Gene 23795 (M.brevicollis)

23795

Species: M.brevicollis
Alias: 23795
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Rin

Sequence

Name Sequence Type Origin Length Description Download
23795.AA Protein None 722 None Fasta, JSON

Protein domain

Protein domains of 23795.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 23795.AA SH2 169-261 23 1.9e-14 55.22 SMART 1-87 (87) Show / Hide 
Range on Protein: 169-261
Range on HMM: 1-87/87
Sequence Identity: 23% (23 aa)

QHVYRPDLDRIAATKVLED--QPQGTFLVRPSSQYKGQQVLCLSIHGIVVHFLVERFSGYIQREEVVDGVRIAG-DTLVFSTMPHLLAYHVYNSGK
|. |  ...|  | . |    .| |.||||.|.. .|. ||..  .| | |....|           ....|.. .   |..  .|....  |.. 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD--------GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 23795.AA SH2 172-255 25 4.8e-07 22.52 Pfam 2-81 (81) Show / Hide 
Range on Protein: 172-255
Range on HMM: 2-81/81
Sequence Identity: 25% (23 aa)

YRPDLDRIAATKVLED--QPQGTFLVRPSSQYKGQQVLCLSIHG---IVVHFLVERFSGYIQREEVVDGVRIAGDTLVFSTMPHLLAYH
| ... |  | . |    .| ||||||.|. ..|. .|..   |    | |. . |  .         |. |.|..  |.. ..|  ..
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG--------GYYITGRHK-FCSLQELVEHY
VPS9 23795.AA VPS9 503-588 30 1.1e-16 63.75 Pfam 1-91 (111) Show / Hide 
Range on Protein: 503-588
Range on HMM: 1-91/111
Sequence Identity: 30% (28 aa)

YETSIAFLQLMEKAKSPIRKLQHLLSGVKAITSAI----HESLGDRAALIGADEFLPLFIWVLHKADIRFPEAEVEYMSGLL-DPDIMAGE
.|. .  || |...|||. ||.....  | |....    ..| . ... .|||.|||..|.|. || ..   ..|.... .. .|| | ||
WEQAQQCLQKMNHYKSPREKLKCIMRCCKIICNCVNQFNNKSMSNPDYPFGADDFLPILIYVVIKANPPHLYSNVQFIQRFRMCPDRMSGE
RA 23795.AA RA 620-703 28 7.2e-08 29.64 Pfam 10-96 (96) Show / Hide 
Range on Protein: 620-703
Range on HMM: 10-96/96
Sequence Identity: 28% (26 aa)

PDIKAQMVYKTFPITRTMTAQEAIEMIRRKLRL-APDPRD-GL---FEVINDEYR-ALAPDEQPQALKGAWNHRLHAQGRCRFVFRRAPT
.|... . ||| ......|||| |... ||... ..||.|  |   | .  .| |  | ..|.|  .  .|. .    .. ||..|| . 
DDGCQGCTYKTIRVPKNTTAQEVIRQALRKFHIDEDDPDDYCLWEEFLCRHGEERRVLPDHECPLQIQMQWPRDE---CMRRFYLRRRED
VPS9 23795.AA VPS9 503-608 22 3e-06 8.93 SMART 2-120 (120) Show / Hide 
Range on Protein: 503-608
Range on HMM: 2-120/120
Sequence Identity: 22% (28 aa)

YETSIAFLQLMEKAK--SPIRKLQHLLSGVKAITSAIH-ESLGDRAALIGADEFLPLFIWVLHKADIRFPEAEVEYMSGLLDPDIMAGE-----------
 .   . . .|   |  ||  |.  ||   | |. .   .|   . .  |||.|||. | .. ..| |    .||||. ...|..  ||           
WHIEQIEYKFMQHYKMYSPCDKMKCLLRCCKVIYYLMETHS---KGEMMGADDFLPVLIYCIIQCDMRDLFSNVEYMMEFRYPKLLHGEEGYYWTNLQAA

--VLKNFDLQASPRLRTACFDD
   ....  .   .|  . | .
LNFIMGLTENHATPLDHEQFRE
RA 23795.AA RA 609-703 25 1.9e-05 25.37 SMART 1-102 (102) Show / Hide 
Range on Protein: 609-703
Range on HMM: 1-102/102
Sequence Identity: 25% (26 aa)

VQGFLYIYFEHPD-IKAQMVYKTFPITRTMTAQEAIEMIRRKLRLAP--DPRDGLFEVI--NDEYRALAPDEQPQALKGAWNHR--LHAQGRCRFVFRRA
 .. | .|.. |    ..  |||  .| ..|||. |.   .|..|..  ...  |.|.    ...| | |.|.|  .  .| ..    .|.  |||.|. 
HTHVLRVYMDDPKYNNCGQTYKTIRVTKRTTAQDVIQQLLEKFHLDDEDWEEYCLVECHPHHGKERVLPPHECPLQIMKNWPRDMMSPRQHMYRFVLRKR

PT
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DD