10565

Species: M.brevicollis
Alias: 10565
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
10565.AA Protein None 597 None Fasta, JSON

Protein domain

Protein domains of 10565.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 10565.AA SH2 15-97 25 8.5e-10 39.79 SMART 1-87 (87) Show / Hide
Range on Protein: 15-97
Range on HMM: 1-87/87
Sequence Identity: 25% (22 aa)

VPAYMPQITKARAREVLAN--ENSGTYLLRFSAN-SQAIVLTMTIGGKNRHFVLEEDDNRNYTFDF--EHSEPTIQQLLNYVEENGFL
 | |.  |... | . | |     |..|.|.| .  ...||..  .||..|......|.. | .|   ... |.. .|.|.   |   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 10565.AA SH2 18-91 23 8.3e-08 24.75 Pfam 2-81 (81) Show / Hide
Range on Protein: 18-91
Range on HMM: 2-81/81
Sequence Identity: 23% (19 aa)

YMPQITKARAREVLAN--ENSGTYLLRFSANSQ-AIVLTMTIGG---KNRHFVLEEDDNRNYTFDFEHSEPTIQQLLNYV
|.. |... | . | |     ||.|.|.| ...  ..|.   .|   ...|..  ..||..|    .|  ...|.| .. 
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 10565.AA SH2 121-202 30 1.5e-14 55.57 SMART 1-87 (87) Show / Hide
Range on Protein: 121-202
Range on HMM: 1-87/87
Sequence Identity: 30% (27 aa)

QPWYFDDIDRDTADTVLSS--KPIGTFLIRT--NRHGNLTLSSHAKQRVLHIPLNVERGGKYYVGD--MESCPSVQEMVYALANKYKK
||||. .|.|. |.  | .  .| |.||.|   .  | ..||   |..| |. .. .  ||||...   ...||. |.|         
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 10565.AA SH2 123-196 32 2.7e-13 40.87 Pfam 1-81 (81) Show / Hide
Range on Protein: 123-196
Range on HMM: 1-81/81
Sequence Identity: 32% (26 aa)

WYFDDIDRDTADTVLSS--KPIGTFLIRTNRH--GNLTLSSHAKQ---RVLHIPLNVERGGKYYVGDMESCPSVQEMVYAL
||. .| |  |   | .  .| ||||.|  .   |  |||   .    || |.  . . .|.||... . ..|.||.|.  
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY