Gene N18 (M.brevicollis)

N18

Species: M.brevicollis
Alias: N18
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: CH-SH2

Sequence

Name Sequence Type Origin Length Description Download
N18.AA Protein None 906 None Fasta, JSON

Protein domain

Protein domains of N18.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH N18.AA PH 33-147 18 6.4e-16 60.13 SMART 1-82 (82) Show / Hide 
Range on Protein: 33-147
Range on HMM: 1-82/82
Sequence Identity: 18% (21 aa)

PLCAGWMTKIGMHSGKWQARYFVLTPSALSYFADVGGKYKGAIPVKGVISIDGVRPGAPIAQEACTVAAKRPVGDHAIKITAKVDGNYRSFYLETPSDKD
... ||..| .  . .|. |.|||... |.|. |   |.|| ||.....  . .                      ...|.        ..|. ..|...
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P----------------------CFEIHH-DR----TYYFQCESEEE

FSIWLKTLQAVKDGK
.  |.. .|.. .  
MQEWMQAIQKAIHNN
PH N18.AA PH 33-145 20 8.6e-16 59.59 Pfam 1-92 (92) Show / Hide 
Range on Protein: 33-145
Range on HMM: 1-92/92
Sequence Identity: 20% (23 aa)

PLCAGWMTKIGMHSGKWQARYFVLTPSALSYFADVGGKYKGAIPVKGVISIDGVRPGAPIAQEACTVAAKRPVGDHAIKITAKVDGNYRSFYLETPSDKD
. . ||..| |  ...|. |.|||... |.|. | . ..|| ||....   . ...                  .| ..|.       |..|....|...
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDCQVTKVPDN----------------KRPHCFQIRT-DR---RTYYFQAESEEE

FSIWLKTLQAVKD
.  |.. .|..  
MNDWMQAIQSACR
SH2 N18.AA SH2 184-269 20 1e-06 29.13 SMART 1-87 (87) Show / Hide 
Range on Protein: 184-269
Range on HMM: 1-87/87
Sequence Identity: 20% (19 aa)

QPWWKPKWTEEQAAQVLTQ--GPEGAFFLTETPNKKHCFTVNLQTGNKVVKLILVFRKQDGRNYWCLGL---MFFEHILDFVMHYSRRPIN
|||   . . |.| | | .  .|.|.| . .  ... .... . .. . || ....|..|  . ....    . |. . . | ||.. |. 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG
CH N18.AA CH 655-753 24 1.6e-18 68.79 SMART 1-100 (100) Show / Hide 
Range on Protein: 655-753
Range on HMM: 1-100/100
Sequence Identity: 24% (26 aa)

DEREVRTWIEDCLQRALGTEPLAETLHDGVVLCEVMNALMP-GAVSHMNRSKMTFQQMENIGFALSAMANY----GLRDEYSFQTVDLFE----QQNMPG
 |.. . |....|     .. ... . ||||||...|...| ....  .     |..||||  .|...  |    |. ..  |...|...      ...|
QEETFLRWCNSHL----PVNNFSTDWKDGVVLCQLINKIRPQDSIDWWH----RFHCMENINYFLNFCEKYGMFLGVCCVVNFDPEDIVDGNNNRKDILG

VINALVHL
||  |. |
VIWCLMQL
CH N18.AA CH 656-758 21 2.7e-15 59.26 Pfam 1-119 (119) Show / Hide 
Range on Protein: 656-758
Range on HMM: 1-119/119
Sequence Identity: 21% (26 aa)

EREVRTWIEDCLQRA----LGTE--PL-AETLHDGVVLCEVMNALMPG---AVSHM----NRSKMTFQQMENIGFALSAMAN-YGLRDEYSFQTVDLFE-
|.. ..|....|...    .. .   .  . . |||.|| ..... ||    ...     .|. | |..||||  ||..... .|..    |.. |... 
EKAFLRWCNRHLEKYGHWGVPITPVNFFFTDWRDGVALCALIHKYCPGLLIDWKKVFPPRMRK-MPFHCMENINYALDFCEKKLGCPCVNLFDPEDIVYM

-QQNMPGVINALVHLKSLAS
 . |.. |.  | .|.   .
PDGNPKSVMTYLWQLMHHFQ