Gene 29769 (M.brevicollis)

29769

Species: M.brevicollis
Alias: 29769
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
29769.AA Protein None 640 None Fasta, JSON

Protein domain

Protein domains of 29769.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 29769.AA SH2 5-58 40 4e-13 40.35 Pfam 1-57 (81) Show / Hide 
Range on Protein: 5-58
Range on HMM: 1-57/81
Sequence Identity: 40% (23 aa)

WQFGEISKDAADELLQKDGLEDGKFLVRIRPGHPEDYVLAVVFKG---RPTHHLVQK
| .| ||.  | .||.. | .|| |||| .  .| ||.| |...|   | .|  .|.
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQR
SH2 29769.AA SH2 3-90 35 4.2e-11 44.12 SMART 1-87 (87) Show / Hide 
Range on Protein: 3-90
Range on HMM: 1-87/87
Sequence Identity: 35% (32 aa)

NPWQFGEISKDAADELLQKDGLEDGKFLVRIRPGHPEDYVLAVVFKGRPTHHLVQKGVDGMFTVNK---KSFGPARSISEVVALFQTDTLP
 || .| ||.. |..||.. | .|| |||| .  .| |||| | .||.  | ....  ||.. .     ..|    |. | |. .|.  |.
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKF---PSL-ELVNHYQHNPLG
SprA-related 29769.AA SprA-related 105-321 7 0.000729 14.86 Pfam 1-169 (321) Show / Hide 
Range on Protein: 105-321
Range on HMM: 1-169/321
Sequence Identity: 7% (18 aa)

NLATPSSAPAPAAGGTEANDAAGELIMAHPEVVDGLFFVRGRGADRPGEYVITVVYKGKPTQHLVRQSSKGEEYTVNGKACTDCTTLGQVVKFLRSAHPF
.. |.|........| ...  |.    .                                                                        
MIITNSYPSISYYSGSPQGTEAARRNNT------------------------------------------------------------------------

WPVPLKDHVPAQGRSRSDSVKSTGSA----------------------------QGSASTTPVAAAAPLADAARREAEDKARREAEDKARR---------
           .. . ... .|. |.                            .||   .  |.... |.... .|.... ..|. ....         
-----------PRENIPQPSSSENSNNFPNSSSDATATSQTSTAVANDQSKQSEDGST-QPQFAKIFGQAQTQNGQASQEQQPQASQQNDEDKQEQERDE

-EVEGKARREAEDKARREAEDKARREAEDKARREAEDKARREAEESVEQQRRAHE
 . |...  .|..  . .|....  .... .   ... |... ... .|| ....
VGQEQPEQQQAQAG-FENATQQSQQRQQQDQQTRQQQ-AQQQEQQQQQQQQQQQQ
SH2 29769.AA SH2 134-198 23 1.973141 3.09 Pfam 18-81 (81) Show / Hide 
Range on Protein: 134-198
Range on HMM: 18-81/81
Sequence Identity: 23% (16 aa)

PEVVDGLFFVRGRGADRPGEYVITVVYKG---KPTQHLVRQSSKGEEYTVNGKACTDCTTLGQVVKFL
|.  || | || .    ||.|...|...|   . .   ...   |  | . |. .  . .| . | . 
PGNPDGTFLVRESES-TPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHK--FCSLQELVEHY
PDZ 29769.AA PDZ 466-546 18 1.3e-07 32.53 SMART 1-80 (80) Show / Hide 
Range on Protein: 466-546
Range on HMM: 1-80/80
Sequence Identity: 18% (18 aa)

VAFGFTVSSMWRVDAPDDEYGRYNIIKMIEPGSPAETGK------LEVEDIIKTIDG-MDVSHCDINELKAIVREREL-------KFEVVVVRPD
  .||....               .|. ..||.|||         | . |.|  ..| ..|.  .  .. |... ..        | ...|.||.
GGLGFSIVG-------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVE--NMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG