Gene DCLK3 (Human)
DCLK3
Species: Human
Alias: DCAMKL3, DCLK3
External Links:
Annotation:
Sequence
Protein domains of DCLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | DCLK3.AA | DCAMKL | 356-613 | 61 | 5.8e-214 | 672.82 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-279/279 Sequence Identity: 61% (172 aa) YETGRVIGDGNFAVVKECRHRETR-QAYAMKI-----------------IDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG |..||.|||||||||.|||||||. ..||||| |||...||||.|.|.|. |.|...||.|..|.|...|....||..|||||| YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVR---PIFTVCGTPTYVAPEILSEKGYGLEV ||||||.|..||.|.|||.|...|||||...|...|||||.|||||||...||....|||.|||||.||.. |..||||||||||||||.|.|||..| DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV DMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI |.||||||||||||||||||||..||.|||..|. |.|||. ||||||||.||||.|..|.|||.|||||.|..||||. DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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| Kinase | DCLK3.AA | CAMK1 | 356-613 | 46 | 9.1e-150 | 438.58 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-276/276 Sequence Identity: 46% (130 aa) YETGRVIGDGNFAVVKECRHRET---RQAYAMKIID-KSRLKGKE----DMVDSEILIIQS---LSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAII || | .|| | |..|..| |.|| ..||.|.|| |. .|.|. .... || | .. ..||||.|..|.||.|...||..|.|.||.||| |. YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV ESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLK--LADFGLAKHVV-R--PIFTVCGTPTYVAPEILSE---KGYGLEVDM | .. | ||.. . ...|. .||.| |||||||||||| ... | ..| .|||||.| . .|.|||| |||||.| |.|. ..|| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDS-KIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM WAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDA-AKDLVSRLLVVDPKKRYTAHQVLQHPWI | .|||.||||||.||| . |. ..||| | . .|| |.|||||| |||... .|.||||||||. |.|.|||| WSIGVITYILLCGYPPFYD-ENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | DCLK3.AA | CAMK | 361-613 | 29 | 1.3e-136 | 443.04 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 361-613
Range on HMM: 1-425/425
Sequence Identity: 29% (125 aa)
VIGDGNFAVVKECRHRETR------------QAYAMKIIDKSRLKG---------------------------KEDMVDSEILIIQSLS-------HPNI
..| |.|..||.|.|..| | .|.|||||..||. ....| .|| | ..|. ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKLHEVYET-------------------DMEIYLIL---EYVQGG----DLFDAIIES---------------VKFPEPDAALMIMDLCKALVHMHDKSI
.||.||||. |...|... ||..|| |||| |.| .|.| .|. .. .| |. ..|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENLLVQRNEDKS-------------TTLKLADFGLAKHVVR--------------------------PIFTVCGTPTYVA-PEILS-------
|||||||||.|.. |.| | ..|..|||.|... . . |.|||| |.| ||.|.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------EKGYGLEVDMWAAGVILYILLCGFPPFRSPER-----------DQDELFNIIQLGHFEFLPPY------------WDNISDA--------AKD
...|| ..|||..||||||.|||.|||... . .. ||| |. | ..| ||| ||.||| .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LVSRLLVVDPKKRYTAHQVLQHPWI
|....|.|||.||.|..|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | DCLK3.AA | RAD53 | 356-613 | 37 | 3.1e-123 | 369.07 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-305/305 Sequence Identity: 37% (114 aa) YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDK-------SRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYET-DMEIYLILEYVQGGDLFDAIIESV | .....| |||..||.. ..|.| .|.||||| .. .|.| | .|. | . |.||.|........| . |..||.. ||.||. |. . YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK K----FPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQ-RNEDK-------------STTLKLADFGLAKHVVRP--IFTVCGTPTYVAPEILSE . | |... . .| |. ||. |.|||||||| | .|.. | .|..||||.| |. | ||||.|||||.. RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS K---------------GYGLEVDMWAAGVILYILLCGFPPFRSPERDQ----DELFNIIQL-GHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQV | ||. .||.| .|.||||.|||.||| | ...| . || | | ..| .|||| ||. ||||....|.|||.||||. .. KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF-SDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA LQHPWI |.|||. LNHPWM |
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| Kinase | DCLK3.AA | CDPK | 356-613 | 42 | 1.7e-113 | 349.41 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-271/271 Sequence Identity: 42% (117 aa) YETGRVIGDGNFAVVKECRHR-ETRQAY-AMKIIDKSRLKGKE--DMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILE--YVQGGDLFDAIIESVKF | ..|.| |.| .|. . |. | | ||||| |||.| || ... || | .| ||||.|. |.|. .. .|...| |. ||.||| ||| .| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF PEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKST---TLKLADFGLAKHVV-------RPIFTVCGTPTYVAPEILSEKGYGLEVDMWAA .| .||. . . |....|.. ||||||||||.| . ..| | ..|. |.|..| . . ||||.|.|||.| | | ..| | . TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI |||||||||| ||| . . | .. .. | ..| | ||.||| ||||....|..|||||..| |.|||||. GVILYILLCGYPPFYG--KNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | DCLK3.AA | S_TKc | 356-613 | 37 | 5.4e-110 | 372.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-231/231 Sequence Identity: 37% (104 aa) YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQG--GDLFDAIIESVK----- || .|.|| | |..|. |||..| . .|.|||. ... .|| | .. |||||||..|... ..|...||. | ||||| | . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -FPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGL-EVDMWAAGVILYIL ||| .|. .. .|.|| ..|.. |.||||||||.|. . ..|..|||||... |.|||| |.|||.| ||| ..|.|. |.|||.. PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQ-------HPWI ||| |||. .....|..| |. |||.....|..||.||.|| ..|| |||. LCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | DCLK3.AA | Ciliate-E2a | 356-613 | 38 | 2.3e-106 | 314.11 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-275/275 Sequence Identity: 38% (107 aa) YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKE---DMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEP |.. ..|| |||..|. .|..| . .|||...| .. .. . || |...|.|||| ||.||||.. .||..||..||.|.| |... .| | YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --DAALMIMDLC-KALVHMHDKSIVHRDLKPENLLVQ-RNEDKS--TTLKLADFGLAKHV--VRP--IFTVCGTPTYVAPEILSEKG------YGLEVDM ... .. | ..| .|| . |.||||||||.| .. ... . .|..|||||. . . .|. |||| |||||.| | |. .|| IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPY-WDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI | .|||.|||||| ||| . .. .| . . . | | | ..|...|||....|..|||||.|| | |.||| WSCGVIFYILLCGKPPF--KGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | DCLK3.AA | Pkinase | 356-613 | 37 | 4.8e-106 | 363.39 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-293/293 Sequence Identity: 37% (112 aa) YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVD---SEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG----DLFDAII--ES |..||.|| |.|..|..|.|. |.. .|.|||.|.. | ..|. . ||| | ..|.|||||.|....|.. .||...||..|| |||| | .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH VKF--PEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAK---HVVRPIF-TVCGTPTYVAPEILS-EKGYGLEVDMWAA .| .| .. .. ....| ..|...|.||||||||.|. .| . ....|..|||||| . . . |.|||| |.|||.. ..|| .||||.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLCGFPPFRSP----ERDQDELFNIIQLGHFEFLPPYWDNIS-----------------DAAKDLVSRLLVVDPKKRYTAHQVLQHPWI |.|||..||| |||.. ..||..... | . ..| |.|..|| ...||.....| .|||||.||.|.|||||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | DCLK3.AA | CAMKL | 356-613 | 34 | 1.5e-105 | 337.8 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-297/297 Sequence Identity: 34% (106 aa) YETGRVIGDGNFAVVKECRH-RETRQAYAMKIIDKSRLKG-------------KEDM-VDSEILIIQSLS---HPNIVKLHEVY-------ETDMEIYLI |. |...| |.|..|| ..| | |.. .|.|||||.... . || . || | ..|. ||||.||.||. || ..|||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV LEYVQGGD--LFDAIIES----VKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKH---V----VRPIFTVCGTP .||..||. ||| |.. ..||..| . .. |. ..|.. |||||.||||.|. | . ..|..|||.. . . . | ||.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP TYVAPEILSE--K-GYGLEVDMWAAGVILYILLCGFPPFRSPER------DQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVL | ||||.. | .| .||.|..||||| ..|| ||. . .. .|...| | .. || | .| ..|| ...|.|.|.||.|.||.. PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY--PPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM QHPWI .||| NHPWM |
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| Kinase | DCLK3.AA | CAMK-Unique | 356-613 | 29 | 5.5e-101 | 334.12 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 356-613
Range on HMM: 1-363/363
Sequence Identity: 29% (107 aa)
YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDK---SRLKGKE---------------DM-VDSEILIIQSLSHPNIVKLHEV----YETDM-------
|...|.||.||| .|.|| |||. .|.|.. | .. |.|. || . |. | ....||||.|| .. ....
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------EIYLILEYVQGGDLFDAIIE--------------------SVKFPE--PDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDK----
..|...||.|||||||.|.. .| | |... . | |. .||...|||||||.||..|. ....
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------STTLKLADFGLAKHVV----RP-IFTVCGTPTYVAP--------------EILSEKGYGLEV----DMWAAGVILYILLCGFPPFRSPERDQ
. .||.||||..|. .. . |.|||| |.|| |.. . .|. . | |. |||.|..||| ||| .. |
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
------DELFNIIQLGHF-EFLPPYWDN---ISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI
|.| | | . .| ..|. ||..|||.| ....|||..| .| . |.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | DCLK3.AA | RSK | 355-613 | 33 | 4.4e-95 | 322.2 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 355-613 Range on HMM: 1-278/278 Sequence Identity: 33% (94 aa) HYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKED---MVDSEILIIQSLS-HPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVK-- . . |. .| | . ....|.|. |.| ||||...|. .. .. . |. | . ||.||.||....|. ..|||.||. ||.||. . . . LKVLGQ-GGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG -FPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKH-VVR---PIFTVCGTPTYVAPEILS----EKGYGLEVDMWAA | | .|. . . .|. |.|.. |.|||||||| | . . ..|| |||..| . . . | |.| |.|||.| ..|.. .| | CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL GVILYILLCGFPPFRSPERD--QDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYT-----AHQVLQHPWI ||..| .| |.|||.. ..| ..|... || |.| . | |...|..||||....| .||.||.. | ...||||. GVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | DCLK3.AA | RSK | 356-613 | 38 | 7.1e-92 | 311.53 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-271/271 Sequence Identity: 38% (104 aa) YETGRVIGDGNFA---VVKECRHRETRQAYAMKIIDKSRLKGK-EDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPE || ..|| | | |.| |.|. |.| ||||||.|. .. | . | | ||.|||||.|... .|.|.. .|||||| . . |.| YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE PDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVV---RPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLC ... . .|. . | . |||||||||| |. . . ..|..|||.|| . | |.| |.|||.|. .|.. .| | ||..|. | REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLT GFPPFRSPERDQDELFNIIQ---LGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTA-----HQVLQHPWI |..|| ... |...|||| || | . ..||.||| ||||....| .|| .|..| |..||||. GCTPFQ--NKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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| Kinase | DCLK3.AA | Pkinase_Tyr | 356-504 | 27 | 2.7e-22 | 76.14 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 356-504 Range on HMM: 1-159/270 Sequence Identity: 27% (45 aa) YETGRVIGDGNFAVVKECRHR----ETRQAYAMKII-DKSRLKG--KEDMVDSEILIIQSL-SHPNIVKLHEVYE-TDME--IYLILEYVQGGDLFDAII . |...| |.| .|.... . .|.. | |.. ... . .||. |. | .| .|||||.|. | . ||...||...||| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR E----SVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAK . ... .| | .. .|.. . ..| ..|||| | || . . . | .|||||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLAR |
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| Kinase | DCLK3.AA | TyrKc | 356-613 | 20 | 7.2e-17 | 50.02 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 356-613 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSL--SHPNIVKLHEVYETD-------MEIYLILEYVQGGDLFDAIIES . |...| |.| .| ... . . | | . .. . . .|. | .| .|||||.|. | .. .....||. .||| | . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH VK-FPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRP--------IFTV----CGTP----TYVAPEILSEKG . .. .| . . .. . |.| ..|||| | || .| | | .||||.. . .. .| ||| . .. RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YGLEVDMWAAGVILY-ILLCGFPPFRSPE---RDQDELFNIIQLGHFEFLPPY-----WDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI . . | |. || .. |. | .| .. . .|... .. |. ||. .|. .. .. ||..| | .. | . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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