Gene 25437 (M.brevicollis)

25437

Species: M.brevicollis
Alias: 25437
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Crk

Sequence

Name Sequence Type Origin Length Description Download
25437.AA Protein None 411 None Fasta, JSON

Protein domain

Protein domains of 25437.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 25437.AA SH2 71-139 35 2.8e-24 73.1 Pfam 6-81 (81) Show / Hide 
Range on Protein: 71-139
Range on HMM: 6-81/81
Sequence Identity: 35% (27 aa)

VSRTDADSRLRG--TPEGTFIIRDSS-KGGSFVLSVSEGG---KVSHYKIDRRSPC-VYEIGDESFANLPEIIEFY
.|| .|  .|.    |.|||..|.|. . |...|||  .|   .| ||.| |   . .| .|.. |..|.|..|.|
ISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 25437.AA SH2 65-145 32 4.6e-19 70.57 SMART 1-87 (87) Show / Hide 
Range on Protein: 65-145
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

AVSLA-AVSRTDADSRLRG--TPEGTFIIRDSSK-GGSFVLSVSEGGKVSHYKIDRRSPCVYEIGD---ESFANLPEIIEFYKRHMLD
       .|| .|.. |..   |.|.|..|||..  |..||||  .||| ||.| |  .  | |..   ..| .| |....|... | 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH3_1 25437.AA SH3_1 173-220 38 2.4e-21 74.89 Pfam 1-49 (49) Show / Hide 
Range on Protein: 173-220
Range on HMM: 1-49/49
Sequence Identity: 38% (19 aa)

TALYNFNARDPEDLSFRKGEQLFVLEVTER-EWWKAQSRATRQIGMVPA
.||| ..|..|..|||.||....|.| ..  .|||...  |.| |..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 25437.AA SH3 170-227 37 6.1e-21 76.81 SMART 1-58 (58) Show / Hide 
Range on Protein: 170-227
Range on HMM: 1-58/58
Sequence Identity: 37% (22 aa)

TEATALYNFNARDPEDLSFRKGEQLFVLEVTEREWWKAQSRATRQIGMVPANYLKTAK
 .. |||...|..|..|||.||. . ||| .. .|||.. . | |.|..|.||..  .
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 25437.AA SH3_2 171-226 13 2e-07 28.92 Pfam 1-68 (68) Show / Hide 
Range on Protein: 171-226
Range on HMM: 1-68/68
Sequence Identity: 13% (9 aa)

EATALYNFNA-RDPED-----LSFRKGEQLFVL---EVTEREWWKAQSR-ATRQI--GMVPANYLKTA
 . .. .... .....     |.|.||... |.   .    .||... . ....   | .| ....  
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH3 25437.AA SH3 324-385 37 2.6e-10 41.52 SMART 1-58 (58) Show / Hide 
Range on Protein: 324-385
Range on HMM: 1-58/58
Sequence Identity: 37% (23 aa)

VVCRAKLDRNAKSFDKSALSFKAGDLIHVLHQPKNGLWRGKLVNGDSGKVGHFPFTLVELVD
...||. | .|   .   ||||.|| |.|| .  .| |.|.. .  .|..| || . ||..|
PYVRALYDYQA--QNPDELSFKKGDIITVLEKDDDGWWKGRCNR--TGQEGWFPSNYVEEID
SH3_2 25437.AA SH3_2 325-384 23 1.5e-08 32.81 Pfam 1-68 (68) Show / Hide 
Range on Protein: 325-384
Range on HMM: 1-68/68
Sequence Identity: 23% (17 aa)

VCRAKLDRNAKSFDKSA-----LSFKAGDLIHVL----HQPKNGLWRG-KL-VNGDSGKV--GHFPFTLVELV
..|.  |...   ...      |.||.||.|.|.    . . |. |..     .   |..  |.||.. || .
YYRVHCDYVP-ATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNW-WWCWETIWG---GRRMRGWFPSQWVEEC
SH3_1 25437.AA SH3_1 342-378 42 0.000578 16.56 Pfam 14-49 (49) Show / Hide 
Range on Protein: 342-378
Range on HMM: 14-49/49
Sequence Identity: 42% (16 aa)

LSFKAGDLIHVLHQPKN-GLWRGKLVNGDSGKVGHFPF
|||| || |||. . .. . |.|.. |.  |..| || 
LSFKKGDIIHVIEKSDDWDWWKGRCNNT--GQEGWFPS