Gene N6 (M.brevicollis)

N6

Species: M.brevicollis
Alias: N6
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Grb2

Sequence

Name Sequence Type Origin Length Description Download
N6.AA Protein None 255 None Fasta, JSON

Protein domain

Protein domains of N6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 N6.AA SH2 60-140 39 1.7e-37 111.92 Pfam 1-81 (81) Show / Hide 
Range on Protein: 60-140
Range on HMM: 1-81/81
Sequence Identity: 39% (33 aa)

WFHGRIKRVDAEKILLE-VQSDCAYLFRESETAPGTFSLSVRVSNPMGQVQVQHFKILRDEAG-KYFLWVTKFNSLNELINYH
|.|| | | .||..|..  . |...| ||||. || ..||||  .|  . .|.|..| |.. |  |  . .||.||.||....
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 N6.AA SH2 58-146 35 1.9e-31 111.69 SMART 1-87 (87) Show / Hide 
Range on Protein: 58-146
Range on HMM: 1-87/87
Sequence Identity: 35% (33 aa)

HGWFHGRIKRVDAEKILLEV-QSDCAYLFRESETAPGTFSLSVRVSNPMGQVQVQHFKILRDEAGKYFLWV---TKFNSLNELINYHKTASVS
. |.||.| | .||..|. . . | ..| |.||. || ..||||.       .|.|..| |.. |||...    .||.|| ||.|.... . .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-----GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH3 N6.AA SH3 1-57 38 2.1e-19 71.71 SMART 1-58 (58) Show / Hide 
Range on Protein: 1-57
Range on HMM: 1-58/58
Sequence Identity: 38% (23 aa)

MEAKALHDFAATQQDELSFTKGSILKVIDIDSDKNWYKAEQD--GRTGFVPSNYLDLSP
....||.|. |.. |||||.|| |. |.. | | .|.|.. .  |..|..||||. . .
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 N6.AA SH3_1 4-50 44 2.8e-18 64.59 Pfam 1-49 (49) Show / Hide 
Range on Protein: 4-50
Range on HMM: 1-49/49
Sequence Identity: 44% (22 aa)

KALHDFAATQQDELSFTKGSILKVIDIDSDKNWYKAEQD--GRTGFVPS
.||.|..|.| |||||.|| |..||. . |..|.|.. .  |..|..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 N6.AA SH3_2 2-56 30 2.9e-10 38.85 Pfam 1-68 (68) Show / Hide 
Range on Protein: 2-56
Range on HMM: 1-68/68
Sequence Identity: 30% (21 aa)

EAKALHDFAA-TQQDE-----LSFTKGSILKVI---DIDSDKNWYKA-EQ--DGRT--GFVPSNYLDLS
 .... |. . |  .|     |.|.|| ..|||   | |.| ||... |   .||.  |..||...   
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD-NWWWCWETIWGGRRMRGWFPSQWVEEC
SH3_3 N6.AA SH3_3 21-54 34 3.8e-05 18.72 Pfam 21-55 (55) Show / Hide 
Range on Protein: 21-54
Range on HMM: 21-55/55
Sequence Identity: 34% (12 aa)

KGSILKVIDIDSDKNWYKAEQDGRTGFV-PSNYLD
.|  ..||. ... .||| .  | ||.|  |.|. 
NGTKVNVIGCQNGYGWYKINYNGKTGWVLSSDYVS
SH3_1 N6.AA SH3_1 204-249 48 9.3e-23 79.6 Pfam 1-49 (49) Show / Hide 
Range on Protein: 204-249
Range on HMM: 1-49/49
Sequence Identity: 48% (24 aa)

TALYDFVPEEAGELRFRKGDFITVLDSSDK-DWWKGQCH--GETGLFPA
.||||.......|| |.|||.|.|.. ||  |||||.|.  |..|.||.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 N6.AA SH3 201-255 44 1.4e-22 82.26 SMART 1-58 (58) Show / Hide 
Range on Protein: 201-255
Range on HMM: 1-58/58
Sequence Identity: 44% (26 aa)

KTATALYDFVPEEAGELRFRKGDFITVLDSSDKDWWKGQCH--GETGLFPAAYV-RMN
... ||||. .....|| |.||| ||||. .| .||||.|.  |..|.||. || ...
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 N6.AA SH3_2 202-255 27 4.4e-12 45.19 Pfam 1-68 (68) Show / Hide 
Range on Protein: 202-255
Range on HMM: 1-68/68
Sequence Identity: 27% (19 aa)

TATALYDFVP-EEAGE-----LRFRKGDFITVL---DSSDKDWWKG-QC--HGET--GLFPAAYVRMN
 . .. |.|| . ..|     |.|.||| |.|.   | .. .||..     .|..  |.||  .|.  
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC