N14

Species: M.brevicollis
Alias: N14
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Rhombid-SH2

Sequence

Name Sequence Type Origin Length Description Download
N14.AA Protein None 664 None Fasta, JSON

Protein domain

Protein domains of N14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 N14.AA SH2 99-185 30 4.9e-13 50.56 SMART 1-87 (87) Show / Hide
Range on Protein: 99-185
Range on HMM: 1-87/87
Sequence Identity: 30% (27 aa)

AEYYHGELDAARAQRRLRAYGLHDGLFLIRS-EPGSEDFVLSLAHDRRVSEFLISAGTAVAARYTIDD--GPPFHDLDTLVAFYSERREG
 ..||| .. . |.. |...| .|| ||.|  |.   |.|||. ....|  ..|        .| ||.  ...|..|  ||..|.  . |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 N14.AA SH2 101-179 32 4.4e-12 37.31 Pfam 1-81 (81) Show / Hide
Range on Protein: 101-179
Range on HMM: 1-81/81
Sequence Identity: 32% (28 aa)

YYHGELDAARAQRRLRAYGLHDGLFLIR---SEPGSEDFVLSLAHDR---RVSEFLISAGTAVAARYTIDDGPPFHDLDTLVAFY
.||| .  . |.|.|.. | .|| ||.|   |.||.  ..||. .|    ||  . |         | | ... | .|  || .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD--YTLSVRDDGPGDRVKHYRIQRTDNG--GYYITGRHKFCSLQELVEHY

Rhomboid N14.AA Rhomboid 456-600 33 3.1e-36 131.48 Pfam 1-164 (164) Show / Hide
Range on Protein: 456-600
Range on HMM: 1-164/164
Sequence Identity: 33% (55 aa)

AENPDQGWR-ILTALFMHA-GAIHLLVMLYVQLSVGVPLERKAGWLRIALIYLISGCGG---NLVSALFVPNS--AQVGASGAVYGLVATALVDLMHCWR
.  . | || ..|..|.|| | .|||  .......|.||||. |..|..|||.||| .|   ||.|..| |.|    ||||||..|| . ..| . . ..
PVHRGQWWRPLFTYMFLHASGWWHLLFNMWWLWFFGIPLERIHGSWRFLLIYFISGIFGGVCNLMSWWFSPYSYHPSVGASGAIFGLMGAYWVMFPFNRW

LLKSPWVQLGTYLIQTAVLLLLGT--TPWLDNFA----------HVGGFLFGLLGGIVFLPYVT
....... . . ||  .. |..|.   ||.|..|          |.|||..|.| |......  
MMYFIPGMFFLPLIIIFWNLWFGFWHWPWIDWWAMGIMWVAWWAHIGGFIVGFLYGWILFRRPW