Gene N2 (M.brevicollis)

N2

Species: M.brevicollis
Alias: N2
External Links:
Annotation:

Classification

Group: PTP
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
N2.AA Protein None 2330 None Fasta, JSON

Protein domain

Protein domains of N2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TNFR N2.AA TNFR 172-207 24 0.128409 2.86 SMART 2-50 (50) Show / Hide 
Range on Protein: 172-207
Range on HMM: 2-50/50
Sequence Identity: 24% (12 aa)

L--APTSSSQ-------RVCSPVT-SVCPA---DTFLKAGATATSDTVC
   . . ...       . | | . . ||    ....|.  ||||.|||
KCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 187-207 27 0.767006 6.31 Pfam 20-41 (41) Show / Hide 
Range on Protein: 187-207
Range on HMM: 20-41/41
Sequence Identity: 27% (6 aa)

SVCPA-DTFLKAGATATSDTVC
..|.  ......  |.|..|||
TRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 213-255 17 0.050303 7.12 SMART 1-50 (50) Show / Hide 
Range on Protein: 213-255
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CQ--PNGYIAAFGDD---LSDNTCQTLTVCTD---HQFETSAATLSSDRQC
|.  .. | .  ..         |. .| |.     |....  |  |...|
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 235-255 22 14.976639 1.9 Pfam 20-41 (41) Show / Hide 
Range on Protein: 235-255
Range on HMM: 20-41/41
Sequence Identity: 22% (5 aa)

TVCTD-HQFETSAATLSSDRQC
|.|   .|....  |  ....|
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 323-346 40 0.006405 13.41 Pfam 17-41 (41) Show / Hide 
Range on Protein: 323-346
Range on HMM: 17-41/41
Sequence Identity: 40% (10 aa)

TACTTCAA-DQYQVATCTASTDRVC
..||.|   .|| |. ||.  ..||
LSCTRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 304-346 21 0.16071 1.84 SMART 1-50 (50) Show / Hide 
Range on Protein: 304-346
Range on HMM: 1-50/50
Sequence Identity: 21% (12 aa)

CK--AMRWWSIQ------LTCCRSTLVTACT--TCAA---DQYQVATCTASTDRVC
||  .   .. .       .|      ..|.  .|     .|| .. |||  ..||
CKCQEGHYCHHWNHTHYEPHC------LPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR N2.AA TNFR 352-394 23 0.036645 8.56 SMART 1-50 (50) Show / Hide 
Range on Protein: 352-394
Range on HMM: 1-50/50
Sequence Identity: 23% (12 aa)

CG---SGFYQLVAPTP--TTDRRCARVGACAV---HQYESSAATATSNVIC
|      ...  ..|    . ..|   . |      ||...  ||||| .|
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 518-533 50 0.004246 14.02 Pfam 26-41 (41) Show / Hide 
Range on Protein: 518-533
Range on HMM: 26-41/41
Sequence Identity: 50% (8 aa)

GLYEVAACTTTTNRQC
|.|.|. || | |..|
GQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 767-774 75 5.130699 3.49 Pfam 34-41 (41) Show / Hide 
Range on Protein: 767-774
Range on HMM: 34-41/41
Sequence Identity: 75% (6 aa)

TPTANTVC
|.| ||||
TWTQNTVC
TNFR N2.AA TNFR 804-846 19 0.063794 6.04 SMART 1-50 (50) Show / Hide 
Range on Protein: 804-846
Range on HMM: 1-50/50
Sequence Identity: 19% (10 aa)

CS--STQFQINAPTS---TTDRACQSLRECRE---TQYERRAPTATTDRVC
|     ...     .    . ..|. .. |..    ||. .  ||| ..||
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 826-846 31 5.87092 3.29 Pfam 20-41 (41) Show / Hide 
Range on Protein: 826-846
Range on HMM: 20-41/41
Sequence Identity: 31% (7 aa)

RECRE-TQYERRAPTATTDRVC
..| .  ||. .  |.| ..||
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 888-908 31 1.931068 4.94 Pfam 20-41 (41) Show / Hide 
Range on Protein: 888-908
Range on HMM: 20-41/41
Sequence Identity: 31% (7 aa)

TECQT-GQFQYADATASTDRVC
|.|.  ||.  .. |.  ..||
TRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 914-957 21 0.053853 6.81 SMART 1-50 (50) Show / Hide 
Range on Protein: 914-957
Range on HMM: 1-50/50
Sequence Identity: 21% (11 aa)

CQ--SQQFQVAAPTA---TTDRRCQNVSSGCGS---HQYRTAPATPTSDIVC
|.    ...          . ..|.   . | .    || ..| |.||. ||
CKCQEGHYCHHWNHTHYEPHCLPCR--HTRCPPEHMGQYMKQPCTATSNTVC
TNFR N2.AA TNFR 1022-1064 26 0.019748 11.37 SMART 1-50 (50) Show / Hide 
Range on Protein: 1022-1064
Range on HMM: 1-50/50
Sequence Identity: 26% (13 aa)

CD--AGEWASSAATLTSDTVCTPWS--ACPQ---GQLESVPPSRTSDRVC
|   .|.  .. . .     |.|..   ||    || .. | ..||..||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1044-1064 31 1.525298 5.29 Pfam 20-41 (41) Show / Hide 
Range on Protein: 1044-1064
Range on HMM: 20-41/41
Sequence Identity: 31% (7 aa)

SACPQ-GQLESVPPSRTSDRVC
. |.  || .. |  .|...||
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1033-1040 62 5.062016 3.51 Pfam 34-41 (41) Show / Hide 
Range on Protein: 1033-1040
Range on HMM: 34-41/41
Sequence Identity: 62% (5 aa)

TLTSDTVC
| |..|||
TWTQNTVC
TNFR N2.AA TNFR 1168-1213 24 0.130402 2.79 SMART 1-50 (50) Show / Hide 
Range on Protein: 1168-1213
Range on HMM: 1-50/50
Sequence Identity: 24% (13 aa)

CDG-VDEFLLLTGENVTLH--EQCVAVR--TCEPG--AEYASQSPTPTSDRVC
| .  ...    ..    |  ..|.. |  .|.|    .|..|. |.||..||
CKCQEGHYCHHWNHT---HYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1185-1213 35 0.889598 6.09 Pfam 12-41 (41) Show / Hide 
Range on Protein: 1185-1213
Range on HMM: 12-41/41
Sequence Identity: 35% (11 aa)

H-EQCVAVRTCEP-GAEYASQSPTPTSDRVC
| ..|.. ..|.| | .|..|. |.|...||
HVPHCLSCTRCHPMG-QYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1243-1285 17 0.049862 7.16 SMART 1-50 (50) Show / Hide 
Range on Protein: 1243-1285
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CS--ATSFEEAPPTV---SSDRACQPLSSCTL---YQYQTSAPTPTSDRAC
|   .  . . .      .  ..|. ...|.     || ..  |.||.. |
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1265-1285 27 14.095681 1.99 Pfam 20-41 (41) Show / Hide 
Range on Protein: 1265-1285
Range on HMM: 20-41/41
Sequence Identity: 27% (6 aa)

SSCTL-YQYQTSAPTPTSDRAC
..|   .|| ..  |.|... |
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1303-1310 50 8.504554 2.74 Pfam 34-41 (41) Show / Hide 
Range on Protein: 1303-1310
Range on HMM: 34-41/41
Sequence Identity: 50% (4 aa)

TSTSDAVC
|.|...||
TWTQNTVC
TNFR N2.AA TNFR 1316-1360 17 0.225015 0.31 SMART 1-50 (50) Show / Hide 
Range on Protein: 1316-1360
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CID-GQEYETVAPTL---SSQRECAVVRDACAS---DEYQIAASTPTSDRLC
| . . .| .    .   .  . |      | .   ..| ..  |.||.. |
CKCQEGHYCHHWNHTHYEPHCLPCR--HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1503-1528 22 0.001074 16.06 Pfam 15-41 (41) Show / Hide 
Range on Protein: 1503-1528
Range on HMM: 15-41/41
Sequence Identity: 22% (6 aa)

QCQACRACNS-TSFETRGCTASTDRQC
.|..|. |..  ..... ||.  ...|
HCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1494-1528 18 0.052105 6.96 SMART 2-50 (50) Show / Hide 
Range on Protein: 1494-1528
Range on HMM: 2-50/50
Sequence Identity: 18% (9 aa)

A--EATSTSD-------TQCQACR--ACNS---TSFETRGCTASTDRQC
   | . ...        .|..||   |..     .... |||  ...|
KCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1546-1553 62 6.583468 3.12 Pfam 34-41 (41) Show / Hide 
Range on Protein: 1546-1553
Range on HMM: 34-41/41
Sequence Identity: 62% (5 aa)

TSTSNRVC
|.|.|.||
TWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1578-1601 40 2.2e-05 21.8 Pfam 17-41 (41) Show / Hide 
Range on Protein: 1578-1601
Range on HMM: 17-41/41
Sequence Identity: 40% (10 aa)

ENCTQCAV-GTYEEIPCTVSSDTIC
..|| |   |.|.  |||  ..| |
LSCTRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1602-1625 36 0.000172 18.78 Pfam 17-41 (41) Show / Hide 
Range on Protein: 1602-1625
Range on HMM: 17-41/41
Sequence Identity: 36% (9 aa)

LLCEPCTG-GFFELEPCGGNSQTVC
| | .| . |... .||  .. |||
LSCTRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1569-1601 26 0.001597 18.95 SMART 1-50 (50) Show / Hide 
Range on Protein: 1569-1601
Range on HMM: 1-50/50
Sequence Identity: 26% (13 aa)

CS-------ATSN-----TQCENCT--QCAV---GTYEEIPCTVSSDTIC
|        ...|      .|. |.  .|     |.|.  |||  |.|.|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1650-1672 28 0.002561 14.77 Pfam 17-41 (41) Show / Hide 
Range on Protein: 1650-1672
Range on HMM: 17-41/41
Sequence Identity: 28% (7 aa)

EACRTCDS-NEFEITPCQP-GNRVC
..|..|.. ..... ||..  |.||
LSCTRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1628-1649 30 0.004133 14.06 Pfam 19-41 (41) Show / Hide 
Range on Protein: 1628-1649
Range on HMM: 19-41/41
Sequence Identity: 30% (7 aa)

CSICNS-SSYEAEACVARADTVC
|. |..  .|. . | .  .|||
CTRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1607-1649 24 0.007978 15.49 SMART 1-50 (50) Show / Hide 
Range on Protein: 1607-1649
Range on HMM: 1-50/50
Sequence Identity: 24% (13 aa)

CT--GGFFELEPCGGNSQT----VCELCS--ICNS---SSYEAEACVARADTVC
|.  .|..    |  ...|     |. |.   |..     |. . | |  .|||
CKCQEGHY----CHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1556-1577 34 0.011132 12.59 Pfam 19-41 (41) Show / Hide 
Range on Protein: 1556-1577
Range on HMM: 19-41/41
Sequence Identity: 34% (8 aa)

CDDCPE-GLLTTALCSATSNTQC
|  |.. |.  .. | .|.||.|
CTRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1655-1696 21 0.075569 5.27 SMART 1-50 (50) Show / Hide 
Range on Protein: 1655-1696
Range on HMM: 1-50/50
Sequence Identity: 21% (12 aa)

CD--SNEFEIT--------PCQPGNRVCQALTQCAE---AQYESEAPTPTTDRVC
|    ...  .         |.|    |. .|.| .    ||...  |.| ..||
CKCQEGHYCHHWNHTHYEPHCLP----CR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1676-1696 36 4.668795 3.63 Pfam 20-41 (41) Show / Hide 
Range on Protein: 1676-1696
Range on HMM: 20-41/41
Sequence Identity: 36% (8 aa)

TQCAE-AQYESEAPTPTTDRVC
| | .  ||...  |.| ..||
TRCHPMGQYMVQPCTWTQNTVC
TNFR N2.AA TNFR 1702-1745 17 0.051196 7.04 SMART 1-50 (50) Show / Hide 
Range on Protein: 1702-1745
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CVL-GATFEVVAPTP---TSNRGCRALSTCGL---GEYEVFPGNTTHDRIC
|   . ..             . || ...|     |.|...|.. |....|
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 N2.AA TNFR_c6 1725-1745 31 2.873972 4.35 Pfam 20-41 (41) Show / Hide 
Range on Protein: 1725-1745
Range on HMM: 20-41/41
Sequence Identity: 31% (7 aa)

STCGL-GEYEVFPGNTTHDRIC
..|   |.|.|.| . |... |
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 N2.AA TNFR_c6 1749-1771 34 8.334378 2.77 Pfam 20-41 (41) Show / Hide 
Range on Protein: 1749-1771
Range on HMM: 20-41/41
Sequence Identity: 34% (8 aa)

TRCADSSLQYQLSAPTSTSDRQC
|||   . ||  .  |.|....|
TRCHP-MGQYMVQPCTWTQNTVC
PTPc N2.AA PTPc 2015-2323 24 3.4e-66 227.15 SMART 1-308 (308) Show / Hide 
Range on Protein: 2015-2323
Range on HMM: 1-308/308
Sequence Identity: 24% (86 aa)

RAREDWHALEAEKDLLLDEAR---PENFSMAKRPGSL--RSNRYR-NILATNTNRVRLLGVP------PERDYINADHIVFPDEPHDLKYIMAQGPLQAT
  .| .  |....  .|..     ..... |..|     . |||. .|..   .||.|   |      .  ||||| .| ..  ..  .||..||||. |
GFWEEFERLQRMTPWDLMS-NYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHT

VNDFWTMVAQQGVGTIAMVTQLQEG--------GRDKCYPYWPQVVGERQTAGDVIVEHLSSYSDEFNTVHITELQLYYRS----------QSRVVRHCQ
..||| || ||.. .|.| ... |.        || ||  |||.     .| |. .|. .| .. . . ........ .            ..| |.| .
IEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCP-DDYTMRTFEVTNTGCNCKYSMACSETRTVTHYH

FLSWPDHGVPSDLEDLVRFQAQVCSCCIAVPM--MLGVVEMFTAMVFLQLETFQAEM----------PRPAPLLVHCSAGVGRSGVVVLSDVIANKVRHC
. .|||||||.. ... .|  || ..    |   |                     |          .. .| .||||||.||.|. .. |.. ..... 
YTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYM-N-------------------MVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN-

HTFCRMFEQTRKGYIPDVRTMVSIVRSQRPMTIQTLEQFTLLYDFALKKVL
               .|.  .|. .|.|||. .||.||.  .|. .|. ..
---------------VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Y_phosphatase N2.AA Y_phosphatase 2047-2320 28 1e-65 229.47 Pfam 1-243 (243) Show / Hide 
Range on Protein: 2047-2320
Range on HMM: 1-243/243
Sequence Identity: 28% (81 aa)

SLRSNRYRNILATNTNRVRLLGV--PPERDYINADHIVFPDEP--HDLKYIMAQGPLQATVNDFWTMVAQQGVGTIAMVTQLQEGGR-DK-CYPYWPQ-V
 .. |||..|..   .||.| ..  ..  ||||| .| .   |  .  .||..|||.. |..||| || ||.. .|.|.... |.||  | |..|||.  
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG---PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNK

VGERQTAGDVIVEHLSSYSDEFNTVHITELQLYYRS----QSRVVRHCQFLSWPDHGVPSD-LEDLVRFQAQVCSCCIAVPMMLGVVEMFTAMVFLQLET
.|. .| || .|.  | ..   . .........       ..| |.| ....|||||||..   ....|  || ..                        
EGQPMTYGDFQVTCVSEEH--CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP----------------------

FQAEMPRPAPLLVHCSAGVGRSGVVVLSDVIANKVRHCHTFCRMFEQTRKGYIPDVRTMVSIVRSQRPMTIQTLEQFTLLYDFALK
 . .... .| .||||||.||.|. .. |..  ...| .|.             |.  .|. .|.|||. .||.||.  .|.  | 
-NPDHGC-PPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTV-------------DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
PTPc_motif N2.AA PTPc_motif 2179-2320 23 9.1e-24 86.2 SMART 1-92 (92) Show / Hide 
Range on Protein: 2179-2320
Range on HMM: 1-92/92
Sequence Identity: 23% (34 aa)

VVRHCQFLSWPDH-----GVPSDLEDLVRFQAQVCSCCIAVPMMLGVVEMFTAMVFLQLETFQAEMPRPAPLLVHCSAGVGRSGVVVLSDVIANKVRHCH
 |.| ....||||     |||.  .....| ..| .                                  |..||||||.||.|.... |.. ..     
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------------------------------PIVVHCSAGCGRTGTFCAIDMMMQQ-----

TFCRMFEQTRKGYIPDVRTMVSIVRSQRPMTIQTLEQFTLLYDFALK
              .|.  .|  .|.|||. .||.||.  .|.  |.
--------------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE