Gene 8842 (M.brevicollis)

8842

Species: M.brevicollis
Alias: 8842
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Myo-SH2

Sequence

Name Sequence Type Origin Length Description Download
8842.AA Protein None 634 None Fasta, JSON

Protein domain

Protein domains of 8842.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Myosin_head 8842.AA Myosin_head 118-330 25 1.9e-51 177.25 Pfam 470-744 (765) Show / Hide 
Range on Protein: 118-330
Range on HMM: 470-744/765
Sequence Identity: 25% (70 aa)

F-TDNQAILDLFFET--SGIFPTLREYTALATGRDEAFLQDLAQRQ-QDNA--RF-ART-KF-------ADVFRVQHYAGTIDYHVTGMIEKNRDPLPSE
. .|||.. ||   .   ||.. | | . .  . |. ||| | |.  . ..   |  .. .|       .  |.. ||||...|...| .|||.|||. .
YGFDNQPCCDLIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDD

LQAVLQKTSN-ALIELIFQP-----------------------------------NIEEMAS-SSVGEQFTSSLAALMFKMNTC---LPHFVRCIKPNGA
| ........  ..  .|..                                    . ..     |. || .....||  ...|    ||.|||||||  
LIELMWCSWDNPFMQELFPDWEWAEWAHMQIDFEADFHEEEFKRRYNRNGCQKGKQGKKKWFMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNEN

QKPKCYEDQVVVEQLRYTGMLE-TIRIRREGFAHRLTFEDVVQAYRGVCFDFTTRL------PPTRDNAAKIMAA
..|.  ....| .|||. |.|| .|||.|.||..|.|. . .| || .|... ...      . |.... ||. .
KQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEWNGDTKQGCEKILQH
MYSc 8842.AA MYSc 1-377 14 1.8e-21 -206.41 SMART 6-771 (771) Show / Hide 
Range on Protein: 1-377
Range on HMM: 6-771/771
Sequence Identity: 14% (115 aa)

L---------------------------------------------------------------------------------------------------
.                                                                                                   
FEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKENQCIII

----------------------------------------------------------------------------------------------------
                                                                                                    
SGESGAGKTENTKKIMQYLAAVSGQVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGERNYHIFY

-------------------------------------------------------------------------------------------GNLEFDDDN
                                                                                           ||.|| ...
QLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGNIEFEQGR

S--GEAAI-----CNVEFLEAAADNLGVTAESLGDGFLTEVKIVMKE---KFRKRVSADRAAIARDAVGKALYDRLFTYIVAKIDSGLRPADPLPEHEQC
.  ...|.      . | |..|.  |||..| | . ... .  . .|   . .|  .   |. ||||  ||.|.||| .|| .| . .          . 
NQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM---------HNY

CIGIL-----------------------------------------GASAAASPQVLGFT--DNQAILDLFFET----SGIFPTLREYTAL---ATGRDE
 ||.|                                          .     . .  |.  |||...||         |||. | | . .     | |.
FIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFID-FFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKGTDQ

AFLQDLAQR-----QQDNARFART-----------KFAD-VFRVQHYAGTIDYHVTGMIEKNRDPLPSELQAVLQKTSNALIELIFQPNIEEMAS-----
 ||. | ..       .. .|              ....  |...||||...| |.|..|||.|.|. .|....|...| .|  .|..  .  ..     
TFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTPQEK

---------------------------SSVGEQFTSSLAALMFKMNTCLPHFVRCIKPNGAQKPKCYEDQVVVEQLRYTGMLETIRIRREGFAHRLTFED
                           ..|| ||  .|. || ..|.| ||..||||||  .|| ...|..|  |||. |.||.|||||.||..|.....
SSQGKNKSRRKKRMMQMKKTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPYQE

VVQAYRGVCFDFTTRLPPTRDNAAKIMAACQAKQAGLNTQQAMA---DTLNTLDGWIVAKNKVFLK-YWHVDVLDSLMMP
 .| |.  |...  .   .. |    . ...| .| |.. ..     .     |.. . | |||.. . ..  |. ..  
FYQRYKMLCPPTWPNWGNPWKNQ-LFGDPKKACEAILQQLGE-YIQHQ-NWDPDMYQFGKTKVFFRNPGQLFHLEEMRER
Myosin_head 8842.AA Myosin_head 1-84 29 4.4e-11 37.86 Pfam 279-369 (765) Show / Hide 
Range on Protein: 1-84
Range on HMM: 279-369/765
Sequence Identity: 29% (27 aa)

LGNLE-FDDDNSGEAA--ICNVEFLEAAADNLGVTAESLGDGFLTEVKIVM----KEKFRKRVSADRAAIARDAVGKALYDRLFTYIVAKI
|||.. | .|...|.|    . | .|...  .|| .|..  .... .. .     .|.  |  . ..|. ||||. ||.|.|.| .|| .|
LGNMKGFKQDQNEEQAVVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRI
IQ 8842.AA IQ 379-399 52 1e-05 22.47 Pfam 1-21 (21) Show / Hide 
Range on Protein: 379-399
Range on HMM: 1-21/21
Sequence Identity: 52% (11 aa)

GAAATAIQAWYRGCLSRRRYA
 .||. ||||.|| | |..| 
HRAAIKIQAWWRGYLARKHYR
IQ 8842.AA IQ 377-399 52 0.000691 20.16 SMART 1-23 (23) Show / Hide 
Range on Protein: 377-399
Range on HMM: 1-23/23
Sequence Identity: 52% (12 aa)

PFGAAATAIQAWYRGCLSRRRYA
   .||. ||||.|| | |.|| 
RMHRAAIIIQAWWRGYLARKRYK
SH2 8842.AA SH2 511-587 40 1.2e-25 77.14 Pfam 1-81 (81) Show / Hide 
Range on Protein: 511-587
Range on HMM: 1-81/81
Sequence Identity: 40% (33 aa)

WFHGLLSRREAEDLLYD--SPVGTFLLRVSDRSF-NYALSIKHDK--AFFRHYRVTHAASGGYCVDGAASDFPTLAELVDFF
|.|| .|| |||.||.    | ||||.| |...   |.|| ..|     ..|||.   . |||.. |    |..|.|||...
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-FCSLQELVEHY
SH2 8842.AA SH2 509-593 38 1.9e-24 88.44 SMART 1-87 (87) Show / Hide 
Range on Protein: 509-593
Range on HMM: 1-87/87
Sequence Identity: 38% (34 aa)

YPWFHGLLSRREAEDLLYD--SPVGTFLLRVSDR-SFNYALSIKHDKAFFRHYRVTHAASGGYCVDG-AASDFPTLAELVDFFRHENLS
.||.|| .|| |||.||     | |.||.| |..    |.||....   ..|||. . ..|.|..|.     ||.| |||....|  |.
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG