . ....|.|. |.| |||| ..|. .. ..  .|      |. | .    ||.||.||....|| ..||||||. ||.||. . . .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQ--KDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--FPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKY-VVR---PIFTVCGTPTYVAPEILS----EKGYGLEVDMWA
  | | ||.. .  . .|. |.|.. |.||| |||| |    .  . ..|| |||..|. . .   .  | |.|  |.|||.|     ..|..  .| | 
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS

AGVILYILLCGFPPFRSPERD--QDELFNIIQVGQFEFLSPYWDNISDAAKDLVRNLLEVDPKKRYT-----AEQVLQHPWI
 ||..| .| |.|||.. ..|  ..|... || |.| . .| |...|..||||.| .|..||.||..     ||...||||.
LGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase DCLK3.AA Ciliate-E2 343-600 27 1.6e-95 323.69 In-house 1-365 (365) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)

YDIGGVIGDGNFATVKECRHRETKQAY------------------AMKMIDKSQLKGKE-DIVDSEILIIQ----------------SLSHPNIVKLHEV
|..  .|| |||..|..|....... .                  ..|.. . ..| ..  .. .|| |..                .|.||||.|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--TEAEIYLIMEYVQGGDLFDAIVEN-----------VKFPEPEAAVMITDLCK---------------ALVHMHDKN-IVHRDVKPENLLVQRNEDK
..  ..  |||.|||.||||||| | .|            .| | |.. ... ...               || ..| || |.||| ||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SITLKLADFGLAKYVVRP----------------------------------IFTVCGTPTYVAPEILS---------EKGYGLEVDMWAAGVILYILLC
   .|..||||.|..  .                                  ..|.|||| |.|||||.         .|||. ..|.|..|||||..|.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GFPPFRSPERDQDELFNIIQVGQFEFLSP--------------YWDNISDAAKDLVRN----LLEVDPKKRYT-AEQVLQHPWI
| |||          ...|. ....| .|               |...|. .||| ..    .|..||.||.| .||.|.|||.
GKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase DCLK3.AA Pkinase_Tyr 343-493 28 8.5e-22 74.45 Pfam 1-161 (270) Show / Hide
Range on Protein: 343-493
Range on HMM: 1-161/270
Sequence Identity: 28% (47 aa)

YDIGGVIGDGNFATVKECRHR----ETKQAYAMKMI-DKSQLKG--KEDIVDSEILIIQSL-SHPNIVKLHEVYE-TEAE--IYLIMEYVQGGDLFDAIV
  .| ..| |.| .|.... .    .||.  | ||. ...  .   .||    |. |  .| .|||||.|. |    .    ||..|||...||| |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----NVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYV
.    . ... ..   | .. .|.. . ..||..|||.   | || .    . . | .|||||...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDI

Kinase DCLK3.AA TyrKc 343-600 21 2.7e-16 40.69 SMART 1-280 (280) Show / Hide
Range on Protein: 343-600
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSL--SHPNIVKLHEVYETE-------AEIYLIMEYVQGGDLFDAIVEN
   | ..| |.| .| ... .   .  | ||. ..    .||.  .|. |  .|  .|||||.|. |  ..         ....|||. .||| | . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

VK-FPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRP--------IFTV----CGTP----TYVAPEILSEKG
 . .. ..   . .. ..   . |.||..|||    | || .|     | | .||||....             ..    .|         ||| . .. 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGLEVDMWAAGVILY-ILLCGFPPFRSPE---RDQDELFNIIQVGQFEFLSPY-----WDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI
.  . | |. || .. |.  | .|   ..    . .|... .. |      |.         .|.  .. .   . ||..| | ...  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF