Gene 27857 (M.brevicollis)

27857

Species: M.brevicollis
Alias: 27857
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
27857.AA Protein None 1041 None Fasta, JSON

Protein domain

Protein domains of 27857.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 27857.AA SH2 83-166 22 4.4e-17 64.0 SMART 1-87 (87) Show / Hide 
Range on Protein: 83-166
Range on HMM: 1-87/87
Sequence Identity: 22% (20 aa)

APWYLAKMTNTAVMKTLQH--QPDGAFIIRDSPATAGSFALAYRHQNETHHALIHNTA-QGLVLGK-SEEPLSCLSELVLRFSQHYDV
 |||  ...   . . |..  .|||.|..|||  ..|...| .|.... .| .|. ..  . ...  .... ..| |||  .... ..
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 27857.AA SH2 85-164 27 3.8e-11 34.56 Pfam 1-81 (81) Show / Hide 
Range on Protein: 85-164
Range on HMM: 1-81/81
Sequence Identity: 27% (24 aa)

WYLAKMTNTAVMKTLQH--QPDGAFIIRDSPATAGSFALAYRHQN---ETHHALIHNTAQG-LVLGKSEEPLSCLSELVLRFSQHY
||  |..   . . |.   .|||.|..|.|  | |...|  |...   . .|  |..|..| . ..  .   . |.|||    .||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-FCSLQELV----EHY
SH2 27857.AA SH2 498-505 62 14.916745 0.51 Pfam 74-81 (81) Show / Hide 
Range on Protein: 498-505
Range on HMM: 74-81/81
Sequence Identity: 62% (5 aa)

VSELVRHY
..||| ||
LQELVEHY
SH2 27857.AA SH2 641-727 32 2.2e-11 45.06 SMART 1-87 (87) Show / Hide 
Range on Protein: 641-727
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

PPWYKPEMSRAEAVALIEF--EPTGSFVVRDNMDEPGRHIVTYVLNGALHHHEIERLPDNGGYCLTELRNFARPTLRELIEFYGSSEGH
 |||   .||.||..|      | |.|.|||   .||  ....  .|  .|  |.|..| |.|...|. .   |.| ||...|    . 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 27857.AA SH2 643-721 32 4.7e-07 22.53 Pfam 1-81 (81) Show / Hide 
Range on Protein: 643-721
Range on HMM: 1-81/81
Sequence Identity: 32% (27 aa)

WYKPEMSRAEAVALIEF--EPTGSFVVRDNMDEPGRHIVTYVLNG---ALHHHEIERLPDNGGYCLTELRNFARPTLRELIEFY
|| . .||.||  |      | |.|.||.   .||   .. . .|     .|  | |...  ||..|. . |  ..| ||.|.|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHKF--CSLQELVEHY
SH2 27857.AA SH2 764-851 28 1.2e-14 55.96 SMART 1-87 (87) Show / Hide 
Range on Protein: 764-851
Range on HMM: 1-87/87
Sequence Identity: 28% (26 aa)

PAWLQTNMPKAAALQVIAG--KPDGAFVVRSSESRTDCYVLSYMFRGQVHHELVRMVGDDQKVFFLNNAPHHTFQSLQNLIEFFEAPRRE
  |   |.... | |   .  .|||.|.|| |||   .||||....|.|.| ..|  .|  . ...   . ..|.||  |....  ..  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 27857.AA SH2 782-845 32 3e-11 34.86 Pfam 19-81 (81) Show / Hide 
Range on Protein: 782-845
Range on HMM: 19-81/81
Sequence Identity: 32% (22 aa)

GKPDGAFVVRSSESRTDCYVLSYMFRG---QVHHELVRMVGDDQKVFFLNNAPHHTFQSLQNLIEFF
|.|||.|.|| |||   .|.|| .. |   .|.|  ..  ..  ...   .     |.||| |.|..
GNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHK---FCSLQELVEHY
SH2 27857.AA SH2 952-1032 25 7e-06 26.71 SMART 1-87 (87) Show / Hide 
Range on Protein: 952-1032
Range on HMM: 1-87/87
Sequence Identity: 25% (22 aa)

SNWCCLNLSREEALARLPHK---EGAFIVRKSND--NFATLTMVANGKHFHVQVHDST-LGLHLKK-STAYQPNLSALVAFYMIAGQT
 .|.  |.||||| . | .    .|.|.|| |    .. .|..  .||  | ... .   . ..   .  . |.|  ||..|.   . 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 27857.AA SH2 954-1026 25 0.002287 11.71 Pfam 1-81 (81) Show / Hide 
Range on Protein: 954-1026
Range on HMM: 1-81/81
Sequence Identity: 25% (22 aa)

WCCLNLSREEALARLPH---KEGAFIVRKSNDNFA---TLTMVANG-----KHFHVQVHDSTLGLHLKKST-AYQPNLSALVAFY
| . ..||.||  .|     ..|.|.||.|        ||. . .|     ||...| .|     ..  ..  . ..|. || .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESES-TPGDYTLSVRDDGPGDRVKHYRIQRTDNG---GYYITGRHKFCSLQELVEHY